Hifenac Spas Tablet: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
- Severe skin rash with blisters or peeling
- Persistent high fever
If experiencing severe symptoms, call emergency services immediately.
What is polydol spas 80mg/100mg tablet used for?
This medicine is a combination of Drotaverine (80 mg) and Aceclofenac (100 mg) used to relieve pain and spasm in conditions like abdominal cramps, menstrual pain, and biliary or renal colic. It works by relaxing smooth muscles and reducing inflammation. It should be taken with food and only as prescribed by a doctor.
- Generic Name: Drotaverine (80mg) + Aceclofenac (100mg)
- Manufacturer: Curewin Hylico Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 polydol spas 80mg/100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ड्रोटावेरिन 80 मिलीग्राम और एसिक्लोफेनाक 100 मिलीग्राम का संयोजन है। इसका उपयोग पेट की ऐंठन, मासिक धर्म के दर्द, पित्ताशय की ऐंठन और गुर्दे की ऐंठन जैसी स्थितियों में दर्द और ऐंठन को कम करने के लिए किया जाता है। यह मांसपेशियों को आराम देकर और सूजन को कम करके काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, यकृत विषाक्तता और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको काला मल, खून की उल्टी, गंभीर पेट दर्द, पेशाब में कमी, आंखों या त्वचा का पीलापन, या असामान्य रक्तस्राव दिखे तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक या अवधि से अधिक न लें। पेट की जलन से बचने के लिए इसे भोजन या दूध के साथ लें। इस दवा के साथ शराब न लें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको चक्कर या नींद आती है तो वाहन न चलाएं। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 polydol spas 80mg/100mg tablet Uses & Benefits
[{"condition":"Abdominal cramps and spasms","description":"Relieves smooth muscle spasm in the gastrointestinal tract, reducing pain and discomfort.","evidence":"Well-established"},{"condition":"Primary dysmenorrhea","description":"Reduces menstrual cramps and associated pain through antispasmodic and anti-inflammatory actions.","evidence":"Well-established"},{"condition":"Biliary colic","description":"Helps relieve spasm of the biliary tract, reducing pain associated with gallstones or biliary dyskinesia.","evidence":"Moderate"},{"condition":"Renal colic","description":"Used to relieve pain from ureteral spasm, often as an adjunct to other treatments.","evidence":"Moderate"},{"condition":"Post-operative pain with spasm","description":"May be used for short-term management of pain involving smooth muscle spasm after surgery.","evidence":"Limited"}]
Off-label uses: [{"condition":"Irritable bowel syndrome (IBS) pain","description":"Sometimes prescribed to relieve cramping and pain in IBS, though not a standard treatment.","evidence":"Limited"},{"condition":"Pelvic inflammatory disease (PID) pain","description":"May be used as an adjunct for pain relief in PID, but antibiotics are the primary treatment.","evidence":"Limited"}]
Primary treatment for: Painful smooth muscle spasm
Also treats: Dysmenorrhea, Biliary colic, Renal colic, Gastrointestinal spasm, Post-operative pain
📋 Drug Information
| Generic Name(s) | Drotaverine (80mg) + Aceclofenac (100mg) |
| Brand Name | polydol spas 80mg/100mg tablet |
| Manufacturer | Curewin Hylico Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container to protect from light. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Drotaverine is a selective phosphodiesterase-4 inhibitor that increases cyclic adenosine monophosphate (cAMP) levels in smooth muscle cells, leading to relaxation and relief of spasm. Aceclofenac is a nonsteroidal anti-inflammatory drug that inhibits cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby decreasing pain and inflammation. Together, they address both the spasm and the inflammatory components of pain.
Mechanism Steps
💡 How to Take polydol spas 80mg/100mg tablet
Strength: Tablet containing Drotaverine 80 mg and Aceclofenac 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally one to two times daily, preferably with food. The exact dose and duration depend on the condition being treated and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. For acute pain, it is typically used for short periods. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal and renal side effects. Use with caution and at the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. In severe renal impairment (creatinine clearance <30 mL/min), this medicine is contraindicated. Consult your doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. In severe hepatic impairment, this medicine is contraindicated. Consult your doctor for dose adjustment. |
| Maximum Daily Dose | The maximum recommended daily dose is two tablets (Drotaverine 160 mg + Aceclofenac 200 mg) per day. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of polydol spas 80mg/100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| SSRIs | Moderate | |
| Digoxin | Moderate | |
| Cyclosporine | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- Antihypertensives (ACE inhibitors, ARBs, diuretics)
- SSRIs
- Digoxin
- Cyclosporine
- Tacrolimus
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Both drotaverine and aceclofenac can cause dizziness and drowsiness, and alcohol can amplify these effects. Additionally, alcohol increases the risk of gastrointestinal bleeding and liver toxicity associated with aceclofenac. If you consume alcohol regularly, discuss this with your doctor before taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to drotaverine, aceclofenac, or any component of the formulation","Active or history of recurrent peptic ulcer or gastrointestinal bleeding","Severe heart failure, ischemic heart disease, or peripheral arterial disease","Severe hepatic impairment","Severe renal impairment (creatinine clearance
⚠️ Warnings & Precautions
["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption as it increases the risk of stomach bleeding and liver toxicity.","Do not drive or operate machinery if you experience dizziness or drowsiness.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma.","Do not use for prolonged periods without medical supervision.","If you are pregnant or breastfeeding, consult your doctor before use.","Do not take other NSAIDs or pain relievers concurrently without medical advice.","Report any signs of bleeding, bruising, or persistent stomach pain to your doctor.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether drotaverine and aceclofenac are excreted in human breast milk. Because many drugs are excreted in breast milk and due to potential serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause symptoms such as severe nausea, vomiting, stomach pain, dizziness, drowsiness, and potentially gastrointestinal bleeding or kidney damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if the patient presents early. Monitor vital signs, renal function, and liver function. Activated charcoal may be administered if appropriate.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it can increase the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Do not take other pain relievers or NSAIDs without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events with NSAIDs. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. Avoid concurrent use with other NSAIDs or anticoagulants. Consult your doctor for dose adjustments.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs like aceclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Drotaverine is also not recommended during pregnancy unless clearly needed. Discuss alternative pain management options with your doctor.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used for short-term pain relief if prescribed by your surgeon. However, it may increase the risk of bleeding and interfere with wound healing. Inform your surgeon if you are taking this medicine before any surgery. Do not self-medicate after surgery without medical advice.
🦷 Dental Procedures
If you are scheduled for dental work, inform your dentist that you are taking this medicine. It may increase the risk of bleeding during procedures. Your dentist may advise you to stop the medicine temporarily before certain procedures. Do not stop without consulting your prescribing doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require high coordination until you know how the medicine affects you. If you have pain, gentle stretching and low-impact exercises may be beneficial, but consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. If your work involves physical labor, take precautions to avoid injury. Discuss with your doctor if your job requires high alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience any serious side effects such as black or tarry stools, vomiting blood, severe abdominal pain, allergic reactions, decreased urine output, or yellowing of skin or eyes. Do not stop taking it abruptly if you have been on long-term therapy without consulting your doctor, as some effects may need monitoring.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of serious gastrointestinal, cardiovascular, and renal adverse effects. It may cause stomach ulcers, bleeding, kidney impairment, and liver toxicity. Regular monitoring of kidney and liver function, blood counts, and blood pressure is recommended for prolonged use. It is generally not intended for long-term use without periodic reassessment by a doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and muscle spasm.
Evidence: Well-establishedApplying heat to the affected area can help relax muscles and relieve spasm.
Evidence: ModerateMay help reduce pain and muscle tension in some individuals.
Evidence: LimitedDeep breathing, meditation, and yoga can help reduce muscle tension and pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor that you are taking this medicine, as NSAIDs may slightly affect immune response. Generally, it is safe to receive vaccines while on this medicine, but consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, continue taking it at the same intervals as prescribed; adjust timing gradually. Check local customs regulations regarding prescription medicines. Always keep it in your carry-on luggage if flying. Do not expose to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the tablet, with antispasmodic effects starting within 15 to 30 minutes.
A: It is best taken with food or milk to reduce the risk of stomach upset and ulcers.
A: It is generally avoided during pregnancy, especially in the third trimester. Consult your doctor for individualized advice.
A: No, alcohol should be avoided as it increases the risk of gastrointestinal bleeding and liver toxicity.
A: It is usually prescribed for short-term use. Do not take it for more than 7 days without consulting your doctor.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not take other NSAIDs or pain relievers concurrently without medical advice, as it may increase the risk of side effects.
A: Use with caution in kidney disease. In severe renal impairment, it is contraindicated. Consult your doctor for dose adjustment.
🤔 Common Patient Concerns
🔄 Substitutes for polydol spas 80mg/100mg tablet
View AllAlternative brands with exact same active ingredient:
-
drona 80 mg/100 mg injectionBennet Pharmaceuticals Limited ₹10.31 86.3% CHEAPER
-
dynamet a 80mg/100mg tabletCubit Healthcare ₹42.19 43.7% CHEAPER
-
stayhappi drotaverine+aceclofenac 80mg/100mg tabletSarvagunaushdhi Pvt Ltd ₹46.88 37.5% CHEAPER
-
termispaz d 80 mg/100 mg tabletResilient Cosmecueticals Pvt Ltd ₹51.56 31.3% CHEAPER
-
drona 80 mg/100 mg tabletThemis Medicare Ltd ₹52.37 30.2% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: It is specifically for pain associated with smooth muscle spasm and inflammation. It is not effective for all types of pain. - Myth: It is safe to take this medicine long-term without monitoring.
Fact: Prolonged use can cause serious side effects like stomach bleeding, kidney problems, and liver toxicity. Regular monitoring is required. - Myth: You can take this medicine on an empty stomach.
Fact: It should be taken with food to reduce the risk of stomach upset and ulcers. - Myth: It is safe to take during pregnancy.
Fact: It is generally avoided during pregnancy, especially in the third trimester, due to potential risks to the fetus. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol increases the risk of gastrointestinal bleeding and liver toxicity. It should be avoided.
🔄 Alternative Options
Generic Alternatives
- Drotaverine + Aceclofenac tablet (various manufacturers)
Brand Alternatives
- Hifenac Spas Tablet