qril tablet - Guaifenesin (100mg) + Bromhexine (8mg) medicine

Leekuf Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Egis Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in sputum or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Persistent fever

If experiencing severe symptoms, call emergency services immediately.

What is qril tablet used for?

This medicine is a combination of Guaifenesin and Bromhexine used to treat productive cough by thinning mucus and making it easier to cough out. It is taken orally with food, usually two to three times a day, and should not be used for more than 7 days without medical advice.

  • Generic Name: Guaifenesin (100mg) + Bromhexine (8mg)
  • Manufacturer: Egis Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 qril tablet के बारे में (Hindi Summary)

उपयोग: यह दवा गुआइफेनेसिन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी और छाती में जकड़न को कम करने के लिए किया जाता है। यह बलगम को पतला करके उसे बाहर निकालने में मदद करती है। यह आमतौर पर ब्रोंकाइटिस, सीओपीडी और श्वसन संक्रमण में उपयोग की जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, सिरदर्द और पेट की गड़बड़ी शामिल हैं। कभी-कभी एलर्जी, चक्कर आना और नींद आना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर गंभीर दाने हों तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। दवा लेते समय भरपूर पानी पिएं। यदि आपको चक्कर या नींद आती है तो वाहन चलाने या मशीन चलाने से बचें। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें। यदि खांसी ठीक न हो या बुखार, दाने या सांस लेने में कठिनाई हो तो डॉक्टर से संपर्क करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 qril tablet Uses & Benefits

[{"condition":"Productive cough associated with respiratory tract infections","description":"Helps loosen and thin mucus in the airways, making it easier to cough out.","evidence":"Well-established"},{"condition":"Bronchitis","description":"Used to relieve chest congestion and facilitate expectoration in acute and chronic bronchitis.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May help in clearing mucus from the airways in patients with COPD, but should be used under medical supervision.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to help thin mucus in sinus infections, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Productive cough

Also treats: Bronchitis, COPD, Respiratory tract infections

📋 Drug Information

Generic Name(s)Guaifenesin (100mg) + Bromhexine (8mg)
Brand Nameqril tablet
ManufacturerEgis Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Drink plenty of water throughout the day to help loosen mucus.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual bleeding or bruising immediately.
7
Do not use this medicine for dry cough; it is only for productive cough.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not for dry cough.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionGuaifenesin is rapidly absorbed from the gastrointestinal tract after oral administration. Bromhexine is also well absorbed orally. However, specific absorption data for this combination product are not established from the available information.
DistributionGuaifenesin and Bromhexine are distributed widely throughout the body, including the respiratory tract. Protein binding information is not established from the available information.
Protein BindingNot established from the available information.
MetabolismGuaifenesin is metabolized in the liver, primarily by oxidation. Bromhexine undergoes extensive first-pass metabolism in the liver, where it is converted to its active metabolite, ambroxol. Specific metabolic pathways for this combination are not established from the available information.
Half-LifeThe elimination half-life of Guaifenesin is approximately 1 hour. The elimination half-life of Bromhexine is not established from the available information.
ExcretionGuaifenesin and its metabolites are excreted primarily in the urine. Bromhexine and its metabolites are also excreted mainly in the urine. Specific excretion data for this combination are not established from the available information.
BioavailabilityThe oral bioavailability of Guaifenesin is approximately 60%. The bioavailability of Bromhexine is not established from the available information.
Onset of ActionThe onset of action for Guaifenesin is typically within 30 minutes to 1 hour after oral administration. The onset of action for Bromhexine is not established from the available information.
Peak Plasma TimePeak plasma concentrations of Guaifenesin are reached within 1 to 2 hours after oral administration. The peak plasma time for Bromhexine is not established from the available information.
Duration of ActionThe duration of action for Guaifenesin is approximately 4 to 6 hours. The duration of action for Bromhexine is not established from the available information.

How It Works

This medicine combines two active ingredients with complementary actions. Guaifenesin is an expectorant that works by increasing the volume and reducing the viscosity of mucus in the respiratory tract. It does this by drawing water into the mucus, making it thinner and easier to cough up. Bromhexine is a mucolytic that breaks down the chemical bonds in mucus, further reducing its thickness and stickiness. Together, they help clear the airways and make coughs more productive.

Mechanism Steps

1
Guaifenesin increases mucus hydration: Guaifenesin draws water into the mucus, making it less viscous and easier to expel.
2
Bromhexine breaks down mucus structure: Bromhexine disrupts the disulfide bonds in mucoproteins, further thinning the mucus.
3
Enhanced ciliary clearance: The thinned mucus is more easily moved by the cilia and coughed out.

💡 How to Take qril tablet

Strength: Tablet containing Guaifenesin 100 mg and Bromhexine 8 mg.

1Take this medicine orally with a glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take it at the same times each day to maintain consistent levels.
5Drink plenty of water throughout the day to help loosen mucus.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally two to three times a day, or as directed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Use with caution and consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be needed in patients with kidney disease. Consult your doctor.
Hepatic ImpairmentDose adjustment may be needed in patients with liver disease. Consult your doctor.
Maximum Daily DoseThe maximum daily dose of this medicine is not established from the available information. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Water
Drink plenty
Helps loosen mucus.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of qril tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated and avoid heavy meals. Consult your doctor if vomiting continues.
Diarrhea (Common (5-10%))
Drink plenty of fluids. If diarrhea is severe or persistent, seek medical advice.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if headache is severe or persistent.
Stomach upset (Common (5-10%))
Take with food or milk to minimize stomach upset.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Stop taking this medicine and seek immediate medical attention if you develop a painful rash, blistering, or peeling skin.

⚠️ Rare Side Effects

Dizziness
Avoid driving or operating machinery until you know how this medicine affects you.
Drowsiness
Avoid activities requiring alertness. Consult your doctor if drowsiness is bothersome.
Increased heart rate
Report to your doctor if you notice a persistent fast heartbeat.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Anticholinergics Moderate
Cough suppressants Moderate
Antibiotics Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine)
  • Cough suppressants (e.g., codeine)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and stomach upset. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to Guaifenesin or Bromhexine or any component of this medicine.","Severe liver disease.","Severe kidney disease.","Children under 12 years of age (unless prescribed by a doctor).","Persistent cough with excessive secretions."]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose.","Drink plenty of water while taking this medicine.","Avoid driving or operating machinery if you feel dizzy or drowsy.","Do not take this medicine for more than 7 days without consulting a doctor.","Consult your doctor if you have a history of liver or kidney disease.","Inform your doctor if you are pregnant or breastfeeding.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether Guaifenesin and Bromhexine pass into breast milk. Consult your doctor before taking this medicine while breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include severe nausea, vomiting, diarrhea, and abdominal pain. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose. Drink plenty of water while taking this medicine to help loosen mucus. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not take this medicine for more than 7 days without consulting your doctor. If your cough persists or worsens, or if you develop a fever, rash, or difficulty breathing, seek medical attention. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Use with caution and consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning to become pregnant. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may affect saliva production and oral health.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to add moisture to the air.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to support recovery.
🧘
Practice good hand hygiene to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have a fever or feel weak. Light activity like walking may be beneficial, but consult your doctor before resuming intense workouts.

🥗 Diet Recommendations

Drink warm fluids like herbal tea and soup.
Include vitamin C-rich fruits and vegetables.
Avoid cold and sugary drinks that can thicken mucus.
Eat light, easily digestible meals.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to rest and recover fully before returning to work.

🛑 When to Stop This Medicine

Stop taking this medicine if your cough persists for more than 7 days, or if you develop a fever, rash, or difficulty breathing. Consult your doctor before stopping if you are on a prescribed course.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to electrolyte imbalance or gastrointestinal disturbances. Regular monitoring of liver and kidney function may be advised if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal irrigation

Can help clear nasal passages and reduce postnasal drip.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, consult your doctor before vaccination if you are unwell.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, continue your regular dosing schedule as prescribed. Check customs regulations for carrying medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with acute bronchitis
Started this medicine as prescribed for productive cough. Within 3 days noticed significant improvement in chest congestion and easier expectoration. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old with COPD exacerbation
Used this medicine as part of COPD management. Helped clear mucus and improve breathing. Reminded to stay hydrated and avoid alcohol.
💡 Lesson: This medicine can be beneficial in COPD but should be used under medical supervision.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes to 1 hour, but you may notice significant relief in 2-3 days.

Q: Can I take it with other cold medicines?

A: Consult your doctor before combining with other cold medicines, as some may interact.

Q: Is it safe for children?

A: It is not recommended for children under 12 years without medical advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for qril tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: It is only effective for productive cough with mucus. It is not for dry cough.
  • Myth: It is safe to take for long periods.
    Fact: It should not be used for more than 7 days without medical advice.
  • Myth: It can be taken without water.
    Fact: It should be taken with plenty of water to help loosen mucus.

🔄 Alternative Options

Generic Alternatives

  • Guaifenesin + Bromhexine combination tablets from other manufacturers.

Brand Alternatives

  • Leekuf Tablet (this medicine)
  • Other brands containing Guaifenesin and Bromhexine.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Guaifenesin 100 mg + Bromhexine 8 mg","class":"Expectorant + Mucolytic","primary_use":"Productive cough"},{"medicine":"Ambroxol","composition":"Ambroxol","class":"Mucolytic","primary_use":"Productive cough"},{"medicine":"Acetylcysteine","composition":"Acetylcysteine","class":"Mucolytic","primary_use":"Productive cough"}]

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