Bispec 5 Tablet (Solifenacin 5 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Inability to urinate or severe lower abdominal pain
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Severe constipation with abdominal pain and vomiting
- Rash, itching, or hives all over the body
- Irregular heartbeat, fainting, or seizures
- Yellowing of the skin or eyes (jaundice)
- Severe dizziness or blurred vision that does not go away
If experiencing severe symptoms, call emergency services immediately.
What is restream 5 tablet used for?
This medicine contains Solifenacin 5 mg, an antimuscarinic agent used to treat overactive bladder. It works by relaxing the bladder muscle, reducing urgency, frequency, and urge incontinence. It is taken once daily, with or without food, and should be used under medical supervision.
- Generic Name: Solifenacin (5mg)
- Manufacturer: Tas Med India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 restream 5 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सोलिफेनासिन 5 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग ओवरएक्टिव ब्लैडर (अत्यधिक सक्रिय मूत्राशय) के इलाज के लिए किया जाता है। यह मूत्राशय की मांसपेशियों को आराम देकर बार-बार पेशाब आने की इच्छा, अचानक पेशाब आने की तीव्रता और पेशाब रोक न पाने की समस्या को कम करती है। यह दवा मूत्राशय की क्षमता को बढ़ाती है और दिन-रात में पेशाब आने की संख्या को कम करती है। यह केवल डॉक्टर के पर्चे पर ही मिलती है और डॉक्टर के निर्देशानुसार ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, कब्ज, धुंधली दृष्टि और अपच शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी पेशाब रुकने की समस्या, गंभीर कब्ज, चक्कर आना और नींद आना भी हो सकता है। दुर्लभ मामलों में चेहरे, होंठ, जीभ या गले में सूजन, सांस लेने में कठिनाई या एलर्जी की प्रतिक्रिया हो सकती है। यदि कोई भी दुष्प्रभाव गंभीर हो या लंबे समय तक बना रहे, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर यदि आपको पेशाब रुकने, पेट में रुकावट, ग्लूकोमा, गुर्दे या यकृत की बीमारी है। यह दवा नींद और धुंधली दृष्टि का कारण बन सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें जब तक कि आपको इसका असर पता न चल जाए। इस दवा के साथ शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। दवा को पानी के साथ पूरा निगलें, चबाएं नहीं। यदि आपको कोई खुराक छूट जाए तो याद आते ही ले लें, लेकिन अगली खुराक का समय नजदीक हो तो छूटी हुई खुराक छोड़ दें। दो खुराक एक साथ न लें। इस दवा को कमरे के तापमान पर, नमी और गर्मी से दूर रखें।
💊 restream 5 tablet Uses & Benefits
[{"condition":"Overactive bladder with urge urinary incontinence","description":"This medicine reduces episodes of urge incontinence and helps control the sudden, strong urge to urinate.","evidence":"Well-established"},{"condition":"Overactive bladder with urgency and frequency","description":"This medicine decreases the number of times you need to urinate during the day and night and reduces the feeling of urgency.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Neurogenic detrusor overactivity","description":"Sometimes prescribed off-label for bladder control in patients with neurological conditions such as spinal cord injury or multiple sclerosis.","evidence":"Limited"},{"condition":"Nocturia","description":"May be used off-label to reduce nighttime urination in some patients, but evidence is not strong.","evidence":"Limited"}]
Primary treatment for: Overactive bladder
Also treats: Urge urinary incontinence, Urinary frequency, Urinary urgency
📋 Drug Information
| Generic Name(s) | Solifenacin (5mg) |
| Brand Name | restream 5 tablet |
| Manufacturer | Tas Med India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | UROLOGY |
| Action Class | Selective M3 anticholinergic (Bladder) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in their original container, tightly closed, away from moisture and heat. Do not refrigerate. Keep out of reach of children. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture. Refer to the packaging for the exact expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a competitive muscarinic receptor antagonist. It works by blocking the action of acetylcholine at muscarinic receptors in the detrusor muscle of the bladder. This blockade reduces involuntary contractions of the bladder, thereby increasing bladder capacity and decreasing the urge to urinate. It has some selectivity for the M3 subtype of muscarinic receptors, which are primarily responsible for bladder contractions, but it can also affect other muscarinic receptors, leading to side effects such as dry mouth and constipation.
Mechanism Steps
💡 How to Take restream 5 tablet
Strength: Immediate-release tablet containing 5 mg of Solifenacin.
Dosage Information
| Adult Dosage | The recommended dose of this medicine for adults is 5 mg once daily. If tolerated, the dose may be increased to 10 mg once daily after 4 to 8 weeks, based on clinical response. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. For patients with moderate hepatic impairment or severe renal impairment, the dose should not exceed 5 mg once daily. This medicine can be taken with or without food. Swallow the tablet whole with water. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No dose adjustment is required for elderly patients based solely on age. However, elderly patients may be more sensitive to the anticholinergic effects of this medicine, such as dry mouth, constipation, and urinary retention. Use with caution and monitor closely. |
| Renal Impairment | For patients with severe renal impairment (creatinine clearance <30 mL/min), the dose should not exceed 5 mg once daily. No dose adjustment is needed for mild to moderate renal impairment. |
| Hepatic Impairment | For patients with moderate hepatic impairment (Child-Pugh B), the dose should not exceed 5 mg once daily. This medicine is not recommended in patients with severe hepatic impairment (Child-Pugh C). |
| Maximum Daily Dose | The maximum recommended daily dose is 10 mg once daily, except in patients with moderate hepatic impairment or severe renal impairment, where the maximum dose is 5 mg once daily. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of restream 5 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Itraconazole | Major | |
| Ritonavir | Major | |
| Oxybutynin | Moderate | |
| Tolterodine | Moderate | |
| Erythromycin | Moderate | |
| Verapamil | Moderate | |
| Warfarin | Minor | |
| Metformin | Minor | |
| Grapefruit juice | Moderate |
🚨 Major Interactions
- Ketoconazole
- Itraconazole
- Ritonavir
⚡ Moderate Interactions
- Other anticholinergic drugs (e.g., oxybutynin, tolterodine, tricyclic antidepressants, antihistamines)
- Erythromycin
- Verapamil
🍷 Alcohol Interaction
Alcohol may increase the drowsiness and dizziness caused by this medicine. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Urinary retention","Gastric retention","Uncontrolled narrow-angle glaucoma","Known hypersensitivity to solifenacin or any component of the formulation","Severe hepatic impairment (Child-Pugh C)","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["This medicine may cause urinary retention. Use with caution in patients with bladder outlet obstruction.","This medicine may cause gastric retention. Use with caution in patients with gastrointestinal obstructive disorders.","This medicine may increase intraocular pressure. Use with caution in patients with narrow-angle glaucoma.","This medicine may cause drowsiness and blurred vision. Patients should avoid driving or operating machinery until they know how it affects them.","This medicine may cause QT prolongation. Use with caution in patients with a history of QT prolongation or risk factors.","This medicine should be used with caution in patients with moderate hepatic impairment (dose not to exceed 5 mg daily) and severe renal impairment (dose not to exceed 5 mg daily).","This medicine may cause angioedema. If angioedema occurs, discontinue the medicine and seek immediate medical attention.","This medicine may cause constipation. Monitor and manage appropriately, especially in elderly patients."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose with this medicine can cause severe anticholinergic effects such as dry mouth, constipation, urinary retention, blurred vision, tachycardia, and possibly seizures. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Gastric lavage may be considered if the overdose is recent. There is no specific antidote. Patients should be monitored for signs of anticholinergic toxicity.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Before taking this medicine, tell your doctor if you have any of the following conditions: urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, kidney disease, liver disease, or a history of long QT syndrome. This medicine may cause drowsiness or blurred vision, so avoid driving or operating machinery until you know how it affects you. Do not drink alcohol while taking this medicine because it can increase drowsiness. Take this medicine with water and swallow the tablet whole; do not crush or chew it. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time. Keep all your medical appointments and inform your doctor about all other medicines, supplements, or herbal products you are using. This medicine is not recommended during pregnancy or breastfeeding unless clearly needed and advised by your doctor. Store this medicine at room temperature, away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) may be more sensitive to the anticholinergic effects of this medicine, such as dry mouth, constipation, urinary retention, and confusion. Use with caution and monitor closely. The dose should not exceed 5 mg once daily in patients with moderate hepatic impairment or severe renal impairment. Regular follow-up is recommended to assess efficacy and tolerability.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. This medicine should be used during pregnancy only if clearly needed. Your doctor will weigh the benefits and risks. If you become pregnant while taking this medicine, inform your doctor immediately.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and other medications used during surgery. Your doctor may advise you to stop the medicine temporarily before surgery. Follow your doctor's instructions carefully.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine can cause dry mouth, which may increase the risk of dental caries and gum disease. Your dentist may recommend preventive measures. It may also interact with medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness or blurred vision, which can affect your ability to exercise safely. Avoid activities that require sharp vision or coordination, such as cycling outdoors or using heavy gym equipment, until you know how the medicine affects you. Gentle exercises like walking, swimming, and yoga are generally safe. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, blurred vision, and dizziness, which can affect your ability to drive, operate machinery, or perform tasks requiring alertness. Avoid these activities until you know how the medicine affects you. It may also cause dry mouth, which can be managed with water and sugar-free gum. Most patients can continue their normal work and daily activities with some adjustments. Inform your employer if your job involves operating heavy machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects such as urinary retention, angioedema, or severe constipation, stop the medicine and seek immediate medical attention. Your doctor may adjust the dose or switch to a different medication if needed. If you wish to discontinue, your doctor will guide you on how to stop safely.
📅 Long-Term Use Effects
Long-term use of this medicine is generally well tolerated. However, prolonged use may increase the risk of dental problems due to dry mouth, and constipation may become chronic. Regular monitoring of urinary symptoms, renal and hepatic function, and anticholinergic side effects is recommended. Some patients may develop tolerance, and dose adjustment may be needed. Periodic review with your doctor is advised to assess the continued need for therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Scheduled voiding and delaying urination to increase bladder capacity.
Evidence: Well-establishedKegel exercises to strengthen the muscles that control urination.
Evidence: Well-establishedA technique to help you gain control over bladder muscles.
Evidence: ModerateMild electrical pulses to stimulate pelvic floor muscles.
Evidence: ModerateAvoiding bladder irritants like caffeine, alcohol, and spicy foods.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, if you are feeling unwell or have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom cabinet.
✅ DO
Keep out of reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in your carry-on luggage to avoid loss or temperature extremes. If crossing time zones, continue taking your dose at the same interval as prescribed; you may need to adjust the timing gradually. Keep the medicine away from direct sunlight and moisture. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some patients may notice improvement within one week, but full therapeutic effect may take 4 to 6 weeks. Continue taking it as prescribed and follow up with your doctor.
A: Yes, you can take it at any time of day, but it is best to take it at the same time each day. Some patients prefer taking it in the morning to minimize nighttime urination, but follow your doctor's advice.
A: Dry mouth is a common side effect. Sip water frequently, chew sugar-free gum, or use a saliva substitute. If it becomes severe or bothersome, consult your doctor.
A: Do not stop taking this medicine without consulting your doctor. Symptoms may return if you stop abruptly. Your doctor will advise you on the appropriate duration of treatment.
A: Elderly patients may be more sensitive to the side effects of this medicine, such as dry mouth, constipation, and urinary retention. Use with caution and under medical supervision.
🤔 Common Patient Concerns
🔄 Substitutes for restream 5 tablet
View AllAlternative brands with exact same active ingredient:
-
stayhappi solifenacin 5mg tabletSarvagunaushdhi Pvt Ltd ₹93.75 47.1% CHEAPER
-
urislow 5mg tabletLividus Pharmaceuticals Pvt Ltd ₹154.69 12.7% CHEAPER
-
soliguard 5 mg tabletEmcure Pharmaceuticals Ltd ₹178.13 0.5% COSTLIER
-
samlifen 5mg tabletSamarth Life Sciences Pvt Ltd ₹182.47 3% COSTLIER
-
solinyx tabletIgnyx Pharmaceuticals ₹187.50 5.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure overactive bladder permanently.
Fact: This medicine helps manage symptoms but does not cure the underlying condition. It must be taken regularly to control symptoms. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine is a prescription-only medication and should only be taken under the supervision of a qualified clinician. - Myth: You can stop taking this medicine whenever you feel better.
Fact: You should not stop taking this medicine without consulting your doctor, as symptoms may return. Your doctor will advise you on the appropriate duration of treatment.
🔄 Alternative Options
Generic Alternatives
- Solifenacin succinate 5 mg tablet
Brand Alternatives
- Bispec 5 Tablet
- Vesicare 5 mg Tablet
- Solifen 5 mg Tablet