Lippod 50mg Injection: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Chest pain or shortness of breath
- Severe allergic reaction (swelling of face, lips, throat)
- Fever, chills, or signs of infection
- Unusual bleeding or bruising
- Pain, redness, or swelling at the infusion site
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is peg-adrim 50mg injection used for?
This medicine is a liposomal form of doxorubicin, a chemotherapy drug used to treat ovarian cancer, AIDS-related Kaposi's sarcoma, and multiple myeloma. It is given intravenously by a healthcare professional and works by interfering with cancer cell growth.
- Generic Name: Doxorubicin (Liposomal) (50mg)
- Manufacturer: Fresenius Kabi India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 peg-adrim 50mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा लिपोसोमल डॉक्सोरूबिसिन का एक इंजेक्शन है, जिसका उपयोग कैंसर के इलाज के लिए किया जाता है। यह मुख्य रूप से डिम्बग्रंथि कैंसर, एड्स से जुड़े कपोसी सारकोमा और मल्टीपल मायलोमा के इलाज में प्रयोग की जाती है। यह दवा कैंसर कोशिकाओं की वृद्धि को रोकती है और उन्हें नष्ट करती है। यह केवल एक योग्य कैंसर विशेषज्ञ द्वारा अस्पताल में ही दी जानी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, भूख न लगना, मुँह के छाले, थकान और रक्त कोशिकाओं की कमी शामिल हैं। गंभीर दुष्प्रभावों में हृदय की क्षति, गंभीर अस्थि मज्जा दमन और इंजेक्शन से जुड़ी प्रतिक्रियाएँ हो सकती हैं। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल में एक स्वास्थ्य पेशेवर द्वारा दी जानी चाहिए। इलाज के दौरान नियमित रूप से रक्त की जांच, हृदय की कार्यप्रणाली और लीवर/किडनी की जांच करवानी चाहिए। संक्रमण से बचें और लाइव वैक्सीन न लगवाएं। गर्भनिरोधक उपाय अपनाएं।
💊 peg-adrim 50mg injection Uses & Benefits
[{"condition":"Ovarian cancer","description":"Used as part of combination chemotherapy for advanced ovarian cancer.","evidence":"Well-established"},{"condition":"AIDS-related Kaposi's sarcoma","description":"Indicated for the treatment of Kaposi's sarcoma in patients with AIDS.","evidence":"Well-established"},{"condition":"Multiple myeloma","description":"Used in combination with other agents for multiple myeloma.","evidence":"Well-established"},{"condition":"Breast cancer","description":"Sometimes used in the treatment of metastatic breast cancer.","evidence":"Established"}]
Off-label uses: [{"condition":"Non-Hodgkin lymphoma","description":"Occasionally used off-label as part of salvage regimens.","evidence":"Limited"},{"condition":"Soft tissue sarcoma","description":"May be used off-label in some sarcoma protocols.","evidence":"Limited"}]
Primary treatment for: Ovarian cancer
Also treats: AIDS-related Kaposi's sarcoma, Multiple myeloma, Breast cancer
📋 Drug Information
| Generic Name(s) | Doxorubicin (Liposomal) (50mg) |
| Brand Name | peg-adrim 50mg injection |
| Manufacturer | Fresenius Kabi India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Intravenous (IV) infusion |
| Storage | Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light. Keep in original packaging. |
| Shelf Life | Refer to the product label for the exact shelf life. Typically 18-24 months from the date of manufacture when stored properly. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine contains doxorubicin, which intercalates into DNA and inhibits topoisomerase II, leading to blockade of DNA replication and transcription. The liposomal formulation alters the distribution of the drug, increasing its concentration in tumor tissue and reducing exposure to normal tissues such as the heart.
Mechanism Steps
💡 How to Take peg-adrim 50mg injection
Strength: 50 mg liposomal doxorubicin injection
Dosage Information
| Adult Dosage | The dose of this medicine is determined by the oncologist based on the type of cancer, body surface area, and other treatments. It is usually given as an intravenous infusion over 30-60 minutes. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-administer. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Dose adjustments may be necessary based on kidney, liver, and heart function. Close monitoring is required. |
| Renal Impairment | Dose adjustment may be needed in patients with severe kidney impairment. Consult the prescribing oncologist. |
| Hepatic Impairment | Dose reduction is recommended in patients with liver impairment. Monitor liver function tests closely. |
| Maximum Daily Dose | The maximum cumulative dose is determined by the oncologist and depends on the patient's heart function and previous treatments. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of peg-adrim 50mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Live vaccines | Major | |
| Trastuzumab | Major | |
| Ketoconazole | Moderate | |
| Rifampin | Moderate | |
| Warfarin | Minor |
🚨 Major Interactions
- Live vaccines
- Cardiotoxic drugs (e.g., trastuzumab)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP3A4 inducers (e.g., rifampin)
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine, as it may worsen liver toxicity and increase nausea and vomiting.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to doxorubicin or any component of the formulation","Severe bone marrow suppression","Severe heart disease","Previous treatment with high cumulative doses of anthracyclines"]
⚠️ Warnings & Precautions
["This medicine can cause severe heart damage; regular monitoring is required.","It can suppress bone marrow, increasing risk of infection and bleeding.","Avoid contact with people who have infections.","Do not receive live vaccines during treatment.","Use effective contraception during and after treatment.","Report any signs of infection, bleeding, or heart problems immediately."]
🤱 Lactation Safety
It is not known if liposomal doxorubicin passes into breast milk. Because of the potential for serious adverse reactions in nursing infants, breastfeeding should be discontinued during treatment.
💊 Overdose Management
Overdose may cause severe bone marrow suppression and cardiotoxicity. Treatment is supportive and symptomatic. There is no specific antidote. Patients should be monitored closely in a hospital setting.
⏰ Missed Dose
This medicine is given by a healthcare professional in a clinic or hospital. If you miss an appointment, contact your doctor as soon as possible to reschedule. Do not attempt to self-administer.
Additional Safety Advice
This medicine must be given only by a healthcare professional in a controlled setting. Regular monitoring of blood counts, heart function, and liver/kidney tests is essential. Report any chest pain, shortness of breath, unusual bleeding, or signs of infection immediately. Avoid contact with people who have infections. Do not receive live vaccines while on this medicine. Use effective contraception during treatment and for several months after.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to side effects. Close monitoring of heart, kidney, and liver function is required. Dose adjustments may be necessary.
🤰 Pregnancy Planning (TTC)
This medicine can harm a fetus. Use effective contraception during treatment and for several months after. Discuss pregnancy planning with your doctor before starting treatment.
🏥 Post-Surgery Considerations
This medicine may affect wound healing and increase infection risk. Inform your surgeon that you are receiving this medicine before any surgery.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine. It may increase the risk of bleeding and infection. Your dentist may recommend postponing non-urgent procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Consult your doctor before starting any exercise program. Avoid strenuous activities if you have low blood counts or fatigue. Light walking and stretching may be beneficial.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause fatigue, nausea, and low blood counts, which can affect your ability to work or drive. Avoid driving if you feel dizzy or tired. Discuss work adjustments with your doctor.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your oncologist. Treatment duration is determined by your doctor based on your response and side effects.
📅 Long-Term Use Effects
Long-term use may increase the risk of heart damage, secondary cancers, and infertility. Regular monitoring of heart function, blood counts, and liver/kidney function is required. Discuss any concerns with your oncologist.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the cancer type, other chemotherapy drugs may be used.
Evidence: Well-establishedSome cancers may respond to targeted therapies.
Evidence: Established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Avoid live vaccines during treatment and for several months after. Inactivated vaccines may be given, but consult your doctor first.
📦 Storage Guide
✅ DO
Store refrigerated at 2°C to 8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original packaging
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not store at room temperature
✈️ Traveling with This Medicine
This medicine is administered in a hospital setting, so travel is not applicable. If you need to travel for treatment, carry your prescription and medical records. Store the medicine refrigerated at 2°C to 8°C during transport. Check with your doctor before planning any travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The anticancer effects begin within hours to days, but clinical response may take weeks. Your doctor will monitor your progress.
A: No, this medicine must be given by a healthcare professional in a clinic or hospital.
🤔 Common Patient Concerns
🔄 Substitutes for peg-adrim 50mg injection
View AllAlternative brands with exact same active ingredient:
-
oncodox 50mg injectionCipla Ltd ₹814.00 90.1% CHEAPER
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doxoson 50mg injectionResonance Laboratories Pvt Ltd ₹1,050.00 87.3% CHEAPER
-
doxopar 50mg injectionParenteral Drugs India Ltd ₹1,200.00 85.5% CHEAPER
-
pegadria 50mg injectionIntas Pharmaceuticals Ltd ₹7,827.52 5.2% CHEAPER
-
lipisol 50mg injectionAlkem Laboratories Ltd ₹8,163.26 1.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be self-administered at home.
Fact: No, it must be given by a healthcare professional in a clinic or hospital. - Myth: Liposomal doxorubicin has no side effects.
Fact: It can cause serious side effects, including heart damage and low blood counts.