Ancolam 1.5mg Tablet SR: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Slow, shallow breathing or difficulty breathing
- Severe drowsiness or confusion
- Sudden swelling of face, lips, tongue, or throat
- Suicidal thoughts or self-harm ideation
- Seizures
- Yellowing of skin or eyes
- Severe allergic reaction with rash and itching
- Unusual changes in mood or behavior
If experiencing severe symptoms, call emergency services immediately.
What is nulam 1.5mg tablet sr used for?
This medicine is an oral tablet containing Alprazolam 1.5 mg, a benzodiazepine used for short-term relief of anxiety and panic disorder. It works by enhancing the calming effect of GABA in the brain. It can cause dependence and should only be used under medical supervision.
- Generic Name: Alprazolam (1.5mg)
- Manufacturer: Nusearch Organic
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nulam 1.5mg tablet sr के बारे में (Hindi Summary)
उपयोग: यह दवा अल्प्राजोलम 1.5 मिलीग्राम की गोली है, जिसका उपयोग चिंता विकार और पैनिक डिसऑर्डर के अल्पकालिक उपचार के लिए किया जाता है। यह मस्तिष्क में GABA नामक रसायन के प्रभाव को बढ़ाकर शांति और आराम प्रदान करती है। यह दवा केवल डॉक्टर के परामर्श से ही लेनी चाहिए और इसका सेवन लंबे समय तक नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, थकान, और शरीर में अस्थिरता शामिल हैं। कुछ लोगों को याददाश्त की समस्या, भ्रम, या एकाग्रता में कठिनाई हो सकती है। गंभीर दुष्प्रभावों में सांस लेने में कठिनाई, गंभीर एलर्जी प्रतिक्रिया, और आत्मघाती विचार शामिल हो सकते हैं। यदि कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को केवल डॉक्टर के बताए अनुसार ही लें। डॉक्टर की सलाह के बिना खुराक न बढ़ाएं या कम न करें। इस दवा को लेते समय वाहन चलाने या भारी मशीनरी चलाने से बचें। शराब का सेवन बिल्कुल न करें। अन्य दवाओं के साथ इसका सेवन करने से पहले डॉक्टर को बताएं। इस दवा को अचानक बंद न करें, इससे गंभीर लक्षण हो सकते हैं। इसे बच्चों और पालतू जानवरों से दूर सुरक्षित स्थान पर रखें।
💊 nulam 1.5mg tablet sr Uses & Benefits
[{"condition":"Generalized Anxiety Disorder","description":"This medicine is used for short-term relief of excessive anxiety and worry that interferes with daily life.","evidence":"Well-established"},{"condition":"Panic Disorder","description":"It helps reduce the frequency and intensity of panic attacks and anticipatory anxiety.","evidence":"Well-established"},{"condition":"Anxiety associated with depression","description":"Sometimes used as an adjunct to antidepressants for short-term management of anxiety symptoms.","evidence":"Moderate"},{"condition":"Preoperative anxiety","description":"May be used to reduce anxiety before surgical procedures.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Insomnia","description":"Occasionally prescribed off-label for short-term management of insomnia, though not first-line.","evidence":"Limited"},{"condition":"Irritable Bowel Syndrome","description":"Rarely used off-label for anxiety-related gastrointestinal symptoms.","evidence":"Limited"},{"condition":"Chemotherapy-induced nausea","description":"Sometimes used off-label as an adjunct antiemetic, but evidence is weak.","evidence":"Limited"}]
Primary treatment for: Anxiety disorders
Also treats: Panic disorder, Anxiety associated with depression, Preoperative anxiety
📋 Drug Information
| Generic Name(s) | Alprazolam (1.5mg) |
| Brand Name | nulam 1.5mg tablet sr |
| Manufacturer | Nusearch Organic |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Benzodiazepines |
| Route of Administration | Oral |
| Storage | Store at room temperature between 20°C and 25°C (68°F to 77°F). Keep away from moisture, heat, and direct light. Keep in a secure place, out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Alprazolam binds to the benzodiazepine site on the GABA-A receptor, which is a ligand-gated chloride channel. This binding enhances the inhibitory effect of gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the brain. The increased chloride ion influx hyperpolarizes neurons, reducing their excitability and leading to anxiolytic, sedative, muscle relaxant, and anticonvulsant effects.
Mechanism Steps
💡 How to Take nulam 1.5mg tablet sr
Strength: Alprazolam 1.5 mg immediate-release tablet
Dosage Information
| Adult Dosage | The dosage of this medicine must be individualized by a qualified clinician based on the indication, severity of symptoms, patient's age, weight, renal and hepatic function, and response to therapy. For anxiety, the usual starting dose is 0.25 to 0.5 mg three times daily, with gradual titration as needed. For panic disorder, the starting dose is 0.5 mg three times daily, with increases every 3 to 4 days. The maximum recommended daily dose is 10 mg, but doses above 4 mg per day are rarely needed. Do not exceed the prescribed dose. This medicine is not recommended for long-term use. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the effects of benzodiazepines. The starting dose should be reduced, typically 0.25 mg two to three times daily, and titrated slowly. Use with caution due to increased risk of falls, cognitive impairment, and respiratory depression. |
| Renal Impairment | In patients with renal impairment, the elimination half-life of alprazolam may be prolonged. Dose reduction may be necessary. Monitor closely for excessive sedation. |
| Hepatic Impairment | In patients with hepatic impairment, alprazolam clearance is reduced. The starting dose should be reduced, and titration should be slow. Use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is 10 mg, but doses above 4 mg per day are rarely needed. Individual dosing must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nulam 1.5mg tablet sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioids | Major | |
| Alcohol | Major | |
| Ketoconazole | Major | |
| Carbamazepine | Moderate | |
| Fluoxetine | Moderate | |
| Oral contraceptives | Moderate | |
| Cimetidine | Minor | |
| Antacids | Minor | |
| Rifampin | Moderate | |
| St. John's wort | Moderate |
🚨 Major Interactions
- Opioids (e.g., morphine, oxycodone)
- CNS depressants (e.g., alcohol, barbiturates, antipsychotics)
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
⚡ Moderate Interactions
- CYP3A4 inducers (e.g., carbamazepine, rifampin, St. John's wort)
- Oral contraceptives
- Antidepressants (e.g., fluoxetine, fluvoxamine)
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Alcohol enhances the central nervous system depressant effects of alprazolam, leading to increased sedation, impaired coordination, respiratory depression, and increased risk of overdose. This combination can be dangerous and even life-threatening.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to alprazolam or other benzodiazepines","Severe hepatic impairment","Narrow-angle glaucoma","Myasthenia gravis","Severe respiratory insufficiency","Sleep apnea syndrome","Pregnancy (especially first and third trimesters)","Breastfeeding","History of substance abuse or dependence"]
⚠️ Warnings & Precautions
["This medicine can cause physical and psychological dependence. Use with caution in patients with a history of substance abuse.","Do not stop this medicine abruptly; withdrawal symptoms may occur. Taper gradually under medical supervision.","This medicine may impair mental and physical abilities required for driving or operating machinery.","Concomitant use with opioids may result in profound sedation, respiratory depression, coma, and death.","Use with caution in elderly patients due to increased risk of falls and cognitive impairment.","This medicine may cause anterograde amnesia, especially at higher doses.","Use with caution in patients with hepatic or renal impairment; dose adjustment may be needed.","This medicine may exacerbate depression and increase the risk of suicidal thoughts.","Avoid alcohol and other CNS depressants while taking this medicine.","This medicine is a controlled substance and should be stored securely."]
🤱 Lactation Safety
Alprazolam is excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose of alprazolam can cause severe drowsiness, confusion, impaired coordination, respiratory depression, coma, and death. If overdose is suspected, seek emergency medical attention immediately. The specific benzodiazepine antagonist flumazenil may be used in severe cases, but it should be used with caution as it can precipitate seizures in dependent patients. Supportive care including airway management, oxygen, and intravenous fluids may be required. Monitor vital signs and consciousness level closely.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
This medicine should only be taken as prescribed by a qualified doctor. Do not increase or decrease the dose without medical advice. Avoid driving or operating heavy machinery until you know how this medicine affects you. Do not consume alcohol or use other central nervous system depressants while taking this medicine, as it can increase sedation and respiratory depression. Inform your doctor about all other medications you are taking, especially opioids, antidepressants, and antihistamines. Do not stop this medicine suddenly, as it can cause withdrawal symptoms. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Keep this medicine in a secure place, out of reach of children and pets. Do not share this medicine with others, even if they have similar symptoms. Regular follow-up with your doctor is important to monitor your response and adjust the dose if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of benzodiazepines. They are at increased risk of falls, cognitive impairment, and respiratory depression. The starting dose should be lower, and titration should be slow. Regular monitoring is essential. Avoid long-term use in the elderly if possible.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. This medicine may harm the fetus. Your doctor may recommend alternative treatments or a gradual taper before conception. Do not stop the medicine suddenly without medical advice.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It can interact with anesthetic agents and increase sedation. Your doctor may advise you to stop the medicine temporarily before surgery. Follow your doctor's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It can interact with sedatives or anesthetics used during dental work. Your dentist may need to adjust the treatment plan. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and impaired coordination. Avoid activities that require alertness, such as driving or operating machinery, until you know how it affects you. Exercise may be beneficial for anxiety, but start slowly and avoid high-risk activities. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and impaired concentration, which may affect your ability to work, especially if your job requires alertness or operating machinery. It is important to discuss your work responsibilities with your doctor. You may need to adjust your work schedule or tasks until you know how the medicine affects you. Avoid driving or using heavy equipment until you are sure of the effects.
🛑 When to Stop This Medicine
You should only stop this medicine under the guidance of your doctor. Do not stop abruptly, as it can cause withdrawal symptoms. Your doctor will gradually reduce the dose over weeks or months. If you experience side effects or want to stop, discuss with your doctor who will create a tapering plan. Seek immediate medical attention if you experience seizures or severe withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, meaning you may need higher doses to achieve the same effect. It can also cause physical and psychological dependence. Withdrawal symptoms can occur upon discontinuation, including anxiety, insomnia, tremors, and seizures. Long-term use may also affect memory and cognitive function. Regular monitoring by a doctor is essential, and the medicine should be used for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A type of talk therapy that helps change negative thought patterns and behaviors related to anxiety.
Evidence: Well-establishedAntidepressants that are often first-line for long-term management of anxiety disorders.
Evidence: Well-establishedPractices that can help reduce anxiety and improve emotional well-being.
Evidence: ModeratePhysical activity can reduce anxiety and improve mood.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children and pets
❌ DON'T
Do not share with others
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. This medicine is a controlled substance, so check the laws of your destination country regarding its possession. Carry enough supply for your entire trip and keep it in your carry-on luggage. Store it at room temperature and avoid extreme temperatures. If crossing time zones, consult your doctor about adjusting your dosing schedule. Never share this medicine with others.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose. However, the full therapeutic effect for anxiety may take a few days to a week.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine may harm the fetus. It should only be used during pregnancy if clearly needed and under medical supervision. Consult your doctor if you are pregnant or planning to become pregnant.
A: No, you should not stop this medicine suddenly as it can cause severe withdrawal symptoms, including seizures. Your doctor will gradually reduce the dose under supervision.
🤔 Common Patient Concerns
🔄 Substitutes for nulam 1.5mg tablet sr
View AllAlternative brands with exact same active ingredient:
-
apal sr 1.5mg tabletElikem Pharmaceuticals Pvt Ltd ₹24.00 1.8% COSTLIER
-
zolipax 1.5mg tablet srReliance Formulation Pvt Ltd ₹28.13 19.3% COSTLIER
-
zolam 1.5mg tablet srStadmed Pvt Ltd ₹35.90 52.3% COSTLIER
-
alzocum 1.5mg tabletTaj Pharma India Ltd ₹38.10 61.6% COSTLIER
-
ancolam 1.5mg tablet srSigmund Promedica ₹39.42 67.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: This medicine is intended for short-term use only. Prolonged use can lead to tolerance, dependence, and withdrawal symptoms. - Myth: This medicine can be stopped abruptly without any problems.
Fact: Abrupt discontinuation can cause severe withdrawal symptoms, including seizures. It must be tapered gradually under medical supervision. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol greatly increases the sedative and respiratory depressant effects of this medicine and can be life-threatening. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine may harm the fetus and should only be used during pregnancy if clearly needed and under medical supervision.
🔄 Alternative Options
Generic Alternatives
- Alprazolam
Brand Alternatives
- Ancolam 1.5mg Tablet SR