Alsara N 100mg/10mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
If experiencing severe symptoms, call emergency services immediately.
What is opel serra 100 mg/10 mg tablet used for?
This medicine is a combination of nimesulide and serratiopeptidase used for short-term relief of pain and inflammation in conditions like arthritis and injuries. It works by reducing pain and swelling. Take it with food and avoid alcohol.
- Generic Name: Nimesulide (100mg) + Serratiopeptidase (10mg)
- Manufacturer: Stanford Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 opel serra 100 mg/10 mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नाइमेसुलाइड और सेरेशियोपेप्टिडेज़ का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह गठिया, चोट, और सर्जरी के बाद होने वाली सूजन और दर्द में राहत देती है। इसे भोजन के साथ लें और शराब से बचें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, दस्त, और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, लीवर और किडनी की समस्या हो सकती है। यदि काला मल, उल्टी में खून, या पेट में तेज दर्द हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें। शराब न पिएं। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। गर्भवती महिलाएं और स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।
💊 opel serra 100 mg/10 mg tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and improves joint mobility in knee, hip, and hand osteoarthritis.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness as part of a comprehensive treatment plan.","evidence":"Well-established"},{"condition":"Post-operative inflammation","description":"Helps reduce swelling and pain after surgery or dental procedures.","evidence":"Moderate"},{"condition":"Acute musculoskeletal injuries","description":"Provides short-term relief for sprains, strains, and sports injuries.","evidence":"Moderate"},{"condition":"Ankylosing spondylitis","description":"May help relieve pain and stiffness in the spine and sacroiliac joints.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label for preventing migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, but not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation associated with musculoskeletal and joint disorders
Also treats: Osteoarthritis, Rheumatoid arthritis, Post-operative inflammation, Acute musculoskeletal injuries
📋 Drug Information
| Generic Name(s) | Nimesulide (100mg) + Serratiopeptidase (10mg) |
| Brand Name | opel serra 100 mg/10 mg tablet |
| Manufacturer | Stanford Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Nimesulide selectively inhibits the cyclooxygenase-2 (COX-2) enzyme, which reduces the production of prostaglandins that cause pain and inflammation. Serratiopeptidase is a proteolytic enzyme that breaks down fibrin and other proteins involved in swelling and tissue repair, thereby reducing edema and promoting healing.
Mechanism Steps
💡 How to Take opel serra 100 mg/10 mg tablet
Strength: Each tablet contains nimesulide 100 mg and serratiopeptidase 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet two to three times daily, taken with food. The exact dose and duration depend on the condition being treated, your age, weight, kidney and liver function, and response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Avoid in patients with severe liver disease. Use with caution in mild to moderate liver impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of nimesulide is 200 mg. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of opel serra 100 mg/10 mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| ACE inhibitors | Major | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| Methotrexate | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs
- ACE inhibitors
⚡ Moderate Interactions
- Diuretics
- Lithium
- Methotrexate
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding and liver damage.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or history of recurrent ulcers","Severe kidney disease","Severe liver disease","Known allergy to nimesulide or serratiopeptidase","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Third trimester of pregnancy","Children under 12 years","Bleeding disorders"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol.","Do not use for more than 7-10 days without medical advice.","Use with caution in the elderly.","Monitor for signs of bleeding.","Inform your doctor if you have heart, kidney, or liver disease.","Do not drive if you feel dizzy."]
🤱 Lactation Safety
Not established from the available information. It is not known if nimesulide or serratiopeptidase pass into breast milk. Consult your doctor before use.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, drowsiness, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, high blood pressure, or heart problems. Do not take other painkillers or NSAIDs without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester. If you are planning pregnancy, consult your doctor to discuss safer alternatives.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to reduce pain and swelling. Take it as directed by your surgeon. Inform your surgeon if you have any bleeding disorders or are on blood thinners.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you have joint pain or swelling. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest if you feel unwell.
🛑 When to Stop This Medicine
Stop taking this medicine if you experience severe side effects such as stomach bleeding, allergic reactions, or yellowing of eyes. Do not stop abruptly if you are on a prescribed course; consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney problems, liver damage, and cardiovascular events. It is not recommended for extended use. Regular monitoring of kidney and liver function may be needed if prolonged use is necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedHelps reduce swelling and pain in injuries.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known interactions with vaccines, but consult your doctor if you are scheduled for vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the tablet.
A: It is best taken with food to reduce the risk of stomach upset.
A: Do not take other NSAIDs without consulting your doctor, as it increases the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for opel serra 100 mg/10 mg tablet
View AllAlternative brands with exact same active ingredient:
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nelsid s 100mg/10mg tabletInd Swift Laboratories Ltd ₹11.60 56.7% CHEAPER
-
alsera n 100 mg/10 mg tabletAlkem Laboratories Ltd ₹12.37 53.8% CHEAPER
-
oxin plus syrupSynokem Pharmaceuticals Ltd ₹17.51 34.6% CHEAPER
-
Serrocon N 100 mg/10 mg TabletIcon Pharma & Surgicals Pvt Ltd ₹29.77 11.2% COSTLIER
-
bay serra 100mg/10mg tabletDivine Lifecare Pvt Ltd ₹33.28 24.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: It is meant for short-term use only. Long-term use increases the risk of stomach, kidney, and liver problems. - Myth: It is safe to take without food.
Fact: Taking it without food increases the risk of stomach upset and ulcers. Always take it with food.
🔄 Alternative Options
Generic Alternatives
- Nimesulide + Serratiopeptidase generic tablets
Brand Alternatives
- Alsera N 100 mg/10 mg Tablet