Acenac 150mg Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain or heartburn
- Chest pain, shortness of breath, or difficulty breathing
- Sudden swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
- Severe headache with visual changes or confusion
- Unusual bleeding or bruising
- Rash, blisters, or peeling skin
- High fever with neck stiffness
If experiencing severe symptoms, call emergency services immediately.
What is acenac 150mg injection used for?
This medicine is a prescription NSAID injection containing aceclofenac 150mg. It is given intramuscularly by a healthcare professional to provide rapid relief from moderate to severe pain and inflammation, especially when oral medicines are not suitable. It works by blocking COX enzymes and reducing prostaglandins. It should be used short-term under medical supervision.
- Generic Name: Aceclofenac
- Manufacturer: Medley Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 acenac 150mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा एसिफेनाक 150mg इंजेक्शन के रूप में एक प्रिस्क्रिप्शन दवा है, जिसका उपयोग मध्यम से गंभीर दर्द और सूजन को कम करने के लिए किया जाता है। यह आमतौर पर सर्जरी के बाद, गठिया के दर्द में, और अन्य सूजन संबंधी स्थितियों में दी जाती है जब मरीज मुंह से दवा नहीं ले सकता या तेज असर की आवश्यकता होती है। यह दवा केवल डॉक्टर या नर्स द्वारा इंजेक्शन के माध्यम से दी जाती है। इसे घर पर स्वयं न लगाएं।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, जी मिचलाना, उल्टी, पेट दर्द, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें पेट या आंतों में रक्तस्राव, किडनी की समस्या, लीवर की क्षति, एलर्जी प्रतिक्रिया, और हृदय संबंधी घटनाएं शामिल हो सकती हैं। यदि आपको काला मल, खून की उल्टी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या सीने में दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों के बारे में बताएं, विशेष रूप से पेट के अल्सर, किडनी या लीवर की बीमारी, हृदय रोग, अस्थमा, या रक्तस्राव विकार। साथ ही, अपनी सभी दवाओं के बारे में बताएं, जैसे रक्त पतला करने वाली दवाएं, स्टेरॉयड, एंटीडिप्रेसेंट, और मूत्रवर्धक। इस दवा के साथ शराब का सेवन बिल्कुल न करें। यदि आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो डॉक्टर को पहले बताएं। चक्कर या नींद आने पर वाहन न चलाएं।
💊 acenac 150mg injection Uses & Benefits
[{"condition":"Postoperative pain","description":"Provides rapid relief from moderate to severe pain following surgical procedures, reducing the need for opioid analgesics.","evidence":"Well-established"},{"condition":"Acute exacerbation of osteoarthritis","description":"Helps control pain and inflammation during flare-ups of osteoarthritis when oral therapy is not feasible.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Used for short-term management of pain and swelling in rheumatoid arthritis flare-ups.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Provides symptomatic relief of pain and stiffness in acute episodes.","evidence":"Well-established"},{"condition":"Acute gout","description":"May be used to relieve acute gouty arthritis pain and inflammation when oral NSAIDs are not suitable.","evidence":"Moderate"},{"condition":"Renal colic","description":"Sometimes used for pain relief in kidney stones, though other agents are preferred.","evidence":"Limited"}]
Off-label uses: [{"condition":"Migraine","description":"Occasionally used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for severe menstrual cramps when oral NSAIDs are ineffective.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation
Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Postoperative pain, Acute gout
📋 Drug Information
| Generic Name(s) | Aceclofenac |
| Brand Name | Aceclo Tablet |
| Manufacturer | Medley Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid) |
| Route of Administration | Parenteral (intramuscular injection) |
| Storage | Store below 25°C, protected from light. Do not freeze. Keep out of reach of children. Once opened, use immediately; discard any unused portion. |
| Shelf Life | 24 months from the date of manufacture, unless otherwise specified on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by reversibly inhibiting the cyclooxygenase (COX) enzymes, primarily COX-2, which are involved in the production of prostaglandins. Prostaglandins are chemicals that mediate pain, inflammation, and fever. By blocking these enzymes, this medicine reduces the synthesis of prostaglandins, thereby decreasing pain and swelling at the site of injury or inflammation. It also has antipyretic properties, though it is not primarily used for fever reduction.
Mechanism Steps
💡 How to Take acenac 150mg injection
Strength: 150mg/3mL injection (single-use vial or ampoule)
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 150mg given by intramuscular injection once or twice daily, depending on the severity of pain and the patient's response. The maximum recommended daily dose is 300mg. The duration of treatment should be as short as possible, typically not exceeding 3-5 days, after which oral therapy may be substituted if appropriate. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and other medications. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of aceclofenac, especially gastrointestinal, renal, and cardiovascular side effects. The lowest effective dose should be used for the shortest duration. Renal function should be monitored. Dose adjustment may be necessary based on renal function. Consult a doctor for individualized dosing. |
| Renal Impairment | In patients with mild to moderate renal impairment (eGFR 30-89 mL/min), no specific dose adjustment is usually required, but caution is advised. In severe renal impairment (eGFR <30 mL/min), aceclofenac is contraindicated. Monitor renal function closely. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no specific dose adjustment is usually required, but caution is advised. In severe hepatic impairment, aceclofenac is contraindicated. Monitor liver function tests. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | 300mg per day (150mg twice daily) by intramuscular injection. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of acenac 150mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Major | |
| Diuretics | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Other NSAIDs | Moderate | |
| Antihypertensives | Moderate | |
| Aspirin | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Lithium
- ACE inhibitors and ARBs
- Diuretics
⚡ Moderate Interactions
- Corticosteroids
- SSRIs
- Other NSAIDs
- Antihypertensives (beta-blockers, etc.)
🍷 Alcohol Interaction
Alcohol should be strictly avoided while receiving this medicine. Combining alcohol with aceclofenac increases the risk of stomach ulcers, gastrointestinal bleeding, and liver damage. It can also worsen dizziness and drowsiness. If you consume alcohol regularly, inform your doctor before receiving this injection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to aceclofenac or other NSAIDs","History of asthma, urticaria, or allergic reactions after taking aspirin or other NSAIDs","Active or history of recurrent peptic ulcer or gastrointestinal bleeding","Severe heart failure, ischemic heart disease, peripheral arterial disease, and/or cerebrovascular disease","Severe liver impairment","Severe kidney impairment (eGFR
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with dehydration or hypovolemia.","May mask signs of infection by reducing fever and inflammation.","Can increase risk of cardiovascular events; use lowest effective dose.","May cause fluid retention and edema; caution in heart failure and hypertension.","Should not be given intravenously; intended for intramuscular use only.","Do not use for more than 7 days without medical review.","Inform patients about signs of GI bleeding and when to seek help."]
🤱 Lactation Safety
Aceclofenac is excreted in breast milk in small amounts. It is generally not recommended during breastfeeding, especially for prolonged use, as it may cause adverse effects in the infant. Consult your doctor to weigh the benefits and risks. Alternative pain relief options may be considered.
💊 Overdose Management
Overdose of aceclofenac can cause nausea, vomiting, abdominal pain, dizziness, headache, and in severe cases, gastrointestinal bleeding, kidney failure, liver damage, and coma. There is no specific antidote. Treatment is supportive and symptomatic. Activated charcoal may be given if the patient presents within 1-2 hours of ingestion. Monitor vital signs, renal and liver function, and manage complications. Hemodialysis is not effective due to high protein binding. Seek immediate medical attention if overdose is suspected.
⏰ Missed Dose
This medicine is usually given as a single dose or as a series of injections by a healthcare professional. If you miss a scheduled dose, contact your doctor or nurse as soon as possible. Do not attempt to self-administer a missed dose. Your healthcare provider will determine the best course of action based on your condition and dosing schedule.
Additional Safety Advice
This medicine must be given only by a healthcare professional. Do not attempt to self-administer. Inform your doctor about all your medical conditions, especially if you have a history of stomach ulcers, kidney or liver disease, heart problems, asthma, or bleeding disorders. Also, tell your doctor about all other medicines you are taking, including blood thinners, steroids, antidepressants, and diuretics, as interactions can be dangerous. Avoid alcohol while receiving this medicine, as it increases the risk of stomach bleeding. If you are pregnant, planning pregnancy, or breastfeeding, inform your doctor before receiving this injection. Do not drive or operate heavy machinery if you feel dizzy or drowsy after the injection. Follow your doctor's instructions carefully and report any side effects immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events with NSAIDs. Use the lowest effective dose for the shortest duration. Monitor renal function, blood pressure, and signs of bleeding. Avoid in frail elderly with multiple comorbidities. Consider alternative pain management strategies.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before receiving this medicine. NSAIDs like aceclofenac may interfere with ovulation and are generally avoided during pregnancy, especially in the third trimester. Alternative pain relief options should be considered. Do not use this medicine if you are trying to conceive without medical advice.
🏥 Post-Surgery Considerations
This medicine is often used for postoperative pain relief. It should be administered by a healthcare professional. Monitor for bleeding, especially at the surgical site, as NSAIDs can increase bleeding risk. Ensure adequate hydration and renal function. Use for the shortest duration necessary and transition to oral analgesics as soon as feasible.
🦷 Dental Procedures
If you are scheduled for dental surgery or procedures, inform your dentist about this medicine. NSAIDs can increase bleeding risk during dental procedures. Your dentist may advise stopping the medicine temporarily or taking precautions. Do not stop without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While receiving this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. If you have joint pain, consult a physiotherapist for safe exercises. Do not overexert yourself, as this may worsen inflammation.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually given in a hospital or clinic setting, so you may need to take time off work for the appointment. The pain relief can improve your ability to perform daily activities, but you should not overdo it. Follow your doctor's advice regarding rest and activity.
🛑 When to Stop This Medicine
This medicine is typically prescribed for short-term use. You should stop when your doctor advises, usually when your pain is controlled or you can switch to oral medication. Do not stop abruptly if you are on a prolonged course without consulting your doctor. If you experience any serious side effects, stop the medicine and seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to increased risks of gastrointestinal bleeding, kidney impairment, liver damage, and cardiovascular events. If prolonged therapy is necessary, regular monitoring of renal and hepatic function, blood counts, and blood pressure is essential. The lowest effective dose should be used for the shortest duration. Patients should be reviewed periodically to assess the need for continued treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay be an alternative for localized pain with fewer systemic side effects.
Evidence: Well-establishedSome evidence for pain relief in chronic conditions.
Evidence: ModerateCan help reduce pain and inflammation locally.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine. It is generally safe to receive vaccines while on short-term NSAID therapy, but your doctor will advise based on your overall health.
📦 Storage Guide
✅ DO
Store below 25°C in a cool, dry place
❌ DON'T
Do not freeze the injection
✅ DO
Keep in original packaging to protect from light
❌ DON'T
Do not transfer to another container
✅ DO
Keep out of reach of children
❌ DON'T
Do not use if the solution is discolored or contains particles
✅ DO
Use immediately after opening the ampoule
❌ DON'T
Do not store opened ampoules for later use
✈️ Traveling with This Medicine
This medicine is given by a healthcare professional and is not typically self-administered during travel. If you are prescribed a course of injections while traveling, ensure you carry the original packaging, a copy of your prescription, and a doctor's note explaining the medical need. Store the injection vials in a cool, dry place, away from direct sunlight, and preferably in a insulated bag if traveling in hot climates. Check customs regulations for carrying injectable medicines across borders. It is advisable to have your injections administered at a clinic or hospital at your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine typically starts relieving pain within 30 minutes after intramuscular injection, with peak effects within 1 to 2 hours.
A: The pain relief usually lasts for 12 to 24 hours, depending on the individual and the severity of the condition.
A: It is not recommended in severe kidney disease. In mild to moderate kidney impairment, it may be used with caution and close monitoring. Inform your doctor about your kidney condition.
A: It is generally avoided during pregnancy, especially in the third trimester, due to potential risks to the fetus. Use only if prescribed by a doctor after weighing benefits and risks.
A: You should not take other NSAIDs concurrently as it increases the risk of side effects. Always inform your doctor about all medicines you are taking.
🤔 Common Patient Concerns
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Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Aceclofenac injection is a steroid.
Fact: No, aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID), not a steroid. It reduces pain and inflammation through a different mechanism. - Myth: Aceclofenac injection can be self-administered at home.
Fact: No, it must be given by a healthcare professional because it is an intramuscular injection and requires proper technique and monitoring for adverse reactions. - Myth: Aceclofenac injection is safe for long-term use.
Fact: It is intended for short-term use only. Prolonged use increases the risk of serious gastrointestinal, cardiovascular, and kidney side effects. - Myth: Aceclofenac injection can be taken with alcohol.
Fact: Alcohol should be strictly avoided as it increases the risk of stomach bleeding and liver damage.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac 150mg injection
Brand Alternatives
- Acenac 150mg injection