Necflo Oral Suspension - Ofloxacin (50mg/5ml) medicine

Albaxo Oral Suspension: Complete Medicine Guide

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🏭 Nectar Biopharma Pvt Limited 📦 bottle of 30 ml Oral Suspension 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Ofloxacin is not recommended for use during pregnancy unless the potential benefit justifies the potential risk to the fetus. It is classified as FDA Pregnancy Category C. Consult your doctor if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Irregular heartbeat or palpitations
  • Sudden joint pain or swelling

If experiencing severe symptoms, call emergency services immediately.

What is Necflo Oral Suspension used for?

This medicine is an antibiotic containing ofloxacin, used to treat various bacterial infections. It works by stopping bacteria from multiplying. Take it exactly as prescribed, and complete the full course.

  • Generic Name: Ofloxacin (50mg/5ml)
  • Manufacturer: Nectar Biopharma Pvt Limited
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Necflo Oral Suspension के बारे में (Hindi Summary)

उपयोग: यह दवा ओफ्लोक्सासिन नामक एंटीबायोटिक है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण और कुछ यौन संचारित संक्रमणों के लिए प्रभावी है। यह दवा बैक्टीरिया के डीएनए को नष्ट करके उन्हें मरने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, सिरदर्द, चक्कर आना और पेट दर्द शामिल हैं। गंभीर दुष्प्रभावों में टेंडन टूटना, तंत्रिका क्षति, दौरे और एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। पर्याप्त पानी पिएं। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ इस दवा को न लें। धूप से बचें और सनस्क्रीन का उपयोग करें। यदि आपको चक्कर आते हैं तो वाहन न चलाएं।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 Necflo Oral Suspension Uses & Benefits

[{"condition":"Urinary tract infections","description":"This medicine is effective against many bacteria that cause urinary tract infections, including complicated and uncomplicated cases.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"It is used to treat bacterial bronchitis and pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"This medicine can be prescribed for bacterial skin infections such as cellulitis and abscesses.","evidence":"Well-established"},{"condition":"Sexually transmitted infections","description":"It is used in the treatment of gonorrhea and chlamydia, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Prostatitis","description":"This medicine is effective in treating bacterial prostatitis due to its good penetration into prostate tissue.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes prescribed off-label for severe traveler's diarrhea caused by susceptible bacteria.","evidence":"Limited"},{"condition":"Epididymitis","description":"May be used off-label for epididymitis, often in combination with other antibiotics.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Sexually transmitted infections, Prostatitis

📋 Drug Information

Generic Name(s)Ofloxacin (50mg/5ml)
Brand NameNecflo Oral Suspension
ManufacturerNectar Biopharma Pvt Limited
Packaging / Formbottle of 30 ml Oral Suspension (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C). Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a full glass of water to ensure proper absorption and prevent crystal formation in urine.
2
Avoid taking antacids, iron, or zinc supplements within 2 hours of this medicine, as they can reduce its effectiveness.
3
Complete the full course of antibiotics as prescribed, even if you start feeling better after a few days.
4
Avoid excessive sun exposure and use sunscreen, as this medicine can make your skin more sensitive to sunlight.
5
Do not drive or operate heavy machinery if you experience dizziness or confusion.
6
Inform your doctor if you have kidney problems, liver problems, diabetes, or a history of tendon disorders.
7
Report any unusual symptoms like tendon pain, numbness, or tingling to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning during urination
This medicine is commonly prescribed for urinary tract infections.
Likely Use
✅
Fever with cough
May be used for respiratory tract infections.
Likely Use
✅
Skin redness and swelling
Can be used for bacterial skin infections.
Likely Use
❌
Runny nose
This medicine is not effective for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOfloxacin is rapidly and well absorbed from the gastrointestinal tract after oral administration. The oral suspension is absorbed similarly to tablets, with a bioavailability of approximately 95-100%.
DistributionOfloxacin distributes widely throughout the body, including into the lungs, kidneys, prostate, and other tissues. It also penetrates into cerebrospinal fluid to some extent.
Protein BindingApproximately 20-30% of ofloxacin is bound to plasma proteins.
MetabolismOfloxacin undergoes limited metabolism in the liver, with only a small fraction being metabolized to inactive metabolites.
Half-LifeThe elimination half-life of ofloxacin is approximately 4-5 hours in patients with normal renal function.
ExcretionOfloxacin is primarily excreted unchanged in the urine, with about 70-80% of the dose recovered in urine within 24 hours. A small amount is excreted in feces.
BioavailabilityThe oral bioavailability of ofloxacin is approximately 95-100%.
Onset of ActionThe onset of action is typically within 1-2 hours after oral administration, but clinical improvement may take 24-48 hours.
Peak Plasma TimePeak plasma concentrations are reached within 1-2 hours after oral administration.
Duration of ActionThe duration of action is approximately 12-24 hours, allowing for once or twice daily dosing.

How It Works

This medicine works by inhibiting two essential bacterial enzymes: DNA gyrase and topoisomerase IV. These enzymes are responsible for maintaining the supercoiled structure of bacterial DNA and for separating replicated DNA strands during cell division. By blocking these enzymes, this medicine prevents bacterial DNA replication and transcription, leading to bacterial cell death. This action is bactericidal, meaning it kills the bacteria rather than just stopping their growth.

Mechanism Steps

1
Entry into bacterial cell: This medicine penetrates the bacterial cell wall and enters the cytoplasm.
2
Inhibition of DNA gyrase: It binds to the DNA gyrase enzyme, preventing it from relieving supercoils in DNA during replication.
3
Inhibition of topoisomerase IV: It also binds to topoisomerase IV, which is involved in separating daughter DNA strands after replication.
4
Blockage of DNA replication: The inhibition of these enzymes leads to the arrest of DNA replication and transcription.
5
Bacterial cell death: The inability to replicate DNA results in bacterial cell death, effectively clearing the infection.

💡 How to Take Necflo Oral Suspension

Strength: Oral suspension, 50mg/5ml.

1Shake the bottle well before each use to ensure the medicine is evenly mixed.
2Measure the dose accurately using the measuring cup or syringe provided.
3Take this medicine with a full glass of water.
4You may take it with or without food, but taking it with food may reduce stomach upset.
5Do not take antacids, iron, or zinc supplements within 2 hours of this medicine.
6Complete the full course as prescribed, even if you feel better after a few days.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 200-400 mg orally every 12 hours, depending on the type and severity of the infection. For uncomplicated urinary tract infections, a single 200 mg dose may be sufficient. For other infections, treatment typically lasts 7-14 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture and CNS effects.
Renal ImpairmentIn patients with renal impairment (creatinine clearance <50 mL/min), the dose should be adjusted. For creatinine clearance 20-50 mL/min, the usual dose is 200-400 mg every 24 hours. For creatinine clearance <20 mL/min, the dose is 200 mg every 24 hours. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is required for hepatic impairment, but use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 800 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Dairy products
Separate by 2 hours
Calcium can reduce absorption.
Fortified cereals
Separate by 2 hours
Iron and zinc can reduce absorption.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Necflo Oral Suspension

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or bloody, contact your doctor immediately.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe, consult your doctor.

🚨 Serious Side Effects

Tendon rupture (Rare (<0.1%))
Seek immediate medical attention if you experience sudden pain, swelling, or inability to move a joint.
Peripheral neuropathy (Rare (<0.1%))
Report symptoms like numbness, tingling, or burning in hands or feet to your doctor immediately.
Central nervous system effects (seizures, confusion) (Rare (<0.1%))
Seek immediate medical attention if you experience seizures, confusion, or hallucinations.
Severe allergic reactions (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Heart rhythm disturbances (QT prolongation) (Rare (<0.1%))
Seek medical attention if you experience palpitations, fainting, or irregular heartbeat.

⚠️ Rare Side Effects

Liver damage (hepatotoxicity)
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Blood sugar disturbances (hypoglycemia or hyperglycemia)
Monitor blood sugar closely if diabetic. Report symptoms like excessive hunger, sweating, or confusion.
Photosensitivity
Avoid sun exposure and use sunscreen. Report severe sunburn or rash.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antacids Major
Warfarin Major
Theophylline Major
NSAIDs Major
Corticosteroids Major
Probenecid Moderate
Cimetidine Moderate
Oral hypoglycemics Moderate
Phenytoin Moderate
Cyclosporine Minor

🚨 Major Interactions

  • Antacids, sucralfate, iron, zinc
  • Warfarin
  • Theophylline
  • NSAIDs
  • Corticosteroids

⚡ Moderate Interactions

  • Probenecid
  • Cimetidine
  • Oral hypoglycemics
  • Phenytoin

🍷 Alcohol Interaction

Alcohol may increase the risk of central nervous system side effects such as dizziness, drowsiness, and confusion. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ofloxacin or other fluoroquinolones","History of tendon disorders related to fluoroquinolone use","Myasthenia gravis (may worsen muscle weakness)","Children and adolescents (except for specific serious infections under specialist care)","Pregnancy and lactation (unless benefits outweigh risks)"]

⚠️ Warnings & Precautions

["Tendon rupture, including Achilles tendon, can occur; risk is increased in elderly, patients on corticosteroids, and organ transplant recipients.","Peripheral neuropathy may occur and can be irreversible.","Central nervous system effects including seizures, confusion, and hallucinations have been reported.","May exacerbate myasthenia gravis.","Avoid excessive sun exposure due to photosensitivity.","May cause blood sugar disturbances; monitor closely in diabetic patients.","Not recommended for use in children except for specific indications.","Use with caution in patients with renal impairment; dose adjustment required."]

🤱 Lactation Safety

Ofloxacin is excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, dizziness, and seizures. Treatment is symptomatic and supportive. Adequate hydration should be maintained to prevent crystalluria. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to antibiotic resistance. Take this medicine with plenty of water to prevent crystal formation in urine. Avoid taking antacids, iron, or zinc supplements within 2 hours before or after taking this medicine, as they can reduce its absorption. Avoid excessive sunlight and use sunscreen, as this medicine can make your skin more sensitive to sunlight. Do not drive or operate heavy machinery if you experience dizziness or confusion. Inform your doctor if you have kidney problems, liver problems, diabetes, or a history of tendon disorders. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at increased risk of tendon rupture, peripheral neuropathy, and central nervous system effects. Dose adjustment may be needed based on renal function. Use with caution.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Ofloxacin is not recommended during pregnancy unless clearly needed.

🏥 Post-Surgery Considerations

If you are undergoing surgery, inform your surgeon that you are taking this medicine. It may need to be stopped before surgery due to the risk of tendon rupture and bleeding.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with other medications used during dental work.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of water throughout the day.
🥗
Avoid excessive sun exposure and use sunscreen to prevent photosensitivity reactions.
😴
Maintain good hygiene to prevent the spread of infection.
💧
Get adequate rest to help your body fight the infection.
🧘
Eat a balanced diet to support your immune system.
🌞
Avoid alcohol while taking this medicine.

🏋️ Exercise Considerations

Avoid strenuous exercise or activities that could cause tendon strain while taking this medicine, as it increases the risk of tendon rupture. If you experience joint pain or swelling, stop exercising and consult your doctor.

🥗 Diet Recommendations

Drink plenty of water to stay hydrated.
Include probiotic-rich foods like yogurt to maintain gut health.
Avoid taking dairy products or fortified cereals within 2 hours of this medicine.
Limit caffeine intake as it may increase jitteriness.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, confusion, or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is important to take it as prescribed and not skip doses, even if you feel better.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects, contact your doctor immediately for guidance.

📅 Long-Term Use Effects

Long-term use of this medicine can lead to antibiotic resistance and may increase the risk of tendon rupture, peripheral neuropathy, and central nervous system effects. It should only be used for the prescribed duration. Regular monitoring of kidney and liver function may be required if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Increased fluid intake

For urinary tract infections, drinking plenty of water can help flush out bacteria.

Evidence: Well-established
Probiotics

May help prevent antibiotic-associated diarrhea.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are scheduled for a vaccination, inform your doctor that you are taking this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Check local customs regulations regarding prescription medications before traveling.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a urinary tract infection. She took it as directed with plenty of water and completed the 7-day course. Her symptoms improved within 3 days, and she felt completely better by the end of the course. She emphasized the importance of not skipping doses.
💡 Lesson: Completing the full course of antibiotics is crucial to fully eliminate the infection and prevent resistance.
👤 A 60-year-old man with a respiratory tract infection
He was prescribed this medicine for bronchitis. He experienced mild nausea initially, but it subsided when he took the medicine with food. He was advised to avoid antacids within 2 hours of the dose. His cough and fever resolved within a week.
💡 Lesson: Taking this medicine with food can reduce stomach upset, and avoiding antacids ensures proper absorption.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.

Q: Can I take it with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe during pregnancy?

A: Ofloxacin is not recommended during pregnancy unless the potential benefit justifies the risk. Consult your doctor.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may increase the risk of central nervous system side effects like dizziness and drowsiness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Necflo Oral Suspension

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the flu.
    Fact: This medicine is an antibiotic and only works against bacterial infections. It is ineffective against viruses.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent recurrence and resistance.
  • Myth: This medicine is safe for everyone.
    Fact: It is not recommended for children, pregnant women, or those with certain medical conditions. Consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Ofloxacin oral suspension

Brand Alternatives

  • Albaxo oral suspension

📊 Comparison with Similar Medicines

[{"medicine":"Ofloxacin","class":"Fluoroquinolone","route":"Oral","common_uses":"UTI, respiratory, skin infections"},{"medicine":"Ciprofloxacin","class":"Fluoroquinolone","route":"Oral","common_uses":"UTI, GI infections, respiratory"},{"medicine":"Levofloxacin","class":"Fluoroquinolone","route":"Oral","common_uses":"Respiratory, UTI, skin"}]

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