Allsef 125mg Tablet: Uses, Side Effects, and Safety Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing.
- Severe or bloody diarrhoea that does not stop.
- Signs of a severe skin reaction: painful rash, blistering, or peeling skin.
- Unusual bruising or bleeding.
- Decreased urine output or swelling in the legs.
- Seizures.
- Yellowing of the skin or eyes (jaundice).
If experiencing severe symptoms, call emergency services immediately.
What is Sayfurox 125mg Tablet used for?
This medicine is an antibiotic containing cefuroxime 125 mg, used to treat bacterial infections of the chest, throat, ears, urinary tract, and skin. It works by killing bacteria. Take it with food as prescribed.
- Generic Name: Cefuroxime (125mg)
- Manufacturer: Alobiote Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Sayfurox 125mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक है जिसमें सेफ्यूरोक्सिम 125 मिलीग्राम होता है। यह बैक्टीरिया के कारण होने वाले संक्रमणों जैसे छाती, गले, कान, साइनस, मूत्र मार्ग, त्वचा और श्वसन तंत्र के संक्रमण के इलाज में उपयोग की जाती है। यह बैक्टीरिया को मारकर काम करती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द, सिरदर्द और त्वचा पर चकत्ते शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी, गंभीर दस्त और रक्त विकार शामिल हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं कि आपको सेफ्यूरोक्सिम, अन्य सेफलोस्पोरिन या पेनिसिलिन से एलर्जी है या नहीं। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। इस दवा को भोजन के साथ लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। शराब का सेवन न करें। गंभीर दस्त होने पर तुरंत डॉक्टर से मिलें।
💊 Sayfurox 125mg Tablet Uses & Benefits
[{"condition":"Upper respiratory tract infections","description":"Used to treat infections of the throat, tonsils, sinuses, and ears caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Lower respiratory tract infections","description":"Effective against community-acquired pneumonia and acute exacerbations of chronic bronchitis.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Used for uncomplicated urinary tract infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats infections such as cellulitis, impetigo, and wound infections.","evidence":"Well-established"},{"condition":"Early Lyme disease","description":"Used to treat early stages of Lyme disease caused by Borrelia burgdorferi.","evidence":"Well-established"},{"condition":"Gonorrhoea","description":"Used as an alternative treatment for uncomplicated gonorrhoea.","evidence":"Established"}]
Off-label uses: [{"condition":"Prophylaxis in dental procedures","description":"Sometimes used to prevent infection in patients with certain heart conditions undergoing dental work.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Upper respiratory tract infections, Lower respiratory tract infections, Urinary tract infections, Skin infections, Lyme disease
📋 Drug Information
| Generic Name(s) | Cefuroxime (125mg) |
| Brand Name | Sayfurox 125mg Tablet |
| Manufacturer | Alobiote Healthcare |
| Packaging / Form | strip of 4 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep out of reach of children. |
| Shelf Life | Typically 24 months from the date of manufacture. Check the expiry date on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to specific proteins called penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the final step of cell wall synthesis, leading to a weakened cell wall and ultimately causing the bacteria to burst and die. It is bactericidal, meaning it kills bacteria directly. It is effective against a wide range of gram-positive and gram-negative bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus (methicillin-sensitive strains).
Mechanism Steps
💡 How to Take Sayfurox 125mg Tablet
Strength: This medicine is available as a 125 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for most infections is 250 mg to 500 mg taken twice daily, depending on the type and severity of the infection. For uncomplicated urinary tract infections, a dose of 125 mg twice daily may be used. For early Lyme disease, the dose is usually 500 mg twice daily for 20 days. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function and may require dose adjustment. Your doctor will determine the appropriate dose based on your kidney function. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine may need to be reduced. For creatinine clearance between 10 and 20 mL/min, the usual dose may be given every 24 hours. For creatinine clearance less than 10 mL/min, the usual dose may be given every 48 hours. Dose adjustment must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment, as cefuroxime is not significantly metabolized by the liver. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 1 gram (1000 mg) per day, except for specific indications like Lyme disease where up to 1 gram per day may be used. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Sayfurox 125mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Probenecid | Major | |
| Antacids | Moderate | |
| H2 blockers | Moderate | |
| Proton pump inhibitors | Moderate | |
| Oral contraceptives | Moderate | |
| Loop diuretics | Minor |
🚨 Major Interactions
- Warfarin
- Probenecid
- Oral contraceptives
⚡ Moderate Interactions
- Antacids (e.g., aluminium/magnesium hydroxide)
- H2 blockers (e.g., ranitidine)
- Proton pump inhibitors (e.g., omeprazole)
🍷 Alcohol Interaction
Alcohol may worsen certain side effects such as nausea, dizziness, and stomach upset. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefuroxime or other cephalosporins","Severe allergy to penicillins (cross-reactivity possible)","Previous severe allergic reaction to any beta-lactam antibiotic"]
⚠️ Warnings & Precautions
["Use with caution in patients with kidney disease; dose adjustment may be needed.","May cause Clostridioides difficile-associated diarrhoea; if severe diarrhoea occurs, stop the medicine and consult a doctor.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","May reduce the effectiveness of oral contraceptives; use additional contraception.","Prolonged use may lead to fungal or bacterial superinfections.","Inform your doctor if you have a history of colitis."]
🤱 Lactation Safety
Cefuroxime is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose may cause nausea, vomiting, and diarrhoea. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Haemodialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before taking this medicine, tell your doctor if you are allergic to cefuroxime, other cephalosporins, or penicillins. Inform your doctor about all other medicines you are taking, especially blood thinners, antacids, and diabetes medicines. Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop taking it early, even if you feel better. Take this medicine with food to help it absorb better and to reduce stomach upset. If you have kidney problems, your doctor may need to adjust your dose. If you are pregnant or breastfeeding, consult your doctor before taking this medicine. Avoid alcohol while taking this medicine as it may worsen side effects. If you develop a severe or bloody diarrhoea, stop taking this medicine and contact your doctor immediately. Do not share this medicine with others, even if they have the same symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and may require dose adjustment. Monitor for signs of toxicity.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Cefuroxime is generally considered safe, but the decision should be individualized.
🏥 Post-Surgery Considerations
This medicine may be used to prevent or treat surgical site infections. Follow your surgeon's instructions regarding dosing and duration.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may be used prophylactically before dental procedures in certain heart conditions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue while taking this medicine, avoid strenuous exercise or operating heavy machinery until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating machinery. Otherwise, it usually does not significantly impact daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early may cause the infection to return and contribute to antibiotic resistance. If you experience severe side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance and superinfections. It is generally prescribed for short courses. Prolonged use should be monitored by a doctor, including periodic assessment of kidney and liver function.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help prevent antibiotic-associated diarrhoea.
Evidence: ModerateFor viral infections, rest and fluids are more appropriate.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Consult your doctor about vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture and heat. If crossing time zones, adjust dosing times gradually under medical guidance. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2 to 3 days, but it is important to complete the full course as prescribed.
A: Yes, take this medicine with food to improve absorption and reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Cefuroxime is generally considered safe during pregnancy when clearly needed. However, consult your doctor before use.
A: It is advisable to avoid alcohol as it may worsen side effects such as nausea and dizziness.
🤔 Common Patient Concerns
🔄 Substitutes for Sayfurox 125mg Tablet
View AllAlternative brands with exact same active ingredient:
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bid kid 125mg tabletKopran Ltd ₹18.81 70.6% CHEAPER
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ceftil 125mg tabletStallion Laboratories Pvt Ltd ₹24.08 62.4% CHEAPER
-
cefuxime 125mg tabletNectar Biopharma Pvt Limited ₹25.00 60.9% CHEAPER
-
cefpil 125mg dry syrupPsychotropics India Ltd ₹35.45 44.6% CHEAPER
-
ceface 125mg tabletParenteral Drugs India Ltd ₹39.00 39.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course to prevent the infection from returning and to avoid antibiotic resistance. - Myth: Antibiotics can be shared with others.
Fact: Never share antibiotics. They are prescribed for a specific infection and person.
🔄 Alternative Options
Generic Alternatives
- Cefuroxime 125 mg tablet
Brand Alternatives
- Allsef 125mg tablet