Augtaz 250mg/31.25mg Injection: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or wheezing
- Swelling of the face, lips, tongue, or throat
- Severe or bloody diarrhea
- Rash with blisters or peeling skin
- Yellowing of the skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is Ritecef T 250 mg/31.25 mg Injection used for?
This medicine is a combination antibiotic injection containing ceftriaxone and tazobactum. It is used to treat serious bacterial infections, including those resistant to other antibiotics. It works by killing bacteria and preventing their growth. It must be given by a healthcare professional.
- Generic Name: Ceftriaxone (250mg) + Tazobactum (31.25mg)
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Ritecef T 250 mg/31.25 mg Injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्ट्रिएक्सोन और टैज़ोबैक्टम का संयोजन है, जिसे इंजेक्शन के रूप में दिया जाता है। यह गंभीर बैक्टीरियल संक्रमणों के इलाज के लिए उपयोग की जाती है, जैसे कि मूत्र मार्ग का संक्रमण, पेट के अंदर का संक्रमण, त्वचा का संक्रमण, और निमोनिया। यह दवा बैक्टीरिया को मारती है और उनके विकास को रोकती है। यह केवल डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। वायरल संक्रमण जैसे सर्दी-जुकाम के लिए यह दवा प्रभावी नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, लालिमा, दस्त, जी मिचलाना, उल्टी, सिरदर्द और हल्के दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर त्वचा प्रतिक्रिया, और आंतों का गंभीर संक्रमण हो सकता है। यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर दस्त हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में प्रशिक्षित स्वास्थ्य कर्मी द्वारा ही दी जानी चाहिए। इससे पहले कि आपको यह दवा दी जाए, अपने डॉक्टर को पेनिसिलिन या सेफलोस्पोरिन से एलर्जी के बारे में बताएं। यदि आप गर्भवती हैं या स्तनपान करा रही हैं, तो डॉक्टर को सूचित करें। इलाज के दौरान शराब न पिएं। पूरा कोर्स पूरा करें, बीच में न रोकें। कोई भी नया लक्षण दिखने पर डॉक्टर को बताएं।
💊 Ritecef T 250 mg/31.25 mg Injection Uses & Benefits
[{"condition":"Complicated urinary tract infections","description":"Used to treat kidney and bladder infections caused by beta-lactamase-producing bacteria when oral therapy is not suitable.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Effective against mixed aerobic and anaerobic bacteria in conditions such as peritonitis and intra-abdominal abscess.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats severe cellulitis, abscesses, and wound infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Community-acquired pneumonia","description":"Used in hospitalized patients when resistant or beta-lactamase-producing pathogens are suspected.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Ceftriaxone is a standard treatment for meningitis caused by susceptible bacteria, and tazobactum extends coverage against some resistant strains.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"Ceftriaxone is a first-line treatment for uncomplicated gonorrhea, though the combination with tazobactum is not routinely used for this indication.","evidence":"Well-established for ceftriaxone alone"}]
Off-label uses: [{"condition":"Prophylaxis in certain surgical procedures","description":"Sometimes used off-label for surgical prophylaxis when standard agents are not suitable, but this is not a routine approved use.","evidence":"Limited"},{"condition":"Lyme disease with neurological involvement","description":"Ceftriaxone is used off-label for late Lyme disease, but the combination with tazobactum is not standard.","evidence":"Limited"}]
Primary treatment for: Bacterial infections caused by susceptible organisms
Also treats: Complicated urinary tract infections, Intra-abdominal infections, Skin and soft tissue infections, Community-acquired pneumonia, Bacterial meningitis
📋 Drug Information
| Generic Name(s) | Ceftriaxone (250mg) + Tazobactum (31.25mg) |
| Brand Name | Ritecef T 250 mg/31.25 mg Injection |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | vial of 1 Injection (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Parenteral (intravenous or intramuscular). Intravenous administration is preferred for serious infections. Intramuscular injection may be used for less severe infections. The injection must be prepared and administered by a qualified healthcare professional |
| Storage | Store the unreconstituted powder at room temperature between 20°C and 25°C (68°F to 77°F). Protect from light and moisture. After reconstitution, the solution should be used immediately or stored as directed by the manufacturer. Do not freeze. Keep out of reach of children. |
| Shelf Life | The shelf life of the unreconstituted powder is typically 24 months from the date of manufacture. Check the expiry date on the packaging. Once reconstituted, use within the time specified by the manufacturer, usually within 6 hours at room temperature or 24 hours if refrigerated. |
| WHO Guideline | Not established from the available information for this specific combination product. Guidelines for ceftriaxone alone exist for various infections, but the combination with tazobactum is not specifically addressed in WHO guidelines. |
| ICMR Guideline | Not established from the available information for this specific combination product. ICMR guidelines may recommend ceftriaxone for certain infections, but the combination with tazobactum is not specifically mentioned. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting bacterial cell wall synthesis. Ceftriaxone binds to penicillin-binding proteins, which are enzymes involved in cross-linking the peptidoglycan layer of the bacterial cell wall. This binding prevents the final step of cell wall construction, leading to bacterial cell lysis and death. Tazobactum is a beta-lactamase inhibitor that irreversibly binds to certain beta-lactamase enzymes produced by bacteria, protecting ceftriaxone from enzymatic destruction. This combination extends the antibacterial spectrum of ceftriaxone to include some beta-lactamase-producing strains.
Mechanism Steps
💡 How to Take Ritecef T 250 mg/31.25 mg Injection
Strength: Each vial contains ceftriaxone 250 mg and tazobactum 31.25 mg as a sterile powder for injection.
Dosage Information
| Adult Dosage | The adult dose of this medicine is individualized by a qualified clinician based on the type and severity of infection, the patient's renal and hepatic function, and the susceptibility of the causative organism. A typical adult dose for serious infections may be 1-2 grams of ceftriaxone with the corresponding tazobactum component every 12-24 hours, but the exact dose and frequency must be determined by the treating doctor. This product contains 250 mg ceftriaxone and 31.25 mg tazobactum per vial, so multiple vials may be required to achieve the prescribed dose. Do not self-administer. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific combination product. Consult a pediatrician. Doses are typically weight-based and must be determined by a qualified pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. The dose must be individualized by a qualified clinician based on renal function and clinical response. Monitor kidney function closely. |
| Renal Impairment | In patients with renal impairment, dose adjustment may be necessary. Ceftriaxone does not usually require adjustment in mild to moderate renal impairment, but tazobactum may accumulate. For severe renal impairment (creatinine clearance less than 30 mL/min), the dose may need to be reduced or the interval extended. Consult a clinician for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, ceftriaxone elimination may be prolonged. Dose adjustment may be required. Monitor liver function tests. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose of ceftriaxone is generally 4 grams per day, but the exact maximum for this combination product must be determined by a qualified clinician based on the patient's condition. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Ritecef T 250 mg/31.25 mg Injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Calcium-containing IV solutions | Major | |
| Warfarin | Major | |
| Aminoglycosides | Major | |
| Loop diuretics | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Calcium-containing intravenous solutions
- Warfarin
- Aminoglycosides (e.g., gentamicin)
⚡ Moderate Interactions
- Loop diuretics (e.g., furosemide)
- Probenecid
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine because it may increase the risk of liver side effects and drowsiness. There is no specific disulfiram-like reaction reported, but caution is advised.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to ceftriaxone, tazobactum, or other beta-lactam antibiotics","History of anaphylaxis to penicillins or cephalosporins","Neonates (28 days or younger) requiring calcium-containing IV solutions","Hyperbilirubinemic neonates","Concomitant use with calcium-containing IV solutions in neonates"]
⚠️ Warnings & Precautions
["Serious and occasionally fatal hypersensitivity reactions can occur. Discontinue immediately if allergic reaction is suspected.","Clostridioides difficile-associated diarrhea may occur; monitor for severe diarrhea.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","May cause gallbladder sludge or pseudolithiasis, which is usually reversible after discontinuation.","Blood counts should be monitored during prolonged therapy.","Use with caution in patients with renal or hepatic impairment; dose adjustment may be needed.","Do not mix with calcium-containing solutions or other drugs in the same IV line."]
🤱 Lactation Safety
Ceftriaxone is excreted in human breast milk in low concentrations and is generally considered compatible with breastfeeding. Tazobactum data are limited. Consult your doctor before breastfeeding while receiving this medicine.
💊 Overdose Management
Overdose of this medicine is unlikely due to its parenteral administration by healthcare professionals. In case of accidental overdose, treatment should be symptomatic and supportive. Ceftriaxone is not removed by hemodialysis or peritoneal dialysis. Tazobactum may be removed by hemodialysis. Monitor vital signs and provide supportive care.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If you miss an appointment for your injection, contact your doctor as soon as possible to reschedule. Do not attempt to self-administer. If a dose is missed, your doctor will determine the best time for the next dose based on your treatment schedule.
Additional Safety Advice
This medicine must only be given by a trained healthcare professional in a setting where emergency equipment is available. Before the first dose, tell your doctor about any allergy to penicillin, cephalosporins, or other antibiotics. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. Do not stop or change the dose on your own, even if you feel better, because incomplete treatment can lead to resistant bacteria. Avoid alcohol during treatment as it may worsen liver stress and increase drowsiness. Drink plenty of fluids unless your doctor has restricted fluids. Report any new symptoms such as severe diarrhea, rash, or difficulty breathing without delay. Keep all follow-up appointments for blood tests and clinical review.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney and liver function, which can affect how this medicine is cleared from the body. Dose adjustments may be necessary. Monitor for signs of toxicity and ensure adequate hydration.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss with your doctor before receiving this medicine. Ceftriaxone is generally considered safe in pregnancy when needed, but tazobactum data are limited. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
This medicine may be used to treat or prevent infections after surgery. If you have recently had surgery, inform your surgeon and anesthesiologist about all medicines you are taking. Follow your surgeon's instructions for wound care and follow-up.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine. Antibiotics may be needed before dental procedures if you have certain heart conditions. Your dentist will coordinate with your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may feel tired or weak. Avoid strenuous exercise until you have recovered. Light activity such as walking is fine if you feel up to it. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
You may need to take time off work or school while receiving this medicine, especially if you are hospitalized. You should not drive or operate heavy machinery if you feel dizzy, drowsy, or unwell. Ask your doctor when you can safely resume normal activities.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your clinical response and test results. If you experience severe side effects, contact your doctor immediately; they will determine whether to stop or change the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is not common because it is usually given for a short course. Prolonged use may increase the risk of antibiotic resistance, fungal infections, and blood disorders. Regular monitoring of blood counts, liver, and kidney function is advised for extended therapy. If you need long-term treatment, your doctor will monitor you closely.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For less severe infections, oral antibiotics may be used instead of injections.
Evidence: Well-establishedDepending on the bacteria and resistance patterns, other antibiotics may be appropriate.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, live vaccines should be avoided during acute infection. Consult your doctor about vaccination timing.
📦 Storage Guide
✅ DO
Store the unreconstituted powder at room temperature (20-25°C).
❌ DON'T
Do not freeze the powder or the reconstituted solution.
✅ DO
Keep the vial in its original carton to protect from light.
❌ DON'T
Do not store in the bathroom or near a sink.
✅ DO
Use the reconstituted solution within the time specified by the manufacturer.
❌ DON'T
Do not use if the solution is cloudy or contains particles.
✈️ Traveling with This Medicine
This medicine is given by a healthcare professional, so travel with it is not typical. If you are traveling and need to continue treatment, ensure you have a copy of your prescription and a letter from your doctor explaining the need for injectable antibiotics. Carry the medicine in its original packaging and keep it at the recommended temperature. Check customs regulations for carrying injectable medicines. Plan your doses around travel schedules with your doctor's guidance.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours after the first dose, but it is important to complete the full course as prescribed.
A: No, this medicine must be given by a healthcare professional in a clinic or hospital setting.
A: Tell your doctor before receiving this medicine. If you have a severe allergy, this medicine may not be suitable for you.
A: The safety and effectiveness in children depend on the specific infection and the child's weight. Only a pediatrician can decide if it is appropriate.
🤔 Common Patient Concerns
🔄 Substitutes for Ritecef T 250 mg/31.25 mg Injection
View AllAlternative brands with exact same active ingredient:
-
Twinlet 250 mg/31.25 mg InjectionMedopharm ₹31.55 45.7% CHEAPER
-
maxceft ct 250 mg/31.25 mg injectionAlembic Pharmaceuticals Ltd ₹35.16 39.5% CHEAPER
-
zenoxim xp kid 250mg/31.25mg injectionIndchemie Health Specialities Pvt Ltd ₹38.91 33.1% CHEAPER
-
Symtaz P 250 mg/31.25 mg InjectionSymbiotic Drugs ₹39.66 31.8% CHEAPER
-
agicef t 250mg/31.25mg injectionAegle Healthcare ₹40.00 31.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and only works against bacterial infections. It is ineffective against viruses. - Myth: You can stop the injection once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe for everyone.
Fact: It is not safe for people with a severe allergy to beta-lactam antibiotics and should be used with caution in certain populations.
🔄 Alternative Options
Generic Alternatives
- Ceftriaxone and tazobactum injection (generic versions may be available)
Brand Alternatives
- Augtaz 250mg/31.25mg injection