paclo np 100mg/325mg tablet - Nimesulide (100mg) + Paracetamol (325mg) medicine

Paclo NP 100mg/325mg Tablet

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🏭 Colors Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

What is paclo np 100mg/325mg tablet used for?

Paclo NP 100mg/325mg Tablet is used for relief of pain and fever. It contains Nimesulide and Paracetamol, which work together to reduce inflammation and lower body temperature. It is commonly used for headaches, muscle aches, dental pain, and fever.

  • Generic Name: Nimesulide (100mg) + Paracetamol (325mg)
  • Manufacturer: Colors Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes
💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 paclo np 100mg/325mg tablet Uses & Benefits

  • Detailed medical information for paclo np 100mg/325mg tablet is being prepared by our medical team.
  • Please consult your doctor for complete information.

📋 Drug Information

Generic Name(s)Nimesulide (100mg) + Paracetamol (325mg)
Brand Namepaclo np 100mg/325mg tablet
ManufacturerColors Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageRoom temperature (15-30°C), away from moisture
Shelf LifeAs per manufacturer

💡 How to Take paclo np 100mg/325mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of paclo np 100mg/325mg tablet

✅ Common Side Effects

Nausea
Vomiting
Dizziness
Diarrhea
Skin rash

🚨 Serious Side Effects

Severe allergic reaction (rash, itching, swelling)
Liver damage (yellowing of skin/eyes, dark urine)
Stomach bleeding (black/tarry stools, vomit with blood)
Kidney problems (decreased urination, swelling)

⚠️ Rare Side Effects

Blood disorders (easy bruising/bleeding)
Stevens-Johnson syndrome (severe blistering skin rash)

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major Increased risk of bleeding
Methotrexate Major Increased methotrexate toxicity
Aspirin Moderate Increased risk of gastrointestinal bleeding

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • Aspirin
  • Ibuprofen
  • Diuretics

🍷 Alcohol Interaction

Avoid alcohol while taking Paclo NP Tablet as it increases the risk of liver damage and stomach bleeding. Alcohol can also worsen side effects like dizziness.

🛡️ Safety & Warnings

🚫 Contraindications

Do not use Paclo NP Tablet if you have severe liver disease, active stomach ulcer, bleeding disorders, or known allergy to Nimesulide or Paracetamol. Also avoid in patients with severe kidney impairment or during pregnancy (especially third trimester).

⚠️ Warnings & Precautions

Paclo NP Tablet should be used with caution in patients with liver or kidney disease, as it may worsen these conditions. Avoid prolonged use without medical supervision. If you experience symptoms of liver damage (yellowing of skin, dark urine) or allergic reactions, stop taking and seek medical help immediately. Do not take with other paracetamol-containing products to avoid overdose.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, abdominal pain, and liver damage. Treatment may involve activated charcoal and supportive care. Paracetamol overdose can be fatal if not treated promptly.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose to make up for a missed one.

🔄 Substitutes for paclo np 100mg/325mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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