orolam-p tablet - Alprazolam (0.25mg) + Propranolol (20mg) medicine

Beta Anxit 0.25 mg/20 mg Tablet: Complete Information

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🏭 Rishab Healthcare pvt. Ltd. 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Both alprazolam and propranolol may pose risks to the fetus. Use only if clearly needed and under medical supervision. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Limited for the combination; individual components have well-established evidence for their respective uses.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe drowsiness or difficulty staying awake
  • Slow or irregular heartbeat
  • Difficulty breathing or shortness of breath
  • Severe dizziness or fainting
  • Confusion or hallucinations
  • Yellowing of skin or eyes
  • Unusual bleeding or bruising
  • Severe allergic reaction (rash, swelling, difficulty breathing)

If experiencing severe symptoms, call emergency services immediately.

What is orolam-p tablet used for?

This medicine is a combination of Alprazolam (0.25 mg) and Propranolol (20 mg) used for short-term treatment of anxiety disorders. Alprazolam is a benzodiazepine that calms the brain, while Propranolol is a beta-blocker that reduces physical anxiety symptoms like rapid heartbeat and tremors. It is taken orally, usually once or twice daily, and should not be stopped suddenly.

  • Generic Name: Alprazolam (0.25mg) + Propranolol (20mg)
  • Manufacturer: Rishab Healthcare pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 orolam-p tablet के बारे में (Hindi Summary)

उपयोग: यह दवा अल्प्राजोलम 0.25 मिलीग्राम और प्रोप्रानोलोल 20 मिलीग्राम का संयोजन है। इसका उपयोग चिंता विकारों के अल्पकालिक उपचार के लिए किया जाता है। अल्प्राजोलम एक बेंजोडायजेपाइन है जो मस्तिष्क को शांत करता है, जबकि प्रोप्रानोलोल एक बीटा-ब्लॉकर है जो दिल की धड़कन तेज होना, कंपन और पसीना जैसे शारीरिक लक्षणों को कम करता है। यह दवा मुंह से ली जाती है और डॉक्टर के निर्देशानुसार ही लेनी चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, थकान, हाथ-पैर ठंडे होना, नींद में गड़बड़ी और याददाश्त में कमी शामिल हैं। गंभीर दुष्प्रभावों में तेज धड़कन धीमी होना, सांस लेने में कठिनाई, भ्रम और अवसाद शामिल हो सकते हैं। यदि कोई दुष्प्रभाव लंबे समय तक बना रहे तो डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा न बढ़ाएं या घटाएं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन न चलाएं या मशीनरी न चलाएं। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। इस दवा को अचानक बंद न करें, इससे गंभीर लक्षण हो सकते हैं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 orolam-p tablet Uses & Benefits

[{"condition":"Anxiety disorders","description":"Used for short-term relief of anxiety symptoms, especially when both psychological and physical symptoms are present.","evidence":"Well-established for short-term use"},{"condition":"Panic disorder","description":"May be used to reduce the frequency and severity of panic attacks.","evidence":"Limited evidence for combination; individual components have evidence"},{"condition":"Performance anxiety","description":"Sometimes prescribed for situational anxiety such as public speaking or exams.","evidence":"Limited, off-label"}]

Off-label uses: [{"condition":"Irritable bowel syndrome (IBS) with anxiety","description":"May help reduce anxiety-related gastrointestinal symptoms.","evidence":"Limited"},{"condition":"Tremor","description":"Propranolol component may help reduce tremors.","evidence":"Limited"}]

Primary treatment for: Anxiety disorders

Also treats: Panic disorder, Performance anxiety, Irritable bowel syndrome with anxiety

📋 Drug Information

Generic Name(s)Alprazolam (0.25mg) + Propranolol (20mg)
Brand Nameorolam-p tablet
ManufacturerRishab Healthcare pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed; do not adjust the dose without consulting your doctor.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not stop this medicine abruptly; your doctor will gradually reduce the dose to prevent withdrawal symptoms.
4
Avoid alcohol and other CNS depressants while taking this medicine.
5
Inform your doctor if you have a history of asthma, heart problems, or substance abuse.
6
Keep all follow-up appointments to monitor your response and adjust the dose if needed.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Anxiety
This medicine is commonly prescribed for anxiety disorders.
Likely Use
Rapid heartbeat
Propranolol component helps reduce heart rate.
Likely Use
Tremors
Propranolol helps reduce tremors.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAlprazolam is rapidly absorbed from the gastrointestinal tract, with peak plasma concentrations reached in 1-2 hours. Propranolol is also rapidly and almost completely absorbed, with peak levels in 1-2 hours. Food may slightly delay absorption but does not significantly affect the extent.
DistributionAlprazolam is highly lipophilic and distributes widely into body tissues, including the brain. Propranolol is also highly lipophilic and crosses the blood-brain barrier. Both drugs have large volumes of distribution.
Protein BindingAlprazolam is approximately 80% bound to plasma proteins. Propranolol is approximately 90% bound to plasma proteins, primarily albumin.
MetabolismAlprazolam is metabolized in the liver primarily by CYP3A4 to active metabolites. Propranolol undergoes extensive first-pass metabolism in the liver, mainly by CYP2D6 and CYP1A2, to active metabolites.
Half-LifeAlprazolam: 6-12 hours; Propranolol: 3-6 hours.
ExcretionAlprazolam metabolites are excreted primarily in urine. Propranolol metabolites are excreted in urine and bile.
BioavailabilityAlprazolam: approximately 90%; Propranolol: approximately 30% due to first-pass metabolism.
Onset of ActionAlprazolam: 30-60 minutes; Propranolol: 30-60 minutes.
Peak Plasma TimeAlprazolam: 1-2 hours; Propranolol: 1-2 hours.
Duration of ActionAlprazolam: 6-12 hours; Propranolol: 6-12 hours.

How It Works

Alprazolam binds to the benzodiazepine site on the GABA-A receptor, enhancing the inhibitory effect of GABA, which leads to sedation, anxiolysis, and muscle relaxation. Propranolol blocks beta-adrenergic receptors, reducing the physical symptoms of anxiety such as tachycardia, tremor, and sweating. The combination targets both the central and peripheral manifestations of anxiety.

Mechanism Steps

1
GABA-A receptor modulation: Alprazolam binds to the benzodiazepine site on the GABA-A receptor, increasing the frequency of chloride channel opening and enhancing GABA-mediated inhibition in the brain.
2
Beta-adrenergic blockade: Propranolol competitively blocks beta-adrenergic receptors, reducing the effects of adrenaline and noradrenaline on the heart and blood vessels.
3
Reduction of physical anxiety symptoms: By blocking beta receptors, propranolol decreases heart rate, tremor, and sweating, which are common physical symptoms of anxiety.
4
Combined anxiolytic effect: The combination provides rapid relief of both the emotional and physical symptoms of anxiety.

💡 How to Take orolam-p tablet

Strength: Tablet containing Alprazolam 0.25 mg and Propranolol 20 mg.

1Take this medicine orally with a glass of water.
2Take it at the same time each day as prescribed.
3You may take it with or without food, but taking it with food may reduce stomach upset.
4Swallow the tablet whole; do not crush or chew.
5Do not take more than the prescribed dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally one to two times daily, or as directed by your doctor. The dose may be adjusted based on your response and tolerance. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Monitor for drowsiness, confusion, and falls.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum daily dose should not exceed the prescribed amount. Typically, alprazolam should not exceed 4 mg/day and propranolol should not exceed 640 mg/day, but the combination's maximum dose must be determined by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and may minimize drowsiness.
Grapefruit
Avoid
May increase alprazolam levels.
Alcohol
Avoid
Increases sedation and risk of respiratory depression.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of orolam-p tablet

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. Usually diminishes with continued use.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Stay hydrated.
Fatigue (Common (5-10%))
Get adequate rest. Consult doctor if persistent.
Cold extremities (Common (5-10%))
Warm clothing may help. Report if severe or painful.
Sleep disturbances (Common (5-10%))
Maintain good sleep hygiene. Consult doctor if insomnia persists.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling, severe dizziness, or difficulty breathing.
Slow heart rate (bradycardia) (Uncommon (0.1-1%))
Contact doctor if you feel faint, very slow pulse, or unusual weakness.
Mental confusion (Uncommon (0.1-1%))
Report to doctor immediately. Avoid driving.
Depression (Uncommon (0.1-1%))
Consult doctor if you feel persistently sad or hopeless.

⚠️ Rare Side Effects

Hallucinations
Seek immediate medical attention.
Jaundice
Report yellowing of skin or eyes to doctor immediately.
Blood disorders (e.g., thrombocytopenia)
Report unusual bleeding or bruising to doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Fluoxetine Major
Verapamil Major
Clonidine Major
Alcohol Major
Opioids Moderate
NSAIDs Moderate
Antidiabetics Moderate
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
  • Calcium channel blockers (e.g., verapamil, diltiazem)
  • Clonidine

⚡ Moderate Interactions

  • CNS depressants (e.g., alcohol, opioids, antihistamines)
  • NSAIDs
  • Antidiabetics

🍷 Alcohol Interaction

Alcohol increases the sedative effects of alprazolam and can dangerously lower blood pressure and heart rate with propranolol. Avoid alcohol completely while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to alprazolam, propranolol, or any component of the formulation","Severe respiratory depression or acute narrow-angle glaucoma","Asthma or severe chronic obstructive pulmonary disease","Severe bradycardia, heart block greater than first degree, cardiogenic shock","Decompensated heart failure","Myasthenia gravis","Severe hepatic impairment","Pregnancy and breastfeeding"]

⚠️ Warnings & Precautions

["This medicine may cause drowsiness and impair ability to drive or operate machinery.","Do not stop this medicine abruptly; withdrawal symptoms may occur.","Use with caution in elderly patients due to increased risk of falls and confusion.","May cause dependence and withdrawal symptoms with prolonged use.","Avoid alcohol and other CNS depressants.","Inform your doctor if you have a history of substance abuse.","Use with caution in patients with diabetes as propranolol may mask hypoglycemia symptoms.","May worsen symptoms of Raynaud's phenomenon or peripheral vascular disease."]

🤱 Lactation Safety

Alprazolam and propranolol are excreted in breast milk. Breastfeeding is not recommended while taking this medicine due to potential risk to the infant. Consult your doctor for alternatives.

💊 Overdose Management

Overdose can cause severe drowsiness, confusion, slow heart rate, low blood pressure, difficulty breathing, and coma. Seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if within 1-2 hours of ingestion. Flumazenil may be used for benzodiazepine overdose but is contraindicated in mixed overdose with tricyclic antidepressants. Glucagon and vasopressors may be used for propranolol toxicity.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without consulting your doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol while taking this medicine as it can increase drowsiness and dizziness. Do not stop this medicine abruptly as it can cause withdrawal symptoms such as anxiety, insomnia, and tremors. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the effects of this medicine. Start with a lower dose and monitor for drowsiness, confusion, and falls. Avoid if possible due to increased risk of cognitive impairment.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for alternative treatments. Both alprazolam and propranolol may harm the fetus.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure. It may need to be stopped before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may interact with local anesthetics containing epinephrine, and you may be more prone to drowsiness. Avoid driving to and from dental appointments.

💚 Lifestyle Tips for Better Results

🏃
Practice relaxation techniques such as deep breathing and meditation.
🥗
Maintain a regular sleep schedule.
😴
Engage in regular physical activity, but avoid strenuous exercise if you feel dizzy.
💧
Limit caffeine intake as it can worsen anxiety.
🧘
Join a support group or seek counseling for anxiety management.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Dizziness and drowsiness may increase the risk of injury.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Avoid caffeine and alcohol.
Stay hydrated.
Include foods rich in omega-3 fatty acids.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, which may affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how it affects you. Inform your employer if your job requires alertness.

🛑 When to Stop This Medicine

Do not stop this medicine abruptly. Your doctor will gradually reduce the dose to prevent withdrawal symptoms. Consult your doctor if you experience side effects or if you wish to discontinue.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to tolerance, dependence, and withdrawal symptoms. It may also cause cognitive impairment and memory problems. Regular monitoring by a doctor is essential. It is generally recommended for short-term use only.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cognitive behavioral therapy (CBT)

First-line treatment for anxiety disorders; helps change thought patterns.

Evidence: Well-established
Selective serotonin reuptake inhibitors (SSRIs)

Long-term treatment for anxiety; takes weeks to work but no dependence.

Evidence: Well-established
Mindfulness and relaxation techniques

Can help reduce anxiety symptoms.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Check local customs regulations regarding controlled substances.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with generalized anxiety disorder
She was prescribed this medicine for short-term relief of anxiety while starting therapy. She noticed significant reduction in her physical symptoms like racing heart and trembling within a week. She was advised not to stop suddenly and to attend regular follow-ups. She gradually tapered off after 3 months under medical supervision.
💡 Lesson: This medicine can provide rapid relief of anxiety symptoms but should be used short-term and tapered gradually.
👤 A 50-year-old man with performance anxiety
He was prescribed this medicine to take before public speaking engagements. He found it helpful in reducing his tremors and rapid heartbeat. However, he experienced drowsiness initially, so he was advised to take it at bedtime and adjust timing. He was cautioned not to drive after taking it.
💡 Lesson: Timing of dose is important to minimize side effects; avoid driving until you know how it affects you.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30-60 minutes after taking a dose.

Q: Can I take this medicine with other medications?

A: Inform your doctor about all medications you are taking, as this medicine can interact with many drugs.

Q: Is it safe to take during pregnancy?

A: This medicine is not recommended during pregnancy. Consult your doctor for safer alternatives.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for orolam-p tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a cure for anxiety.
    Fact: This medicine provides symptomatic relief but is not a cure. It is usually used short-term along with therapy.
  • Myth: I can stop this medicine whenever I want.
    Fact: Abrupt discontinuation can cause withdrawal symptoms. Always taper under medical supervision.
  • Myth: It is safe to take extra doses if I feel more anxious.
    Fact: Taking more than prescribed can lead to severe side effects and dependence. Follow your doctor's instructions exactly.

🔄 Alternative Options

Generic Alternatives

  • Alprazolam 0.25 mg + Propranolol 20 mg tablet (generic)

Brand Alternatives

  • Beta Anxit 0.25 mg/20 mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Alprazolam alone","difference":"Only benzodiazepine; does not target physical symptoms like propranolol."},{"medicine":"Propranolol alone","difference":"Only beta-blocker; does not provide central anxiolysis."},{"medicine":"SSRIs (e.g., sertraline)","difference":"First-line for long-term anxiety but take weeks to work; no immediate physical symptom relief."}]

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