reskon dmr syrup - Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml) medicine

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🏭 Parul Health Care Private Limited 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Well-established for allergic rhinitis and common cold.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction (rash, swelling, difficulty breathing)
  • Irregular heartbeat or palpitations
  • Seizures
  • Severe drowsiness or confusion
  • Blood in vomit or stool
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is reskon dmr syrup used for?

This medicine is a combination of phenylephrine and chlorpheniramine maleate used to relieve nasal congestion, sneezing, and runny nose due to allergies or colds. It works by constricting nasal blood vessels and blocking histamine.

  • Generic Name: Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml)
  • Manufacturer: Parul Health Care Private Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 reskon dmr syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी-जुकाम से होने वाली नाक बंद, छींक, बहती नाक और आंखों में खुजली जैसी समस्याओं में राहत देती है। इसमें फेनिलएफ्रिन नाक की रक्त वाहिकाओं को सिकोड़कर जमाव कम करता है, और क्लोरफेनिरामाइन हिस्टामिन को रोककर एलर्जी के लक्षणों को कम करता है। यह दवा आमतौर पर वयस्कों और बड़े बच्चों के लिए है, लेकिन डॉक्टर की सलाह के बिना न दें।

साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि और पेट खराब होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, दिल की धड़कन अनियमित होना, दौरे पड़ना आदि हो सकते हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या पेशाब में कठिनाई की जानकारी दें। इस दवा के साथ शराब न लें क्योंकि इससे नींद और बढ़ सकती है। गाड़ी चलाने या मशीन चलाने से बचें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। 7 दिनों से अधिक इसका उपयोग न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 reskon dmr syrup Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves nasal congestion, sneezing, runny nose, and itching associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from nasal congestion and sneezing due to viral upper respiratory infections.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps reduce nasal congestion and pressure in sinusitis, though it does not treat the underlying infection.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Sometimes used to relieve nasal congestion that may contribute to middle ear fluid, but evidence is limited.","evidence":"Limited"}]

Off-label uses: [{"condition":"Motion sickness","description":"Chlorpheniramine's anticholinergic properties may help prevent motion sickness, but this is not a primary indication.","evidence":"Limited"},{"condition":"Insomnia","description":"Due to its sedative effects, it is sometimes used off-label as a sleep aid, but this is not recommended.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Sinusitis

📋 Drug Information

Generic Name(s)Phenylephrine (5mg/5ml) + Chlorpheniramine Maleate (2mg/5ml)
Brand Namereskon dmr syrup
ManufacturerParul Health Care Private Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) away from direct sunlight and moisture. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol and other CNS depressants while taking this medicine.
3
Do not drive or operate machinery until you know how this medicine affects you.
4
Do not use this medicine for more than 7 days without consulting a doctor.
5
Stay well hydrated to help thin nasal secretions.
6
If you have high blood pressure, monitor it regularly while on this medicine.
7
Consult your doctor before using this medicine if you are pregnant or breastfeeding.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
Sneezing
This medicine helps relieve sneezing due to allergies.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionPhenylephrine is absorbed from the gastrointestinal tract, but oral bioavailability is low due to extensive first-pass metabolism. Chlorpheniramine is well absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 2 to 6 hours.
DistributionPhenylephrine distribution is not well characterized. Chlorpheniramine is widely distributed throughout the body, including the central nervous system, and crosses the placenta and enters breast milk.
Protein BindingPhenylephrine protein binding is not well established. Chlorpheniramine is approximately 70% bound to plasma proteins.
MetabolismPhenylephrine undergoes extensive first-pass metabolism in the liver and gut wall, primarily by monoamine oxidase and sulfation. Chlorpheniramine is metabolized in the liver, primarily by CYP2D6 and CYP3A4.
Half-LifePhenylephrine elimination half-life is approximately 2 to 3 hours. Chlorpheniramine elimination half-life is approximately 12 to 43 hours, with an average of 20 hours.
ExcretionPhenylephrine is excreted in urine primarily as metabolites. Chlorpheniramine and its metabolites are excreted in urine.
BioavailabilityPhenylephrine oral bioavailability is approximately 38% due to first-pass metabolism. Chlorpheniramine oral bioavailability is approximately 25 to 50%.
Onset of ActionPhenylephrine onset of action is within 15 to 30 minutes. Chlorpheniramine onset of action is within 30 to 60 minutes.
Peak Plasma TimePhenylephrine peak plasma time is 1 to 2 hours. Chlorpheniramine peak plasma time is 2 to 6 hours.
Duration of ActionPhenylephrine duration of action is 4 to 6 hours. Chlorpheniramine duration of action is 4 to 6 hours, but sedative effects may last longer.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that causes vasoconstriction of blood vessels in the nasal mucosa, leading to reduced swelling and congestion. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, preventing histamine-mediated allergic responses such as sneezing, itching, and increased vascular permeability. Additionally, chlorpheniramine has anticholinergic properties that contribute to drying of secretions.

Mechanism Steps

1
Alpha-1 adrenergic receptor activation: Phenylephrine binds to alpha-1 receptors on vascular smooth muscle in the nasal mucosa, causing vasoconstriction and reduced blood flow, which decreases swelling and congestion.
2
Histamine H1 receptor blockade: Chlorpheniramine competitively blocks histamine at H1 receptors on endothelial cells and sensory nerve endings, preventing histamine-induced vasodilation, increased permeability, and itching.
3
Anticholinergic effects: Chlorpheniramine also blocks muscarinic acetylcholine receptors, reducing secretions and contributing to dry mouth and nose.

💡 How to Take reskon dmr syrup

Strength: Liquid: Phenylephrine 5mg/5ml + Chlorpheniramine Maleate 2mg/5ml

1Shake the bottle well before use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take orally, with or without food.
4Follow the dosage instructions provided by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 5-10 ml every 4-6 hours as needed, not to exceed 60 ml in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor for drowsiness, confusion, and urinary retention. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose adjustment may be necessary. Consult a doctor.
Maximum Daily DoseFor adults: 60 ml in 24 hours. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of reskon dmr syrup

✅ Common Side Effects

Drowsiness (Common (10-30%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (10-20%))
Sip water, chew sugarless gum, or use saliva substitutes.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid alcohol.
Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, tongue, or throat, difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you feel palpitations or irregular pulse.
Seizures (Very rare (<0.01%))
Seek emergency medical care if seizures occur.
Blood disorders (e.g., agranulocytosis, thrombocytopenia) (Very rare (<0.01%))
Report unusual bruising, bleeding, or signs of infection to your doctor.

⚠️ Rare Side Effects

Hallucinations
Discontinue and seek medical advice.
Confusion
Consult a doctor, especially in elderly patients.
Photosensitivity
Use sunscreen and protective clothing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
CNS depressants Moderate
Anticholinergics Moderate
CYP2D6 inhibitors Moderate
Antacids Minor
Digoxin Minor
Grapefruit juice Moderate
Alcohol Major

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergics (e.g., atropine, benztropine)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

🍷 Alcohol Interaction

Alcohol increases the sedative effects of chlorpheniramine and can lead to severe drowsiness, impaired coordination, and respiratory depression. Avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to phenylephrine, chlorpheniramine, or any component","Severe hypertension","Coronary artery disease","Use with MAOIs","Narrow-angle glaucoma","Urinary retention","Severe liver disease"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients due to increased risk of confusion and falls.","Do not use for more than 7 days without consulting a doctor.","Use with caution in patients with hypertension, diabetes, thyroid disease, or prostate enlargement.","May cause rebound congestion if used for more than 3 days."]

🤱 Lactation Safety

Chlorpheniramine passes into breast milk and may cause drowsiness in the infant. Phenylephrine may reduce milk supply. Consult a doctor before use.

💊 Overdose Management

Overdose may cause severe drowsiness, seizures, hypertension, and arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or difficulty urinating due to an enlarged prostate. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. If you are pregnant or breastfeeding, consult your doctor before use. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not use if the solution is discolored or contains particles.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. They may experience confusion, urinary retention, and falls. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination in pregnancy is not well established.

🏥 Post-Surgery Considerations

This medicine may interact with anesthetics and other medications used during surgery. Inform your surgeon and anesthesiologist that you are taking this medicine.

🦷 Dental Procedures

This medicine can cause dry mouth, which may increase the risk of dental caries. Inform your dentist if you are taking this medicine before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated to help thin nasal secretions.
🥗
Use a humidifier to keep indoor air moist.
😴
Avoid allergens such as dust, pollen, and pet dander.
💧
Get plenty of rest to support your immune system.
🧘
Wash your hands frequently to prevent infections.

🏋️ Exercise Considerations

This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Include vitamin C-rich foods like oranges and bell peppers.
Drink warm fluids like herbal tea to soothe your throat.
Avoid alcohol and caffeine, which can worsen dehydration.
Eat a balanced diet to support immune function.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. Avoid these activities until you know how the medicine affects you. Inform your employer if your job requires such activities.

🛑 When to Stop This Medicine

Stop taking this medicine if your symptoms persist beyond 7 days, if you experience severe side effects, or if your doctor advises discontinuation. Do not stop abruptly if you have been using it for a long time without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to the risk of rebound congestion, tolerance, and potential side effects such as drowsiness and anticholinergic effects. Use for more than 7 days should be under medical supervision. Regular monitoring of blood pressure and mental status is advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Helps clear nasal passages and reduce congestion without medication.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can prevent allergic rhinitis symptoms.

Evidence: Well-established
Intranasal corticosteroids

Prescription nasal sprays that reduce inflammation in the nasal passages.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are ill with a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She started this medicine as prescribed for her allergic rhinitis. Within 30 minutes, her sneezing and runny nose significantly reduced. She experienced mild drowsiness, so she took it at bedtime. She was advised not to drive after taking it.
💡 Lesson: Taking this medicine at bedtime can help manage drowsiness while providing symptom relief.
👤 A 60-year-old man with hypertension and cold
He used this medicine for nasal congestion but experienced a rise in blood pressure. His doctor advised him to stop and switch to a different decongestant. He was monitored closely.
💡 Lesson: Patients with hypertension should use this medicine with caution and monitor blood pressure.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Phenylephrine starts working within 15-30 minutes, while chlorpheniramine takes 30-60 minutes. Peak effects occur within 1-2 hours.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: Is it safe for children?

A: Pediatric dosing is not established. Consult a pediatrician before giving this medicine to a child.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my blood pressure?
  • Can I drive after taking this medicine?
  • Does it interact with my other medicines?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for reskon dmr syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine for weeks.
    Fact: It should not be used for more than 7 days without medical advice due to risk of rebound congestion and other side effects.

🔄 Alternative Options

Generic Alternatives

  • Phenylephrine + Chlorpheniramine Maleate liquid

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Phenylephrine + Chlorpheniramine","route":"Oral","common_use":"Allergic rhinitis, common cold"},{"medicine":"Pseudoephedrine + Chlorpheniramine","active_ingredients":"Pseudoephedrine + Chlorpheniramine","route":"Oral","common_use":"Nasal congestion, allergies"}]

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