Neogra-X 100mg/60mg Super Force Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Erection lasting more than 4 hours (priapism)
- Sudden vision loss or blurred vision
- Sudden hearing decrease or ringing in the ears
- Chest pain, shortness of breath, or palpitations
- Fainting or severe dizziness
- Signs of serotonin syndrome: agitation, confusion, rapid heart rate, fever, muscle twitching
- Swelling of the face, lips, tongue, or throat
- Severe headache with visual changes
If experiencing severe symptoms, call emergency services immediately.
What is penetal 100mg/60mg tablet used for?
This medicine is a prescription-only tablet containing sildenafil 100 mg and dapoxetine 60 mg. It is used in adult men to treat erectile dysfunction and premature ejaculation together. It works by increasing blood flow to the penis and delaying ejaculation. It should be taken about 1 to 3 hours before sexual activity, not more than once in 24 hours, and must be avoided with nitrates, alcohol, and certain other medicines.
- Generic Name: Sildenafil (100mg) + Dapoxetine (60mg)
- Manufacturer: Zydus Cadila
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 penetal 100mg/60mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सिल्डेनाफिल 100 मिलीग्राम और डैपोक्सेटीन 60 मिलीग्राम का संयोजन है, जिसका उपयोग वयस्क पुरुषों में स्तंभन दोष (इरेक्टाइल डिसफंक्शन) और शीघ्रपतन (प्रीमैच्योर इजैकुलेशन) के इलाज के लिए किया जाता है। सिल्डेनाफिल लिंग में रक्त के प्रवाह को बढ़ाकर स्तंभन प्राप्त करने और बनाए रखने में मदद करता है, जबकि डैपोक्सेटीन मस्तिष्क में सेरोटोनिन के स्तर को बढ़ाकर स्खलन में देरी करता है। यह दवा यौन उत्तेजना के बिना काम नहीं करती और इसे केवल डॉक्टर की सलाह पर ही लेना चाहिए। इसे यौन गतिविधि से लगभग 1 से 3 घंटे पहले लिया जाता है और 24 घंटे में एक बार से अधिक नहीं लेना चाहिए। शराब, नाइट्रेट्स और कुछ अन्य दवाओं के साथ इसका सेवन खतरनाक हो सकता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, चेहरे पर लालिमा, नाक बंद होना, जी मिचलाना, मुँह सूखना और अपच शामिल हैं। गंभीर दुष्प्रभावों में दृष्टि का अचानक चले जाना, सुनने में कमी, लंबे समय तक बने रहने वाला दर्दनाक स्तंभन (प्रियापिज्म), बेहोशी और सेरोटोनिन सिंड्रोम शामिल हैं। यदि आपको 4 घंटे से अधिक समय तक स्तंभन बना रहता है, अचानक दृष्टि या सुनने में बदलाव होता है, या सीने में दर्द होता है, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। यौन गतिविधि से 1 से 3 घंटे पहले एक गोली पूरे पानी के साथ निगलें। 24 घंटे में एक से अधिक गोली न लें। शराब का सेवन बिल्कुल न करें क्योंकि इससे चक्कर आना, निम्न रक्तचाप और स्तंभन दोष बढ़ सकता है। नाइट्रेट्स या नाइट्रिक ऑक्साइड डोनर के साथ इसका सेवन न करें। अपने डॉक्टर को अपनी सभी दवाओं के बारे में बताएं। जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है, तब तक वाहन न चलाएं। यदि आपको 4 घंटे से अधिक समय तक स्तंभन बना रहता है, बेहोशी आती है, या सीने में दर्द होता है, तो तुरंत चिकित्सा सहायता लें।
💊 penetal 100mg/60mg tablet Uses & Benefits
- [{"condition":"Erectile Dysfunction (ED)","description":"This medicine helps men with erectile dysfunction achieve and maintain an erection sufficient for sexual activity when sexual stimulation is present.
- Sildenafil increases penile blood flow by inhibiting PDE5.","evidence":"Well-established for sildenafil component"},{"condition":"Premature Ejaculation (PE)","description":"This medicine helps delay ejaculation and improves control over ejaculation, reducing distress and improving sexual satisfaction.
- Dapoxetine, an SSRI, is the component responsible for this effect.","evidence":"Well-established for dapoxetine component"},{"condition":"Concurrent ED and PE","description":"This fixed-dose combination is intended for adult men who have both erectile dysfunction and premature ejaculation, as diagnosed by a clinician.
- It addresses both conditions with a single tablet.","evidence":"Combination use supported by clinical experience; individual components well-established"}]
Off-label uses: [{"condition":"Pulmonary arterial hypertension","description":"Sildenafil alone is approved for pulmonary arterial hypertension, but this combination product is not intended for that use.","evidence":"Well-established for sildenafil alone, not for this combination"},{"condition":"Raynaud's phenomenon","description":"Sildenafil has been studied off-label for Raynaud's phenomenon, but this combination is not recommended for that purpose.","evidence":"Limited"}]
Primary treatment for: Erectile Dysfunction and Premature Ejaculation
Also treats: Sexual dysfunction associated with diabetes mellitus, Sexual dysfunction associated with hypertension, Sexual dysfunction associated with psychological factors
📋 Drug Information
| Generic Name(s) | Sildenafil (100mg) + Dapoxetine (60mg) |
| Brand Name | penetal 100mg/60mg tablet |
| Manufacturer | Zydus Cadila |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | SEX STIMULANTS REJUVENATORS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight, moisture, and heat. Do not refrigerate unless specified. Keep in the original container to protect from light and moisture. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. The World Health Organization does not provide specific guidelines for this fixed-dose combination product. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research does not provide specific guidelines for this fixed-dose combination product. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). During sexual stimulation, nitric oxide is released in the corpus cavernosum, which increases cGMP and causes smooth muscle relaxation and increased blood flow into the penis. Sildenafil prevents the breakdown of cGMP, thereby enhancing and prolonging erection. Dapoxetine is a selective serotonin reuptake inhibitor (SSRI) that increases serotonin levels in the synaptic cleft, which modulates the ejaculatory reflex and delays ejaculation. Together, these actions address erectile dysfunction and premature ejaculation respectively.
Mechanism Steps
💡 How to Take penetal 100mg/60mg tablet
Strength: Tablet containing sildenafil 100 mg and dapoxetine 60 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally about 1 to 3 hours before anticipated sexual activity. Do not take more than one tablet in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and other medications. This medicine is not recommended for men over 65 years of age without medical evaluation. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not for use in children or adolescents under 18 years of age. Consult a pediatrician for any concerns. |
| Elderly Dosage | This medicine is not recommended for men over 65 years of age without a thorough medical evaluation. Elderly patients may be more sensitive to the effects of sildenafil and dapoxetine, including dizziness, low blood pressure, and fainting. Dose adjustment and close monitoring are required if prescribed. |
| Renal Impairment | In patients with mild to moderate renal impairment, no dose adjustment is usually needed. In severe renal impairment, dapoxetine clearance may be reduced, and this medicine should be used with caution. Dose adjustment may be necessary as advised by a clinician. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, this medicine should be used with caution, and dose adjustment may be needed. This medicine is contraindicated in severe hepatic impairment. |
| Maximum Daily Dose | One tablet in 24 hours. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of penetal 100mg/60mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Nitrates | Major | |
| MAOIs | Major | |
| Thioridazine | Major | |
| Strong CYP3A4 inhibitors | Major | |
| Other serotonergic drugs | Major | |
| Alpha-blockers | Major | |
| Moderate CYP3A4 inhibitors | Moderate | |
| CYP2D6 inhibitors | Moderate | |
| Antihypertensives | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
- Monoamine oxidase inhibitors (MAOIs)
- Thioridazine
- Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
- Other serotonergic drugs (e.g., SSRIs, SNRIs, triptans, tramadol)
- Alpha-blockers (e.g., doxazosin, tamsulosin)
⚡ Moderate Interactions
- Moderate CYP3A4 inhibitors (e.g., erythromycin, grapefruit juice)
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- Antihypertensives
- Alcohol
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Alcohol can increase the risk of dizziness, drowsiness, and low blood pressure caused by sildenafil and dapoxetine. It can also worsen erectile dysfunction and reduce the effectiveness of the medicine. Combining alcohol with this medicine may also increase the risk of fainting and impaired judgement.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Concomitant use of nitrates or nitric oxide donors","Concomitant use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI","Concomitant use of thioridazine","Severe hepatic impairment","Severe renal impairment","Uncontrolled hypertension or hypotension","History of syncope or fainting","Severe cardiovascular disorders (e.g., unstable angina, recent myocardial infarction, severe heart failure)","Known hypersensitivity to sildenafil, dapoxetine, or any component of the formulation","Men under 18 years of age","Women, including pregnant or breastfeeding women"]
⚠️ Warnings & Precautions
["This medicine is for adult men only and should not be used by women or children.","Do not take this medicine with nitrates or nitric oxide donors, as it can cause a dangerous drop in blood pressure.","Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure.","Do not drive or operate heavy machinery until you know how this medicine affects you.","Seek immediate medical help if you experience an erection lasting more than 4 hours.","Report any sudden vision or hearing changes to your doctor immediately.","Tell your doctor about all other medicines, especially antidepressants, antifungals, and antibiotics.","Use with caution in patients with a history of seizures, mood disorders, or bleeding disorders.","Do not share this medicine with others, even if they have similar symptoms.","Keep this medicine out of the reach of children."]
🤱 Lactation Safety
Not applicable. This medicine is intended for adult men only. It is not for use in breastfeeding women.
💊 Overdose Management
Overdose of this medicine may cause severe hypotension, dizziness, fainting, nausea, and serotonin syndrome. There is no specific antidote. Treatment is supportive and symptomatic. If overdose is suspected, seek emergency medical attention immediately. Do not induce vomiting unless instructed by a healthcare professional. Monitor vital signs, blood pressure, and cardiac rhythm. In case of serotonin syndrome, supportive care and possibly cyproheptadine may be considered by a clinician.
⏰ Missed Dose
This medicine is taken on an as-needed basis, usually 1 to 3 hours before anticipated sexual activity. If you miss a dose, take it as soon as you remember if there is still time before sexual activity. Do not take more than one dose in 24 hours. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually about 1 to 3 hours before anticipated sexual activity. Do not take more than one tablet in 24 hours. Swallow the tablet whole with a full glass of water; do not crush or chew it. Avoid alcohol completely while taking this medicine because alcohol can increase dizziness, drowsiness, and low blood pressure, and can worsen erectile dysfunction. Do not take this medicine with nitrates, nitric oxide donors, or recreational drugs such as amyl nitrite, as this can cause a dangerous drop in blood pressure. Tell your doctor about all other medicines, supplements, and herbal products you take, especially antidepressants, antifungals, antibiotics, and blood pressure medicines. Do not drive or operate heavy machinery until you know how this medicine affects you, because it can cause dizziness and blurred vision. If you experience an erection lasting more than 4 hours, seek emergency medical help immediately. If you faint, have chest pain, or notice sudden vision or hearing changes, stop the medicine and contact a doctor right away. Keep this medicine out of the reach of children and store it at room temperature away from moisture and direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not recommended for men over 65 years of age without a thorough medical evaluation. Elderly patients may be more sensitive to the effects of sildenafil and dapoxetine, including dizziness, low blood pressure, and fainting. Dose adjustment and close monitoring are required if prescribed.
🤰 Pregnancy Planning (TTC)
This medicine is for adult men only and is not for use in women. If you are planning a pregnancy with your partner, discuss any concerns with your doctor. This medicine does not affect male fertility, but underlying conditions may need evaluation.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after any surgery, especially cardiac or vascular surgery. It may interact with anaesthetics and other medicines used during surgery. Do not take this medicine without medical clearance after surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anaesthetics and other medicines used during dental work. Your dentist may advise you to stop the medicine temporarily before the procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise immediately after taking this medicine, as it may increase the risk of dizziness and low blood pressure. Stay hydrated during exercise. If you experience chest pain, shortness of breath, or severe dizziness during exercise, stop and seek medical help.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause dizziness, drowsiness, and blurred vision, which may affect your ability to drive or operate heavy machinery. Avoid driving or operating machinery until you know how this medicine affects you. It may also affect your concentration and mood. Plan your activities accordingly and avoid tasks that require full alertness immediately after taking this medicine.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as priapism, sudden vision or hearing changes, severe dizziness, or signs of serotonin syndrome, stop the medicine and seek immediate medical attention. Your doctor may adjust the dose or switch to another medicine based on your response and side effects.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Regular monitoring of blood pressure, heart rate, and mood is recommended. There is a risk of tolerance, dependence, and serotonin syndrome with prolonged use of dapoxetine. Sildenafil may cause long-term visual or hearing changes in rare cases. Do not use this medicine for prolonged periods without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help with psychological factors contributing to erectile dysfunction and premature ejaculation.
Evidence: Well-establishedCan improve ejaculatory control and erectile function.
Evidence: ModerateWeight loss, exercise, and stress reduction can improve sexual function.
Evidence: Well-establishedMechanical devices that can help achieve erection.
Evidence: Well-established for ED💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions or timing considerations for this medicine. However, inform your doctor about all medicines you take before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, take the medicine as needed for sexual activity, but do not exceed one dose in 24 hours. Declare it at customs if required. Keep it in your hand luggage to avoid loss or temperature extremes.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes for erection, but it may take 1 to 3 hours for full effect. Dapoxetine takes about 1 to 2 hours to delay ejaculation.
A: This medicine is taken on an as-needed basis and should not be taken more than once in 24 hours. Daily use requires medical supervision.
A: Common side effects include headache, dizziness, flushing, nasal congestion, nausea, dry mouth, and indigestion. Most are mild and resolve on their own.
A: No, alcohol should be completely avoided as it increases the risk of dizziness, low blood pressure, and can worsen erectile dysfunction.
A: If you miss a dose, take it as soon as you remember if there is still time before sexual activity. Do not take more than one dose in 24 hours.
🤔 Common Patient Concerns
🔄 Substitutes for penetal 100mg/60mg tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is an aphrodisiac and will increase sexual desire.
Fact: This medicine does not increase sexual desire. It requires sexual stimulation to work and helps with erection and ejaculation control. - Myth: This medicine can be taken with alcohol without any problems.
Fact: Alcohol should be avoided completely as it increases the risk of dizziness, low blood pressure, and can worsen erectile dysfunction. - Myth: This medicine is safe to take every day.
Fact: This medicine is taken on an as-needed basis and should not be taken more than once in 24 hours. Daily use requires medical supervision. - Myth: This medicine can be shared with friends who have similar problems.
Fact: This medicine is prescription-only and should never be shared. It can cause serious harm if taken by someone with contraindications. - Myth: This medicine is a permanent cure for erectile dysfunction.
Fact: This medicine provides temporary relief and is not a cure. Lifestyle changes and medical evaluation are important for long-term management.
🔄 Alternative Options
Generic Alternatives
- Sildenafil 100 mg + Dapoxetine 60 mg tablet
Brand Alternatives
- Neogra-X 100mg/60mg Super Force Tablet