Dapy-M 500 Tablet SR: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Severe nausea, vomiting, or abdominal pain
- Unusual tiredness or muscle pain
- Swelling of the face, lips, or throat
- Severe pain, redness, or swelling in the genital area
- Decreased urine output or blood in urine
- Yellowing of skin or eyes
If experiencing severe symptoms, call emergency services immediately.
What is oxramet xr 10mg/500mg tablet used for?
This medicine is a combination of dapagliflozin and metformin used to treat type 2 diabetes. It helps lower blood sugar by increasing glucose excretion in urine and reducing glucose production in the liver.
- Generic Name: Dapagliflozin (10mg) + Metformin (500mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 oxramet xr 10mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टाइप 2 डायबिटीज के इलाज के लिए इस्तेमाल की जाती है। यह शरीर में ब्लड शुगर को कंट्रोल करने में मदद करती है। इसमें डैपाग्लिफ्लोज़िन और मेटफॉर्मिन दो दवाएं होती हैं। डैपाग्लिफ्लोज़िन किडनी के जरिए शुगर को यूरिन से बाहर निकालती है और मेटफॉर्मिन लिवर में शुगर बनने को कम करती है। यह दवा उन लोगों के लिए है जिनका डायबिटीज दवा और एक्सरसाइज से कंट्रोल नहीं हो पाता। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के आम साइड इफेक्ट्स में जननांग में फंगल इन्फेक्शन, यूरिन इन्फेक्शन, जी मिचलाना, दस्त, पेट दर्द और सिरदर्द शामिल हैं। गंभीर साइड इफेक्ट्स में डायबिटिक कीटोएसिडोसिस, लैक्टिक एसिडोसिस और किडनी की समस्या हो सकती है। अगर आपको सांस लेने में तकलीफ, पेट में तेज दर्द, उल्टी, या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से डोज न बदलें। खूब पानी पिएं ताकि यूरिन इन्फेक्शन का खतरा कम हो। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अगर आपको किडनी या लिवर की बीमारी है तो डॉक्टर को बताएं। प्रेग्नेंसी या ब्रेस्टफीडिंग के दौरान डॉक्टर की सलाह के बिना न लें।
💊 oxramet xr 10mg/500mg tablet Uses & Benefits
[{"condition":"Type 2 Diabetes Mellitus","description":"Improves glycemic control in adults when metformin alone or dapagliflozin alone does not achieve target HbA1c levels.","evidence":"Well-established"},{"condition":"Type 2 Diabetes with Cardiovascular Risk","description":"May reduce the risk of cardiovascular events in patients with type 2 diabetes and established cardiovascular disease.","evidence":"Well-established"},{"condition":"Type 2 Diabetes with Chronic Kidney Disease","description":"May slow the progression of kidney disease in patients with type 2 diabetes and diabetic nephropathy.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Weight Management in Type 2 Diabetes","description":"Dapagliflozin component may promote modest weight loss, but this is not a primary indication.","evidence":"Limited"},{"condition":"Non-Alcoholic Fatty Liver Disease","description":"Some studies suggest potential benefit, but this is not an approved indication.","evidence":"Limited"}]
Primary treatment for: Type 2 Diabetes Mellitus
Also treats: Cardiovascular disease, Chronic kidney disease, Obesity
📋 Drug Information
| Generic Name(s) | Dapagliflozin (10mg) + Metformin (500mg) |
| Brand Name | oxramet xr 10mg/500mg tablet |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Dapagliflozin inhibits sodium-glucose co-transporter 2 (SGLT2) in the proximal tubules of the kidneys, reducing glucose reabsorption and increasing urinary glucose excretion. Metformin decreases hepatic glucose production, reduces intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization. Together, they lower blood glucose levels through independent pathways.
Mechanism Steps
💡 How to Take oxramet xr 10mg/500mg tablet
Strength: Tablet containing Dapagliflozin 10 mg and Metformin 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once daily with meals. The dose may be adjusted by your doctor based on your blood sugar levels, kidney function, and overall health. Do not change the dose without consulting your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be needed based on renal function. Consult your doctor. |
| Renal Impairment | Dapagliflozin: No dose adjustment for mild to moderate renal impairment. Not recommended if eGFR < 45 mL/min/1.73 m² for glycemic control. Metformin: Contraindicated if eGFR < 30 mL/min/1.73 m². Dose adjustment may be needed for eGFR 30-45 mL/min/1.73 m². Consult your doctor. |
| Hepatic Impairment | Dapagliflozin: No dose adjustment for mild to moderate hepatic impairment. Not recommended for severe hepatic impairment. Metformin: Use with caution in hepatic impairment due to risk of lactic acidosis. Consult your doctor. |
| Maximum Daily Dose | Dapagliflozin 10 mg and Metformin 500 mg once daily. The maximum recommended dose of metformin is 2000 mg per day, but this combination is fixed at 500 mg per tablet. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of oxramet xr 10mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Contrast media | Major | |
| Alcohol | Major | |
| Diuretics | Moderate | |
| Insulin | Moderate | |
| Sulfonylureas | Moderate | |
| Cationic drugs | Moderate | |
| NSAIDs | Minor |
🚨 Major Interactions
- Contrast media (iodinated)
- Alcohol
⚡ Moderate Interactions
- Diuretics
- Insulin or sulfonylureas
- Cationic drugs (e.g., amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamterene, trimethoprim, vancomycin)
🍷 Alcohol Interaction
Avoid excessive alcohol consumption while taking this medicine because it increases the risk of lactic acidosis and hypoglycemia. If you drink alcohol, do so in moderation and only after consulting your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe renal impairment (eGFR < 30 mL/min/1.73 m²)","Acute or chronic metabolic acidosis, including diabetic ketoacidosis","Hypersensitivity to dapagliflozin, metformin, or any component of the formulation","Type 1 diabetes mellitus","Severe hepatic impairment"]
⚠️ Warnings & Precautions
["Lactic acidosis: Rare but serious; seek immediate medical help if symptoms occur.","Diabetic ketoacidosis: May occur even with normal blood sugar levels.","Urinary tract infections: Monitor and treat promptly.","Genital fungal infections: Maintain hygiene and treat as needed.","Hypotension: May occur due to diuresis; monitor blood pressure.","Vitamin B12 deficiency: Long-term metformin use may reduce B12 levels.","Surgery: Discontinue before surgery and restart after renal function is normal.","Alcohol: Avoid excessive consumption."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Symptoms may include severe hypoglycemia, lactic acidosis, or dehydration. Treatment is supportive and symptomatic. Hemodialysis may be considered for metformin overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Stay well hydrated to help your kidneys flush out glucose and reduce the risk of urinary infections. Maintain good genital hygiene to prevent fungal infections. Avoid excessive alcohol consumption because it increases the risk of lactic acidosis. Inform your doctor if you have kidney or liver problems, or if you are scheduled for surgery or imaging tests with contrast dyes. Check your blood sugar regularly as advised. Do not use this medicine if you are pregnant, planning pregnancy, or breastfeeding without consulting your doctor. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially regarding kidney function. Regular monitoring of renal function is recommended. Dose adjustment may be needed based on kidney function.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy. If you are planning to become pregnant, consult your doctor to discuss alternative treatments for diabetes. Good blood sugar control before and during pregnancy is important for both mother and baby.
🏥 Post-Surgery Considerations
Discontinue this medicine before surgery and restart only after your doctor confirms that your kidney function is normal. This is important to reduce the risk of lactic acidosis.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. No specific precautions are usually needed, but maintaining good oral hygiene is important for people with diabetes.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise is beneficial for managing diabetes, but you should monitor your blood sugar levels before and after exercise. If you experience symptoms of low blood sugar, such as dizziness or sweating, stop exercising and consume a fast-acting carbohydrate. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Otherwise, it should not significantly impact your daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your blood sugar levels are well-controlled, your doctor may adjust or stop the medicine. Always follow your doctor's advice.
📅 Long-Term Use Effects
Long-term use of this medicine may require regular monitoring of kidney function, blood sugar levels, and vitamin B12 levels. Metformin can cause vitamin B12 deficiency over time. Dapagliflozin may increase the risk of urinary tract infections. Regular follow-up with your doctor is essential to monitor for any complications and adjust the dose as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Lifestyle modifications are essential for managing type 2 diabetes and can complement medicine.
Evidence: Well-establishedDepending on your condition, your doctor may prescribe other medicines like sulfonylureas, DPP-4 inhibitors, or insulin.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, patients with diabetes are advised to receive routine vaccinations, including influenza and pneumococcal vaccines, as recommended by their doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If traveling across time zones, consult your doctor about adjusting the timing of your dose. Keep enough supply for your entire trip and carry it in your hand luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few hours, but it may take several weeks to see the full effect on your blood sugar levels.
A: Yes, but only under your doctor's supervision. Your dose may need adjustment to avoid low blood sugar.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for oxramet xr 10mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
-
dgson m 10mg/500mg tabletUnison Healthcare ₹60.75 52.5% CHEAPER
-
novidap-m tablet erMetamorf Lifesciences ₹88.13 31.1% CHEAPER
-
dapend-10 m tablet erHalberd Pharmaceuticals ₹102.19 20.2% CHEAPER
-
dapashot-m 10/500 tablet erCapitis Healthcare Pvt Ltd ₹102.68 19.8% CHEAPER
-
dapajust m 10mg/500mg tabletErinyle Pharma ₹103.13 19.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure diabetes.
Fact: This medicine helps manage blood sugar levels but does not cure diabetes. - Myth: This medicine can be taken without diet and exercise.
Fact: A healthy diet and regular exercise are essential for managing diabetes. - Myth: This medicine causes weight gain.
Fact: Dapagliflozin may cause modest weight loss, while metformin is weight-neutral.
🔄 Alternative Options
Generic Alternatives
- Dapagliflozin and Metformin combination tablets
Brand Alternatives
- Dapy-M 500 Tablet SR