Naso CZ Tablet - Ambroxol (NA) + Levocetirizine (NA) medicine

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🏭 Chem + Med Pharmaceuticals 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for combination; well-established for individual components.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or shortness of breath
  • Swelling of the face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Irregular or rapid heartbeat
  • Blood in sputum or vomit
  • Severe headache with visual changes
  • Yellowing of skin or eyes (jaundice)
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is Naso CZ Tablet used for?

This medicine is a combination of Ambroxol and Levocetirizine used to treat productive cough with allergic symptoms. It works by thinning mucus and blocking histamine. It is usually taken once or twice daily as prescribed.

  • Generic Name: Ambroxol (NA) + Levocetirizine (NA)
  • Manufacturer: Chem + Med Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Naso CZ Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एम्ब्रोक्सोल और लेवोसेटिरिज़ीन का संयोजन है, जिसका उपयोग बलगम वाली खांसी और एलर्जी के लक्षणों के इलाज के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है और एलर्जी से होने वाली छींक, नाक बहना, खुजली को कम करती है। यह दवा केवल डॉक्टर के परामर्श से लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, सिरदर्द और हल्का पेट दर्द शामिल हैं। कभी-कभी चक्कर आना, मतली या दिल की धड़कन बढ़ना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपनी मर्जी से मात्रा या अवधि न बढ़ाएं। दवा लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। 7 दिनों से अधिक खांसी रहने पर डॉक्टर से सलाह लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 Naso CZ Tablet Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"Helps loosen and thin mucus in the airways, making it easier to expel.","evidence":"Well-established for Ambroxol component"},{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itching, and nasal congestion due to allergies.","evidence":"Well-established for Levocetirizine component"},{"condition":"Allergic cough","description":"Reduces cough triggered by allergic reactions and postnasal drip.","evidence":"Moderate evidence for combination"}]

Off-label uses: [{"condition":"Chronic bronchitis","description":"Sometimes used to ease mucus clearance in chronic bronchitis, but not a primary treatment.","evidence":"Limited"},{"condition":"Sinusitis","description":"May help reduce nasal congestion and mucus in sinusitis, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Productive cough with allergic rhinitis

Also treats: Allergic bronchitis, Sinusitis with postnasal drip

📋 Drug Information

Generic Name(s)Ambroxol (NA) + Levocetirizine (NA)
Brand NameNaso CZ Tablet
ManufacturerChem + Med Pharmaceuticals
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce the risk of stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not consume alcohol while taking this medicine as it increases drowsiness.
4
Stay well hydrated to help loosen mucus and soothe your throat.
5
Do not use this medicine for more than 7 days without consulting your doctor.
6
If you have kidney or liver problems, inform your doctor before taking this medicine.
7
Report any signs of allergic reactions such as rash, itching, or swelling immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Sneezing and runny nose
This medicine helps with allergic symptoms.
Likely Use
❌
Dry cough
This medicine is not for dry cough; it may not help.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmbroxol is rapidly absorbed from the gastrointestinal tract after oral administration. Levocetirizine is also rapidly and extensively absorbed. Food does not significantly affect the absorption of either component.
DistributionAmbroxol distributes widely into body tissues, including lung tissue, and crosses the blood-brain barrier to some extent. Levocetirizine distributes into body tissues, with about 90% bound to plasma proteins.
Protein BindingAmbroxol is approximately 80-90% bound to plasma proteins. Levocetirizine is about 90% bound to plasma proteins.
MetabolismAmbroxol is metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4, to inactive metabolites. Levocetirizine undergoes minimal metabolism in humans.
Half-LifeThe elimination half-life of Ambroxol is approximately 7-12 hours. Levocetirizine has an elimination half-life of about 6-10 hours in adults with normal kidney function.
ExcretionAmbroxol and its metabolites are mainly excreted in the urine. Levocetirizine is primarily excreted unchanged in the urine.
BioavailabilityThe oral bioavailability of Ambroxol is about 70-80% due to first-pass metabolism. Levocetirizine has a high oral bioavailability of approximately 100%.
Onset of ActionAmbroxol's mucolytic effect may begin within 30 minutes to 1 hour after oral intake. Levocetirizine starts reducing allergic symptoms within 1 hour.
Peak Plasma TimeAmbroxol reaches peak plasma concentrations about 1-3 hours after oral administration. Levocetirizine peaks at about 0.9 hours.
Duration of ActionThe effects of Ambroxol last for about 6-8 hours, requiring multiple daily doses. Levocetirizine provides relief for about 24 hours, allowing once-daily dosing.

How It Works

This medicine combines two active ingredients with complementary actions. Ambroxol acts as a mucolytic and expectorant, reducing mucus viscosity and promoting its clearance from the respiratory tract. Levocetirizine is a selective peripheral H1-receptor antagonist that blocks histamine, reducing allergic symptoms such as sneezing, itching, and runny nose. Together, they address both mucus congestion and allergic components of respiratory conditions.

Mechanism Steps

1
Ambroxol: Mucolytic action: Ambroxol breaks down acidic mucopolysaccharide fibers in mucus, reducing its thickness and making it easier to cough out.
2
Ambroxol: Expectorant effect: It stimulates the serous cells of the bronchial glands to produce more fluid, which helps dilute mucus and facilitates its removal.
3
Levocetirizine: Histamine blockade: Levocetirizine selectively binds to H1 receptors on cells, preventing histamine from triggering allergic responses like sneezing, itching, and runny nose.
4
Levocetirizine: Anti-inflammatory effects: It reduces the migration of inflammatory cells such as eosinophils, decreasing swelling and irritation in the nasal passages and airways.

💡 How to Take Naso CZ Tablet

Strength: Not established from the available information.

1Take this medicine orally with a glass of water.
2It can be taken with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at the same time each day to maintain consistent levels.
5Do not exceed the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally once or twice daily, or as directed by your physician. The exact dose and duration depend on the condition being treated, your age, kidney and liver function, and response to therapy. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Dose adjustment may be necessary based on renal function. Consult your doctor for appropriate dosing.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For Levocetirizine, the dose should be reduced in moderate to severe renal impairment. Consult your doctor for specific dosing recommendations based on creatinine clearance.
Hepatic ImpairmentNo specific dose adjustment is established for mild to moderate hepatic impairment. Use with caution in severe hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is one tablet twice daily, but this must be confirmed by your doctor. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Naso CZ Tablet

✅ Common Side Effects

Drowsiness (Common (5-10%))
Avoid driving or operating machinery. Usually resolves with continued use.
Dry mouth (Common (5-10%))
Sip water frequently or chew sugar-free gum.
Fatigue (Common (5-10%))
Get adequate rest. Consult doctor if persistent.
Headache (Common (5-10%))
Take rest, stay hydrated. Consult doctor if severe.
Nausea (Uncommon (1-5%))
Take with food to reduce stomach upset.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical help if you experience rash, swelling, or difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Contact doctor immediately if you feel palpitations or dizziness.
Blood disorders (e.g., agranulocytosis) (Very rare (<0.01%))
Report unusual bruising, bleeding, or fever to your doctor.

⚠️ Rare Side Effects

Liver enzyme elevation
Regular monitoring if long-term use. Report jaundice or dark urine.
Seizures
Seek emergency care if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Alcohol Major
Benzodiazepines Major
MAOIs Major
Anticholinergics Moderate
Ritonavir Moderate
Theophylline Minor

🚨 Major Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Ritonavir

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine as it can enhance the sedative effects of Levocetirizine, leading to increased drowsiness, dizziness, and impaired coordination. This can affect your ability to drive or operate machinery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Ambroxol, Levocetirizine, or any component of the formulation","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol consumption.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with hepatic impairment.","Not recommended for children under 12 years.","Do not use for dry cough or for cough lasting more than 7 days without medical advice.","May impair ability to perform tasks requiring alertness.","Consult doctor if symptoms worsen or do not improve."]

🤱 Lactation Safety

Not established from the available information. It is not known whether Ambroxol or Levocetirizine passes into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, dizziness, nausea, and in extreme cases, seizures or cardiac arrhythmias. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Avoid consuming alcohol while taking this medicine, as it can increase drowsiness and dizziness. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for a dry cough or for a cough lasting more than 7 days without consulting a doctor. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the sedative and anticholinergic effects of this medicine. Dose adjustment may be needed based on kidney function. Regular monitoring for side effects is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy is not well established, and your doctor may recommend alternative treatments.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, consult your doctor before taking this medicine, as it may interact with anesthetics or other medications. It may also affect your ability to recover if drowsiness is a concern.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may cause dry mouth and increase the risk of dental issues. Also, the sedative effect may interact with dental anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus and soothe your throat.
🥗
Use a humidifier in your room to ease breathing.
😴
Avoid exposure to allergens like dust, pollen, and smoke.
💧
Get plenty of rest to support your immune system.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid cold drinks and ice cream if they trigger your cough.

🏋️ Exercise Considerations

This medicine may cause drowsiness or dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light exercise like walking may be fine if you feel up to it.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Avoid cold and sugary drinks that can thicken mucus.
Eat a balanced diet rich in vitamins and minerals.
Include anti-inflammatory foods like ginger, turmeric, and garlic.
Avoid processed and fried foods that may worsen congestion.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. Inform your employer if your job involves such tasks.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use of Levocetirizine may lead to tolerance or rare blood disorders. Ambroxol long-term use may rarely affect liver enzymes. Regular monitoring of liver and kidney function may be advised if used for extended periods. Consult your doctor for periodic evaluation.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion naturally.

Evidence: Well-established
Saline nasal irrigation

Can reduce nasal congestion and allergy symptoms.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can decrease reliance on medication.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage to avoid loss. Check customs regulations for carrying prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies and productive cough
She was prescribed this medicine for her cough and allergic rhinitis. After taking it for 3 days, she noticed significant reduction in sneezing and her cough became more productive, making it easier to expel mucus. She experienced mild drowsiness initially, which subsided after a few days. She was advised to take it with food to avoid stomach upset.
💡 Lesson: Taking this medicine with food and avoiding driving until you know its effects can improve tolerability and safety.
👤 A 50-year-old man with chronic bronchitis
He used this medicine as part of his treatment for chronic bronchitis with allergic component. He found that his chest congestion improved and he could breathe easier. However, he had to stop it after 5 days as he developed mild nausea. His doctor adjusted the timing to after meals, which helped.
💡 Lesson: If side effects occur, consult your doctor; adjusting the timing with food can help manage them.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling relief from allergic symptoms within 1 hour, and mucolytic effects may begin within 30 minutes to 1 hour. However, full benefits may take a few days.

Q: Can I take it with other cold medicines?

A: Consult your doctor before combining with other cold medicines, as they may contain similar ingredients and increase the risk of side effects.

Q: Is it safe during pregnancy?

A: The safety of this medicine during pregnancy is not well established. Consult your doctor before taking it if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Naso CZ Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: It is only effective for productive cough with mucus and allergic components. It is not for dry cough or infections requiring antibiotics.
  • Myth: It is safe to take without a prescription.
    Fact: It is a prescription medicine and should only be taken under a doctor's supervision.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Levocetirizine combination generics

Brand Alternatives

  • Somavent Max Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Ambroxol + Levocetirizine","key_difference":"Combines mucolytic and antihistamine for cough with allergy."},{"medicine":"Ambroxol + Cetirizine","key_difference":"Cetirizine is first-generation antihistamine, more sedating."},{"medicine":"Levocetirizine alone","key_difference":"Only treats allergy, no mucolytic action."}]

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