Enzoflam Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is powerflam xp 50 mg/325 mg tablet used for?
This medicine is a combination of Diclofenac 50 mg and Paracetamol 325 mg used for short-term relief of pain and inflammation. It is taken orally with food, usually two to three times daily, and should not be used for more than a few days without medical advice.
- Generic Name: Diclofenac (50mg) + Paracetamol (325mg)
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 powerflam xp 50 mg/325 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डाइक्लोफेनाक 50 मिलीग्राम और पैरासिटामोल 325 मिलीग्राम का संयोजन है, जिसका उपयोग दर्द और सूजन से राहत के लिए किया जाता है। यह जोड़ों के दर्द, मांसपेशियों के दर्द, दांत दर्द, मासिक धर्म के दर्द और बुखार में प्रभावी है। इसे भोजन के साथ लेना चाहिए और डॉक्टर की सलाह के बिना लंबे समय तक नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, गुर्दे की समस्या, यकृत विषाक्तता और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की समस्या हो सकती है। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें। यदि आपको पेट अल्सर, गुर्दे या यकृत की बीमारी, हृदय रोग या अस्थमा है तो डॉक्टर को बताएं। गर्भावस्था के तीसरे तिमाही में इसका उपयोग न करें।
💊 powerflam xp 50 mg/325 mg tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Provides short-term relief for strains, sprains, and back pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Manages mild to moderate pain following surgical procedures.","evidence":"Well-established"},{"condition":"Dental pain","description":"Relieves pain associated with toothache, extraction, or dental procedures.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Reduces menstrual cramps and associated pain.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Bursitis","description":"May be used off-label for pain relief in bursitis.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Musculoskeletal pain, Dental pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Diclofenac (50mg) + Paracetamol (325mg) |
| Brand Name | powerflam xp 50 mg/325 mg tablet |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Diclofenac, an NSAID, reversibly inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, leading to decreased synthesis of prostaglandins, prostacyclin, and thromboxane. This results in reduced inflammation, pain, and fever. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesia and antipyresis with minimal anti-inflammatory effects. Together, they provide enhanced pain relief through different pathways.
Mechanism Steps
💡 How to Take powerflam xp 50 mg/325 mg tablet
Strength: Tablet containing Diclofenac 50 mg and Paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet two to three times daily, depending on the severity of pain and the prescribing doctor's advice. The maximum daily dose should not exceed three tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate or exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are at higher risk of side effects, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose reduction or avoidance may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose reduction or avoidance may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | Maximum daily dose: Diclofenac 150 mg and Paracetamol 975 mg (three tablets) in 24 hours. Do not exceed. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of powerflam xp 50 mg/325 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Methotrexate | Major | |
| ACE inhibitors | Major | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- Methotrexate
- ACE inhibitors
⚡ Moderate Interactions
- Diuretics
- Corticosteroids
- SSRIs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity, especially with paracetamol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to diclofenac, paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Active peptic ulcer or gastrointestinal bleeding.","Severe heart failure, ischemic heart disease, or peripheral arterial disease.","Severe kidney impairment (eGFR
⚠️ Warnings & Precautions
["Take with food or milk to reduce stomach upset.","Avoid alcohol while taking this medicine.","Do not exceed the recommended dose or duration.","Use with caution in the elderly.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma.","Do not take other NSAIDs or paracetamol-containing products simultaneously.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Consult your doctor if symptoms persist beyond 7 days."]
🤱 Lactation Safety
Diclofenac and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose can cause severe liver damage from paracetamol and gastrointestinal bleeding, kidney failure, and central nervous system effects from diclofenac. Seek immediate medical attention. Treatment includes activated charcoal, N-acetylcysteine for paracetamol toxicity, and supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding and liver damage. Do not take other NSAIDs or paracetamol-containing products simultaneously to prevent overdose. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Use with caution in the elderly. Do not use during the third trimester of pregnancy. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose. Do not double the dose. Store in a cool, dry place away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration and monitor closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy if you are taking this medicine. It is not recommended during the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain, but consult your surgeon before use as it may increase bleeding risk.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while taking this medicine as it may increase the risk of bleeding or injury. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, kidney problems, or allergic reactions. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of kidney and liver function is recommended. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help relieve localized pain and inflammation.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. Consult your doctor before vaccination if you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid exposure to extreme heat or moisture. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30-60 minutes after taking the tablet.
A: It is best taken with food or milk to reduce stomach upset.
A: Long-term use should be under medical supervision due to risks of kidney, liver, and gastrointestinal side effects.
🤔 Common Patient Concerns
🔄 Substitutes for powerflam xp 50 mg/325 mg tablet
View AllAlternative brands with exact same active ingredient:
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dolopee tabletAgron Remedies Pvt Ltd ₹4.26 4.3% CHEAPER
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neurogesic tabletTorque Pharmaceuticals Pvt Ltd ₹4.39 1.3% CHEAPER
-
azet plus 50 mg/325 mg tabletMoraceae Pharmaceuticals Pvt Ltd ₹4.78 7.4% COSTLIER
-
dpc tabletTorque Pharmaceuticals Pvt Ltd ₹5.00 12.4% COSTLIER
-
relief tabletLaborate Pharmaceuticals India Ltd ₹6.25 40.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach upset. - Myth: It is safe to take this medicine for long periods without monitoring.
Fact: Long-term use requires monitoring of kidney and liver function. - Myth: This medicine is safe for everyone.
Fact: It is contraindicated in certain conditions like peptic ulcer and severe kidney disease.
🔄 Alternative Options
Generic Alternatives
- Diclofenac 50 mg + Paracetamol 325 mg tablet
Brand Alternatives
- Enzoflam Tablet