cool burn cream - Chlorhexidine Gluconate (0.2% w/w) + Silver Sulfadiazine (1% w/w) medicine

cool burn cream

4.7 (9 reviews)
๐Ÿญ Rishab Healthcare pvt. Ltd. ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is cool burn cream used for?

Burnhit Cream (Chlorhexidine Gluconate + Silver Sulfadiazine) is used to treat DERMA. It contains Chlorhexidine Gluconate (0.2% w/w) + Silver Sulfadiazine (1% w/w), which Chlorhexidine disrupts microbial cell membranes; silver sulfadiazine releases si. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Chlorhexidine Gluconate + Silver Sulfadiazine
  • Manufacturer: Rishab Healthcare pvt. Ltd.
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š cool burn cream Uses & Benefits

Prevention and treatment of wound infection in second- and third-degree burns.

Off-label uses: Diabetic foot ulcers, Pressure ulcers, Venous stasis ulcers

๐Ÿ“‹ Drug Information

Generic Name(s)Chlorhexidine Gluconate + Silver Sulfadiazine
Brand NameBurnhit Cream
ManufacturerRishab Healthcare pvt. Ltd.
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassAntiseptic and Antimicrobial
Route of AdministrationTopical
StorageStore at room temperature (20-25ยฐC); protect from heat and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionMinimal systemic absorption through intact skin; absorption may increase through burned or damaged skin.
DistributionPrimarily local at site of application; limited systemic distribution.
Protein BindingNot well characterized; silver sulfadiazine is highly protein bound (>90%)
MetabolismChlorhexidine is minimally metabolized; silver sulfadiazine is metabolized in the liver.
Half-LifeNot well defined for topical application; systemic half-life of silver sulfadiazine is approximately
ExcretionChlorhexidine is excreted primarily in feces; silver sulfadiazine and its metabolites are excreted in urine.
BioavailabilityLow systemic bioavailability due to topical application.
Onset of ActionRapid; within hours.
Peak Plasma TimeNot applicable for topical use.
Duration of ActionUp to 24 hours with proper application.

How It Works

Chlorhexidine disrupts microbial cell membranes; silver sulfadiazine releases silver ions that bind to microbial DNA and inhibit cell division.

Mechanism Steps

1Chlorhexidine binds to microbial cell membrane phospholipids, increasing permeability and causing leakage of cytoplasmic contents.
2Silver sulfadiazine dissociates to release silver ions, which bind to microbial DNA and inhibit replication.
3Silver ions also bind to sulfhydryl groups in bacterial enzymes, disrupting metabolism.

๐Ÿ’ก How to Take cool burn cream

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cool burn cream

โœ… Common Side Effects

  • Skin irritation
  • Burning sensation
  • Itching
  • Rash

๐Ÿšจ Serious Side Effects

  • Allergic reactions
  • Stevens-Johnson syndrome
  • Leukopenia
  • Renal toxicity

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Methemoglobinemia
  • Photosensitivity

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Phenytoin Major Increased phenytoin levels
Oral hypoglycemics Major Increased hypoglycemic effect
Cimetidine Moderate Increased silver sulfadiazine levels
Probenecid Moderate Decreased renal excretion of silver
Loop diuretics Moderate Increased nephrotoxicity risk
Antacids Minor Decreased absorption of chlorhexidine
Iron supplements Minor Decreased iron absorption

๐Ÿšจ Major Interactions

  • Warfarin
  • Phenytoin
  • Oral hypoglycemics

โšก Moderate Interactions

  • Cimetidine
  • Probenecid
  • Loop diuretics

โ„น๏ธ Minor Interactions

  • Antacids
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to chlorhexidine, silver sulfadiazine, or sulfonamides; pregnancy near term; premature infants.

๐Ÿ“Š Monitoring Parameters

Monitor for signs of infection, allergic reactions, and renal function in extensive burns.

๐Ÿคฑ Lactation Safety

Use with caution; limited data.

๐Ÿ’Š Overdose Management

Overdose unlikely; if systemic toxicity occurs, discontinue use and provide supportive care.

โฐ Missed Dose

Apply as soon as remembered; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

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