ondai 8mg tablet - Ondansetron (8mg) medicine

Emeset 8 Tablet: Complete Medicine Guide

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🏭 Medley Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: High
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reactions such as rash, itching, swelling of face, lips, or throat, or difficulty breathing.
  • Irregular heartbeat, palpitations, or fainting.
  • Symptoms of serotonin syndrome such as agitation, hallucinations, fever, rapid heart rate, or muscle stiffness.
  • Severe headache with visual changes.
  • Yellowing of skin or eyes.
  • Decreased urine output.

If experiencing severe symptoms, call emergency services immediately.

What is ondai 8mg tablet used for?

This medicine is an antiemetic used to prevent and treat nausea and vomiting caused by chemotherapy, radiation, or surgery. It works by blocking serotonin receptors in the brain and gut.

  • Generic Name: Ondansetron (8mg)
  • Manufacturer: Medley Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ondai 8mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ओंडान्सेट्रॉन 8 मिलीग्राम की गोली है, जिसका उपयोग मतली और उल्टी को रोकने और इलाज करने के लिए किया जाता है। यह कीमोथेरेपी, रेडिएशन थेरेपी और सर्जरी के कारण होने वाली मतली और उल्टी के लिए आमतौर पर दी जाती है। यह दवा सेरोटोनिन नामक पदार्थ को ब्लॉक करके काम करती है, जो उल्टी की प्रतिक्रिया को ट्रिगर कर सकता है। यह दवा केवल डॉक्टर के पर्चे पर ही ली जानी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, कब्ज, थकान, चक्कर आना और नींद आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, अनियमित दिल की धड़कन और सेरोटोनिन सिंड्रोम हो सकते हैं। अगर आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। एक बार में एक गोली पानी के साथ निगलें। इसे खाने के साथ या बिना खाने के लिया जा सकता है। इस दवा को लेते समय शराब न पिएं क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक गाड़ी न चलाएं। अगर आप गर्भवती हैं, गर्भवती होने की योजना बना रही हैं, या स्तनपान करा रही हैं, तो अपने डॉक्टर को बताएं। इस दवा को बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 ondai 8mg tablet Uses & Benefits

[{"condition":"Chemotherapy-induced nausea and vomiting","description":"Prevents and treats nausea and vomiting caused by cancer chemotherapy.","evidence":"Well-established"},{"condition":"Radiation-induced nausea and vomiting","description":"Helps control nausea and vomiting resulting from radiation therapy.","evidence":"Well-established"},{"condition":"Postoperative nausea and vomiting","description":"Used to prevent and treat nausea and vomiting after surgery.","evidence":"Well-established"},{"condition":"Nausea and vomiting from other causes","description":"May be used for nausea and vomiting due to other medical conditions or medications.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Hyperemesis gravidarum","description":"Sometimes used off-label to treat severe nausea and vomiting during pregnancy.","evidence":"Limited"},{"condition":"Cyclic vomiting syndrome","description":"May be prescribed off-label to manage cyclic vomiting syndrome.","evidence":"Limited"}]

Primary treatment for: Nausea and vomiting

Also treats: Chemotherapy-induced nausea and vomiting, Postoperative nausea and vomiting, Radiation-induced nausea and vomiting

📋 Drug Information

Generic Name(s)Ondansetron (8mg)
Brand Nameondai 8mg tablet
ManufacturerMedley Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin antagonists (5-HT3 antagonists)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed by your doctor.
2
Swallow the tablet whole with a glass of water.
3
You can take it with or without food.
4
Avoid alcohol while taking this medicine as it may increase drowsiness.
5
Do not drive or operate heavy machinery until you know how this medicine affects you.
6
Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
7
Keep this medicine out of reach of children.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Nausea and vomiting
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed after oral administration. The absolute bioavailability is approximately 60% due to first-pass metabolism.
DistributionThis medicine is distributed widely in the body. It crosses the blood-brain barrier and placenta. Protein binding is about 70-76%.
Protein BindingApproximately 70-76% bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver by multiple cytochrome P450 enzymes, including CYP3A4, CYP2D6, and CYP1A2.
Half-LifeThe elimination half-life is approximately 3 to 6 hours in healthy adults.
ExcretionThis medicine is excreted primarily in the urine and feces as metabolites. Less than 5% is excreted unchanged in urine.
BioavailabilityThe oral bioavailability is approximately 60%.
Onset of ActionThe onset of action is within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentration is reached approximately 1.5 to 2 hours after oral administration.
Duration of ActionThe duration of action is approximately 4 to 8 hours.

How It Works

This medicine works by selectively blocking serotonin 5-HT3 receptors in the central nervous system and gastrointestinal tract. Serotonin is a chemical that can trigger the vomiting reflex. By blocking these receptors, this medicine prevents nausea and vomiting.

Mechanism Steps

1
Binding to 5-HT3 receptors: This medicine binds to serotonin 5-HT3 receptors located on vagal afferent nerves in the gastrointestinal tract and in the chemoreceptor trigger zone of the brain.
2
Blocking serotonin signals: By occupying these receptors, it prevents serotonin from binding and activating the vomiting reflex.
3
Inhibition of vomiting reflex: This blockade reduces the signals sent to the vomiting center, thereby preventing nausea and vomiting.

💡 How to Take ondai 8mg tablet

Strength: Ondansetron 8 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You can take it with or without food.
4Do not crush, chew, or break the tablet unless instructed.
5Follow the dosing schedule strictly for best results.

Dosage Information

Adult DosageThe usual adult dose for prevention of chemotherapy-induced nausea and vomiting is 8 mg taken orally 30 minutes before chemotherapy, followed by 8 mg every 12 hours for 1-2 days. For postoperative nausea and vomiting, 16 mg is taken orally 1 hour before surgery. For radiation-induced nausea, 8 mg is taken orally 1-2 hours before radiation. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be needed based on liver and kidney function. Consult a doctor for personalized dosing.
Renal ImpairmentNo dose adjustment is needed for mild to moderate renal impairment. For severe renal impairment, consult a doctor.
Hepatic ImpairmentFor patients with severe hepatic impairment, the maximum daily dose should not exceed 8 mg. Consult a doctor for personalized dosing.
Maximum Daily DoseThe maximum recommended daily dose is 24 mg for adults, but it may be lower depending on the indication and patient's condition. Always follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with or without food
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase drug levels by affecting liver enzymes.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ondai 8mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Constipation (Common (5-10%))
Increase fiber and fluid intake. Consult doctor if it persists.
Fatigue (Common (5-10%))
Rest and avoid driving if feeling tired. Consult doctor if it interferes with daily activities.
Dizziness (Common (5-10%))
Avoid sudden movements. Do not drive or operate machinery until you know how it affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness. Consult doctor if it persists.

🚨 Serious Side Effects

Severe allergic reactions (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you experience palpitations, chest pain, or fainting.
Serotonin syndrome (Rare (<0.1%))
Seek immediate medical attention if you experience agitation, hallucinations, fever, rapid heart rate, or muscle stiffness.

⚠️ Rare Side Effects

Hypotension
Seek medical attention if you feel faint or dizzy.
QT prolongation
Inform your doctor if you have a history of heart rhythm problems.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Apomorphine Major
Amiodarone Major
Tramadol Moderate
SSRIs Moderate
Cimetidine Minor

🚨 Major Interactions

  • Apomorphine
  • Amiodarone

⚡ Moderate Interactions

  • Tramadol
  • SSRIs

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ondansetron or any component of the formulation","Concomitant use with apomorphine"]

⚠️ Warnings & Precautions

["Use with caution in patients with severe liver impairment.","May cause QT prolongation; use with caution in patients with heart rhythm disorders.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not use if you have a history of allergic reactions to ondansetron."]

🤱 Lactation Safety

This medicine may pass into breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor before use.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include severe drowsiness, dizziness, and irregular heartbeat. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the tablet whole with a glass of water. You can take it with or without food. Avoid alcohol while taking this medicine as it may increase drowsiness. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children. Store at room temperature away from direct sunlight and moisture. Do not use after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Dose adjustment may be needed based on liver and kidney function. Consult a doctor for personalized dosing.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe during pregnancy when prescribed by a doctor, but use only if clearly needed.

🏥 Post-Surgery Considerations

This medicine is often used to prevent and treat postoperative nausea and vomiting. It is usually given before or after surgery as prescribed by your doctor.

🦷 Dental Procedures

This medicine may be used to prevent nausea and vomiting after dental procedures if needed. Consult your dentist or doctor for personalized advice.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Eat small, frequent meals to help with nausea.
😴
Avoid spicy and greasy foods that can upset your stomach.
💧
Get adequate rest.
🧘
Avoid alcohol and smoking.

🏋️ Exercise Considerations

This medicine may cause dizziness or drowsiness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.

🥗 Diet Recommendations

Eat bland, easy-to-digest foods like crackers and toast.
Avoid spicy, greasy, or heavy meals.
Stay well hydrated with clear fluids.
Avoid alcohol and caffeine.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause fatigue, so plan your day accordingly.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately. Your doctor will advise you on when and how to stop.

📅 Long-Term Use Effects

Long-term use of this medicine is generally not recommended unless prescribed by a doctor. It is usually used for short periods. Prolonged use may increase the risk of side effects such as constipation and headache. Regular monitoring may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ginger

Ginger may help reduce nausea and vomiting.

Evidence: Limited
Acupuncture

Acupuncture may help with nausea and vomiting.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccination considerations are established for this medicine. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If you are crossing time zones, consult your doctor about adjusting the dosing schedule. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old woman undergoing chemotherapy for breast cancer
She was prescribed this medicine to prevent nausea and vomiting after chemotherapy. She took it as directed and experienced significant relief from nausea, allowing her to eat and rest comfortably. She reported mild constipation, which was managed with dietary changes.
💡 Lesson: Taking this medicine as prescribed before chemotherapy can effectively prevent nausea and vomiting, improving quality of life during treatment.
👤 A 60-year-old man recovering from abdominal surgery
He was given this medicine to prevent postoperative nausea and vomiting. He experienced no nausea after surgery and was able to start eating sooner. He felt slightly drowsy but it resolved within a few hours.
💡 Lesson: This medicine is effective in preventing postoperative nausea and vomiting, aiding in faster recovery.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after oral administration.

Q: Can I take it with other medicines?

A: Inform your doctor about all other medicines you are taking, as this medicine can interact with several drugs.

Q: Is it safe during pregnancy?

A: This medicine is generally considered safe during pregnancy when prescribed by a doctor. Consult your doctor for personalized advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ondai 8mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of nausea.
    Fact: This medicine is specifically effective for nausea and vomiting caused by certain triggers like chemotherapy, radiation, and surgery. It may not work for all types of nausea.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Ondansetron 8 mg tablet

Brand Alternatives

  • Emeset 8 Tablet
  • Vomikind 8 Tablet
  • Ondem 8 Tablet
  • Emeset 4 Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Ondansetron","class":"5-HT3 antagonist","common_use":"Chemotherapy-induced nausea","onset":"30-60 minutes"},{"medicine":"Granisetron","class":"5-HT3 antagonist","common_use":"Chemotherapy-induced nausea","onset":"30-60 minutes"},{"medicine":"Metoclopramide","class":"Dopamine antagonist","common_use":"Gastroparesis, nausea","onset":"30-60 minutes"}]

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