Acidom 10 mg/150 mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or persistent vomiting
- Irregular heartbeat, palpitations, or fainting
- Muscle stiffness, tremors, or difficulty speaking
- Swelling of face, lips, or throat, or difficulty breathing
- Yellowing of skin or eyes, or dark urine
- Unusual fatigue, fever, or sore throat
If experiencing severe symptoms, call emergency services immediately.
What is ranidone 10mg/150mg tablet used for?
This medicine is a combination of Domperidone and Ranitidine used to treat acid reflux, heartburn, and nausea. It works by reducing stomach acid and improving gastric emptying. It is available by prescription only.
- Generic Name: Domperidone (10mg) + Ranitidine (150mg)
- Manufacturer: The Pharmed Research Lab Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ranidone 10mg/150mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और रैनिटिडीन का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, सीने में जलन, अपच और मतली के इलाज के लिए किया जाता है। यह पेट में एसिड को कम करती है और पेट खाली होने की गति को बढ़ाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुँह सूखना, सिरदर्द, दस्त और पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन दिल की धड़कन अनियमित हो सकती है। कोई भी असामान्य लक्षण होने पर डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। गाड़ी चलाने या मशीनरी चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब का सेवन न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 ranidone 10mg/150mg tablet Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine helps reduce acid reflux and heartburn by decreasing stomach acid production and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It relieves symptoms like bloating, early satiety, and upper abdominal discomfort by enhancing gastric motility and reducing acid.","evidence":"Moderate"},{"condition":"Nausea and vomiting associated with delayed gastric emptying","description":"Domperidone component helps reduce nausea and vomiting by blocking dopamine receptors in the chemoreceptor trigger zone.","evidence":"Well-established"},{"condition":"Gastritis","description":"Ranitidine reduces acid secretion, providing relief from gastritis symptoms.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed off-label to improve gastric emptying in diabetic patients with gastroparesis.","evidence":"Limited"},{"condition":"Prevention of aspiration during anesthesia","description":"Rarely used off-label to reduce gastric volume and acidity before surgery.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Gastritis, Nausea and vomiting
📋 Drug Information
| Generic Name(s) | Domperidone (10mg) + Ranitidine (150mg) |
| Brand Name | ranidone 10mg/150mg tablet |
| Manufacturer | The Pharmed Research Lab Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Domperidone is a peripheral dopamine D2 receptor antagonist that blocks dopamine receptors in the gastrointestinal tract, particularly in the stomach and duodenum. This action enhances gastric motility and accelerates gastric emptying without affecting the central nervous system significantly. Ranitidine is a competitive histamine H2-receptor antagonist that reduces gastric acid secretion by blocking histamine's action on parietal cells. Together, they provide symptomatic relief from acid reflux and dyspepsia by both reducing acid and improving gut movement.
Mechanism Steps
💡 How to Take ranidone 10mg/150mg tablet
Strength: Each tablet contains Domperidone 10 mg and Ranitidine 150 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally 15-30 minutes before meals, typically twice daily or as directed by your doctor. The dose may be adjusted based on your condition and response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment due to reduced renal function. Use with caution and monitor for side effects such as confusion or cardiac arrhythmias. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Ranitidine dose should be reduced in patients with renal impairment (creatinine clearance <50 mL/min). Domperidone should be used with caution. Consult your doctor for appropriate dose adjustment. |
| Hepatic Impairment | Domperidone is contraindicated in moderate to severe hepatic impairment. In mild impairment, use with caution. Ranitidine dose may need adjustment. Consult your doctor. |
| Maximum Daily Dose | Domperidone: 30 mg per day (in divided doses) for short-term use. Ranitidine: 300 mg per day. Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ranidone 10mg/150mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Amiodarone | Major | |
| Warfarin | Moderate | |
| Antacids | Moderate | |
| Metoclopramide | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin, ritonavir
- QT-prolonging drugs (e.g., amiodarone, sotalol, quinidine)
⚡ Moderate Interactions
- Antacids
- Warfarin
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach bleeding and worsen side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to domperidone or ranitidine","Prolactin-releasing pituitary tumor (prolactinoma)","Moderate to severe hepatic impairment","Known QT prolongation or family history of long QT syndrome","Concomitant use with potent CYP3A4 inhibitors that prolong QT","Gastrointestinal hemorrhage, mechanical obstruction, or perforation"]
⚠️ Warnings & Precautions
["Use with caution in patients with kidney disease; dose adjustment may be needed.","Avoid in patients with pre-existing cardiac disease or electrolyte abnormalities.","May cause drowsiness; avoid driving or operating machinery until effects are known.","Do not use for prolonged periods without medical supervision.","Elderly patients may be more sensitive to side effects, especially confusion with ranitidine.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Domperidone is excreted in breast milk and may cause side effects in the infant. Ranitidine also passes into breast milk. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose may cause drowsiness, extrapyramidal symptoms, and cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be considered if within 1 hour of ingestion. Monitor ECG and vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness or dizziness. Do not consume alcohol while taking this medicine, as it can increase the risk of stomach bleeding and worsen side effects. Inform your doctor if you have kidney or liver disease, as dose adjustments may be needed. If you are pregnant or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for longer than 12 weeks without medical advice. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more prone to side effects such as confusion, drowsiness, and cardiac arrhythmias. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. It is not recommended unless clearly needed. Alternative treatments may be considered.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to prevent nausea and vomiting, but only under medical supervision. Inform your surgeon if you are taking this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with certain anesthetics or medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid vigorous exercise immediately after meals as it may worsen reflux. Light walking after meals can aid digestion. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause dry mouth, which can be managed by drinking water.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as irregular heartbeat, muscle stiffness, or allergic reactions. Do not stop abruptly without medical advice if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to increased prolactin levels, causing breast enlargement or discharge. It may also increase the risk of cardiac arrhythmias. Regular monitoring of kidney and liver function is advised. Do not use for more than 12 weeks without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and elevating the head of the bed can reduce reflux symptoms.
Evidence: Well-establishedMay be prescribed instead of H2 blockers for more potent acid suppression.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before any vaccination if you are on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually under medical guidance. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes for nausea and 1-3 hours for acid reduction. Full effects may take a few days.
A: Inform your doctor about all medicines you take, especially ketoconazole, clarithromycin, or warfarin, as interactions may occur.
A: Consult your doctor. It is not recommended unless clearly needed, as safety data are limited.
🤔 Common Patient Concerns
🔄 Substitutes for ranidone 10mg/150mg tablet
View AllAlternative brands with exact same active ingredient:
-
randex 10 mg/150 mg tabletZee Laboratories ₹1.98 71.8% CHEAPER
-
reloc dm 10 mg/150 mg tabletReddy Pharmaceuticals ₹4.45 36.7% CHEAPER
-
raninec dm 10mg/150mg tabletNectar Biopharma Pvt Limited ₹5.20 26% CHEAPER
-
ranloc dm tabletIntas Pharmaceuticals Ltd ₹5.26 25.2% CHEAPER
-
zynol dm 10 mg/150 mg tabletMicro Labs Ltd ₹5.26 25.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure acidity permanently.
Fact: It provides symptomatic relief but does not cure the underlying cause. Lifestyle changes are important. - Myth: It is safe to take indefinitely.
Fact: Long-term use should be avoided without medical supervision due to potential side effects.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Ranitidine generic tablets