Gasotin 1mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Irregular or rapid heartbeat, palpitations, or fainting
- Severe allergic reaction with swelling of face, lips, tongue, or throat, or difficulty breathing
- Involuntary movements of the face, tongue, or limbs
- Severe abdominal pain, blood in vomit, or black tarry stools
- High fever with muscle rigidity, confusion, or irregular pulse
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
If experiencing severe symptoms, call emergency services immediately.
What is progit 1mg tablet used for?
This medicine is a prokinetic tablet containing cinitapride 1 mg. It is used to treat functional dyspepsia and related motility disorders by improving stomach emptying and reducing symptoms like bloating, fullness, and nausea. It is taken orally before meals, usually two to three times daily, as prescribed by a doctor.
- Generic Name: Cinitapride (1mg)
- Manufacturer: Micro Labs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 progit 1mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सिनिटाप्राइड 1 मिलीग्राम की एक प्रोकाइनेटिक गोली है जो पेट और आंतों की गति को सुधारने में मदद करती है। इसका उपयोग मुख्य रूप से कार्यात्मक अपच (फंक्शनल डिस्पेप्सिया) के लक्षणों जैसे भोजन के बाद पेट भरा हुआ महसूस होना, जल्दी पेट भर जाना, पेट में सूजन, मतली और ऊपरी पेट में असुविधा को कम करने के लिए किया जाता है। यह दवा पेट से भोजन को छोटी आंत में जल्दी पहुंचाने में मदद करती है। यह डॉक्टर के पर्चे पर ही ली जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, पेट दर्द, दस्त और मतली शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। दुर्लभ मामलों में दिल की धड़कन अनियमित हो सकती है, गंभीर एलर्जी हो सकती है, या चेहरे और जीभ में अनैच्छिक हरकतें हो सकती हैं। अगर कोई भी लक्षण लंबे समय तक बना रहे या गंभीर हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। इसे भोजन से 15-30 मिनट पहले लेना सबसे अच्छा होता है। इस दवा के साथ शराब न पिएं क्योंकि इससे चक्कर और नींद आ सकती है। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं, खासकर दिल की धड़कन, अवसाद या संक्रमण की दवाएं। अगर आपको लीवर या किडनी की समस्या है, तो डॉक्टर को बताएं। इस दवा को बच्चों से दूर रखें और ठंडी, सूखी जगह पर स्टोर करें।
💊 progit 1mg tablet Uses & Benefits
[{"condition":"Functional dyspepsia","description":"Relieves postprandial fullness, early satiety, and upper abdominal discomfort by improving gastric emptying and gut motility.","evidence":"Well-established"},{"condition":"Gastroesophageal reflux disease (GERD) adjunct","description":"May be used alongside acid-suppressing medicines to reduce reflux episodes by enhancing lower esophageal sphincter tone and gastric clearance.","evidence":"Moderate"},{"condition":"Diabetic gastroparesis","description":"Helps improve symptoms of delayed stomach emptying in some patients with diabetes, though evidence is limited.","evidence":"Limited"},{"condition":"Nausea and vomiting associated with motility disorders","description":"Provides symptomatic relief by promoting coordinated gastrointestinal movement.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Irritable bowel syndrome (IBS) with constipation","description":"Occasionally prescribed off-label to improve bowel movement frequency and reduce bloating.","evidence":"Limited"},{"condition":"Post-operative ileus","description":"Rarely used off-label to stimulate bowel motility after surgery, but evidence is insufficient.","evidence":"Insufficient"}]
Primary treatment for: Functional dyspepsia
Also treats: Gastroesophageal reflux disease (GERD), Diabetic gastroparesis, Nausea and vomiting associated with motility disorders
📋 Drug Information
| Generic Name(s) | Cinitapride (1mg) |
| Brand Name | progit 1mg tablet |
| Manufacturer | Micro Labs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Serotonin (5-HT4) receptor agonist-Prokinetic agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the tablets in their original container, tightly closed. Do not store in the bathroom. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture. Do not use beyond the expiry date printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by selectively stimulating serotonin 5-HT4 receptors located in the gastrointestinal tract. Activation of these receptors enhances the release of acetylcholine from enteric neurons, which in turn increases the strength and coordination of contractions in the stomach and intestines. This leads to faster gastric emptying, improved antroduodenal coordination, and reduced reflux of stomach contents into the esophagus. Additionally, it may have mild antiemetic effects by modulating 5-HT3 receptors, although this action is less prominent. The overall result is improved movement of food through the digestive system and relief from symptoms such as bloating, fullness, and nausea.
Mechanism Steps
💡 How to Take progit 1mg tablet
Strength: Cinitapride 1 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1 mg taken orally two to three times daily, preferably 15 to 30 minutes before meals. The exact dose and frequency depend on the condition being treated and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. Follow your doctor's instructions carefully. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and cardiac effects. A lower starting dose may be considered, and close monitoring is advised. Dose must be individualized by a qualified clinician based on renal and hepatic function and concomitant medications. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually necessary. In severe renal impairment, this medicine should be used with caution, and a dose reduction may be considered. Consult your doctor for personalized advice. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no dose adjustment is typically required. In severe hepatic impairment, the clearance of this medicine may be reduced, and a lower dose may be necessary. Close monitoring for side effects is recommended. Consult your doctor for personalized advice. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 mg (1 mg three times daily). Do not exceed this dose unless specifically instructed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of progit 1mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | |
| Ketoconazole | Major | |
| Atropine | Moderate | |
| Morphine | Moderate | |
| Metoprolol | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Moderate | |
| Alcohol | Moderate | |
| Fluoxetine | Moderate | |
| Warfarin | Minor |
🚨 Major Interactions
- QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)
- Monoamine oxidase inhibitors (MAOIs)
- Potent CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin, ritonavir)
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, hyoscyamine)
- Opioid analgesics
- Beta-blockers
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and impaired coordination when taken with this medicine. It is advisable to avoid alcohol or limit its intake while on this medicine. Alcohol can also worsen gastrointestinal symptoms such as nausea and abdominal discomfort.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to cinitapride or any component of the tablet","Gastrointestinal bleeding, mechanical obstruction, or perforation","History of QT interval prolongation or congenital long QT syndrome","Severe cardiac disease such as recent myocardial infarction or heart failure","Concomitant use with potent QT-prolonging drugs","Pregnancy and breastfeeding unless clearly needed and advised by a doctor"]
⚠️ Warnings & Precautions
["Use with caution in patients with liver or kidney disease; dose adjustment may be needed.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine as it can increase drowsiness and dizziness.","Inform your doctor if you have a history of heart rhythm problems or are taking other medicines that affect heart rhythm.","Do not exceed the recommended dose; higher doses may increase the risk of side effects.","If you experience involuntary movements of the face or tongue, stop the medicine and contact your doctor immediately.","This medicine may interact with other drugs; always provide a complete list of your medications to your healthcare provider."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human breast milk. Because many medicines are excreted in breast milk, caution should be exercised when this medicine is administered to a nursing woman. Consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose of this medicine may cause severe drowsiness, dizziness, nausea, vomiting, and irregular heartbeat. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including monitoring of vital signs and cardiac rhythm. There is no specific antidote. Gastric lavage may be considered if the overdose is recent and the patient is stable. Contact a poison control center for guidance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water, preferably before meals to help it work effectively. Do not crush, chew, or break the tablet unless your doctor instructs you to do so. Avoid drinking alcohol while taking this medicine because it can worsen dizziness and drowsiness. Inform your doctor about all other medicines you are taking, especially those for heart rhythm problems, depression, or infections, as some may interact with this medicine. If you have liver or kidney problems, your doctor may need to adjust your dose or monitor you more closely. Do not share this medicine with anyone else, even if they have similar symptoms. Keep this medicine out of the reach of children and store it in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, particularly dizziness, drowsiness, and cardiac effects. A lower starting dose may be considered, and close monitoring is advised. Regular assessment of kidney and liver function is recommended. Falls risk should be evaluated if dizziness occurs.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the potential benefits against the risks and may recommend alternative treatments. Use effective contraception if advised.
🏥 Post-Surgery Considerations
This medicine may be used after surgery to stimulate bowel motility if approved by your surgeon. However, it should be used with caution in the immediate post-operative period, especially after gastrointestinal surgery, due to the risk of anastomotic leakage. Always follow your surgeon's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific contraindications, but if you experience dizziness or drowsiness, it may affect your ability to undergo certain procedures. Your dentist may advise you to take the medicine as usual unless instructed otherwise.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness in some people. Avoid strenuous exercise or activities that require balance until you know how the medicine affects you. Light to moderate exercise is generally safe and can aid digestion.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some individuals. If affected, avoid driving, operating heavy machinery, or performing tasks that require alertness. Most people can continue their normal daily activities, but it is important to assess your response to the medicine. Inform your employer if your job involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as irregular heartbeat, severe allergic reaction, or involuntary movements, stop the medicine and seek immediate medical attention. Your doctor will advise you on whether to continue, adjust the dose, or switch to an alternative treatment.
📅 Long-Term Use Effects
Long-term use of this medicine should be monitored by a doctor. There is a potential risk of tardive dyskinesia with prolonged use, although rare. Regular assessment of symptoms and periodic monitoring of heart rhythm and liver function may be advised. If you experience any involuntary movements, stop the medicine and consult your doctor immediately. Do not use for longer than prescribed without medical review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating smaller, low-fat meals and avoiding trigger foods can help manage dyspepsia symptoms.
Evidence: Well-establishedTechniques like yoga, meditation, and deep breathing can reduce stress-related digestive symptoms.
Evidence: ModerateMedicines like domperidone or levosulpiride may be alternatives if this medicine is not suitable.
Evidence: Well-establishedSome studies suggest acupuncture may help with functional dyspepsia, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, always inform your healthcare provider about all medicines you are taking before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, adjust your dosing schedule to maintain approximately equal intervals between doses, but consult your doctor for specific advice. Keep enough supply for your entire trip and carry it in your hand luggage to avoid loss. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose. However, full symptomatic relief may take several days of regular use.
A: It is best taken 15 to 30 minutes before meals to enhance its prokinetic effect. Taking it with food may reduce its effectiveness.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Long-term use should be under the supervision of a doctor. Regular monitoring may be needed, especially for heart rhythm and liver function.
A: It is advisable to avoid alcohol as it can increase dizziness, drowsiness, and gastrointestinal side effects.
🤔 Common Patient Concerns
🔄 Substitutes for progit 1mg tablet
View AllAlternative brands with exact same active ingredient:
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cintaflux 1mg tabletMankind Pharma Ltd ₹35.72 41.4% CHEAPER
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biopride 1mg tabletLividus Pharmaceuticals Pvt Ltd ₹37.38 38.7% CHEAPER
-
acepride 1mg tabletAcekinetics Healthcare Pvt Ltd ₹45.94 24.6% CHEAPER
-
cinmove 1mg tabletCipla Ltd ₹56.25 7.7% CHEAPER
-
cintazide 1mg tabletInnovative Pharmaceuticals ₹56.25 7.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all stomach problems.
Fact: This medicine is specifically for motility-related disorders and is not effective for all gastrointestinal conditions. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You should complete the prescribed course and consult your doctor before stopping, as symptoms may return. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: Taking a double dose will make it work faster.
Fact: Taking more than the prescribed dose can increase the risk of side effects and does not improve efficacy.
🔄 Alternative Options
Generic Alternatives
- Cinitapride 1 mg tablet (various manufacturers)
Brand Alternatives
- Gasotin 1mg Tablet