omniflam aq 150mg injection - Aceclofenac (150mg) medicine

Afesan 150mg Injection: Complete Medicine Guide

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🏭 Embiotic Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, NSAIDs like Aceclofenac are generally avoided during the third trimester due to risk of premature closure of the ductus arteriosus and other complications. Use in the first and second trimester only if clearly needed and after consulting a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for acute pain management.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is omniflam aq 150mg injection used for?

This medicine is an injectable NSAID containing Aceclofenac 150mg. It is used for short-term relief of moderate to severe acute pain and inflammation when oral therapy is not suitable. It works by blocking pain-causing chemicals in the body.

  • Generic Name: Aceclofenac (150mg)
  • Manufacturer: Embiotic Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 omniflam aq 150mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा एक इंजेक्शन है जिसमें एसिफेनाक 150mg होता है। यह मध्यम से गंभीर दर्द और सूजन के इलाज के लिए दी जाती है, खासकर जब मौखिक दवा संभव न हो। यह ऑपरेशन के बाद के दर्द, मांसपेशियों के दर्द, गठिया और अन्य सूजन संबंधी स्थितियों में उपयोग की जाती है। यह दवा केवल डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, लालिमा, मतली, उल्टी, पेट में असुविधा, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, गुर्दे की समस्या, लीवर की समस्या और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, खासकर अगर आपको पेट के अल्सर, गुर्दे या लीवर की बीमारी, हृदय की समस्या या अस्थमा है। इस दवा के साथ शराब न लें। यदि आप एसिफेनाक या अन्य NSAIDs से एलर्जी हैं तो यह दवा न लें। गर्भावस्था के तीसरे तिमाही में इसकी सिफारिश नहीं की जाती है।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 omniflam aq 150mg injection Uses & Benefits

[{"condition":"Post-operative pain","description":"Provides effective relief from moderate to severe pain following surgical procedures, reducing the need for opioid analgesics.","evidence":"Well-established"},{"condition":"Acute musculoskeletal pain","description":"Used for rapid relief of pain and inflammation in conditions like acute low back pain, sprains, and strains.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis flare","description":"Helps control acute exacerbations of joint pain and swelling in rheumatoid arthritis when oral therapy is not suitable.","evidence":"Well-established"},{"condition":"Osteoarthritis flare","description":"Provides short-term relief from severe pain and inflammation in osteoarthritis, especially when oral NSAIDs cannot be taken.","evidence":"Well-established"},{"condition":"Renal colic","description":"May be used for pain relief in renal colic, though other agents are often preferred.","evidence":"Limited"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited and other treatments are preferred.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for severe menstrual cramps when oral NSAIDs are not effective or tolerated.","evidence":"Limited"}]

Primary treatment for: Acute moderate to severe pain

Also treats: Post-operative pain, Musculoskeletal pain, Rheumatoid arthritis, Osteoarthritis

📋 Drug Information

Generic Name(s)Aceclofenac (150mg)
Brand Nameomniflam aq 150mg injection
ManufacturerEmbiotic Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of AdministrationParenteral (intramuscular injection)
StorageStore in a cool, dry place below 25°C. Protect from light. Do not freeze. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only when oral NSAIDs are not feasible or when rapid pain relief is required.
2
Always aspirate before injecting to avoid inadvertent intravascular administration.
3
Use the smallest effective dose for the shortest duration to minimize side effects.
4
Monitor renal and hepatic function in patients with underlying disease or those on prolonged therapy.
5
Consider gastroprotection in patients at high risk of gastrointestinal bleeding.
6
Avoid concomitant use with other NSAIDs or anticoagulants unless clearly necessary.
7
Educate patients to report any signs of bleeding, black stools, or severe abdominal pain immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Acute moderate to severe pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Chronic pain
This medicine is for short-term use only; chronic pain requires other management.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFollowing intramuscular administration, Aceclofenac is rapidly and completely absorbed. The bioavailability is high, and peak plasma concentrations are achieved within 30 to 60 minutes.
DistributionAceclofenac is highly protein-bound (greater than 99%) and distributes well into synovial fluid and inflamed tissues. It has a volume of distribution of approximately 25 liters.
Protein BindingGreater than 99% bound to plasma proteins, primarily albumin.
MetabolismAceclofenac is extensively metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2C9. The main metabolite is 4'-hydroxyaceclofenac, which is inactive.
Half-LifeThe elimination half-life of Aceclofenac is approximately 4 to 4.5 hours.
ExcretionAceclofenac and its metabolites are excreted primarily via the kidneys (approximately 70-80%) and to a lesser extent in feces (about 20%).
BioavailabilityThe intramuscular bioavailability of Aceclofenac is approximately 100% due to complete absorption.
Onset of ActionPain relief typically begins within 30 minutes after intramuscular injection.
Peak Plasma TimePeak plasma concentrations are reached approximately 30 to 60 minutes after intramuscular administration.
Duration of ActionThe analgesic effect lasts for approximately 6 to 8 hours, but may vary depending on the individual and the severity of pain.

How It Works

Aceclofenac is a non-steroidal anti-inflammatory drug that exerts its analgesic, anti-inflammatory, and antipyretic effects by inhibiting the cyclooxygenase (COX) enzymes, primarily COX-2. This inhibition leads to a decrease in the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. By reducing prostaglandin levels, Aceclofenac alleviates pain and swelling at the site of injury or inflammation. It also has some effect on COX-1, which may contribute to gastrointestinal side effects.

Mechanism Steps

1
Inhibition of cyclooxygenase enzymes: Aceclofenac binds to and inhibits the COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: This inhibition leads to decreased production of prostaglandins, prostacyclin, and thromboxanes, which are key mediators of pain, inflammation, and fever.
3
Analgesic and anti-inflammatory effects: The reduction in prostaglandins results in decreased sensitization of pain receptors and reduced vasodilation and edema at the site of inflammation.
4
Antipyretic effect: Prostaglandin reduction in the hypothalamus leads to lowering of elevated body temperature.

💡 How to Take omniflam aq 150mg injection

Strength: Injection: 150mg in a single-use vial.

1This medicine is administered by a healthcare professional only.
2It is given as an intramuscular injection, usually into the buttock or upper arm.
3The injection site will be cleaned with an antiseptic before administration.
4You may feel a brief stinging sensation during the injection.
5After the injection, remain seated for a few minutes to monitor for any immediate reactions.
6Do not massage the injection site vigorously.
7Report any pain, redness, or swelling at the injection site to your nurse or doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 150mg administered intramuscularly once daily or as directed by the physician. The dose may be adjusted based on the severity of pain and the patient's response. It is intended for short-term use only, typically not exceeding 3-5 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the effects of Aceclofenac, especially gastrointestinal and renal side effects. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely.
Renal ImpairmentIn patients with mild to moderate renal impairment (eGFR 30-89 mL/min), no dose adjustment is typically required, but caution is advised. In severe renal impairment (eGFR <30 mL/min), Aceclofenac is contraindicated. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, no dose adjustment is usually necessary, but caution is advised. In severe hepatic impairment, Aceclofenac is contraindicated. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose is 150mg. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing
This medicine is given as an injection, so food timing does not affect its absorption.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and ulcers.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Contact your healthcare provider to reschedule the dose as soon as possible.
💡 Do not attempt to self-administer.
📌 More than half the dosing interval has passed
→ Skip the missed dose and continue with the next scheduled dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of omniflam aq 150mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress to the site. It usually resolves within a few hours.
Nausea (Common (5-10%))
Take small sips of water and rest. If persistent, consult your doctor.
Headache (Common (5-10%))
Rest in a quiet, dark room. Over-the-counter pain relievers may help, but consult your doctor first.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel alert. Lie down if needed.
Abdominal discomfort (Common (5-10%))
Take with food if possible. If pain persists, consult your doctor.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black, tarry stools, vomiting blood, or severe abdominal pain.
Peptic ulcer (Rare (<0.1%))
Report persistent stomach pain or indigestion to your doctor immediately.
Acute kidney injury (Rare (<0.1%))
Seek medical help if you experience decreased urine output, swelling in legs, or fatigue.
Hepatotoxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Anaphylaxis (Very rare (<0.01%))
Call emergency services if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.

⚠️ Rare Side Effects

Blood dyscrasias
Report unusual bruising, bleeding, or infections to your doctor.
Cardiovascular events
Seek immediate care for chest pain, shortness of breath, or weakness.
Severe skin reactions
Stop the medicine and seek immediate medical attention if you develop a rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
Diuretics Moderate
Corticosteroids Moderate
SSRIs Moderate
Other NSAIDs Moderate
Cyclosporine Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Lithium
  • ACE inhibitors
  • Diuretics

⚡ Moderate Interactions

  • Corticosteroids
  • SSRIs
  • Other NSAIDs
  • Cyclosporine

🍷 Alcohol Interaction

Alcohol should be avoided while receiving this medicine as it can increase the risk of stomach bleeding and ulcers. It may also increase the risk of liver toxicity.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Aceclofenac or other NSAIDs","Active peptic ulcer or history of recurrent peptic ulcer","Severe heart failure","Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Cardiovascular risk: NSAIDs may increase the risk of serious cardiovascular thrombotic events. Use with caution in patients with cardiovascular risk factors.","Gastrointestinal risk: Serious GI adverse events, including bleeding, ulceration, and perforation, can occur at any time without warning. Use with caution in patients with a history of GI disease.","Renal risk: Long-term use may lead to renal papillary necrosis and other renal injury. Monitor renal function.","Hepatic risk: May cause borderline elevations of liver enzymes. Rarely, severe hepatic reactions may occur.","Hypersensitivity: Anaphylactic reactions have been reported. Do not use in patients with aspirin-sensitive asthma.","Bleeding risk: May inhibit platelet aggregation and prolong bleeding time. Use with caution in patients with bleeding disorders.","Elderly: Increased risk of adverse effects. Use with caution and monitor closely.","Not for long-term use: This injection is intended for short-term use only. Transition to oral therapy as soon as feasible."]

🤱 Lactation Safety

Aceclofenac is excreted in breast milk in small amounts. It is not recommended during breastfeeding unless the potential benefit outweighs the risk. Consult your doctor before use.

💊 Overdose Management

Overdose of Aceclofenac may cause nausea, vomiting, abdominal pain, gastrointestinal bleeding, headache, dizziness, and renal impairment. There is no specific antidote. Treatment is supportive and symptomatic. Activated charcoal may be administered if the patient presents within 1-2 hours of ingestion. Monitor vital signs, renal and hepatic function, and manage complications. Hemodialysis is not effective in removing Aceclofenac due to high protein binding.

⏰ Missed Dose

This medicine is administered by a healthcare professional, so missed doses are unlikely. If you miss a scheduled dose, contact your doctor or nurse for guidance. Do not attempt to self-administer.

Additional Safety Advice

General Safety

This medicine must be administered only by a qualified healthcare professional. Do not self-administer. Inform your doctor about all your medical conditions, especially if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Avoid alcohol while receiving this medicine as it can increase the risk of stomach bleeding. Do not use this medicine if you are allergic to Aceclofenac or other NSAIDs. It is not recommended during the third trimester of pregnancy. Use with caution in elderly patients and those with bleeding disorders. Regular monitoring of kidney and liver function may be required during prolonged use.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, renal impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Avoid concomitant use with other NSAIDs or anticoagulants.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. NSAIDs like Aceclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester. Discuss alternative pain management options.

🏥 Post-Surgery Considerations

This medicine is often used for post-operative pain. It should be administered under medical supervision. Monitor for bleeding, renal function, and gastrointestinal side effects. Transition to oral analgesics as soon as possible.

🦷 Dental Procedures

If you are undergoing dental procedures, inform your dentist that you are receiving this medicine. It may increase bleeding risk during dental surgery. Your dentist may recommend stopping it temporarily or taking precautions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Engage in regular low-impact exercises like swimming or walking.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods like omega-3 fatty acids in your diet.
🧘
Get adequate sleep to promote healing and pain tolerance.
🌞
Avoid smoking as it can worsen inflammation and delay healing.

🏋️ Exercise Considerations

While taking this medicine, you may experience dizziness or fatigue. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you have pain, consult your doctor before starting any exercise regimen.

🥗 Diet Recommendations

Include omega-3 rich foods such as fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Stay well hydrated by drinking plenty of water.
Consume a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some individuals. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to rest after receiving the injection. Inform your employer if your job requires physical exertion or alertness.

🛑 When to Stop This Medicine

This medicine is for short-term use only. Stop using it when your doctor advises, usually when your pain is controlled or when you can switch to oral medication. Do not stop abruptly if you are on a prescribed regimen without consulting your doctor. If you experience any serious side effects, seek immediate medical attention.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to the risk of serious gastrointestinal, cardiovascular, and renal side effects. Prolonged use can lead to peptic ulcers, kidney impairment, and increased cardiovascular risk. Regular monitoring of renal and hepatic function is advised if used for more than a few days. Always use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain management and improve mobility.

Evidence: Well-established
Acupuncture

May help reduce pain in some individuals, but evidence is mixed.

Evidence: Limited
Topical NSAIDs

Alternative for localized pain with fewer systemic side effects.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider that you are receiving this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use if the solution is discolored or contains particles

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you. Store it in a cool, dry place away from direct sunlight. If traveling by air, carry it in your hand luggage. Check customs regulations for carrying injectable medications. Since this medicine is administered by a healthcare professional, plan ahead to ensure you can receive your dose on time.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with severe knee osteoarthritis pain
He received this medicine as an intramuscular injection for acute pain relief. Within 30 minutes, his pain significantly decreased, allowing him to participate in physical therapy. He was advised to take oral NSAIDs thereafter and to avoid alcohol.
💡 Lesson: This medicine provides rapid pain relief, but it is not a long-term solution. Transition to oral therapy and lifestyle modifications are essential.
👤 A 40-year-old woman post-cesarean section
She was given this medicine for post-operative pain. She experienced good pain control but developed mild nausea, which resolved with antiemetics. She was monitored for bleeding and renal function.
💡 Lesson: This medicine is effective for post-surgical pain, but side effects like nausea are common. Monitoring for bleeding and renal function is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 30 minutes after intramuscular injection.

Q: How long does the effect last?

A: The pain relief usually lasts for 6 to 8 hours, but this can vary.

Q: Can I take this medicine if I have kidney disease?

A: It is not recommended in severe kidney disease. Your doctor will assess your kidney function before prescribing.

Q: Is it safe to use during pregnancy?

A: It is not recommended, especially in the third trimester. Consult your doctor for alternative pain relief.

Q: Can I take other painkillers with this?

A: Do not take other NSAIDs concurrently as it increases the risk of side effects. Consult your doctor before taking any other painkillers.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for omniflam aq 150mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken orally.
    Fact: This medicine is an injection and must be administered by a healthcare professional. It is not for oral use.
  • Myth: This medicine is safe for long-term use.
    Fact: This medicine is intended for short-term use only. Prolonged use can increase the risk of serious side effects.
  • Myth: This medicine is a steroid.
    Fact: This medicine is a non-steroidal anti-inflammatory drug (NSAID), not a steroid.
  • Myth: This medicine can be used for fever.
    Fact: While it has antipyretic properties, it is not primarily used for fever. Other medications are preferred.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 150mg injection

Brand Alternatives

  • Afesan 150mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Aceclofenac injection","class":"NSAID","route":"Intramuscular","onset":"30 minutes","duration":"6-8 hours"},{"medicine":"Diclofenac injection","class":"NSAID","route":"Intramuscular","onset":"15-30 minutes","duration":"4-6 hours"},{"medicine":"Ketorolac injection","class":"NSAID","route":"Intramuscular/Intravenous","onset":"10-15 minutes","duration":"4-6 hours"}]

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