mydrox 500mg/500mg tablet - Cefadroxil (500mg) + Probenecid (500mg) medicine

Dax LA 500 mg/500 mg Tablet: Complete Medicine Guide

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🏭 Solitaire Pharmacia Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe blistering rash or peeling skin
  • Blood in urine or stool
  • Severe abdominal pain
  • Unusual bleeding or bruising
  • Decreased urine output
  • Yellowing of eyes or skin

If experiencing severe symptoms, call emergency services immediately.

What is mydrox 500mg/500mg tablet used for?

This medicine is a combination antibiotic containing cefadroxil and probenecid. It is used to treat bacterial infections by killing bacteria and increasing the antibiotic's duration in the body.

  • Generic Name: Cefadroxil (500mg) + Probenecid (500mg)
  • Manufacturer: Solitaire Pharmacia Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 mydrox 500mg/500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सेफाड्रोक्सिल और प्रोबेनेसिड का संयोजन है, जिसका उपयोग बैक्टीरियल संक्रमण जैसे श्वसन तंत्र, मूत्र मार्ग और त्वचा के संक्रमण के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारती है और प्रोबेनेसिड शरीर में सेफाड्रोक्सिल के स्तर को बढ़ाता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, त्वचा पर चकत्ते, खून की समस्या या गुर्दे की समस्या हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और पूरा कोर्स पूरा करें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। पर्याप्त पानी पिएं। शराब से बचें। गुर्दे या लीवर की बीमारी हो तो डॉक्टर को बताएं। एलर्जी होने पर तुरंत चिकित्सा सहायता लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 mydrox 500mg/500mg tablet Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat infections of the throat, tonsils, sinuses, and lungs caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated urinary tract infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Prescribed for cellulitis, abscesses, and other skin infections caused by susceptible bacteria.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Urinary tract infections, Skin infections

📋 Drug Information

Generic Name(s)Cefadroxil (500mg) + Probenecid (500mg)
Brand Namemydrox 500mg/500mg tablet
ManufacturerSolitaire Pharmacia Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food to minimize stomach upset.
2
Complete the full course even if you feel better after a few days.
3
Drink plenty of water throughout the day to protect your kidneys.
4
Avoid alcohol while taking this medicine.
5
Inform your doctor if you have a history of kidney disease, gout, or blood disorders.
6
Do not share this medicine with others, even if they have similar symptoms.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with sore throat
This medicine may be prescribed for bacterial throat infections.
Likely Use
✅
Burning urination
This medicine is used for urinary tract infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefadroxil is well absorbed from the gastrointestinal tract after oral administration. Probenecid is also absorbed orally. Food may slightly delay absorption but does not significantly reduce the extent of absorption.
DistributionCefadroxil distributes widely into body tissues and fluids, including the respiratory tract, urinary tract, and skin. Probenecid is highly protein-bound and distributes mainly in the extracellular fluid.
Protein BindingCefadroxil is approximately 20% protein-bound. Probenecid is about 75-95% bound to plasma proteins, primarily albumin.
MetabolismCefadroxil is not significantly metabolized. Probenecid is metabolized in the liver to glucuronide conjugates and other metabolites.
Half-LifeThe elimination half-life of cefadroxil is approximately 1.5 to 2 hours, which is prolonged when given with probenecid. Probenecid has a half-life of about 6 to 12 hours.
ExcretionCefadroxil is excreted primarily unchanged in the urine by glomerular filtration and tubular secretion. Probenecid is excreted in the urine as metabolites and unchanged drug.
BioavailabilityCefadroxil has a bioavailability of about 90% when taken orally. Probenecid bioavailability is also high, approximately 90%.
Onset of ActionAntibacterial effects begin within 1 to 2 hours after oral administration.
Peak Plasma TimePeak plasma concentrations of cefadroxil are reached within 1 to 2 hours. Probenecid peaks in about 2 to 4 hours.
Duration of ActionThe antibacterial effect lasts for about 12 hours, allowing for twice-daily dosing. Probenecid's effect on uric acid excretion lasts longer.

How It Works

Cefadroxil works by binding to penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting the final step of peptidoglycan synthesis. This weakens the cell wall and leads to bacterial cell lysis and death. Probenecid inhibits the renal tubular secretion of cefadroxil by competing for the same organic anion transporter, thereby increasing the plasma concentration and prolonging the half-life of cefadroxil. This allows for less frequent dosing or higher effective levels of the antibiotic.

Mechanism Steps

1
Cefadroxil binds to PBPs: Cefadroxil binds to penicillin-binding proteins on the bacterial cell membrane, inhibiting cell wall synthesis.
2
Bacterial cell lysis: The weakened cell wall leads to osmotic lysis and death of the bacteria.
3
Probenecid inhibits renal secretion: Probenecid competes with cefadroxil for the organic anion transporter in the kidney tubules, reducing its excretion.
4
Increased cefadroxil levels: As a result, cefadroxil plasma concentrations remain higher for longer, enhancing its antibacterial effect.

💡 How to Take mydrox 500mg/500mg tablet

Strength: Tablet containing cefadroxil 500 mg and probenecid 500 mg.

1Take the tablet with a full glass of water.
2Swallow it whole; do not crush or chew.
3Take with food to reduce stomach upset.
4Take at the same times each day.
5Complete the full course as prescribed.

Dosage Information

Adult DosageThe usual adult dose is one tablet (cefadroxil 500 mg + probenecid 500 mg) taken orally twice daily, or as prescribed by your doctor. The dose may be adjusted based on the type and severity of infection, kidney function, and other factors. Always follow your doctor's instructions. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Consult your doctor.
Renal ImpairmentDose adjustment is required in patients with renal impairment. Consult your doctor for appropriate dosing.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 2 tablets (cefadroxil 1000 mg + probenecid 1000 mg) per day, unless otherwise prescribed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Meals
Take with food
Reduces stomach upset.
Alcohol
Avoid
May increase side effects.

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of mydrox 500mg/500mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or contains blood, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Rash (Uncommon (1-5%))
Stop the medicine and consult your doctor if rash develops.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, or difficulty breathing.
Stevens-Johnson syndrome (Rare (<0.1%))
Seek immediate medical attention if you develop a severe blistering rash, peeling skin, or sores in the mouth.
Aplastic anemia (Rare (<0.1%))
Report unusual fatigue, bruising, or bleeding to your doctor immediately.
Acute kidney injury (Rare (<0.1%))
Seek medical attention if you notice decreased urine output, swelling, or confusion.

⚠️ Rare Side Effects

Agranulocytosis
Report sudden fever, sore throat, or mouth ulcers to your doctor immediately.
Hepatitis
Seek medical attention if you notice yellowing of eyes or skin, dark urine, or severe abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Methotrexate Major
Warfarin Major
Furosemide Moderate
NSAIDs Moderate
Antacids Minor

🚨 Major Interactions

  • Methotrexate
  • Warfarin

⚡ Moderate Interactions

  • Loop diuretics (e.g., furosemide)
  • NSAIDs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it may increase the risk of stomach upset, dizziness, and liver problems.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cephalosporins or probenecid","Severe renal impairment","Blood dyscrasias","Children under 2 years","Pregnancy (relative)"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment.","May cause false-positive results in urine glucose tests.","Avoid in patients with a history of penicillin allergy due to cross-reactivity.","Probenecid may precipitate acute gout.","Do not use for viral infections like the common cold.","Complete the full course as prescribed."]

🤱 Lactation Safety

Cefadroxil and probenecid are excreted in breast milk in small amounts. Consult your doctor before breastfeeding while on this medicine.

💊 Overdose Management

Overdose may cause nausea, vomiting, and diarrhea. Seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better, as this can lead to antibiotic resistance. Take each dose with a full glass of water and preferably with food to reduce stomach upset. Avoid alcohol while taking this medicine. Drink plenty of fluids to help prevent kidney stones. Inform your doctor if you have a history of kidney disease, liver disease, gout, or blood disorders. Do not take this medicine if you are allergic to cephalosporins or probenecid. If you experience a rash, swelling, or difficulty breathing, seek emergency medical help immediately. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more likely to have reduced kidney function and may require dose adjustments. Monitor renal function closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor before planning pregnancy while on this medicine. Both cefadroxil and probenecid are generally considered safe in pregnancy, but medical advice is essential.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before surgery. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may affect bleeding risk and interact with other medications.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water to stay hydrated.
🥗
Maintain a healthy diet rich in fruits and vegetables.
😴
Get adequate rest to support your immune system.
💧
Practice good hygiene to prevent infections.
🧘
Avoid alcohol and smoking.
🌞
Take probiotics if you experience diarrhea.

🏋️ Exercise Considerations

If you experience dizziness or fatigue, avoid strenuous exercise or operating heavy machinery until you know how this medicine affects you.

🥗 Diet Recommendations

Stay well hydrated.
Include probiotic-rich foods like yogurt.
Avoid spicy and oily foods if you have stomach upset.
Limit alcohol intake.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating machinery if you feel unwell. Most people can continue their normal activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of kidney problems, blood disorders, and antibiotic resistance. Regular monitoring of kidney function, liver function, and blood counts is recommended if used for prolonged periods. Consult your doctor for periodic evaluations.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Cefadroxil alone

May be used if probenecid is not tolerated, but may require more frequent dosing.

Evidence: Well-established
Other antibiotics

Depending on the infection and susceptibility, other antibiotics may be prescribed.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, antibiotics may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Consult your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine twice daily for 7 days. She took it with meals and completed the course. Her symptoms improved within 3 days, and she felt completely better by the end of the week.
💡 Lesson: Taking the medicine with food and completing the full course led to a successful outcome.
👤 A 60-year-old man with a skin infection
He had a history of gout and was cautious about probenecid. His doctor monitored his uric acid levels and adjusted his diet. He completed the course without any gout flare-ups.
💡 Lesson: With proper monitoring and hydration, patients with gout can safely take this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2-3 days, but you must complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, take it with food to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip it and continue your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for mydrox 500mg/500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the flu.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections.
  • Myth: You can stop taking this medicine once you feel better.
    Fact: You must complete the full course to prevent resistance and recurrence.

📊 Comparison with Similar Medicines

[{"medicine":"Cefadroxil alone","difference":"Lacks probenecid, so shorter duration of action."},{"medicine":"Amoxicillin + probenecid","difference":"Different antibiotic class; may be used for similar infections."}]

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