Maxeron MPS 5 mg/125 mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Uncontrollable movements of the face, tongue, lips, or limbs.
- High fever with muscle rigidity and confusion.
- Swelling of the face, lips, throat, or difficulty breathing.
- Severe headache with blurred vision or chest pain.
- Signs of depression or thoughts of self-harm.
- Unusual bruising or bleeding.
- Severe abdominal pain or blood in vomit or stool.
If experiencing severe symptoms, call emergency services immediately.
What is reg mps tablet used for?
This medicine is a combination of metoclopramide and simethicone used to treat nausea, vomiting, bloating, and functional dyspepsia. It works by speeding up stomach emptying and reducing gas bubbles in the digestive tract.
- Generic Name: Metoclopramide (5mg) + Simethicone (125mg)
- Manufacturer: Cosme Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 reg mps tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेटोक्लोप्रामाइड और सिमेथिकोन का संयोजन है, जिसका उपयोग मतली, उल्टी, पेट में गैस, और अपच जैसी समस्याओं के इलाज के लिए किया जाता है। यह पेट को खाली करने की गति को बढ़ाती है और गैस के बुलबुले को कम करती है, जिससे पेट फूलना और बेचैनी कम होती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, बेचैनी, थकान, सिरदर्द, चक्कर आना और मुँह सूखना शामिल हैं। कभी-कभी मांसपेशियों में अकड़न, कंपन, या अनैच्छिक हरकतें हो सकती हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको चेहरे, जीभ या हाथ-पैरों में अनियंत्रित हरकतें दिखें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर खाने से पहले। इसका सेवन 12 हफ्तों से ज्यादा न करें। दवा लेने के बाद नींद या चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब न पिएं। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको किडनी या लीवर की समस्या है, तो डॉक्टर से सलाह लें।
💊 reg mps tablet Uses & Benefits
[{"condition":"Nausea and vomiting","description":"Helps relieve nausea and vomiting by speeding up stomach emptying and blocking vomiting signals in the brain.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Reduces symptoms such as bloating, early fullness, and upper abdominal discomfort by improving stomach motility and reducing gas.","evidence":"Moderate"},{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces heartburn and acid reflux by strengthening the lower esophageal sphincter and promoting stomach emptying.","evidence":"Moderate"},{"condition":"Diabetic gastroparesis","description":"Helps improve stomach emptying in people with diabetes who have delayed gastric emptying.","evidence":"Moderate"},{"condition":"Postoperative nausea and vomiting","description":"Used to prevent and treat nausea and vomiting after surgery.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine-associated nausea","description":"Sometimes used to relieve nausea that occurs with migraines, though not a primary migraine treatment.","evidence":"Limited"},{"condition":"Lactation stimulation","description":"Metoclopramide has been used off-label to increase breast milk production, but this is not recommended due to safety concerns.","evidence":"Limited"}]
Primary treatment for: Nausea and vomiting
Also treats: Functional dyspepsia, Gastroesophageal reflux disease, Diabetic gastroparesis
📋 Drug Information
| Generic Name(s) | Metoclopramide (5mg) + Simethicone (125mg) |
| Brand Name | reg mps tablet |
| Manufacturer | Cosme Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Metoclopramide blocks dopamine D2 receptors in the chemoreceptor trigger zone of the brain and in the gastrointestinal tract, which reduces nausea and vomiting and accelerates gastric emptying. It also antagonizes serotonin 5-HT3 receptors and sensitizes muscarinic receptors, contributing to its prokinetic effects. Simethicone is a surface-acting agent that reduces the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce and be expelled more easily, which relieves bloating and gas-related discomfort.
Mechanism Steps
💡 How to Take reg mps tablet
Strength: Each tablet contains metoclopramide 5 mg and simethicone 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken up to three times daily before meals, depending on the condition being treated. For nausea and vomiting, it may be taken as needed. For functional dyspepsia or reflux, it is often taken before meals. The maximum recommended dose is 30 mg of metoclopramide per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the side effects of metoclopramide, especially movement disorders. The dose should be started at the lower end of the range and adjusted carefully by a clinician. |
| Renal Impairment | In patients with severe kidney impairment (creatinine clearance less than 30 mL/min), the dose of metoclopramide should be reduced by 50% or the dosing interval extended. Consult a clinician for individualized dosing. |
| Hepatic Impairment | In patients with severe liver impairment, the dose of metoclopramide may need to be reduced. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 30 mg of metoclopramide (equivalent to 6 tablets of this 5 mg/125 mg strength) in divided doses. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of reg mps tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Haloperidol | Major | |
| MAOIs | Major | |
| Levodopa | Major | |
| Alcohol | Major | |
| Atropine | Moderate | |
| Opioids | Moderate | |
| Digoxin | Moderate | |
| Cyclosporine | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Antipsychotics (e.g., haloperidol, risperidone)
- Monoamine oxidase inhibitors (MAOIs)
- Levodopa
- Alcohol
⚡ Moderate Interactions
- Anticholinergics (e.g., atropine, benztropine)
- Opioid analgesics
- Digoxin
- Cyclosporine
- Serotonergic drugs (e.g., SSRIs, triptans)
🍷 Alcohol Interaction
Avoid drinking alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and the risk of movement-related side effects caused by metoclopramide.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to metoclopramide or simethicone.","Gastrointestinal obstruction, perforation, or bleeding.","Pheochromocytoma.","Seizure disorders.","History of tardive dyskinesia.","Parkinson's disease.","Concurrent use with levodopa or dopamine agonists."]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Do not use for more than 12 weeks without medical review due to risk of tardive dyskinesia.","Use with caution in patients with kidney or liver impairment.","May worsen symptoms of Parkinson's disease.","Can cause depression or suicidal thoughts; report mood changes to your doctor.","Use with caution in patients with heart failure, hypertension, or arrhythmias.","May increase prolactin levels and cause breast enlargement or milk production."]
🤱 Lactation Safety
Metoclopramide passes into breast milk and may cause side effects in the baby. It is not recommended during breastfeeding unless advised by a doctor. Simethicone is not absorbed and is unlikely to affect the breastfed infant.
💊 Overdose Management
Overdose of this medicine may cause drowsiness, confusion, extrapyramidal symptoms, and low blood pressure. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal if taken recently, and medications to control movement symptoms.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually before meals for best effect. Do not exceed the recommended dose or duration of treatment. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Do not drink alcohol while taking this medicine because it can worsen drowsiness and increase the risk of movement side effects. Inform your doctor if you have kidney or liver problems, heart failure, high blood pressure, diabetes, or a history of depression. Tell your doctor about all other medicines you are taking, especially antipsychotics, antidepressants, pain relievers, and heart medicines. Do not use this medicine for more than 12 weeks unless specifically advised by your doctor. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children and store it in its original packaging.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the side effects of metoclopramide, especially movement disorders such as tardive dyskinesia. The dose should be started at the lower end and adjusted carefully. Regular monitoring for movement symptoms is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Metoclopramide may be used in pregnancy if clearly needed, but the risks and benefits should be discussed with your doctor.
🏥 Post-Surgery Considerations
This medicine may be used to treat postoperative nausea and vomiting. Inform your surgeon and anesthesiologist if you are taking this medicine before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may interact with certain medicines used during dental procedures, and it can cause dry mouth, which may affect dental health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring balance until you know how it affects you. Light walking after meals can aid digestion.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause restlessness, which can impact concentration. Discuss with your doctor if your work requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience any unusual movements, severe side effects, or if your symptoms do not improve within a few days. Do not stop suddenly if you have been taking it for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine, especially beyond 12 weeks, increases the risk of tardive dyskinesia, a potentially irreversible movement disorder. Regular monitoring for movement symptoms is advised. It may also cause elevated prolactin levels, leading to breast enlargement or milk production. Periodic review with your doctor is necessary to assess the need for continued treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating small, frequent meals and avoiding trigger foods can help manage nausea and bloating.
Evidence: Well-establishedGinger may help reduce nausea, but evidence is limited.
Evidence: LimitedMay help with nausea and vomiting in some people.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. This medicine is not known to interact with vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If you are traveling across time zones, adjust your dosing schedule gradually and consult your doctor if unsure. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking it.
A: Some medicines can interact with this product. Always inform your doctor about all medicines you are taking.
A: It should not be used for more than 12 weeks without a doctor's review due to the risk of movement disorders.
A: Consult your doctor before taking this medicine during pregnancy. It may be used if clearly needed.
🤔 Common Patient Concerns
🔄 Substitutes for reg mps tablet
View AllAlternative brands with exact same active ingredient:
-
maxeron mps 5 mg/125 mg tabletWallace Pharmaceuticals Pvt Ltd ₹10.39 15.2% CHEAPER
-
perinorm mps 5 mg/125 mg tabletIpca Laboratories Ltd ₹12.50 2% COSTLIER
-
nausifar mps tabletInfar India Ltd ₹15.00 22.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for stomach problems.
Fact: This medicine should not be used for more than 12 weeks due to the risk of tardive dyskinesia. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol increases drowsiness and the risk of movement side effects. - Myth: This medicine is a painkiller.
Fact: This medicine is not a painkiller; it is used for nausea, vomiting, and bloating.
🔄 Alternative Options
Generic Alternatives
- Metoclopramide + Simethicone
Brand Alternatives
- Maxeron MPS