Axifur 250mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing.
- Severe or bloody diarrhoea, which may occur during or after treatment.
- Yellowing of skin or eyes, dark urine, or severe abdominal pain.
- Painful rash with blisters or peeling skin, or sores in the mouth.
- Decreased urine output, swelling, or extreme fatigue.
- Seizures or confusion, especially in patients with kidney disease.
If experiencing severe symptoms, call emergency services immediately.
What is Rokz 250mg Tablet used for?
This medicine is an antibiotic containing cefuroxime 250 mg. It is used to treat bacterial infections of the respiratory tract, urinary tract, skin, and soft tissues. It works by killing bacteria. Take it with food, twice daily, and complete the full course as prescribed.
- Generic Name: Cefuroxime (250mg)
- Manufacturer: Eclipser Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Rokz 250mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक है जिसमें सेफ्यूरोक्सिम 250 मिलीग्राम होता है। यह श्वसन तंत्र, मूत्र मार्ग, त्वचा और कोमल ऊतकों के बैक्टीरियल संक्रमण के इलाज के लिए इस्तेमाल की जाती है। यह बैक्टीरिया को मारकर काम करती है। इसे भोजन के साथ लें और डॉक्टर के बताए अनुसार पूरा कोर्स करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, मतली, पेट दर्द, सिरदर्द और हल्के दाने शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी, गंभीर दस्त और लीवर की समस्या शामिल हो सकती है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। पर्याप्त पानी पिएं। इस दवा के साथ शराब न लें। अगर आपको किडनी या लीवर की समस्या है या एंटीबायोटिक से एलर्जी है तो डॉक्टर को बताएं। दवा को बच्चों से दूर रखें।
💊 Rokz 250mg Tablet Uses & Benefits
[{"condition":"Respiratory tract infections","description":"Used to treat infections of the throat, sinuses, ears, and lungs caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against many bacteria that cause bladder and kidney infections.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for infections such as cellulitis, abscesses, and wound infections.","evidence":"Well-established"},{"condition":"Gonorrhoea","description":"Used as part of treatment for uncomplicated gonorrhoea caused by susceptible strains.","evidence":"Well-established"},{"condition":"Surgical prophylaxis","description":"Given before certain surgeries to prevent postoperative infections.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used off-label for early Lyme disease in patients who cannot take doxycycline.","evidence":"Limited"},{"condition":"Traveler's diarrhoea","description":"Occasionally prescribed off-label for severe traveler's diarrhoea caused by susceptible bacteria.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Skin infections, Gonorrhoea, Surgical prophylaxis
📋 Drug Information
| Generic Name(s) | Cefuroxime (250mg) |
| Brand Name | Rokz 250mg Tablet |
| Manufacturer | Eclipser Pharmaceuticals |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture, heat, and direct sunlight. Keep in the original container. |
| Shelf Life | Typically 2 years from the date of manufacture. Check the expiry date on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to specific proteins called penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding blocks the final step of cell wall synthesis, leading to a weakened cell wall and eventually causing the bacteria to burst and die. It is bactericidal, meaning it kills bacteria directly.
Mechanism Steps
💡 How to Take Rokz 250mg Tablet
Strength: This medicine is available as a 250 mg immediate-release tablet for oral administration.
Dosage Information
| Adult Dosage | The usual adult dose for most infections is 250 mg to 500 mg taken twice daily, depending on the type and severity of the infection. For uncomplicated urinary tract infections, a dose of 125 mg to 250 mg twice daily may be used. For gonorrhoea, a single dose of 1 g is often given. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced kidney function, so dose adjustment may be necessary. Your doctor will determine the appropriate dose based on your kidney function. |
| Renal Impairment | In patients with kidney impairment, the dose and/or frequency may need to be reduced. For creatinine clearance between 10 and 20 mL/min, the usual dose may be given every 24 hours. For creatinine clearance less than 10 mL/min, the usual dose may be given every 48 hours. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is required for liver impairment, as this medicine is not significantly metabolized by the liver. However, use with caution in patients with both liver and kidney disease. |
| Maximum Daily Dose | The maximum recommended adult dose is 1 g per day for most infections, but up to 1.5 g per day may be used for severe infections. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Rokz 250mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Probenecid | Major | |
| Loop diuretics | Major | |
| Oral contraceptives | Moderate | |
| Antacids | Moderate | |
| H2 blockers | Moderate | |
| Aminoglycosides | Moderate | |
| Alcohol | Minor |
🚨 Major Interactions
- Warfarin
- Probenecid
- Loop diuretics (e.g., furosemide)
⚡ Moderate Interactions
- Oral contraceptives
- Antacids and H2 blockers
- Aminoglycosides
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach upset, dizziness, and drowsiness. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefuroxime or other cephalosporins","Severe allergy to penicillins (cross-reactivity possible)","Previous history of severe allergic reaction to any beta-lactam antibiotic"]
⚠️ Warnings & Precautions
["Use with caution in patients with kidney disease; dose adjustment may be required.","Use with caution in patients with a history of colitis.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","Do not use for viral infections; it is ineffective and may promote resistance.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to monitor for potential effects on the baby, such as diarrhoea or thrush.
💊 Overdose Management
Overdose may cause nausea, vomiting, stomach pain, and diarrhoea. In severe cases, seizures and encephalopathy can occur, especially in patients with kidney impairment. Treatment is supportive and symptomatic. Contact a poison control center or emergency room immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early. Take it with food to reduce stomach upset. Drink plenty of water. Avoid alcohol while taking this medicine. Inform your doctor if you have kidney problems, liver problems, or a history of allergies to antibiotics. Do not share this medicine with others. Keep it out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and are more prone to side effects. Dose adjustment may be necessary. Monitor for signs of superinfection and kidney problems.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe, but only use if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be used before or after surgery to prevent infection. Follow your surgeon's instructions carefully. Inform your surgeon if you have any allergies or kidney problems.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may be used prophylactically before dental procedures in patients at risk of infective endocarditis.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
You can continue light exercise if you feel well, but avoid strenuous activity if you have fever or fatigue. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities, but take rest if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to antibiotic resistance and superinfections. Regular monitoring of kidney and liver function may be needed if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection and susceptibility, other antibiotics like amoxicillin or azithromycin may be used.
Evidence: Well-establishedRest, hydration, and symptomatic treatment can complement antibiotic therapy.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for a live vaccine, inform your doctor, as antibiotics may affect the vaccine's effectiveness in some cases.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and heat. If traveling across time zones, adjust dosing times gradually under medical guidance. Check customs regulations for carrying antibiotics. Keep it in your carry-on luggage to avoid loss.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2 to 3 days, but it is important to complete the full course as prescribed.
A: Yes, taking it with food increases absorption and reduces stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: It is generally considered safe during pregnancy when prescribed by a doctor. However, consult your doctor before taking any medicine during pregnancy.
A: It is best to avoid alcohol as it may worsen side effects like dizziness and stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for Rokz 250mg Tablet
View AllAlternative brands with exact same active ingredient:
-
wezcef 250mg tabletWezen Chemicals Pvt Ltd ₹18.75 9.1% CHEAPER
-
xime 250mg syrupPCI Pharmaceuticals ₹22.38 8.5% COSTLIER
-
wyceft 250mg tabletVostok & Wilcure Remedies ₹24.38 18.2% COSTLIER
-
Roxef 250mg InjectionReco Drugs ₹25.00 21.2% COSTLIER
-
jectocef 250mg injectionTrident Pharma ₹26.63 29.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections. It does not treat viral infections. - Myth: You can stop taking the antibiotic once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to reduce antibiotic resistance. - Myth: Antibiotics weaken the immune system.
Fact: Antibiotics do not weaken the immune system; they target bacteria. However, they can disrupt healthy gut bacteria, which may have temporary effects.
🔄 Alternative Options
Generic Alternatives
- Cefuroxime 250 mg tablet
Brand Alternatives
- Axifur 250mg tablet