Apal SR 1.5mg Tablet - Uses, Price, Side Effects
What is apal sr 1.5mg tablet used for?
Apal SR 1.5mg Tablet contains Alprazolam, a benzodiazepine used to treat anxiety disorders and panic attacks. It works by enhancing the effect of GABA, a natural chemical in the brain that promotes calmness and relaxation. This extended-release formulation provides sustained symptom control throughout the day.
- Generic Name: Alprazolam
- Manufacturer: Elikem Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ apal sr 1.5mg tablet Uses & Benefits
Generalized anxiety disorder (GAD), Panic disorder with or without agoraphobia, Short-term relief of anxiety symptoms
Off-label uses: Insomnia (short-term), Premenstrual dysphoric disorder (PMDD), Cataplexy associated with narcolepsy
๐ Drug Information
| Generic Name(s) | Alprazolam |
| Brand Name | Alprax 0.25 Tablet |
| Manufacturer | Elikem Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Benzodiazepines |
| Route of Administration | Oral |
| Storage | Store at 20โ25ยฐC (68โ77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Enhances the inhibitory effect of gamma-aminobutyric acid (GABA) at GABA-A receptors, increasing chloride ion influx and neuronal hyperpolarization.
Mechanism Steps
๐ก How to Take apal sr 1.5mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of apal sr 1.5mg tablet
โ Common Side Effects
- Drowsiness
- Dizziness
- Fatigue
- Ataxia
- Slurred speech
- Memory impairment
๐จ Serious Side Effects
- Respiratory depression
- Paradoxical reactions (e.g., agitation, aggression)
- Physical dependence and withdrawal syndrome
- Seizures (with abrupt discontinuation)
โ ๏ธ Rare Side Effects
- Jaundice
- Blood dyscrasias (e.g., agranulocytosis)
- Anaphylaxis
- Angle-closure glaucoma
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Increased CNS depression and sedation |
| Opioid analgesics | Major | Additive CNS depression, risk of respiratory depression |
| Ketoconazole | Moderate | Increased alprazolam levels, prolonged sedation |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir) โ increased alprazolam levels
- CYP3A4 inducers (e.g., carbamazepine, rifampin) โ decreased alprazolam levels
- Opioids (e.g., morphine, oxycodone) โ additive CNS depression, risk of respiratory depression
- Other benzodiazepines โ additive sedation
โก Moderate Interactions
- Alcohol โ additive CNS depression
- Antidepressants (e.g., SSRIs, MAOIs) โ potential for increased sedation
- Antipsychotics โ additive sedation
- Muscle relaxants โ enhanced muscle relaxation
โน๏ธ Minor Interactions
- Oral contraceptives โ may increase alprazolam levels
- Cimetidine โ increased alprazolam levels
- Grapefruit juice โ increased alprazolam levels
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase alprazolam levels; food delays absorption but does not significantly affect bioavailability.
๐ท Alcohol Interaction
Severe additive CNS depression; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to alprazolam or other benzodiazepines, Acute narrow-angle glaucoma, Severe respiratory insufficiency, Myasthenia gravis, Concurrent use with opioids (except in monitored settings)
๐ Monitoring Parameters
CNS depression (sedation, dizziness), Respiratory rate, Blood pressure, Liver function tests (LFTs), Renal function tests (RFTs), Complete blood count (CBC) with long-term use
๐คฑ Lactation Safety
Low risk; alprazolam is excreted in breast milk; monitor infant for sedation and feeding difficultie
๐ Overdose Management
Supportive care; flumazenil (benzodiazepine antagonist) may be used but with caution due to risk of seizures.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; skip missed dose if near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for apal sr 1.5mg tablet
View AllAlternative brands with exact same active ingredient (Alprazolam (1.5mg)):
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nulam 1.5mg tablet srNusearch Organic โน23.57 1.8% CHEAPER
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zolipax 1.5mg tablet srReliance Formulation Pvt Ltd โน28.13 17.2% COSTLIER
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zolam 1.5mg tablet srStadmed Pvt Ltd โน35.90 49.6% COSTLIER
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alzocum 1.5mg tabletTaj Pharma India Ltd โน38.10 58.8% COSTLIER
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ancolam 1.5mg tablet srSigmund Promedica โน39.42 64.3% COSTLIER
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notence 1.5mg tablet srCrescent Therapeutics Ltd โน41.53 73% COSTLIER
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alzopax 1.5mg tablet srLa Pharmaceuticals โน44.13 83.9% COSTLIER
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alprax 1.5mg tablet srTorrent Pharmaceuticals Ltd โน47.91 99.6% COSTLIER
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ariprax 1.5mg tablet srRyon Pharma โน48.50 102.1% COSTLIER
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alzolam 1.5 mg tablet srSun Pharmaceutical Industries Ltd โน51.00 112.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.