Arorab IT 20mg/150mg Capsule SR: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or cramping
- Difficulty breathing or swelling of face, lips, or throat
- Chest pain or irregular heartbeat
- Severe headache with vision changes
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
- Persistent vomiting or inability to keep fluids down
If experiencing severe symptoms, call emergency services immediately.
What is rablik-isr 20mg/150mg capsule used for?
This medicine is a combination of Rabeprazole (20 mg) and Itopride (150 mg) used to treat acid reflux, heartburn, and functional dyspepsia. It works by reducing stomach acid and improving gastric motility. It is usually taken once daily before breakfast.
- Generic Name: Rabeprazole (20mg) + Itopride (150mg)
- Manufacturer: Blubell Pharma
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 rablik-isr 20mg/150mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा रैबेप्राजोल और आइटोप्राइड का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, हार्टबर्न, अपच और गैस्ट्रिक समस्याओं के इलाज के लिए किया जाता है। यह पेट में एसिड के उत्पादन को कम करती है और पेट की गति को बढ़ाती है, जिससे भोजन आसानी से पचता है। यह दवा आमतौर पर सुबह नाश्ते से पहले एक बार ली जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, मतली, दस्त, पेट दर्द और मुंह सूखना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, चक्कर आना, या दिल की धड़कन तेज होना हो सकता है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। कैप्सूल को चबाएं या तोड़ें नहीं, पूरा निगल लें। इसे सुबह खाली पेट लें। शराब का सेवन न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को बच्चों से दूर रखें।
💊 rablik-isr 20mg/150mg capsule Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by suppressing gastric acid secretion and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps relieve symptoms like bloating, early satiety, and upper abdominal discomfort by enhancing gastric motility and reducing acid.","evidence":"Moderate"},{"condition":"Non-ulcer dyspepsia","description":"Used to manage dyspeptic symptoms when no ulcer is present, combining acid suppression and prokinetic effects.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"May improve gastric emptying and reduce symptoms like nausea and vomiting in diabetic or idiopathic gastroparesis.","evidence":"Limited"},{"condition":"Chronic gastritis","description":"Provides symptomatic relief by reducing acid exposure and promoting gastric motility.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Refractory GERD","description":"Sometimes prescribed when standard proton pump inhibitor therapy alone is insufficient.","evidence":"Limited"},{"condition":"Prevention of NSAID-induced dyspepsia","description":"May be used to prevent stomach upset in patients on long-term NSAIDs, though not a standard indication.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Non-ulcer dyspepsia, Gastroparesis, Chronic gastritis
📋 Drug Information
| Generic Name(s) | Rabeprazole (20mg) + Itopride (150mg) |
| Brand Name | rablik-isr 20mg/150mg capsule |
| Manufacturer | Blubell Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Rabeprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in gastric parietal cells, thereby suppressing both basal and stimulated acid secretion. Itopride is a prokinetic agent that works by blocking dopamine D2 receptors and inhibiting acetylcholinesterase, which increases acetylcholine levels in the gastrointestinal tract. This dual action enhances gastric motility, accelerates gastric emptying, and improves coordination between the stomach and duodenum. Together, they reduce acid exposure and improve symptoms of dyspepsia and reflux.
Mechanism Steps
💡 How to Take rablik-isr 20mg/150mg capsule
Strength: Capsule containing Rabeprazole 20 mg and Itopride 150 mg in sustained-release form.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule taken orally once daily on an empty stomach, at least 30 minutes before breakfast. However, the dose and duration of treatment must be individualized by a qualified clinician based on the specific indication, severity of symptoms, age, weight, and renal and hepatic function. Do not self-adjust the dose. Follow your doctor's instructions exactly. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be necessary based on renal and hepatic function. Use with caution and monitor for side effects. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually needed. In severe renal impairment, dose reduction may be required. Consult your doctor for individualized dosing. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is usually needed. In severe hepatic impairment, dose reduction may be required. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule (Rabeprazole 20 mg + Itopride 150 mg) per day. Do not exceed this dose unless directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of rablik-isr 20mg/150mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Atazanavir | Major | |
| Ketoconazole | Major | |
| Methotrexate | Major | |
| Warfarin | Major | |
| Digoxin | Moderate | |
| Clopidogrel | Moderate | |
| Anticholinergics | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor | |
| Alcohol | Moderate |
🚨 Major Interactions
- Atazanavir
- Ketoconazole, Itraconazole
- Methotrexate
- Warfarin
⚡ Moderate Interactions
- Digoxin
- Clopidogrel
- Anticholinergic drugs
🍷 Alcohol Interaction
Alcohol may increase stomach acid production and irritate the stomach lining, reducing the effectiveness of this medicine and increasing the risk of gastrointestinal side effects. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Rabeprazole, Itopride, or any component of the formulation","Gastrointestinal bleeding or obstruction","Severe hepatic impairment","Severe renal impairment","Pregnancy (unless clearly needed)","Breastfeeding (unless clearly needed)"]
⚠️ Warnings & Precautions
["Do not use for immediate relief of acute heartburn.","May increase the risk of bone fractures with long-term use.","May cause low magnesium levels with prolonged use.","May increase the risk of Clostridium difficile-associated diarrhea.","Use with caution in patients with liver or kidney disease.","May cause drowsiness or dizziness; avoid driving or operating machinery until you know how it affects you.","Do not crush, chew, or break the capsule; swallow whole.","Inform your doctor if you have a history of QT prolongation or cardiac arrhythmias.","Avoid alcohol while taking this medicine.","Do not share this medicine with others."]
🤱 Lactation Safety
It is not known whether Rabeprazole and Itopride are excreted in human breast milk. Animal studies have shown excretion of Rabeprazole in milk. Because many drugs are excreted in human milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose of this medicine may cause symptoms such as severe drowsiness, confusion, nausea, vomiting, and rapid heartbeat. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the overdose is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole with a glass of water. It is best taken on an empty stomach, at least 30 minutes before breakfast, unless your doctor advises otherwise. Avoid alcohol while taking this medicine as it may worsen stomach irritation. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children. Store at room temperature away from moisture and direct sunlight. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and low magnesium levels. Dose adjustment may be needed based on renal and hepatic function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is classified as Pregnancy Category C, meaning risk cannot be ruled out. Your doctor may consider alternative treatments.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist about this medicine. It may need to be stopped temporarily before certain surgeries, especially those involving the gastrointestinal tract.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may affect bleeding risk or interact with medications used during dental procedures. No routine adjustment is usually needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, avoid vigorous exercise immediately after meals as it may worsen reflux. If you experience dizziness or fatigue, avoid strenuous activities until you know how the medicine affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue your daily activities, but take precautions if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Abrupt discontinuation may cause rebound acid hypersecretion.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to low magnesium levels, vitamin B12 deficiency, increased risk of bone fractures, and Clostridium difficile-associated diarrhea. Periodic monitoring of magnesium, vitamin B12, and bone density may be advised. It is important to review the need for continued therapy with your doctor regularly.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and avoiding trigger foods can complement medicine.
Evidence: Well-establishedSome herbs like ginger or licorice may help, but evidence is limited and they may interact with medicines.
Evidence: LimitedMay help reduce reflux symptoms in some patients, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for any vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking it at your usual morning time or adjust gradually as advised by your doctor. Keep it in your carry-on luggage to avoid loss. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Rabeprazole starts reducing acid within 1 hour, but noticeable symptom relief may take 1 to 2 days. Itopride's prokinetic effect begins within 30 to 60 minutes.
A: It is best taken on an empty stomach, at least 30 minutes before breakfast. Food may delay absorption.
A: Take it as soon as you remember. If it's almost time for the next dose, skip the missed dose. Do not double dose.
A: Long-term use may require monitoring of magnesium, vitamin B12, and bone health. Consult your doctor regularly.
A: Do not stop without consulting your doctor, as symptoms may rebound.
🤔 Common Patient Concerns
🔄 Substitutes for rablik-isr 20mg/150mg capsule
View AllAlternative brands with exact same active ingredient:
-
stayhappi rabeprazole+itopride 20mg/150mg capsuleSarvagunaushdhi Pvt Ltd ₹30.00 76.7% CHEAPER
-
rabepride 20mg/150mg tabletKinesis Pharmaceuticals Pvt Ltd ₹48.75 62.2% CHEAPER
-
razo ir 20mg/150mg tabletDr Reddy's Laboratories Ltd ₹70.31 45.5% CHEAPER
-
Rezole-IT 20mg/150mg CapsuleRitz Pharma ₹70.31 45.5% CHEAPER
-
koserab it 20mg/150mg capsule srKosmed Formulations ₹74.00 42.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for immediate relief of heartburn.
Fact: This medicine is not for immediate relief. It is a long-acting medication for chronic conditions and should be taken as prescribed. - Myth: It is safe to take this medicine indefinitely without monitoring.
Fact: Long-term use requires periodic monitoring of magnesium, vitamin B12, and bone health. Consult your doctor regularly. - Myth: This medicine can be taken with alcohol without any issues.
Fact: Alcohol can worsen stomach irritation and reduce the effectiveness of this medicine. It is best avoided.
🔄 Alternative Options
Generic Alternatives
- Rabeprazole + Itopride combination capsules available from various manufacturers.
Brand Alternatives
- Arorab IT 20mg/150mg capsule SR