Mozax MPS 5mg/125mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or cramping
- Blood in vomit or stool
- Difficulty breathing or swelling of face, lips, or throat
- Palpitations or irregular heartbeat
- Yellowing of skin or eyes
- Severe diarrhea or dehydration
- Persistent vomiting
If experiencing severe symptoms, call emergency services immediately.
What is regmotil mps 5 mg/125 mg tablet used for?
This medicine is a combination of Mosapride and Simethicone used to treat functional dyspepsia, bloating, and gas. Mosapride improves gastrointestinal motility, while Simethicone reduces gas bubbles. It is taken orally before meals, usually two to three times daily, as prescribed by a doctor.
- Generic Name: Mosapride (5mg) + Simethicone (125mg)
- Manufacturer: Bsp Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 regmotil mps 5 mg/125 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मोसाप्राइड और सिमेथिकोन का संयोजन है, जिसका उपयोग अपच, पेट फूलना, गैस, और पेट की परेशानी में किया जाता है। मोसाप्राइड पेट और आंतों की गति को बढ़ाता है, जिससे भोजन जल्दी पचता है, और सिमेथिकोन पेट में बनी गैस के बुलबुले को तोड़कर बाहर निकालने में मदद करता है। यह दवा आमतौर पर खाने से 15-30 मिनट पहले ली जाती है। यह डॉक्टर के पर्चे पर ही मिलती है और डॉक्टर की सलाह के अनुसार ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट दर्द, दस्त, जी मिचलाना, सिरदर्द और मुँह सूखना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको त्वचा पर चकत्ते, खुजली, चेहरे या गले में सूजन, सांस लेने में कठिनाई, या दिल की धड़कन में गड़बड़ी महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। इसे पानी के साथ, खाने से 15-30 मिनट पहले लें। शराब का सेवन न करें, क्योंकि इससे पेट की समस्या बढ़ सकती है। अगर आपको दिल, लीवर या किडनी की कोई बीमारी है, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों को डॉक्टर की सलाह के बिना न दें। दवा को ठंडी और सूखी जगह पर रखें।
💊 regmotil mps 5 mg/125 mg tablet Uses & Benefits
[{"condition":"Functional dyspepsia","description":"Relieves postprandial fullness, early satiety, epigastric pain, and bloating by enhancing gastric emptying and reducing gas retention.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD) adjunct","description":"May be used as an add-on therapy to reduce bloating and improve gastric motility in patients with GERD.","evidence":"Moderate"},{"condition":"Diabetic gastroparesis","description":"Helps improve gastric emptying and reduce symptoms of nausea, vomiting, and bloating in diabetic patients with delayed gastric emptying.","evidence":"Moderate"},{"condition":"Post-operative ileus","description":"May be used to stimulate bowel motility after surgery, though evidence is limited.","evidence":"Limited"},{"condition":"Chronic gastritis","description":"Provides symptomatic relief from bloating and dyspeptic symptoms associated with chronic gastritis.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Irritable bowel syndrome (IBS)","description":"Sometimes prescribed off-label to relieve bloating and improve bowel motility in IBS patients.","evidence":"Limited"},{"condition":"Functional constipation","description":"May be used off-label to promote bowel movements in patients with functional constipation.","evidence":"Limited"}]
Primary treatment for: Functional dyspepsia
Also treats: Gastroesophageal reflux disease (GERD), Diabetic gastroparesis, Chronic gastritis, Irritable bowel syndrome (IBS)
📋 Drug Information
| Generic Name(s) | Mosapride (5mg) + Simethicone (125mg) |
| Brand Name | regmotil mps 5 mg/125 mg tablet |
| Manufacturer | Bsp Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Mosapride acts as a selective serotonin 5-HT4 receptor agonist, which stimulates the release of acetylcholine from enteric neurons, thereby enhancing gastrointestinal motility and accelerating gastric emptying. Simethicone is a non-absorbed antifoaming agent that reduces the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce into larger bubbles that are easier to expel. Together, they improve symptoms of bloating, fullness, and delayed gastric emptying.
Mechanism Steps
💡 How to Take regmotil mps 5 mg/125 mg tablet
Strength: Mosapride 5 mg + Simethicone 125 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally 15 to 30 minutes before meals, typically two to three times daily, or as directed by your doctor. The dose may vary depending on the indication, severity of symptoms, and individual patient factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use with caution and follow the dose prescribed by your doctor. Regular monitoring of liver and kidney function is advised. |
| Renal Impairment | In patients with severe renal impairment, this medicine should be used with caution. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with severe hepatic impairment, this medicine should be used with caution. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 15 mg of Mosapride and 375 mg of Simethicone (three tablets per day), unless otherwise prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of regmotil mps 5 mg/125 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Atropine | Moderate | |
| Propranolol | Moderate | |
| Morphine | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor | |
| Clarithromycin | Major | |
| Phenytoin | Major |
🚨 Major Interactions
- QT-prolonging drugs (e.g., amiodarone, sotalol, quinidine)
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, hyoscyamine)
- Beta-blockers (e.g., propranolol, metoprolol)
- Opioid analgesics
🍷 Alcohol Interaction
Alcohol may worsen gastrointestinal symptoms such as bloating and dyspepsia, and may increase the risk of side effects such as dizziness and drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Mosapride, Simethicone, or any component of the formulation","Gastrointestinal obstruction, perforation, or bleeding","Severe hepatic impairment","Severe renal impairment","Patients with a history of QT prolongation or ventricular arrhythmias","Concurrent use with QT-prolonging drugs"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiac disease or electrolyte imbalances.","Avoid concurrent use with QT-prolonging drugs.","Monitor liver and kidney function in patients with hepatic or renal impairment.","Do not exceed the recommended dose.","Avoid alcohol while taking this medicine.","Consult your doctor if symptoms persist or worsen.","Not recommended for children unless prescribed by a pediatrician.","Use with caution in elderly patients."]
🤱 Lactation Safety
It is not known whether Mosapride or Simethicone are excreted in human breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause severe gastrointestinal symptoms, dizziness, and cardiac arrhythmias. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Take the tablet with a glass of water, preferably 15 to 30 minutes before meals, unless your doctor advises otherwise. Do not crush, chew, or break the tablet unless instructed. Avoid alcohol while taking this medicine, as it may worsen gastrointestinal symptoms and increase the risk of side effects. Inform your doctor if you have a history of heart rhythm disorders, liver disease, kidney disease, or electrolyte imbalances. Do not use this medicine for longer than prescribed without medical supervision. Keep out of reach of children. Store at room temperature away from moisture and direct sunlight. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Use with caution and follow the dose prescribed by your doctor. Regular monitoring of liver and kidney function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy is not well established.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to improve gastrointestinal motility, but only under medical supervision. Inform your surgeon if you are taking this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It is generally safe, but your dentist may need to take precautions if you have other medical conditions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness or palpitations, avoid strenuous activities and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some individuals. If affected, avoid driving or operating heavy machinery until you know how it affects you. Otherwise, it generally does not interfere with daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will advise whether to stop or adjust the dose.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Regular monitoring of liver and kidney function may be advised. Prolonged use of Mosapride may rarely cause cardiac arrhythmias. Do not use for extended periods without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent meals and avoiding trigger foods can help manage dyspepsia.
Evidence: Well-establishedYoga, meditation, and relaxation techniques can reduce stress-related gastrointestinal symptoms.
Evidence: ModerateMay help improve gut health and reduce bloating, though evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before any vaccination if you are unwell.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust your dosing schedule gradually to match local meal times. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts working within 30 to 60 minutes after oral administration. You may notice improvement in bloating and fullness within a few hours.
A: It is best taken 15 to 30 minutes before meals, unless your doctor advises otherwise.
A: It can be taken daily as prescribed, but long-term use should be monitored by your doctor.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for regmotil mps 5 mg/125 mg tablet
View AllAlternative brands with exact same active ingredient:
-
mozax mps 5mg/125mg tabletSun Pharmaceutical Industries Ltd ₹35.06 23.8% CHEAPER
-
mosid mps 5mg/125mg tabletTorrent Pharmaceuticals Ltd ₹36.05 21.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all stomach problems.
Fact: This medicine is specifically for functional dyspepsia and gas-related symptoms. It is not a cure for infections, ulcers, or other serious gastrointestinal conditions. - Myth: It is safe to take this medicine indefinitely without doctor supervision.
Fact: Long-term use should be monitored by a doctor. Regular check-ups may be needed to assess liver and kidney function. - Myth: You can take this medicine with alcohol without any issues.
Fact: Alcohol can worsen gastrointestinal symptoms and increase the risk of side effects. It is best to avoid alcohol while taking this medicine.
🔄 Alternative Options
Generic Alternatives
- Mosapride 5 mg + Simethicone 125 mg tablet (various manufacturers)
Brand Alternatives
- Mozax MPS 5mg/125mg tablet