novadine pessaries - Clotrimazole (200mg) + Lactobacillus (150Million spores) medicine

Ginlac-v Vaginal Tablet: A Complete Guide To Uses, Dosage, And Safety

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🏭 Radico Remedies 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for clotrimazole in vaginal candidiasis; supportive for Lactobacillus in restoring vaginal flora.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: rash, hives, swelling of face, lips, or tongue, difficulty breathing.
  • Severe vaginal irritation, pain, or ulceration.
  • High fever with chills and severe pelvic pain.
  • Foul-smelling vaginal discharge that does not improve with treatment.
  • Symptoms that worsen or do not improve after 7 days of treatment.
  • Bleeding between periods or after intercourse.
  • Painful urination that persists or worsens.

If experiencing severe symptoms, call emergency services immediately.

What is novadine pessaries used for?

This medicine is a vaginal tablet containing clotrimazole (an antifungal) and Lactobacillus (a probiotic). It treats vaginal yeast infections and helps restore healthy vaginal bacteria. It is inserted into the vagina at bedtime for 6-7 days.

  • Generic Name: Clotrimazole (200mg) + Lactobacillus (150Million spores)
  • Manufacturer: Radico Remedies
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 novadine pessaries के बारे में (Hindi Summary)

उपयोग: यह दवा योनि में होने वाले फंगल संक्रमण (कैंडिडिआसिस) के इलाज के लिए इस्तेमाल की जाती है। इसमें क्लोट्रिमाजोल और लैक्टोबैसिलस होते हैं, जो संक्रमण को खत्म करने और योनि के प्राकृतिक बैक्टीरिया को संतुलित करने में मदद करते हैं। यह दवा योनि में डाली जाती है, आमतौर पर रात को सोने से पहले, 6 से 7 दिनों तक।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में योनि में जलन, खुजली, या असुविधा शामिल हो सकते हैं। कुछ महिलाओं को स्राव में वृद्धि या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चेहरे या होंठों पर सूजन, या गंभीर एलर्जी के लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा का उपयोग करने से पहले अपने डॉक्टर को बताएं यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या किसी भी दवा से एलर्जी है। उपचार के दौरान संभोग से बचें। टैम्पोन या डूश का उपयोग न करें। दवा डालने से पहले और बाद में हाथ धोएं। यदि लक्षण 7 दिनों के बाद भी बने रहते हैं, तो डॉक्टर से मिलें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 novadine pessaries Uses & Benefits

  • [{"condition":"Vaginal candidiasis (yeast infection)","description":"This medicine is used to treat vaginal yeast infections caused by Candida albicans and other Candida species.
  • It provides antifungal action and helps restore normal vaginal flora.","evidence":"Well-established"},{"condition":"Vaginal flora imbalance","description":"The Lactobacillus component helps to re-establish a healthy vaginal microbiome, which can prevent recurrent infections.","evidence":"Supportive"}]

Off-label uses: []

Primary treatment for: Vaginal candidiasis

Also treats: Vaginal flora imbalance, Recurrent vaginal yeast infections

📋 Drug Information

Generic Name(s)Clotrimazole (200mg) + Lactobacillus (150Million spores)
Brand Namenovadine pessaries
ManufacturerRadico Remedies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationVaginal
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original packaging.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Insert the tablet at bedtime to allow it to stay in place and work overnight.
2
Complete the full course of treatment even if symptoms improve after a few days.
3
Avoid sexual intercourse during treatment to prevent irritation and reinfection.
4
Do not use tampons or douches while using this medicine, as they can interfere with treatment.
5
Wear loose, breathable cotton underwear to help keep the area dry and prevent irritation.
6
If you are pregnant, consult your doctor before using this medicine.
7
If symptoms persist after completing the course, see your doctor for further evaluation.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Vaginal itching
This medicine is commonly prescribed for this.
Likely Use
✅
Vaginal discharge
This medicine helps treat abnormal vaginal discharge due to yeast infection.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Pelvic pain
Pelvic pain may indicate a different condition; consult a doctor.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionClotrimazole is minimally absorbed systemically after vaginal administration. Only about 3-10% of the dose is absorbed, and peak plasma levels are very low. Lactobacillus is not absorbed; it acts locally in the vagina.
DistributionClotrimazole distributes locally in the vaginal tissues. Systemically absorbed clotrimazole is widely distributed but plasma concentrations are negligible after vaginal use. Lactobacillus remains in the vaginal lumen and on the epithelial surface.
Protein BindingClotrimazole is approximately 90% bound to plasma proteins, but this is not clinically relevant after vaginal administration due to minimal systemic absorption.
MetabolismAny clotrimazole absorbed systemically is metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4. Lactobacillus is not metabolized; it remains in the vagina.
Half-LifeThe elimination half-life of clotrimazole after vaginal administration is not well established due to minimal systemic absorption. For systemically absorbed clotrimazole, the half-life is approximately 2 hours.
ExcretionAbsorbed clotrimazole is excreted mainly in the feces as inactive metabolites, with a small amount in urine. Lactobacillus is cleared naturally through vaginal secretions.
BioavailabilityThe systemic bioavailability of clotrimazole after vaginal administration is low, approximately 3-10%. Lactobacillus is not systemically bioavailable.
Onset of ActionSymptomatic relief of vaginal itching and discharge may begin within 1-2 days of starting treatment, but complete eradication of the infection requires completing the full course.
Peak Plasma TimePeak plasma concentrations of clotrimazole after vaginal administration are very low and are typically reached within 6-12 hours. However, systemic levels are not clinically significant.
Duration of ActionThe local antifungal effect of clotrimazole lasts for several hours after insertion. Lactobacillus may persist and colonize the vagina for days to weeks, providing ongoing protection.

How It Works

This medicine combines two active ingredients. Clotrimazole is an imidazole antifungal that inhibits the synthesis of ergosterol, a vital component of the fungal cell membrane. This leads to increased permeability and leakage of cellular contents, causing fungal cell death. Lactobacillus is a probiotic that produces lactic acid, helping to maintain an acidic vaginal pH (around 3.8-4.5) that inhibits the growth of pathogenic organisms and promotes a healthy vaginal environment.

Mechanism Steps

1
Clotrimazole inhibits ergosterol synthesis: Clotrimazole binds to and inhibits the fungal enzyme 14α-demethylase, blocking the conversion of lanosterol to ergosterol, a key component of the fungal cell membrane.
2
Fungal cell membrane damage: The lack of ergosterol leads to a weakened cell membrane, causing leakage of essential cellular components and ultimately fungal cell death.
3
Lactobacillus colonization: Lactobacillus adheres to the vaginal epithelium and produces lactic acid, lowering the vaginal pH and creating an environment hostile to Candida and other pathogens.
4
Restoration of vaginal flora: The combined action reduces the yeast population and promotes the growth of beneficial bacteria, helping to restore the natural balance of the vaginal ecosystem.

💡 How to Take novadine pessaries

Strength: Vaginal tablet containing Clotrimazole 200 mg and Lactobacillus 150 million spores.

1Wash your hands thoroughly with soap and water before handling the tablet.
2Remove the tablet from its packaging just before use.
3Lie on your back with your knees bent and feet flat on the floor, or stand with one foot on a chair.
4Insert the tablet high into the vagina using the applicator provided, or with a clean finger if no applicator is available.
5Push the tablet as far as it will go comfortably. Do not force it.
6Withdraw the applicator (if used) and wash it with warm soapy water, then rinse and dry.
7Wash your hands again after insertion.
8Use at bedtime to prevent the tablet from falling out.

Dosage Information

Adult DosageThe usual adult dose is one vaginal tablet inserted high into the vagina at bedtime for 6 to 7 consecutive days, or as prescribed by your doctor. The dose and duration may vary depending on the severity of the infection and your medical history. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageNo specific dosage adjustments are required for elderly patients. However, consult your doctor for proper evaluation and dosing.
Renal ImpairmentNo dosage adjustment is required for patients with renal impairment due to minimal systemic absorption. However, consult your doctor if you have severe kidney disease.
Hepatic ImpairmentNo dosage adjustment is required for patients with hepatic impairment due to minimal systemic absorption. However, consult your doctor if you have severe liver disease.
Maximum Daily DoseOne vaginal tablet per day, or as prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

No specific food interactions
No restrictions
This medicine is applied locally and does not interact with food.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of novadine pessaries

✅ Common Side Effects

Vaginal burning or irritation (Common (1-10%))
This usually resolves on its own. If it persists or worsens, consult your doctor.
Vaginal itching (Common (1-10%))
May be due to the infection itself. If it continues after a few days, contact your healthcare provider.
Increased vaginal discharge (Common (1-10%))
This is often the tablet dissolving and coming out. It is not a cause for concern.
Headache (Uncommon (0.1-1%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, hives, swelling of the face, lips, or tongue, or difficulty breathing.
Severe vaginal irritation or ulceration (Rare (<0.1%))
Stop using the medicine and consult your doctor immediately.

⚠️ Rare Side Effects

Abdominal cramping
If cramping is severe or persistent, consult your doctor.
Skin rash
Discontinue use and consult your doctor if rash develops.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Tacrolimus Moderate
Warfarin Moderate

⚡ Moderate Interactions

  • Tacrolimus
  • Warfarin

🍷 Alcohol Interaction

There is no known interaction between alcohol and this medicine. However, alcohol may worsen vaginal irritation or discomfort. It is advisable to limit alcohol consumption while treating a vaginal infection.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to clotrimazole or any other ingredient in this medicine.","Use in children under 12 years of age without medical supervision.","Not for oral use; do not swallow the tablet."]

⚠️ Warnings & Precautions

["Do not use this medicine if you have never had a vaginal yeast infection diagnosed by a doctor, as other conditions may mimic yeast infections.","If symptoms do not improve within 3 days or persist after 7 days, consult your doctor.","Avoid contact with eyes, ears, and mouth.","Do not use tampons, douches, or spermicides during treatment.","Avoid sexual intercourse during treatment as it may reduce efficacy and cause irritation.","If you are pregnant or breastfeeding, consult your doctor before use.","Keep out of reach of children.","Do not use if the tablet is discolored or damaged."]

🤱 Lactation Safety

This medicine is unlikely to affect a breastfed infant because systemic absorption is minimal. However, consult your doctor before use if you are breastfeeding.

💊 Overdose Management

Overdose with this medicine is unlikely due to its vaginal route of administration. If accidental ingestion occurs, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, and abdominal pain. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before using this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine if you have a history of allergy to clotrimazole or other azole antifungals. Avoid sexual intercourse during treatment, as it may reduce effectiveness and cause irritation. Do not use tampons or douches while using this medicine. Wash your hands thoroughly before and after inserting the tablet. If symptoms persist after completing the course, consult your doctor. Keep this medicine out of reach of children. Do not use it for any condition other than the one prescribed. If you are using a vaginal applicator, clean it properly after each use. Avoid using latex condoms or diaphragms during treatment, as the tablet may weaken them.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly women may be more prone to vaginal dryness and irritation. Use the tablet with care and consider using a water-based lubricant if needed. Consult your doctor if you have any concerns.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. Vaginal clotrimazole is generally considered safe, but it is best to use it under medical supervision. Treating a yeast infection before conception can improve comfort and reduce risks.

🏥 Post-Surgery Considerations

If you have recently had vaginal or pelvic surgery, consult your doctor before using this medicine. It may not be suitable immediately after surgery due to the risk of irritation or infection.

🦷 Dental Procedures

This medicine is for vaginal use and does not affect dental procedures. No special precautions are needed.

💚 Lifestyle Tips for Better Results

🏃
Wear loose, breathable cotton underwear to keep the vaginal area dry.
🥗
Avoid using scented soaps, douches, or feminine sprays that can irritate the vagina.
😴
Change out of wet swimsuits or damp clothing promptly.
💧
Practice good hygiene, but avoid over-washing the vaginal area.
🧘
Include probiotics in your diet, such as yogurt with live cultures, to support vaginal health.
🌞
Manage stress and get adequate sleep to support your immune system.
🚭
Avoid excessive sugar intake, as high sugar levels can promote yeast growth.

🏋️ Exercise Considerations

There are no specific exercise restrictions while using this medicine. However, if you experience discomfort or irritation, you may want to avoid strenuous activities until symptoms improve. Listen to your body and rest if needed.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt, kefir, and fermented foods.
Reduce intake of sugary and processed foods that can promote yeast growth.
Stay well hydrated by drinking plenty of water.
Eat a balanced diet rich in fruits, vegetables, and whole grains.
Limit alcohol and caffeine, which can worsen irritation.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to work or drive. However, if you experience dizziness or discomfort, avoid driving or operating heavy machinery until you feel better. You can continue your normal daily activities, but avoid sexual intercourse during treatment.

🛑 When to Stop This Medicine

Stop using this medicine if you experience a severe allergic reaction or if your symptoms worsen. Do not stop treatment early even if symptoms improve, as this may lead to recurrence. If you have completed the full course and symptoms persist, consult your doctor before using more.

📅 Long-Term Use Effects

Long-term use of this medicine is not typically recommended unless advised by a doctor. Prolonged use may lead to changes in vaginal flora or rare systemic effects. If you have recurrent yeast infections, your doctor may investigate underlying causes such as diabetes or immune disorders. Regular follow-up is important to ensure the infection is fully resolved and to prevent complications.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral antifungal medication

A single dose of oral fluconazole may be prescribed for uncomplicated yeast infections, but it is not suitable for pregnant women.

Evidence: Well-established
Boric acid vaginal suppositories

Sometimes used for recurrent yeast infections, but not recommended during pregnancy.

Evidence: Limited
Probiotic supplements

Oral or vaginal probiotics may help prevent recurrent yeast infections.

Evidence: Supportive

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label. Keep it in your carry-on luggage to avoid extreme temperatures. If traveling across time zones, continue taking the dose at bedtime local time. Store at room temperature and avoid leaving it in a hot car. If you are traveling for an extended period, ensure you have enough supply to complete the course. Customs may require a prescription copy for controlled substances, but this medicine is generally not restricted.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with recurrent vaginal yeast infections
She had been suffering from itching and discharge for several months. Her doctor prescribed this medicine for 7 days. She used it at bedtime and noticed significant relief by day 3. She completed the full course and also started taking probiotics orally. She has not had a recurrence in 6 months.
💡 Lesson: Completing the full course and addressing underlying factors can prevent recurrent yeast infections.
👤 A 28-year-old pregnant woman in her second trimester
She developed a vaginal yeast infection and was worried about using medication. Her doctor assured her that this medicine is safe in pregnancy. She used it for 7 days and her symptoms resolved. She delivered a healthy baby.
💡 Lesson: Vaginal clotrimazole is considered safe in pregnancy when used as directed by a healthcare provider.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief within 1-2 days, but it is important to complete the full 6-7 day course to fully clear the infection.

Q: Can I use this medicine during my periods?

A: It is generally not recommended to use vaginal tablets during your period, as menstrual flow may wash out the medicine. Wait until your period is over to start treatment, unless your doctor advises otherwise.

Q: Is it safe to use this medicine while pregnant?

A: Clotrimazole vaginal tablets are considered safe during pregnancy when used as directed by your doctor. However, always consult your healthcare provider before using any medicine during pregnancy.

Q: Can I have sex while using this medicine?

A: It is advisable to avoid sexual intercourse during treatment, as it may reduce the effectiveness of the medicine and cause irritation.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Does this medicine cause discharge?

A: The tablet may dissolve and come out as a white discharge. This is normal and not a cause for concern.

Q: Can I use this medicine with a condom?

A: Vaginal tablets may weaken latex condoms and diaphragms. Avoid using them during treatment or use an alternative method of contraception.

Q: How should I store this medicine?

A: Store at room temperature between 15°C and 30°C, away from light and moisture. Keep in the original packaging.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe to use during periods?
  • Can I use it with a condom?

🔄 Substitutes for novadine pessaries

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Vaginal yeast infections are caused by poor hygiene.
    Fact: Yeast infections are not caused by poor hygiene. They occur due to an imbalance in the natural vaginal flora, which can be triggered by antibiotics, hormonal changes, or a weakened immune system.
  • Myth: You can treat a yeast infection with yogurt.
    Fact: While yogurt contains probiotics, it is not a proven treatment for vaginal yeast infections. This medicine contains specific strains of Lactobacillus and clotrimazole that are clinically effective.
  • Myth: Once symptoms go away, you can stop treatment.
    Fact: It is important to complete the full course of treatment even if symptoms improve, to ensure the infection is fully cleared and to prevent recurrence.

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Clotrimazole + Lactobacillus","route":"Vaginal","duration":"6-7 days","notes":"Combines antifungal and probiotic for comprehensive treatment."},{"medicine":"Clotrimazole vaginal tablet","active_ingredients":"Clotrimazole only","route":"Vaginal","duration":"6-7 days","notes":"Antifungal only, no probiotic."},{"medicine":"Fluconazole oral capsule","active_ingredients":"Fluconazole","route":"Oral","duration":"Single dose","notes":"Systemic treatment, not for pregnant women."}]

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