Naprosyn Sr Tablet (naproxen 750mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual weight gain or swelling in ankles
If experiencing severe symptoms, call emergency services immediately.
What is naprosyn sr tablet used for?
This medicine is a sustained-release NSAID containing naproxen 750 mg. It is used to relieve pain and inflammation in conditions like arthritis, gout, and musculoskeletal injuries. It works by blocking COX enzymes. Take it with food to reduce stomach upset. Do not crush or chew the tablet.
- Generic Name: Naproxen (750mg)
- Manufacturer: RPG Life Sciences Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 naprosyn sr tablet के बारे में (Hindi Summary)
उपयोग: यह दवा नैप्रोक्सन 750 मिलीग्राम का सस्टेन्ड-रिलीज़ टैबलेट है, जिसका उपयोग दर्द, सूजन और जकड़न को कम करने के लिए किया जाता है। यह गठिया (ऑस्टियोआर्थराइटिस, रूमेटॉइड आर्थराइटिस), एंकिलोज़िंग स्पॉन्डिलाइटिस, गाउट के दौरे, मांसपेशियों की चोट और मासिक धर्म के दर्द में प्रभावी है। यह दवा शरीर में सूजन पैदा करने वाले प्रोस्टाग्लैंडिन नामक रसायनों को रोककर काम करती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। इसे चबाना या तोड़ना नहीं चाहिए। इसका उपयोग डॉक्टर की सलाह के अनुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में पेट में जलन, अपच, मतली, सिरदर्द, चक्कर आना और शरीर में सूजन शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, दिल का दौरा, स्ट्रोक, गुर्दे की समस्या और गंभीर एलर्जी प्रतिक्रिया शामिल हैं। यदि आपको काला मल, खून की उल्टी, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या पेशाब कम आना जैसे लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। टैबलेट को पूरा निगलें, चबाएं या तोड़ें नहीं। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब न लें, क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको पेट के अल्सर, हृदय रोग, गुर्दे की बीमारी या उच्च रक्तचाप है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। दवा को बच्चों की पहुंच से दूर ठंडी और सूखी जगह पर रखें।
💊 naprosyn sr tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain, stiffness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling in joints affected by osteoarthritis, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint inflammation, pain, and swelling in rheumatoid arthritis, though it does not halt disease progression.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate back pain and stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute gout","description":"Provides rapid relief from pain and inflammation during acute gout attacks.","evidence":"Well-established"},{"condition":"Musculoskeletal injuries","description":"Used for short-term management of pain and inflammation from strains, sprains, and other soft tissue injuries.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but evidence is limited.","evidence":"Limited"},{"condition":"Alzheimer's disease","description":"Investigated for potential neuroprotective effects, but not recommended for routine use.","evidence":"Insufficient"}]
Primary treatment for: Osteoarthritis
Also treats: Rheumatoid arthritis, Ankylosing spondylitis, Acute gout, Dysmenorrhea, Musculoskeletal injuries
📋 Drug Information
| Generic Name(s) | Naproxen (750mg) |
| Brand Name | naprosyn sr tablet |
| Manufacturer | RPG Life Sciences Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by reversibly inhibiting the cyclooxygenase enzymes COX-1 and COX-2, which are involved in the synthesis of prostaglandins from arachidonic acid. Prostaglandins are key mediators of pain, inflammation, and fever. By blocking their production, this medicine reduces pain, swelling, and stiffness. The sustained-release formulation allows for gradual absorption, providing prolonged therapeutic levels.
Mechanism Steps
💡 How to Take naprosyn sr tablet
Strength: Sustained-release tablet, 750 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 750 mg once daily or as directed by your doctor. For some conditions, a starting dose of 750 mg once daily may be followed by 375 mg to 750 mg twice daily. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. Take with food or milk to reduce stomach upset. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney impairment. Use the lowest effective dose for the shortest duration. Monitor kidney function and blood pressure regularly. |
| Renal Impairment | In patients with mild to moderate kidney impairment (eGFR 30-59 mL/min), use with caution and consider dose reduction. In severe kidney impairment (eGFR <30 mL/min), this medicine is contraindicated. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, use with caution and consider dose reduction. In severe liver impairment, this medicine is contraindicated. |
| Maximum Daily Dose | The maximum recommended daily dose is 1500 mg, but the usual maximum for sustained-release is 1500 mg per day in divided doses. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of naprosyn sr tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| ACE inhibitors | Major | |
| Lithium | Major | |
| Methotrexate | Major | |
| Diuretics | Moderate | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Aspirin
- ACE inhibitors
- Lithium
- Methotrexate
⚡ Moderate Interactions
- Diuretics
- Corticosteroids
- SSRIs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of stomach bleeding and ulcers, and may worsen liver and kidney side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to naproxen or other NSAIDs","History of asthma, urticaria, or allergic reaction after taking aspirin or other NSAIDs","Active peptic ulcer or gastrointestinal bleeding","Severe kidney impairment (eGFR
⚠️ Warnings & Precautions
["This medicine may increase the risk of serious cardiovascular events. Use with caution in patients with heart disease.","Gastrointestinal bleeding, ulceration, and perforation can occur without warning. Use the lowest effective dose for the shortest duration.","Kidney function may deteriorate, especially in dehydrated patients or those with pre-existing kidney disease.","This medicine can cause fluid retention and edema. Use with caution in patients with heart failure or hypertension.","Avoid use in patients with a history of peptic ulcer disease unless absolutely necessary and with gastroprotection.","May impair platelet function and prolong bleeding time. Use with caution before surgery.","Serious skin reactions, including exfoliative dermatitis, Stevens-Johnson syndrome, and toxic epidermal necrolysis, have been reported rarely."]
🤱 Lactation Safety
Naproxen is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but consult your doctor before use.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, drowsiness, headache, and in severe cases, gastrointestinal bleeding, kidney failure, and seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be administered if the patient presents early. Hemodialysis is not effective for removing naproxen.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the sustained-release tablet; swallow it whole with a full glass of water. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine, as it can increase the risk of stomach bleeding. Do not use this medicine for more than the recommended duration without medical advice. If you have a history of stomach ulcers, heart disease, kidney problems, or high blood pressure, inform your doctor before starting this medicine. Do not take other NSAIDs or pain relievers without consulting your doctor, as this can increase the risk of side effects. Regular monitoring of kidney function, liver function, and blood pressure may be needed during long-term therapy. If you are pregnant, planning to become pregnant, or breastfeeding, discuss with your doctor before using this medicine. Keep this medicine out of reach of children and store it in a cool, dry place.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney function and blood pressure regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are not recommended during the third trimester. Use effective contraception if appropriate.
🏥 Post-Surgery Considerations
This medicine may increase the risk of bleeding and should be used with caution after surgery. Consult your surgeon before resuming this medicine. It may also impair bone healing.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it can increase bleeding during dental procedures. You may need to stop it temporarily before surgery.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may engage in light to moderate exercise as tolerated. However, avoid high-impact activities that could exacerbate joint pain or increase the risk of bleeding. Listen to your body and rest if you experience increased pain or swelling.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also increase sensitivity to sunlight; use sunscreen when outdoors.
🛑 When to Stop This Medicine
Do not stop taking this medicine abruptly without consulting your doctor, especially if you have been on long-term therapy. Your doctor may taper the dose gradually. If you experience serious side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, cardiovascular events, and liver toxicity. Regular monitoring of kidney function, liver function, blood pressure, and complete blood count is recommended. The lowest effective dose should be used for the shortest duration possible.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve joint function.
Evidence: Well-establishedMay help reduce pain in some individuals with osteoarthritis.
Evidence: ModerateMay provide localized pain relief with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust your dosing schedule gradually to avoid missing doses. Check local customs regulations regarding prescription medications. Always carry enough supply for your entire trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 1 hour, but the full anti-inflammatory effect may take several days to weeks.
A: No, it should be taken with food or milk to reduce stomach upset.
A: Consult your doctor before combining with other NSAIDs or aspirin, as it can increase the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for naprosyn sr tablet
View AllAlternative brands with exact same active ingredient:
-
napexar 750mg tabletRPG Life Sciences Ltd ₹27.15 71.4% CHEAPER
-
naxen 750mg tablet crElder Pharmaceuticals Ltd ₹27.69 70.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe to take on an empty stomach.
Fact: This medicine should be taken with food or milk to reduce the risk of stomach upset and bleeding. - Myth: This medicine can be taken indefinitely without any monitoring.
Fact: Long-term use requires regular monitoring of kidney, liver, and cardiovascular health. - Myth: This medicine is safe to combine with other pain relievers.
Fact: Combining with other NSAIDs or aspirin can increase the risk of side effects. Consult your doctor before combining.
🔄 Alternative Options
Generic Alternatives
- Naproxen sustained-release tablet
Brand Alternatives
- Naprosyn SR
- Naprosyn
- Naproxen SR