Droxef LB 500mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing, or severe rash.
- Severe diarrhea with blood or mucus, fever, or abdominal cramps (possible Clostridioides difficile infection).
- Signs of kidney problems: decreased urine output, swelling in legs, or fatigue.
- Unusual bleeding or bruising, which may indicate a blood disorder.
- Yellowing of skin or eyes, dark urine, or severe abdominal pain (possible liver issue).
- Seizures, especially in patients with kidney disease.
- Persistent fever or worsening of infection symptoms after 48-72 hours of treatment.
If experiencing severe symptoms, call emergency services immediately.
What is SB Drox 500mg Tablet used for?
This medicine is a combination of cefadroxil, an antibiotic, and lactobacillus acidophilus, a probiotic. It is used to treat bacterial infections of the skin, throat, urinary tract, and respiratory tract. The antibiotic kills bacteria, while the probiotic helps protect gut health during treatment.
- Generic Name: Cefadroxil (500mg) + Lactobacillus Acidophilus (60Million spores)
- Manufacturer: SBS Biosciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 SB Drox 500mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफाड्रोक्सिल और लैक्टोबैसिलस एसिडोफिलस का संयोजन है। इसका उपयोग त्वचा, गले, मूत्र मार्ग और श्वसन तंत्र के बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। सेफाड्रोक्सिल बैक्टीरिया को मारता है और लैक्टोबैसिलस एसिडोफिलस पेट के अच्छे बैक्टीरिया की रक्षा करता है। यह दवा वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और उल्टी शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। कुछ लोगों को त्वचा पर चकत्ते, खुजली या योनि में यीस्ट संक्रमण हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, गंभीर दस्त और रक्त विकार शामिल हो सकते हैं। यदि आपको कोई गंभीर या लगातार लक्षण महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और बेहतर महसूस होने पर भी कोर्स पूरा करें। पेट की परेशानी कम करने के लिए इसे भोजन के साथ लें। दिन भर पर्याप्त पानी पिएं। इस दवा के साथ शराब न पिएं। यदि आपको गुर्दे या यकृत की बीमारी है या एलर्जी की समस्या है तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। यदि त्वचा पर चकत्ते, सूजन या सांस लेने में कठिनाई हो तो तुरंत आपातकालीन चिकित्सा सहायता लें।
💊 SB Drox 500mg Tablet Uses & Benefits
[{"condition":"Skin and soft tissue infections","description":"Treats bacterial infections of the skin such as cellulitis, abscesses, and wound infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Pharyngitis and tonsillitis","description":"Used to treat bacterial throat infections, including those caused by Streptococcus pyogenes, when antibiotics are appropriate.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated urinary tract infections caused by susceptible bacteria such as Escherichia coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"May be used for upper and lower respiratory tract infections when caused by susceptible bacteria.","evidence":"Moderate"},{"condition":"Bone and joint infections","description":"Sometimes used for bone infections (osteomyelitis) and joint infections after culture and sensitivity testing.","evidence":"Limited"}]
Off-label uses: [{"condition":"Acne vulgaris","description":"Occasionally prescribed off-label for inflammatory acne, but not a first-line treatment.","evidence":"Limited"},{"condition":"Prophylaxis before dental procedures","description":"May be used in patients with certain heart conditions to prevent infective endocarditis, but only under specialist guidance.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Skin infections, Throat infections, Urinary tract infections, Respiratory tract infections
📋 Drug Information
| Generic Name(s) | Cefadroxil (500mg) + Lactobacillus Acidophilus (60Million spores) |
| Brand Name | SB Drox 500mg Tablet |
| Manufacturer | SBS Biosciences |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. Do not refrigerate unless specified by the manufacturer. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise stated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefadroxil, the antibiotic component of this medicine, works by binding to specific penicillin-binding proteins inside the bacterial cell wall. This binding inhibits the final step of peptidoglycan synthesis, which is essential for the strength and structure of the bacterial cell wall. As a result, the bacteria cannot maintain their cell wall integrity and eventually die. Lactobacillus acidophilus is a probiotic that helps maintain a healthy balance of intestinal flora, which can be disrupted by antibiotic therapy. It does not have antibacterial action against the infection itself but supports gut health during treatment.
Mechanism Steps
💡 How to Take SB Drox 500mg Tablet
Strength: Each tablet contains Cefadroxil 500 mg and Lactobacillus Acidophilus 60 million spores.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for most infections is 500 mg to 1 gram taken once or twice daily, depending on the type and severity of the infection. For skin infections, 500 mg twice daily is common. For urinary tract infections, 500 mg once daily or twice daily may be used. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and clinical response. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced kidney function and may require dose adjustment. The dose should be individualized by a clinician based on renal function. Monitor for signs of toxicity and superinfection. |
| Renal Impairment | In patients with kidney impairment, the dose of cefadroxil should be adjusted based on creatinine clearance. For creatinine clearance between 10-25 mL/min, the dose may be reduced or the interval extended. For creatinine clearance less than 10 mL/min, further reduction is needed. Consult a doctor for precise dosing. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. However, use with caution in patients with severe liver disease and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose of cefadroxil is 4 grams per day, but this must be determined by a qualified clinician based on the patient's condition and renal function. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of SB Drox 500mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Gentamicin | Major | |
| Furosemide | Major | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Methotrexate | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Warfarin
- Aminoglycosides (e.g., gentamicin)
- Loop diuretics (e.g., furosemide)
⚡ Moderate Interactions
- Probenecid
- Oral contraceptives
- Methotrexate
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach upset, nausea, and vomiting while taking this medicine. It is best to avoid alcohol during the course of treatment to ensure optimal recovery and reduce strain on the liver and stomach.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefadroxil, other cephalosporins, or any component of the formulation","History of severe immediate hypersensitivity reaction to penicillin","Galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption (due to lactose content in some formulations)","Use in patients with phenylketonuria if the formulation contains aspartame"]
⚠️ Warnings & Precautions
["Before starting this medicine, inform your doctor about all your medical conditions, especially kidney disease, liver disease, or allergies.","Use with caution in patients with a history of penicillin allergy due to potential cross-reactivity.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi. Monitor for superinfection.","If severe diarrhea occurs, consider Clostridioides difficile-associated diarrhea. Discontinue and consult a doctor.","Do not use this medicine to treat viral infections such as the common cold or flu.","Complete the full course as prescribed, even if symptoms improve, to prevent antibiotic resistance.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Avoid alcohol while taking this medicine to reduce stomach upset."]
🤱 Lactation Safety
Cefadroxil is excreted in small amounts in breast milk. It is generally considered safe during breastfeeding, but monitor the infant for diarrhea, thrush, or rash. Lactobacillus acidophilus is a probiotic and is considered safe during lactation. Consult your doctor before use.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, stomach pain, and diarrhea. In severe cases, it may lead to seizures, especially in patients with kidney disease. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases with renal failure.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Take it with food to reduce stomach upset. Drink plenty of water throughout the day. Avoid alcohol while taking this medicine as it may worsen stomach side effects. Inform your doctor if you have kidney disease, liver disease, or a history of allergies. Do not share this medicine with others. Keep out of reach of children. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. If you develop a rash, swelling, or difficulty breathing, seek emergency medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can affect the elimination of cefadroxil. Dose adjustment may be necessary. They are also at higher risk of drug interactions due to multiple medications. Monitor for signs of superinfection and renal impairment.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Cefadroxil is generally considered safe during pregnancy, but the decision to use it should be made by your doctor based on the potential benefits and risks. Lactobacillus acidophilus is considered safe.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent or treat surgical site infections. Follow your surgeon's instructions carefully. Inform your surgeon if you have any allergies or kidney problems. Complete the full course as prescribed.
🦷 Dental Procedures
If you are undergoing dental procedures, inform your dentist if you are taking this medicine. It may be used prophylactically in certain patients with heart conditions to prevent infective endocarditis. Do not self-medicate; follow your dentist's advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine, but if you feel weak, dizzy, or have a fever, rest and avoid strenuous activities. Listen to your body and consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you feel better. Most people can continue their normal daily activities, but take it easy if you have a fever or feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to a relapse of the infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they may advise you to stop or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to antibiotic resistance, superinfection with fungi or resistant bacteria, and disruption of gut flora. Regular monitoring of kidney and liver function may be needed if used for extended periods. Always follow your doctor's advice regarding duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help maintain gut health during and after antibiotic therapy.
Evidence: Well-establishedRegular handwashing and wound care can prevent bacterial infections.
Evidence: Well-establishedHelps flush out bacteria from the urinary tract and supports overall recovery.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor, as antibiotics may affect the vaccine's effectiveness. Generally, antibiotics do not interfere with most vaccines, but it is best to consult your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from light and moisture. If crossing time zones, continue taking the medicine at the same intervals as prescribed; you may need to adjust the timing gradually. Check local customs regulations for carrying prescription medicines. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, taking it with food helps reduce stomach upset.
A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: It is generally considered safe, but you must consult your doctor before use.
A: It is best to avoid alcohol as it may worsen stomach side effects.
🤔 Common Patient Concerns
🔄 Substitutes for SB Drox 500mg Tablet
View AllAlternative brands with exact same active ingredient:
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cefadron lb 500mg tabletAgron Remedies Pvt Ltd ₹29.25 64.5% CHEAPER
-
cefrus-lb tabletBonsai Pharma ₹65.63 20.4% CHEAPER
-
oysidrox 500mg tabletOyster Labs Ltd ₹69.80 15.4% CHEAPER
-
droxef lb 500mg tabletMediwin Pharmaceuticals ₹75.94 8% CHEAPER
-
Remdrox LB 500mg CapsuleRemedies Pharmaceuticals (India) Ltd ₹77.81 5.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full prescribed course to prevent the infection from returning and to avoid antibiotic resistance. - Myth: Probiotics in antibiotics are unnecessary.
Fact: Lactobacillus acidophilus helps maintain gut health and may reduce antibiotic-associated diarrhea.
🔄 Alternative Options
Generic Alternatives
- Cefadroxil 500 mg + Lactobacillus acidophilus 60 million spores tablet