Saaz-DS Tablet DR (Sulfasalazine 1000mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Sore throat, fever, or mouth ulcers
If experiencing severe symptoms, call emergency services immediately.
What is salday 1000mg tablet used for?
This medicine is a delayed-release tablet containing sulfasalazine 1000 mg, used to treat rheumatoid arthritis, ulcerative colitis, and Crohn's disease. It works by reducing inflammation in the joints and intestines. Take it with food and water, and follow your doctor's monitoring schedule.
- Generic Name: Sulfasalazine (1000mg)
- Manufacturer: Reign Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 salday 1000mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सल्फासालाज़ीन 1000 मिलीग्राम युक्त एक डिलेड-रिलीज़ टैबलेट है, जिसका उपयोग रूमेटॉइड आर्थराइटिस, अल्सरेटिव कोलाइटिस और क्रोहन रोग के इलाज के लिए किया जाता है। यह जोड़ों और आंतों की सूजन को कम करने में मदद करती है। इसे भोजन के साथ और पानी के साथ लें, और अपने डॉक्टर की सलाह का पालन करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट की गड़बड़ी, भूख न लगना, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में रक्त विकार, यकृत की क्षति, गुर्दे की समस्या, और त्वचा पर गंभीर प्रतिक्रियाएँ हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। टैबलेट को पूरा निगलें, चबाएं नहीं। इसे भोजन के साथ लें। पर्याप्त पानी पिएं। शराब से बचें। बिना डॉक्टर की सलाह के कोई नई दवा शुरू या बंद न करें। नियमित रक्त जांच कराएं। इसे ठंडी और सूखी जगह पर रखें।
💊 salday 1000mg tablet Uses & Benefits
[{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness, and slows joint damage in adults with active rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ulcerative colitis","description":"Helps induce and maintain remission in mild to moderate ulcerative colitis by reducing bowel inflammation.","evidence":"Well-established"},{"condition":"Crohn's disease","description":"May be used to treat active Crohn's disease and maintain remission, especially involving the colon.","evidence":"Moderate"},{"condition":"Ankylosing spondylitis","description":"Sometimes used to reduce pain and stiffness in ankylosing spondylitis, though evidence is limited.","evidence":"Limited"},{"condition":"Psoriatic arthritis","description":"May be used off-label to treat joint symptoms in psoriatic arthritis.","evidence":"Limited"}]
Off-label uses: [{"condition":"Behçet's disease","description":"Sometimes prescribed to manage symptoms of Behçet's disease, a rare inflammatory disorder.","evidence":"Limited"},{"condition":"Uveitis","description":"May be used off-label to treat certain types of eye inflammation.","evidence":"Limited"}]
Primary treatment for: Rheumatoid arthritis
Also treats: Ulcerative colitis, Crohn's disease, Ankylosing spondylitis, Psoriatic arthritis
📋 Drug Information
| Generic Name(s) | Sulfasalazine (1000mg) |
| Brand Name | salday 1000mg tablet |
| Manufacturer | Reign Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Non biologics |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Sulfasalazine is a prodrug that is cleaved by colonic bacteria into sulfapyridine and 5-aminosalicylic acid (5-ASA). The 5-ASA component acts locally in the intestinal mucosa to reduce inflammation by inhibiting prostaglandin synthesis and scavenging free radicals. Sulfapyridine is absorbed systemically and contributes anti-inflammatory and immunomodulatory effects, including inhibition of T-cell proliferation and cytokine production. The exact mechanism in rheumatoid arthritis is not fully understood but likely involves immunomodulation and suppression of inflammatory pathways.
Mechanism Steps
💡 How to Take salday 1000mg tablet
Strength: Delayed-release tablet, 1000 mg
Dosage Information
| Adult Dosage | The usual adult dose for rheumatoid arthritis is 500 mg to 1000 mg (as delayed-release tablets) two to three times daily, gradually increased as tolerated. For ulcerative colitis, the initial dose is 500 mg two to four times daily, then maintenance 500 mg four times daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor closely for side effects. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Monitor kidney function closely. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Monitor liver function closely. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 4000 mg (4 grams) for adults, but individual dosing must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of salday 1000mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Digoxin | Major | |
| Rifampicin | Moderate | |
| Thiazide diuretics | Moderate | |
| Oral hypoglycemics | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Digoxin
- Rifampicin
⚡ Moderate Interactions
- Folic acid antagonists (e.g., methotrexate)
- Thiazide diuretics
- Oral hypoglycemics
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of liver damage and stomach bleeding, and may worsen side effects like dizziness and nausea.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to sulfasalazine, sulfonamides, or salicylates","Porphyria","Intestinal or urinary obstruction","Severe liver disease","Severe kidney disease","Children under 2 years of age","Pregnancy at term or during lactation (relative)"]
⚠️ Warnings & Precautions
["Serious blood disorders: Agranulocytosis, aplastic anemia, and hemolytic anemia can occur. Monitor blood counts regularly.","Hepatotoxicity: Liver damage can occur. Monitor liver enzymes.","Severe skin reactions: Stevens-Johnson syndrome and toxic epidermal necrolysis have been reported. Discontinue at first sign of rash.","Hypersensitivity reactions: May cause fever, rash, and eosinophilia. Discontinue if suspected.","Renal effects: Crystalluria and nephritis may occur. Maintain hydration.","Folate deficiency: Sulfasalazine can impair folate absorption. Consider supplementation.","Delayed-release tablets: Do not crush or chew; swallow whole.","Use in elderly: Increased risk of side effects; monitor closely."]
🤱 Lactation Safety
Sulfasalazine is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but monitor the infant for diarrhea or rash. Consult your doctor before use.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, and drowsiness. Seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor blood counts, liver and kidney function. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a full glass of water; do not crush or chew. Take with food to reduce stomach upset. Drink plenty of fluids during treatment. Avoid alcohol while taking this medicine as it may increase liver risk. Do not start or stop any new medicine without consulting your doctor. Keep all follow-up appointments for blood tests to monitor your blood counts, liver, and kidney function. If you miss a dose, take it as soon as you remember unless it is almost time for your next dose; do not double dose. Store at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to side effects. Start with a lower dose and monitor closely for blood, liver, and kidney function.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before starting or continuing this medicine. It is generally considered safe but requires monitoring.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine. It may need to be temporarily stopped before surgery due to bleeding risk. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist about this medicine. It may increase bleeding risk during dental procedures. Your dentist may recommend temporary discontinuation.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is encouraged, but avoid high-impact activities during flare-ups. Listen to your body and rest when needed. Consult a physiotherapist for personalized guidance.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. Take regular breaks and manage stress.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately. Your doctor may adjust or stop the medicine based on your condition and test results.
📅 Long-Term Use Effects
Long-term use requires regular monitoring of blood counts, liver, and kidney function. It may cause folate deficiency; supplementation may be needed. Periodic eye exams are recommended. Do not stop without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and joint mobility.
Evidence: Well-establishedAnti-inflammatory diet may help manage symptoms.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may affect your immune response. Consult your doctor before receiving any live vaccines. Inactivated vaccines are generally safe.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep enough supply for your trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: It may take 6-12 weeks to see full therapeutic effects for rheumatoid arthritis, and a few weeks for ulcerative colitis.
A: Some medicines can interact. Always inform your doctor about all medicines you take.
A: Consult your doctor. It is generally considered safe but risks and benefits must be weighed.
🤔 Common Patient Concerns
🔄 Substitutes for salday 1000mg tablet
View AllAlternative brands with exact same active ingredient:
-
DavaIndia Sulfasalazine 1000mg TabletDavaindia Generic Pharmacy ₹59.50 56.2% CHEAPER
-
SFZ DS 1000mg TabletTBG pharma ltd ₹97.84 28% CHEAPER
-
sulseas ds 1000mg tabletOverseas Healthcare Pvt Ltd ₹108.28 20.3% CHEAPER
-
Salazar DS Tablet DRZydus Cadila ₹122.31 10% CHEAPER
-
ssn - ds tablet drRhumasafe Pharmaceutical ₹135.00 0.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine works immediately.
Fact: It may take several weeks to months to see full effects. - Myth: It is safe to stop without doctor's advice.
Fact: Stopping suddenly can worsen your condition. Always consult your doctor. - Myth: It can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach upset.
🔄 Alternative Options
Generic Alternatives
- Sulfasalazine delayed-release tablets
Brand Alternatives
- Saaz-DS Tablet DR
- Saaz Tablet
- Sulfasalazine Tablets