Recipro TS Tablet - Ciprofloxacin (500mg) + Tinidazole (NA) medicine

Recipro TS Tablet: Complete Medicine Guide

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🏭 Veritaz Healthcare Ltd 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Ciprofloxacin is generally avoided in pregnancy unless the benefit clearly outweighs the risk. Tinidazole is also used in pregnancy only when clearly indicated. This medicine should be used during pregnancy only if prescribed by a doctor after assessing the risk-benefit ratio. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for specific indications.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Tendon pain or swelling
  • Seizures or confusion

If experiencing severe symptoms, call emergency services immediately.

What is Recipro TS Tablet used for?

This medicine is a prescription antibiotic combination of ciprofloxacin and tinidazole used to treat mixed bacterial and protozoal infections, especially diarrheal illnesses. It is taken orally with food, and alcohol must be avoided during and for 72 hours after treatment.

  • Generic Name: Ciprofloxacin (500mg) + Tinidazole (NA)
  • Manufacturer: Veritaz Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Recipro TS Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सिप्रोफ्लोक्सासिन और टिनिडाजोल का संयोजन है, जिसका उपयोग बैक्टीरिया और प्रोटोजोआ से होने वाले मिश्रित संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से दस्त, पेचिश, अमीबiasis, जियार्डिया, पेट के अंदर के संक्रमण, और दांतों के संक्रमण में दी जाती है। यह दवा डॉक्टर के पर्चे के बिना नहीं लेनी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, मुँह में धातु जैसा स्वाद, सिरदर्द, चक्कर आना और भूख न लगना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन टेंडन टूटना, गंभीर एलर्जी, दौरे, और लीवर की समस्या हो सकती है। शराब का सेवन बिल्कुल न करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार पूरा कोर्स करें। इसे भोजन के साथ लें और पर्याप्त पानी पिएँ। एंटासिड, कैल्शियम, आयरन या जिंक के साथ 2 घंटे पहले या 6 घंटे बाद ही लें। शराब का सेवन पूरी तरह बंद करें। धूप से बचें और सनस्क्रीन लगाएँ। चक्कर आने पर वाहन न चलाएँ।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 Recipro TS Tablet Uses & Benefits

[{"condition":"Mixed bacterial and protozoal diarrhea","description":"Used to treat infectious diarrhea when both invasive bacteria and protozoa such as Giardia or Entamoeba are suspected or confirmed.","evidence":"Well-established"},{"condition":"Giardiasis","description":"Tinidazole component is effective against Giardia lamblia, and ciprofloxacin covers concurrent bacterial pathogens.","evidence":"Well-established"},{"condition":"Amoebic dysentery","description":"Tinidazole treats Entamoeba histolytica, while ciprofloxacin addresses secondary bacterial infection.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Covers aerobic gram-negative bacteria and anaerobic organisms commonly involved in intra-abdominal sepsis.","evidence":"Moderate"},{"condition":"Pelvic inflammatory disease","description":"Used in combination regimens for polymicrobial pelvic infections when appropriate.","evidence":"Moderate"},{"condition":"Dental and periodontal infections","description":"Covers oral anaerobes and facultative bacteria in severe dental abscesses when prescribed.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Traveler's diarrhea prophylaxis","description":"Sometimes considered for short-term prevention in high-risk travelers, but not routinely recommended due to resistance and side effects.","evidence":"Limited"},{"condition":"Refractory bacterial vaginosis","description":"Tinidazole component may be used in selected cases, but combination with ciprofloxacin is not standard.","evidence":"Limited"}]

Primary treatment for: Mixed bacterial and protozoal gastrointestinal infections

Also treats: Giardiasis, Amoebic dysentery, Intra-abdominal infections, Pelvic inflammatory disease, Dental infections

📋 Drug Information

Generic Name(s)Ciprofloxacin (500mg) + Tinidazole (NA)
Brand NameRecipro TS Tablet
ManufacturerVeritaz Healthcare Ltd
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture unless otherwise stated on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if you feel better.
3
Avoid alcohol completely during and for 72 hours after treatment.
4
Do not take antacids, calcium, iron, or zinc within 2 hours before or 6 hours after this medicine.
5
Use sunscreen and protective clothing because this medicine can increase sun sensitivity.
6
Report tendon pain, numbness, or severe diarrhea immediately.
7
Stay well hydrated throughout the day.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Diarrhea with fever
This medicine is commonly prescribed for mixed infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary
✅
Dental abscess
May be prescribed for dental infections.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCiprofloxacin is absorbed from the gastrointestinal tract after oral administration, with bioavailability of approximately 70 to 80 percent. Tinidazole is also well absorbed orally. Food may slightly delay absorption but does not significantly reduce the extent of absorption.
DistributionCiprofloxacin distributes widely into body tissues and fluids, including urine, bile, lung, prostate, and bone. Tinidazole distributes into tissues and crosses the blood-brain barrier to some extent. Both agents reach therapeutic concentrations in many infected sites.
Protein BindingCiprofloxacin is approximately 20 to 40 percent protein bound. Tinidazole is approximately 12 percent protein bound.
MetabolismCiprofloxacin undergoes partial hepatic metabolism, with several active and inactive metabolites. Tinidazole is metabolized in the liver, primarily by oxidation and conjugation.
Half-LifeThe elimination half-life of ciprofloxacin is approximately 3 to 5 hours in patients with normal renal function. The elimination half-life of tinidazole is approximately 12 to 14 hours.
ExcretionCiprofloxacin is excreted primarily unchanged in urine, with a smaller fraction in feces. Tinidazole is excreted mainly in urine and to a lesser extent in feces, partly as metabolites.
BioavailabilityCiprofloxacin oral bioavailability is approximately 70 to 80 percent. Tinidazole oral bioavailability is high, generally exceeding 90 percent.
Onset of ActionAntibacterial and antiprotozoal effects begin within a few hours after the first dose, but clinical improvement in symptoms may take 24 to 72 hours.
Peak Plasma TimeCiprofloxacin reaches peak plasma concentration approximately 1 to 2 hours after oral administration. Tinidazole reaches peak plasma concentration approximately 2 hours after oral administration.
Duration of ActionCiprofloxacin maintains antibacterial activity for approximately 12 hours after a standard dose. Tinidazole maintains antiprotozoal activity for approximately 24 hours or longer due to its longer half-life.

How It Works

Ciprofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication, repair, and supercoiling, leading to bacterial cell death. Tinidazole enters susceptible anaerobic bacteria and protozoa, where its nitro group is reduced to reactive intermediates that damage DNA and inhibit nucleic acid synthesis. The combination provides broad coverage against aerobic gram-negative bacteria and anaerobic bacteria or protozoa.

Mechanism Steps

1
Ciprofloxacin enters bacterial cell: Ciprofloxacin crosses the bacterial cell wall and cytoplasmic membrane.
2
Inhibition of DNA gyrase: Ciprofloxacin binds DNA gyrase and topoisomerase IV, blocking DNA replication and repair.
3
Bacterial DNA fragmentation: Failure of DNA supercoiling leads to double-strand breaks and bacterial death.
4
Tinidazole uptake by anaerobes: Tinidazole diffuses into anaerobic bacteria and protozoa, where low oxygen conditions favor nitro reduction.
5
Reactive intermediate formation: Reduced tinidazole metabolites bind DNA and cause strand breakage.
6
Microbial death: Combined DNA damage results in rapid killing of susceptible organisms.

💡 How to Take Recipro TS Tablet

Strength: Ciprofloxacin 500 mg and tinidazole as per formulation in an immediate-release oral tablet.

1Take the tablet with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow whole; do not crush or chew.
4Avoid antacids, calcium, iron, or zinc within 2 hours before or 6 hours after.
5Avoid alcohol completely during and for 72 hours after treatment.
6Complete the full prescribed course.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily, depending on the infection being treated, its severity, and the prescribing clinician's judgment. The exact dose and duration must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and local resistance patterns. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. They are at higher risk of tendon rupture, confusion, and cardiac arrhythmias. Close monitoring is advised.
Renal ImpairmentDose adjustment is required in patients with renal impairment. Ciprofloxacin dose should be reduced based on creatinine clearance. Tinidazole may also require adjustment in severe renal impairment. Consult a clinician for individualized dosing.
Hepatic ImpairmentCaution is advised in patients with hepatic impairment. Tinidazole is metabolized in the liver, and dose reduction may be needed in severe liver disease. Monitor liver function.
Maximum Daily DoseThe maximum daily dose must be determined by a qualified clinician based on the specific indication and patient factors. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Dairy products
Separate by at least 2 hours
Calcium reduces absorption.
Alcohol
Avoid completely
Risk of disulfiram-like reaction.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Recipro TS Tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food and stay hydrated. Consult doctor if persistent.
Diarrhea (Common (5-10%))
Drink fluids and avoid fatty foods. Seek care if bloody or severe.
Metallic taste (Common (5-10%))
Usually temporary. Chewing sugar-free gum may help.
Headache (Common (5-10%))
Rest and hydrate. Consult doctor if severe or persistent.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until it resolves.
Abdominal pain (Common (5-10%))
Take with meals. Report severe or worsening pain.

🚨 Serious Side Effects

Tendon rupture (Rare (<0.1%))
Stop the medicine and seek immediate medical attention if you develop tendon pain, swelling, or inability to move the affected limb.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you develop facial swelling, difficulty breathing, or widespread rash.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek medical care if you develop severe, persistent, or bloody diarrhea.
Seizures (Rare (<0.1%))
Stop the medicine and seek emergency care if you have a seizure.
Liver injury (Rare (<0.1%))
Report yellowing of eyes or skin, dark urine, or severe fatigue immediately.
Blood dyscrasias (Rare (<0.1%))
Seek medical attention for unusual bruising, bleeding, or persistent fever.

⚠️ Rare Side Effects

Peripheral neuropathy
Report numbness, tingling, or burning in hands or feet to your doctor.
QT prolongation
Seek medical advice if you experience palpitations or fainting.
Photosensitivity
Use sunscreen and avoid prolonged sun exposure.
Crystalluria
Drink plenty of water and report painful urination or blood in urine.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tizanidine Major
Theophylline Major
Warfarin Major
Antacids Major
Alcohol Major
Caffeine Moderate
Cyclosporine Moderate
Phenytoin Moderate
Methotrexate Moderate
Corticosteroids Moderate

🚨 Major Interactions

  • Tizanidine
  • Theophylline
  • Warfarin
  • Antacids, calcium, iron, zinc
  • Alcohol

⚡ Moderate Interactions

  • Caffeine
  • Cyclosporine
  • Phenytoin
  • Methotrexate
  • Oral hypoglycemics

🍷 Alcohol Interaction

Alcohol must be strictly avoided during treatment with this medicine and for at least 72 hours after the last dose. Tinidazole can cause a disulfiram-like reaction characterized by flushing, severe nausea, vomiting, palpitations, and low blood pressure. Alcohol may also worsen dizziness and liver-related side effects.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to ciprofloxacin, other quinolones, tinidazole, or nitroimidazoles","Myasthenia gravis","History of tendon disorders with fluoroquinolones","Severe renal impairment without dose adjustment","Severe hepatic impairment","Pregnancy unless clearly needed","Breastfeeding without medical advice","Children unless specifically prescribed","Alcohol use during treatment"]

⚠️ Warnings & Precautions

["Avoid alcohol during and for 72 hours after treatment.","Do not take with antacids, calcium, iron, or zinc within 2 hours before or 6 hours after.","May cause dizziness; avoid driving until you know how it affects you.","May cause photosensitivity; use sunscreen.","Risk of tendon rupture, especially in elderly and corticosteroid users.","May worsen myasthenia gravis.","May cause peripheral neuropathy.","May cause severe diarrhea; report bloody or persistent diarrhea.","May cause seizures; caution in epilepsy.","May cause dysglycemia in diabetic patients."]

🤱 Lactation Safety

Ciprofloxacin and tinidazole are excreted in breast milk. Breastfeeding is generally not recommended during treatment and for at least 72 hours after the last dose unless advised otherwise by a doctor.

💊 Overdose Management

Overdose may cause nausea, vomiting, dizziness, and seizures. There is no specific antidote. Treatment is supportive with hydration, monitoring of vital signs, and management of symptoms. Seek immediate medical attention if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember if less than half the dosing interval has passed. If more than half the interval has passed, skip the missed dose and continue with the regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor and complete the full course even if you feel better after a few days. Swallow the tablet whole with a full glass of water and take it with food to reduce stomach upset. Avoid alcohol completely during treatment and for at least three days after the last dose. Do not take antacids, calcium, iron, zinc, or multivitamins within two hours before or six hours after this medicine because they reduce ciprofloxacin absorption. Use sunscreen and protective clothing because this medicine can make your skin more sensitive to sunlight. Drink plenty of fluids to keep your urine dilute and reduce the risk of crystal formation. Do not drive or operate heavy machinery if you feel dizzy or confused. Tell your doctor if you have kidney disease, liver disease, epilepsy, myasthenia gravis, tendon problems, or heart rhythm problems before starting this medicine. Stop the medicine and seek immediate medical help if you develop tendon pain, swelling, numbness, severe diarrhea, yellowing of the eyes, or an allergic reaction.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, confusion, and cardiac arrhythmias. Dose adjustment may be needed based on renal function.

🤰 Pregnancy Planning (TTC)

This medicine is generally avoided in pregnancy unless clearly needed. Discuss with your doctor if you are planning pregnancy or are pregnant.

🏥 Post-Surgery Considerations

This medicine may be prescribed after surgery for intra-abdominal infections. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

This medicine may be prescribed for dental infections. Inform your dentist about all medicines you are taking.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water to stay hydrated.
🥗
Avoid alcohol completely during treatment.
😴
Eat a balanced diet to support recovery.
💧
Get adequate rest.
🧘
Use sunscreen when outdoors.
🌞
Wash hands frequently to prevent reinfection.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting if you experience tendon pain, dizziness, or fatigue. Consult your doctor before resuming intense activity.

🥗 Diet Recommendations

Stay well hydrated
Include probiotics like yogurt if advised
Avoid fatty and spicy foods
Eat small frequent meals

💼 Impact on Daily Work & Life

This medicine may cause dizziness or confusion. Avoid driving or operating heavy machinery until you know how it affects you. Take sick leave if symptoms are severe.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as tendon pain, severe diarrhea, allergic reaction, or seizures, stop immediately and seek medical help.

📅 Long-Term Use Effects

Long-term use can lead to antibiotic resistance, gut flora imbalance, and rare but serious effects such as peripheral neuropathy, tendon damage, and liver or kidney issues. Regular monitoring may be needed if prolonged therapy is required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral rehydration therapy

Essential for managing dehydration in diarrheal illness.

Evidence: Well-established
Probiotics

May help restore gut flora during and after antibiotic therapy.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics may reduce the effectiveness of live bacterial vaccines such as typhoid vaccine. Consult your doctor about timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If traveling across time zones, continue your dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute diarrheal illness
He was prescribed this medicine for suspected mixed bacterial and protozoal diarrhea. He took it with food and completed the course. His symptoms improved within three days, and he avoided alcohol as advised.
💡 Lesson: Taking the medicine with food and completing the course leads to better outcomes.
👤 A 50-year-old woman with dental abscess
She received this medicine after a dental procedure. She experienced mild nausea but no serious side effects. She was advised to avoid antacids and alcohol, and her infection resolved.
💡 Lesson: Following dietary and medication precautions prevents complications.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 72 hours, but you must complete the full course.

Q: Can I take it with food?

A: Yes, take it with food to reduce stomach upset.

Q: What if I miss a dose?

A: Take it as soon as you remember if less than half the interval has passed; otherwise skip and continue.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure any diarrhea.
    Fact: It only works for specific bacterial and protozoal infections. Viral diarrhea does not respond.
  • Myth: You can stop when you feel better.
    Fact: You must complete the full course to prevent resistance and relapse.
  • Myth: Alcohol is fine in small amounts.
    Fact: Even small amounts can cause a severe disulfiram-like reaction.
  • Myth: It is safe to take with antacids.
    Fact: Antacids reduce absorption. Separate doses by at least 2 hours.

🔄 Alternative Options

Generic Alternatives

  • Ciprofloxacin and tinidazole combination generics

Brand Alternatives

  • Ciplox TZ
  • Cifran CT
  • Cipro TZ
  • Zoxan TZ

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ciprofloxacin + Tinidazole","class":"Fluoroquinolone + Nitroimidazole","primary_use":"Mixed bacterial and protozoal infections"},{"medicine":"Ofloxacin and tinidazole","composition":"Ofloxacin + Tinidazole","class":"Fluoroquinolone + Nitroimidazole","primary_use":"Similar infections"},{"medicine":"Metronidazole and ciprofloxacin","composition":"Metronidazole + Ciprofloxacin","class":"Nitroimidazole + Fluoroquinolone","primary_use":"Anaerobic and aerobic infections"}]

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