Nasoshine Af Nasal Spray: Complete Guide To Uses, Dosage, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe or persistent nosebleeds
- Sudden swelling of face, lips, or throat
- Difficulty breathing or wheezing
- Severe headache with vision changes
- Signs of infection such as fever and facial pain
- Unusual tiredness or weakness
- Yellowing of eyes or skin
If experiencing severe symptoms, call emergency services immediately.
What is nasoshine af nasal spray used for?
This medicine is a combination nasal spray used to treat allergic rhinitis. It contains fluticasone furoate (a steroid) and azelastine (an antihistamine) to reduce inflammation and allergy symptoms. It is sprayed into each nostril once or twice daily as prescribed.
- Generic Name: Fluticasone Furoate (50mcg) + Azelastine (140mcg)
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nasoshine af nasal spray के बारे में (Hindi Summary)
उपयोग: यह दवा एलर्जिक राइनाइटिस (नाक की एलर्जी) के इलाज के लिए एक नेज़ल स्प्रे है। इसमें फ्लूटिकासोन फ्यूरोएट और एज़ेलास्टीन दो सक्रिय तत्व हैं। यह नाक की सूजन, छींक, खुजली, बहती नाक और नाक बंद होने जैसे लक्षणों को कम करने में मदद करती है। यह मौसमी और साल भर रहने वाली एलर्जी दोनों के लिए प्रभावी है। यह दवा 6 साल से बड़े बच्चों और वयस्कों के लिए है। इसे डॉक्टर के निर्देशानुसार ही इस्तेमाल करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कड़वा स्वाद, नाक से खून आना, सिरदर्द और नाक में जलन शामिल हैं। कुछ लोगों को नींद आना या थकान महसूस हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन तेज नाक से खून आना, नाक में छेद होना, या एलर्जी प्रतिक्रिया हो सकती है। अगर आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का उपयोग करने से पहले बोतल को हल्का हिलाएं। आंखों या मुंह में स्प्रे न करें। अगर आपको नाक में संक्रमण या हाल ही में नाक की चोट लगी है तो इसका इस्तेमाल न करें। निर्धारित मात्रा से ज्यादा न लें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। इसे कमरे के तापमान पर स्टोर करें।
💊 nasoshine af nasal spray Uses & Benefits
[{"condition":"Seasonal allergic rhinitis","description":"Relieves nasal congestion, sneezing, itching, and runny nose caused by seasonal allergens like pollen.","evidence":"Well-established"},{"condition":"Perennial allergic rhinitis","description":"Provides long-term relief from year-round allergy symptoms due to dust mites, pet dander, or mold.","evidence":"Well-established"},{"condition":"Moderate to severe allergic rhinitis","description":"Used when monotherapy with an antihistamine or corticosteroid is insufficient.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Non-allergic rhinitis","description":"May be used off-label for vasomotor rhinitis with some benefit.","evidence":"Limited"},{"condition":"Nasal polyposis","description":"Sometimes prescribed off-label to reduce nasal polyp size and symptoms.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Seasonal allergic rhinitis, Perennial allergic rhinitis
📋 Drug Information
| Generic Name(s) | Fluticasone Furoate (50mcg) + Azelastine (140mcg) |
| Brand Name | nasoshine af nasal spray |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Intranasal |
| Storage | Store at room temperature (15-30°C). Protect from light. Do not freeze. Keep the bottle upright. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Fluticasone furoate is a synthetic corticosteroid that binds to glucocorticoid receptors in the nasal mucosa, reducing the release of inflammatory mediators and inhibiting the recruitment of inflammatory cells. Azelastine is a second-generation antihistamine that selectively blocks H1 histamine receptors, preventing histamine-induced sneezing, itching, and vasodilation. The combination provides both anti-inflammatory and antihistaminic effects, offering broader symptom relief than either agent alone.
Mechanism Steps
💡 How to Take nasoshine af nasal spray
Strength: Nasal spray containing fluticasone furoate 50 mcg and azelastine 140 mcg per spray.
Dosage Information
| Adult Dosage | The usual adult dose is one spray in each nostril once daily. For some patients, one spray in each nostril twice daily may be prescribed. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed two sprays in each nostril per day. |
| Pediatric Dosage | For children 6 years and older, the usual dose is one spray in each nostril once daily. Pediatric dosing is not established for children under 6 years. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but use with caution due to potential for increased sensitivity to side effects. |
| Renal Impairment | No dose adjustment is required for mild to moderate renal impairment. Use with caution in severe renal impairment. |
| Hepatic Impairment | No dose adjustment is required for mild to moderate hepatic impairment. Use with caution in severe hepatic impairment. |
| Maximum Daily Dose | Two sprays in each nostril per day (total daily dose: fluticasone furoate 200 mcg, azelastine 560 mcg). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nasoshine af nasal spray
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Ritonavir | Major | |
| Diazepam | Moderate | |
| Alcohol | Moderate | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- Alcohol
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids)
- Ritonavir
🍷 Alcohol Interaction
Alcohol may increase drowsiness and dizziness caused by azelastine. It is advisable to avoid alcohol while using this medicine, especially when driving or operating machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to fluticasone furoate, azelastine, or any component of the formulation","Untreated nasal infections (e.g., herpes simplex)","Recent nasal surgery or trauma until healing occurs","Children under 6 years of age"]
⚠️ Warnings & Precautions
["Do not use for more than 3 months without medical review.","Avoid contact with eyes. If contact occurs, rinse thoroughly with water.","Use with caution in patients with active or latent tuberculosis, or ocular herpes simplex.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use in children under 6 years without medical advice.","If symptoms do not improve after 2 weeks, consult your doctor."]
🤱 Lactation Safety
It is not known whether this medicine passes into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with intranasal fluticasone furoate and azelastine is unlikely to cause serious acute effects due to low systemic absorption. If accidental ingestion occurs, seek medical attention. Symptoms of overdose may include drowsiness, dizziness, and nasal irritation. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before using this medicine, shake the bottle gently and prime it if it is new or has not been used for more than 7 days. Do not spray into the eyes or mouth. Avoid using this medicine if you have a nasal infection or recent nasal injury. Do not exceed the prescribed dose. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before use. Keep out of reach of children. Do not share your nasal spray with others. Store at room temperature and protect from light.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness. Use with caution and monitor for any adverse effects.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medicine during pregnancy is not fully established.
🏥 Post-Surgery Considerations
Avoid using this medicine immediately after nasal surgery until healing is complete, as it may interfere with healing and increase the risk of infection.
🦷 Dental Procedures
No specific precautions are required for dental procedures. However, inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness in some people. Avoid strenuous exercise or operating machinery until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is advisable to avoid these activities until you know how the medicine affects you. Otherwise, it should not significantly impact your daily work life.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or no improvement after 2 weeks, consult your doctor who may adjust or change the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of nasal septal perforation, glaucoma, and cataracts. Regular monitoring by an eye doctor and ENT specialist is recommended if used for more than 3 months. Growth should be monitored in children on prolonged therapy.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing exposure to allergens can help manage symptoms.
Evidence: Well-establishedCan help clear nasal passages and reduce symptoms.
Evidence: ModerateAllergy shots or sublingual tablets can provide long-term relief.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, if you are on long-term high-dose corticosteroids, consult your doctor before receiving live vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue your regular dosing schedule. Check customs regulations for carrying prescription nasal sprays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Azelastine starts working within 15-30 minutes, while fluticasone furoate takes several days for full effect.
A: No, this medicine is for allergic rhinitis, not for viral colds.
A: It is approved for children 6 years and older. Consult a pediatrician for younger children.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This nasal spray is addictive.
Fact: This medicine is not addictive. It does not contain any habit-forming substances. - Myth: It can be used for the common cold.
Fact: This medicine is for allergic rhinitis, not for viral colds. It may not help with cold symptoms. - Myth: It works immediately.
Fact: Azelastine works within 30 minutes, but fluticasone takes several days for full effect.