Jagquin 50mg Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blurred vision, difficulty reading, flashing lights, or loss of peripheral vision.
- Fainting, palpitations, chest pain, or shortness of breath.
- Confusion, sweating, shakiness, or loss of consciousness suggesting low blood sugar.
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Unusual bruising, bleeding, fever, or persistent sore throat.
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- New muscle weakness, difficulty walking, or loss of reflexes.
- Seizures or sudden severe headache with visual changes.
If experiencing severe symptoms, call emergency services immediately.
What is nivaquine p 50mg suspension used for?
This medicine is an oral chloroquine syrup used to treat and prevent malaria caused by chloroquine-sensitive parasites and to treat certain autoimmune conditions such as rheumatoid arthritis and lupus. It works by killing malaria parasites in the blood and by calming parts of the immune system. It must be taken exactly as prescribed and requires regular monitoring, especially for eye and heart safety.
- Generic Name: Chloroquine (50mg)
- Manufacturer: Abbott
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nivaquine p 50mg suspension के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरोक्वीन नामक एंटीमलेरियल दवा का सिरप रूप है, जिसका उपयोग क्लोरोक्वीन-संवेदनशील मलेरिया के इलाज और रोकथाम के लिए किया जाता है। यह रूमेटॉइड आर्थराइटिस और ल्यूपस जैसी कुछ ऑटोइम्यून बीमारियों में भी दी जाती है। यह मलेरिया परजीवी को खून में नष्ट करती है और शरीर की प्रतिरक्षा प्रणाली के कुछ हिस्सों को शांत करती है। इस दवा का उपयोग डॉक्टर की सलाह के बिना कभी न करें, क्योंकि इसकी खुराक और अवधि बीमारी के अनुसार अलग होती है। लंबे समय तक उपयोग करने पर आंखों की नियमित जांच बहुत जरूरी है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट में असहजता, भूख कम लगना, सिरदर्द, चक्कर आना और धुंधला दिखना शामिल हैं। ये आमतौर पर हल्के होते हैं और शरीर के अभ्यस्त होने पर कम हो जाते हैं। लंबे समय तक उपयोग करने पर आंखों की रेटिना को नुकसान, मांसपेशियों में कमजोरी, सुनने में कठिनाई, त्वचा पर दाने और खून से जुड़ी समस्याएं हो सकती हैं। कभी-कभी दिल की धड़कन अनियमित होना, बहुत कम शुगर होना या गंभीर एलर्जी भी हो सकती है। कोई भी नई दिक्कत होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और खुराक खुद से न बदलें। सिरप को मापने के लिए दिए गए कप या सिरिंज का ही उपयोग करें। अगर पेट खराब लगे तो इसे भोजन या दूध के साथ लें। लंबे समय तक इस दवा का उपयोग कर रहे हैं तो आंखों की नियमित जांच कराएं। अपने डॉक्टर को अपनी सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। इस दवा के साथ शराब न लें। बुखार या मलेरिया की आशंका होने पर बिना जांच के इस दवा का सेवन न करें। गर्भवती महिलाएं, गर्भधारण की योजना बनाने वाली महिलाएं और स्तनपान कराने वाली माताएं डॉक्टर से सलाह लें।
💊 nivaquine p 50mg suspension Uses & Benefits
[{"condition":"Uncomplicated malaria due to chloroquine-sensitive Plasmodium species","description":"This medicine is used to treat malaria caused by parasite strains that remain sensitive to chloroquine, including Plasmodium vivax, Plasmodium ovale, Plasmodium malariae, and chloroquine-sensitive Plasmodium falciparum.","evidence":"Well-established"},{"condition":"Malaria chemoprophylaxis in selected travellers","description":"This medicine may be prescribed to prevent malaria in travellers visiting regions where chloroquine-sensitive malaria transmission occurs, but it is not effective in areas with chloroquine-resistant parasites.","evidence":"Well-established in selected settings"},{"condition":"Rheumatoid arthritis","description":"This medicine is used as a disease-modifying antirheumatic drug in some patients with mild to moderate rheumatoid arthritis, often as part of a broader treatment plan.","evidence":"Established"},{"condition":"Systemic lupus erythematosus","description":"This medicine can help control skin and joint symptoms and reduce flares in selected patients with systemic lupus erythematosus.","evidence":"Established"},{"condition":"Discoid lupus erythematosus","description":"This medicine is used to treat chronic skin lesions of discoid lupus erythematosus when topical therapy is not enough.","evidence":"Established"}]
Off-label uses: [{"condition":"Porphyria cutanea tarda","description":"This medicine has been used off-label in some patients with porphyria cutanea tarda to reduce skin blistering and liver iron overload, but it requires specialist supervision.","evidence":"Limited"},{"condition":"Sarcoidosis-related skin or joint symptoms","description":"This medicine has been tried off-label for selected sarcoidosis symptoms, but evidence is limited and it is not a standard first-line treatment.","evidence":"Limited"}]
Primary treatment for: Malaria
Also treats: Rheumatoid arthritis, Systemic lupus erythematosus, Discoid lupus erythematosus
📋 Drug Information
| Generic Name(s) | Chloroquine (50mg) |
| Brand Name | nivaquine p 50mg suspension |
| Manufacturer | Abbott |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | OPHTHAL |
| Action Class | Antimalarial- Aminoquinolines |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C in a dry place. Keep it in the original container with the cap tightly closed. Protect it from direct sunlight and moisture. Do not freeze the syrup. Keep all medicines out of the reach of children and pets. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture when stored as directed. Always check the expiry date on the pack and do not use the medicine after that date. Once opened, follow the manufacturer's instructions for use within the recommended period. |
| WHO Guideline | The World Health Organization recommends chloroquine only for malaria caused by chloroquine-sensitive Plasmodium species and no longer recommends it for Plasmodium falciparum malaria in most endemic areas because of widespread resistance. National treatment guidelines should always be followed. |
| ICMR Guideline | The Indian Council of Medical Research and national malaria control guidelines recommend chloroquine for Plasmodium vivax malaria and for Plasmodium falciparum malaria only in areas where the parasite is known to be chloroquine-sensitive. Guidelines should be checked for the latest recommendations because resistance patterns change over time. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by entering the acidic digestive vacuole of susceptible malaria parasites, where it becomes protonated and trapped. Inside the vacuole, chloroquine interferes with the parasite's ability to convert toxic heme into harmless hemozoin crystals. The buildup of free heme damages the parasite membrane and kills the parasite during its red blood cell stage. In autoimmune conditions, this medicine raises the pH inside lysosomes and other acidic compartments, which reduces antigen processing and presentation, dampens inflammatory signaling, and stabilizes immune cell activity. These effects help reduce joint inflammation and skin lesions in rheumatoid arthritis and lupus erythematosus.
Mechanism Steps
💡 How to Take nivaquine p 50mg suspension
Strength: This medicine is supplied as an oral syrup containing chloroquine 50 mg per measured dose. It is an immediate-release liquid formulation intended for oral use.
Dosage Information
| Adult Dosage | The adult dose of this medicine depends on the condition being treated, the sensitivity of the malaria parasite, and the patient's kidney and liver function. For malaria treatment, a clinician may prescribe an initial loading dose followed by additional doses over the next few days. For malaria prevention, the dose is usually taken once weekly starting before travel and continuing after leaving the malaria area. For autoimmune conditions, the dose is usually lower and taken once daily or every other day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Never change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing of this medicine is not established from available information for all indications. When it is used in children, the dose must be calculated by a pediatrician based on body weight and the specific condition being treated. Do not give this medicine to a child without a doctor's prescription and exact dosing instructions. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially eye problems, heart rhythm changes, muscle weakness, and low blood sugar. Kidney function often declines with age, so the dose may need to be adjusted. Elderly patients should have regular eye examinations, heart monitoring when indicated, and blood tests as advised by their doctor. |
| Renal Impairment | This medicine is partly cleared by the kidneys, so patients with kidney impairment may need a lower dose or longer dosing intervals. The exact adjustment depends on the degree of kidney impairment and the indication being treated. Kidney function should be checked before and during treatment, and the dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Patients with liver impairment may clear this medicine more slowly and may be at higher risk of side effects. The dose may need to be reduced or the medicine avoided in severe liver disease. Liver function should be monitored, and the dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of this medicine depends on the indication, the patient's weight, kidney function, and the treating doctor's judgment. There is no single fixed maximum that applies to all situations. Never exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nivaquine p 50mg suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | |
| Mefloquine | Major | |
| Insulin | Major | |
| Digoxin | Major | |
| Gold salts | Major | |
| Cimetidine | Moderate | |
| Rifampicin | Moderate | |
| Antacids | Moderate | |
| Methotrexate | Moderate | |
| Kaolin-pectin | Moderate |
🚨 Major Interactions
- Amiodarone, sotalol, dofetilide, or other QT-prolonging drugs
- Mefloquine
- Insulin and oral hypoglycemic agents
- Gold salts and penicillamine
- Digoxin
⚡ Moderate Interactions
- Cimetidine
- Rifampicin
- Antacids containing magnesium or aluminum
- Kaolin and pectin antidiarrheal products
- Methotrexate
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can worsen stomach irritation, increase the risk of liver problems, and may add to dizziness or drowsiness. It can also make it harder to recognize side effects such as low blood sugar or heart rhythm changes.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to chloroquine or other 4-aminoquinoline medicines.","Pre-existing retinopathy or visual field changes related to chloroquine or similar medicines.","Severe liver impairment unless a specialist supervises treatment.","Severe kidney impairment unless a specialist supervises treatment.","Heart block, long QT syndrome, or other significant cardiac conduction disorders.","Use for malaria caused by chloroquine-resistant Plasmodium falciparum.","Concurrent use with medicines that significantly prolong the QT interval, unless supervised by a specialist."]
⚠️ Warnings & Precautions
["This medicine can cause irreversible eye damage with long-term use, so regular eye examinations are essential.","This medicine can cause dangerous heart rhythm changes, especially in patients with heart disease or electrolyte imbalance.","This medicine can cause severe low blood sugar, particularly in patients with diabetes or those taking insulin.","This medicine can worsen psoriasis and porphyria, so tell your doctor if you have these conditions.","This medicine can cause muscle weakness and nerve damage with prolonged use.","This medicine can cause blood disorders, so report unusual bruising, bleeding, or fever.","This medicine should not be used to treat fever or suspected malaria without medical confirmation.","Children are more sensitive to the toxic effects of this medicine, so dosing must be carefully supervised by a pediatrician.","This medicine can cause drowsiness or blurred vision, so avoid driving or operating machinery until you know how it affects you.","Do not share this medicine with anyone else, even if they have similar symptoms."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding in many situations, but the decision should be made by a doctor who knows the mother's condition and the baby's health. Monitor the baby for poor feeding, irritability, or unusual sleepiness and report any concerns to a pediatrician.
💊 Overdose Management
Overdose of this medicine is a medical emergency and can be fatal. Symptoms may include severe headache, drowsiness, blurred vision, nausea, vomiting, low blood pressure, irregular heartbeat, seizures, and cardiac arrest. If an overdose is suspected, call emergency services immediately and go to the nearest hospital. Do not try to induce vomiting unless instructed by a medical professional. Treatment in hospital may include activated charcoal if the patient is seen early, intravenous fluids, medications to support blood pressure and heart rhythm, and close monitoring in an intensive care unit.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember if less than half of the dosing interval has passed. If more than half of the dosing interval has passed, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist for advice.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor and never adjust the dose on your own. Measure the syrup with the dosing cup or syringe supplied with the product so that each dose is accurate. Take this medicine with food or a glass of milk if it upsets your stomach. Keep all scheduled follow-up appointments, especially eye examinations if you are using this medicine for a long time. Tell your doctor about all other medicines, supplements, and herbal products you take, because chloroquine can interact with several drugs. Avoid alcohol while taking this medicine. Do not use this medicine to self-treat fever or suspected malaria without medical confirmation. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before using this medicine. Store this medicine out of the reach of children and never share it with anyone else.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience side effects such as dizziness, blurred vision, muscle weakness, heart rhythm changes, and low blood sugar. Kidney function often declines with age, so the dose may need adjustment. Regular eye examinations, heart monitoring, and blood tests are especially important in this age group.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, talk to your doctor before starting or continuing this medicine. Chloroquine can cross the placenta, and the decision to use it during pregnancy should be made by a specialist who can weigh the benefits and risks for both mother and baby. Do not stop or change the medicine on your own.
🏥 Post-Surgery Considerations
Tell your surgeon and anesthesiologist if you are taking this medicine before any surgery. It can affect heart rhythm and blood sugar, which are important during and after surgery. Your doctor may recommend monitoring or temporary adjustments around the time of surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It can cause dry mouth, dizziness, or changes in blood sugar, and it may interact with medicines used during dental treatment. Good oral hygiene is important, and regular dental check-ups are advised.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness, blurred vision, and muscle weakness. Avoid driving, cycling, or operating heavy machinery until you know how it affects you. If you experience muscle weakness or balance problems, stop strenuous exercise and consult your doctor. Low-impact activities such as walking or swimming are generally safer during treatment.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, blurred vision, or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. If your work involves heavy machinery or driving, discuss temporary adjustments with your employer and doctor. Most people can continue their usual daily activities with care.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. For malaria treatment, the full course must be completed even if you feel better, to prevent relapse and resistance. For autoimmune conditions, stopping suddenly can cause a flare. Your doctor will decide when and how to stop based on your condition, response, and monitoring results. If you experience serious side effects such as vision changes, heart rhythm problems, or severe allergic reactions, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to accumulation in the retina and cause irreversible vision loss, so regular eye examinations are essential. It can also cause muscle weakness, nerve damage, blood disorders, and heart rhythm changes. Patients on long-term therapy should have periodic blood tests, eye checks, and heart monitoring as advised by their doctor. The dose and duration should be reviewed regularly to ensure the benefits continue to outweigh the risks.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Using insecticide-treated nets, repellents, and protective clothing reduces the risk of malaria and complements medicine.
Evidence: Well-establishedA related medicine that is often preferred for long-term autoimmune therapy because of a lower risk of eye toxicity.
Evidence: Well-establishedThe preferred treatment for Plasmodium falciparum malaria, including chloroquine-resistant strains.
Evidence: Well-establishedCan complement medicine in rheumatoid arthritis and lupus to improve function and reduce pain.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There is no known interaction between this medicine and routine vaccines. However, if you are unwell with fever or malaria, it is better to postpone vaccination until you have recovered. Discuss the timing of any vaccine with your doctor.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not freeze the syrup.
✅ DO
Keep the bottle tightly closed in its original carton.
❌ DON'T
Do not transfer the syrup to another container.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom or near a sink.
✅ DO
Keep out of the reach of children.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When travelling with this medicine, carry it in its original labelled container along with a copy of your prescription. If you are using it for malaria prevention, start it before travel as advised by your doctor and continue after leaving the malaria area. Keep the syrup in a cool, dry place and protect it from extreme heat. If you cross time zones, ask your doctor how to adjust the dosing schedule. Declare the medicine at customs if required and never pack it in checked luggage where it may be exposed to extreme temperatures.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts reducing fever and parasite levels within 24 to 48 hours, but the full course must be completed as prescribed. Follow-up testing may be needed to confirm cure.
A: Yes. Taking this medicine with food or milk can reduce nausea and stomach discomfort.
A: Long-term use can cause retinal damage and vision loss. Regular eye examinations are essential, especially if you take this medicine for more than a few weeks.
A: Only if a qualified clinician decides the benefit clearly outweighs the risk. Do not self-medicate during pregnancy.
A: If less than half the dosing interval has passed, take the missed dose as soon as you remember. If more than half has passed, skip it and continue your regular schedule. Do not double dose.
A: It is best to avoid alcohol because it can worsen stomach irritation, dizziness, and liver-related risks.
A: Yes. It can interact with heart medicines, diabetes medicines, antacids, and several other drugs. Always tell your doctor about all medicines you take.
A: Children may be more sensitive to its effects. It should only be given under pediatric supervision with exact weight-based dosing.
🤔 Common Patient Concerns
🔄 Substitutes for nivaquine p 50mg suspension
View AllAlternative brands with exact same active ingredient:
-
amoquin 50mg syrupAmwell Pharmaceuticals Pvt Ltd ₹11.15 33.6% CHEAPER
-
jagquin 50mg syrupJagsonpal Pharmaceuticals Ltd ₹12.41 26.1% CHEAPER
-
Sequin 50mg SuspensionManeesh Pharmaceuticals Ltd ₹14.63 12.9% CHEAPER
-
malarbin 50mg suspensionAcron Pharmaceuticals ₹14.88 11.4% CHEAPER
-
quinowin suspensionTaurus Laboratories Pvt Ltd ₹14.93 11.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any type of malaria.
Fact: This medicine only works against malaria parasites that are sensitive to chloroquine. It is not effective against chloroquine-resistant malaria, especially resistant Plasmodium falciparum. - Myth: This medicine is safe to take for a long time without eye checks.
Fact: Long-term use of this medicine can damage the retina and cause permanent vision loss. Regular eye examinations are essential. - Myth: This medicine can be taken without a prescription for fever.
Fact: This medicine is a prescription medicine and should never be used to self-treat fever or suspected malaria without medical confirmation. - Myth: This medicine is safe to combine with any other medicine.
Fact: This medicine can interact with several drugs, including heart medicines, diabetes medicines, and antacids. Always tell your doctor about all medicines you take. - Myth: This medicine works immediately after the first dose.
Fact: This medicine starts reducing fever and parasites within one to two days, but full treatment and recovery take longer.
🔄 Alternative Options
Generic Alternatives
- Chloroquine syrup
- Chloroquine phosphate syrup
Brand Alternatives
- Jagquin 50mg Syrup