Nosardi Plus Tablet: Complete Guide To Uses, Side Effects, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of skin or eyes
- Dark urine
- Severe abdominal pain
- Difficulty breathing
- Swelling of face, lips, or throat
- Chest pain or irregular heartbeat
- Severe headache with blurred vision
If experiencing severe symptoms, call emergency services immediately.
What is Nosardi Plus Tablet used for?
This medicine is a combination of Paracetamol and Phenylephrine used for temporary relief of cold symptoms like nasal congestion, headache, and fever. It works by reducing pain and fever and shrinking nasal blood vessels.
- Generic Name: Paracetamol (325mg) + Phenylephrine (10mg)
- Manufacturer: Liza Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Nosardi Plus Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और फेनाइलएफ्रिन का संयोजन है, जिसका उपयोग सर्दी-जुकाम के लक्षणों जैसे नाक बंद होना, सिरदर्द, बदन दर्द और बुखार से राहत के लिए किया जाता है। यह दर्द और बुखार को कम करती है और नाक के रक्त वाहिकाओं को सिकोड़कर नाक की भीड़ को कम करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में परेशानी, सिरदर्द, चक्कर आना, बेचैनी और नींद न आना शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी, लीवर की क्षति, और रक्तचाप में वृद्धि शामिल हो सकती है। यदि आपको पीलिया, गहरे रंग का मूत्र, गंभीर पेट दर्द, सांस लेने में कठिनाई, या चेहरे और गले में सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: अनुशंसित खुराक से अधिक न लें। इस दवा के साथ अन्य पैरासिटामोल युक्त उत्पाद न लें। बिना डॉक्टर की सलाह के 5 दिन से अधिक न लें। शराब से बचें क्योंकि इससे लीवर की क्षति का खतरा बढ़ सकता है। उच्च रक्तचाप, हृदय रोग, थायरॉइड विकार, मधुमेह, या लीवर/किडनी की समस्या वाले लोगों को सावधानी बरतनी चाहिए और चिकित्सकीय देखरेख में ही लेना चाहिए। यदि आपको किसी भी घटक से एलर्जी है तो यह दवा न लें। बच्चों की पहुंच से दूर रखें।
💊 Nosardi Plus Tablet Uses & Benefits
[{"condition":"Common cold","description":"Provides temporary relief of nasal congestion, headache, body ache, and fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Helps reduce nasal congestion and associated headache.","evidence":"Moderate"},{"condition":"Sinusitis","description":"May relieve nasal congestion and pain in sinusitis.","evidence":"Limited"}]
Off-label uses: []
Primary treatment for: Common cold
Also treats: Allergic rhinitis, Sinusitis
📋 Drug Information
| Generic Name(s) | Paracetamol (325mg) + Phenylephrine (10mg) |
| Brand Name | Nosardi Plus Tablet |
| Manufacturer | Liza Life Sciences |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. |
| Shelf Life | 24 months from date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Paracetamol works centrally to reduce pain and fever by inhibiting prostaglandin synthesis in the brain. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that causes vasoconstriction in the nasal mucosa, reducing swelling and congestion.
Mechanism Steps
💡 How to Take Nosardi Plus Tablet
Strength: Tablet: Paracetamol 325 mg + Phenylephrine 10 mg
Dosage Information
| Adult Dosage | The usual adult dose is 1 tablet every 4 to 6 hours as needed, not to exceed 6 tablets in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of Phenylephrine and Paracetamol. Use with caution and consult a doctor for appropriate dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. Consult a doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor. |
| Maximum Daily Dose | Paracetamol: 3250 mg (10 tablets) per day; Phenylephrine: 60 mg (6 tablets) per day. Do not exceed 6 tablets in 24 hours. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Nosardi Plus Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Warfarin | Major | |
| Beta-blockers | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Warfarin
⚡ Moderate Interactions
- Beta-blockers
- Tricyclic antidepressants
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine as it can increase the risk of liver damage, especially with Paracetamol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe liver disease","Uncontrolled hypertension","Severe coronary artery disease","Use with MAOIs","Hypersensitivity to any component"]
⚠️ Warnings & Precautions
["Do not exceed recommended dose.","Avoid alcohol.","Use with caution in patients with hypertension, heart disease, diabetes, thyroid disorders, and liver/kidney impairment.","Do not use for more than 5 days without medical advice.","Keep out of reach of children."]
🤱 Lactation Safety
Paracetamol is considered safe during breastfeeding. Phenylephrine may pass into breast milk and could affect the infant; consult your doctor before use.
💊 Overdose Management
Seek immediate medical attention. Overdose with Paracetamol can cause severe liver damage. Treatment includes activated charcoal, N-acetylcysteine, and supportive care. Phenylephrine overdose may cause hypertension and arrhythmias; manage symptomatically.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Do not exceed the recommended dose. Avoid taking other products containing Paracetamol while on this medicine to prevent overdose. Do not use for more than 5 days without consulting a doctor. Avoid alcohol as it may increase the risk of liver damage. People with high blood pressure, heart disease, thyroid disorders, diabetes, or liver/kidney problems should use with caution and only under medical supervision. Do not take this medicine if you are allergic to any of its ingredients. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of Phenylephrine and Paracetamol. Use with caution and consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. Paracetamol is generally considered safe, but Phenylephrine should be used with caution.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with anesthetics or other medications.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise while you have a cold or fever. Rest is important for recovery. Consult your doctor before resuming exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to rest at home when you have a cold.
🛑 When to Stop This Medicine
Stop taking this medicine if symptoms persist for more than 5 days or if you experience any serious side effects. Consult your doctor before stopping if you have been taking it regularly.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of Paracetamol can increase the risk of liver damage, especially with alcohol. Phenylephrine may cause rebound congestion if used for more than 5 days. Regular monitoring of liver function and blood pressure may be required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps relieve nasal congestion naturally.
Evidence: Well-establishedMoisturizes nasal passages and reduces congestion.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30-60 minutes after taking it.
A: It is best taken with food to reduce stomach upset.
A: Pediatric dosing is not established. Consult a pediatrician.
🤔 Common Patient Concerns
🔄 Substitutes for Nosardi Plus Tablet
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the recommended dose can cause serious liver damage and other side effects.
🔄 Alternative Options
Generic Alternatives
- Paracetamol + Phenylephrine combinations