ltc kit - Tinidazole (500mg) + Clarithromycin (250mg) medicine

Heligo 500 mg/250 mg Kit: Complete Medicine Guide

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🏭 Ind Swift Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for specific indications.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding
  • Palpitations or fainting

If experiencing severe symptoms, call emergency services immediately.

What is ltc kit used for?

This medicine is a prescription antibiotic kit containing Tinidazole 500 mg and Clarithromycin 250 mg. It is used to treat certain bacterial and protozoal infections, often as part of Helicobacter pylori eradication therapy. It must be taken exactly as prescribed, and alcohol must be avoided during and for 72 hours after treatment.

  • Generic Name: Tinidazole (500mg) + Clarithromycin (250mg)
  • Manufacturer: Ind Swift Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ltc kit के बारे में (Hindi Summary)

उपयोग: यह दवा टिनिडाजोल 500 मिलीग्राम और क्लैरिथ्रोमाइसिन 250 मिलीग्राम का संयोजन है। इसका उपयोग कुछ बैक्टीरियल और प्रोटोज़ोअल संक्रमणों के इलाज के लिए किया जाता है, विशेष रूप से हेलिकोबैक्टर पाइलोरी के उन्मूलन में। यह दांतों और पेट के संक्रमण में भी दी जाती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, धातु जैसा स्वाद, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, लिवर की समस्या, रक्त विकार और हृदय की धड़कन में बदलाव हो सकते हैं। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। बीच में न छोड़ें। इलाज के दौरान और आखिरी खुराक के 72 घंटे बाद तक शराब बिल्कुल न लें। दवा को भोजन के साथ लें। चक्कर आने पर वाहन न चलाएं। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 ltc kit Uses & Benefits

  • [{"condition":"Helicobacter pylori eradication","description":"Used as part of combination therapy with acid suppressants and other antibiotics to eradicate H.
  • pylori infection in peptic ulcer disease.","evidence":"Well-established"},{"condition":"Dental infections","description":"Used for mixed aerobic-anaerobic dental abscesses and periodontal infections when a combination is needed.","evidence":"Moderate"},{"condition":"Gastrointestinal infections","description":"Used for certain protozoal and bacterial gastrointestinal infections, including giardiasis and amoebiasis when combined with other agents.","evidence":"Moderate"},{"condition":"Respiratory tract infections","description":"Clarithromycin component covers atypical and typical respiratory pathogens; combination may be used in selected cases.","evidence":"Limited"}]

Off-label uses: [{"condition":"Rosacea","description":"Clarithromycin component has been used off-label for inflammatory rosacea.","evidence":"Limited"},{"condition":"Chronic periodontitis","description":"Combination may be used off-label as an adjunct to mechanical debridement.","evidence":"Limited"}]

Primary treatment for: Helicobacter pylori infection

Also treats: Dental infections, Gastrointestinal infections, Respiratory tract infections

📋 Drug Information

Generic Name(s)Tinidazole (500mg) + Clarithromycin (250mg)
Brand Nameltc kit
ManufacturerInd Swift Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep in the original packaging.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol completely during treatment and for 72 hours after the last dose.
3
Complete the full course even if you feel better after a few days.
4
Inform your doctor about all other medicines you are taking, especially blood thinners and heart medicines.
5
Do not drive or operate machinery if you feel dizzy.
6
Report any signs of allergic reaction, such as rash or swelling, immediately.
7
Take the tablets at evenly spaced intervals as prescribed.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Stomach pain and bloating
This medicine is commonly prescribed for H. pylori infection.
Likely Use
Dental abscess
This medicine may be used for dental infections.
Likely Use
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTinidazole is rapidly and completely absorbed after oral administration. Clarithromycin is also well absorbed from the gastrointestinal tract, with bioavailability around 50-55%.
DistributionTinidazole distributes widely into body tissues and fluids, including cerebrospinal fluid. Clarithromycin distributes widely and achieves high intracellular concentrations.
Protein BindingTinidazole is approximately 12% protein-bound. Clarithromycin is about 70-80% protein-bound.
MetabolismTinidazole undergoes hepatic metabolism, mainly by oxidation and conjugation. Clarithromycin is metabolized in the liver by CYP3A4 to an active metabolite, 14-hydroxyclarithromycin.
Half-LifeTinidazole half-life is approximately 12-14 hours. Clarithromycin half-life is approximately 3-4 hours, and its active metabolite has a longer half-life.
ExcretionTinidazole is excreted mainly in urine and feces. Clarithromycin is excreted in urine and feces, with about 20-30% unchanged in urine.
BioavailabilityTinidazole oral bioavailability is high, approaching 100%. Clarithromycin oral bioavailability is approximately 50-55%.
Onset of ActionAntimicrobial effects begin within hours of the first dose, but clinical improvement may take 1-3 days.
Peak Plasma TimeTinidazole peak plasma concentration occurs about 2 hours after oral dose. Clarithromycin peak occurs about 2-3 hours after oral dose.
Duration of ActionAntimicrobial activity persists for at least 12-24 hours depending on the organism and dose.

How It Works

Tinidazole enters susceptible microorganisms and undergoes reductive activation, producing reactive intermediates that damage DNA and inhibit nucleic acid synthesis. Clarithromycin binds reversibly to the 50S ribosomal subunit and inhibits bacterial protein synthesis by blocking translocation and peptide bond formation. Together they provide broad coverage against anaerobic bacteria, protozoa, and atypical respiratory pathogens.

Mechanism Steps

1
Tinidazole uptake and activation: Tinidazole diffuses into susceptible microorganisms where its nitro group is reduced, creating reactive radicals.
2
DNA damage: The reactive intermediates bind to and break microbial DNA, blocking replication and transcription.
3
Clarithromycin ribosomal binding: Clarithromycin binds to the 50S subunit of the bacterial ribosome and inhibits protein synthesis.
4
Combined antimicrobial effect: The two agents act on different targets, leading to inhibition or death of susceptible organisms.

💡 How to Take ltc kit

Strength: Kit containing Tinidazole 500 mg and Clarithromycin 250 mg tablets.

1Take this medicine orally with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow the tablets whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Avoid alcohol completely during and for 72 hours after treatment.
6Complete the full course even if you feel better.

Dosage Information

Adult DosageThe dose of this medicine must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Typically, one kit is taken orally as directed by the doctor, often twice daily or as part of a combination regimen. Do not self-adjust the dose. Complete the full course as prescribed.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects. Dose adjustment may be needed based on renal and hepatic function. Consult a doctor.
Renal ImpairmentDose adjustment may be required in severe renal impairment. Clarithromycin should be used with caution. Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with liver disease. Dose reduction may be necessary. Monitor liver function. Consult a doctor.
Maximum Daily DoseNot established from the available information. Follow the prescribed dose strictly.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid completely
Can cause disulfiram-like reaction.
Grapefruit juice
Avoid
May increase clarithromycin levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ltc kit

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food and stay hydrated. Consult doctor if persistent.
Metallic taste (Common (5-10%))
Usually temporary. Chewing sugar-free gum may help.
Diarrhea (Common (5-10%))
Drink fluids. Seek medical advice if severe or bloody.
Headache (Common (5-10%))
Rest and hydrate. Consult doctor if severe.
Abdominal pain (Common (5-10%))
Take with food. Report if severe or persistent.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you have swelling of face, lips, throat, or difficulty breathing.
Liver inflammation (hepatitis) (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain immediately.
Blood disorders (e.g., leukopenia, thrombocytopenia) (Rare (<0.1%))
Report unusual bruising, bleeding, or fever to your doctor.
Heart rhythm changes (QT prolongation) (Rare (<0.1%))
Seek medical attention if you experience palpitations, dizziness, or fainting.
Seizures (Rare (<0.1%))
Call emergency services if a seizure occurs.

⚠️ Rare Side Effects

Peripheral neuropathy
Report numbness, tingling, or weakness in hands or feet.
Severe skin reactions (Stevens-Johnson syndrome)
Seek emergency care for rash with blisters or peeling skin.
Pancreatitis
Seek immediate care for severe upper abdominal pain radiating to back.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ergotamine Major
Simvastatin Major
Amiodarone Major
Carbamazepine Moderate
Phenytoin Moderate
Theophylline Moderate
Digoxin Moderate
Oral contraceptives Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Ergot alkaloids (e.g., ergotamine)
  • Statins (simvastatin, atorvastatin)
  • QT-prolonging drugs (e.g., amiodarone, sotalol)
  • Disulfiram

⚡ Moderate Interactions

  • Carbamazepine
  • Phenytoin
  • Theophylline
  • Digoxin
  • Oral contraceptives

🍷 Alcohol Interaction

Alcohol must be strictly avoided during treatment with this medicine and for at least 72 hours after the last dose. Tinidazole can cause a disulfiram-like reaction with symptoms such as severe nausea, vomiting, flushing, headache, and rapid heartbeat. Clarithromycin may also interact with alcohol to increase liver stress.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to tinidazole, clarithromycin, or other macrolides","Severe liver disease","History of QT prolongation or ventricular arrhythmias","Use with ergot alkaloids","Use with disulfiram within 2 weeks","Pregnancy (especially first trimester) unless clearly needed","Breastfeeding during treatment and for 72 hours after"]

⚠️ Warnings & Precautions

["Avoid alcohol during and for 72 hours after treatment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have heart, liver, or kidney disease.","May interact with many medicines; provide a full list to your doctor.","Complete the full course as prescribed to prevent resistance.","Do not use for viral infections like the common cold.","Report any signs of allergic reaction immediately."]

🤱 Lactation Safety

Tinidazole and clarithromycin are excreted in breast milk. Breastfeeding is not recommended during treatment and for at least 72 hours after the last dose. Consult your doctor for alternatives.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, diarrhea, and dizziness. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed. Do not skip doses or stop early, even if you feel better. Avoid alcohol completely during treatment and for at least 72 hours after the last dose. Take with food to reduce stomach upset. Inform your doctor about all other medicines, especially blood thinners, heart medicines, and seizure medicines. Do not drive or operate machinery if you feel dizzy. Complete the full course to prevent resistance. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more prone to side effects such as dizziness, liver toxicity, and heart rhythm changes. Dose adjustment may be needed based on kidney and liver function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed. Use effective contraception during treatment.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with certain anesthetic agents.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may be prescribed for dental infections, but interactions with other medicines used during dental procedures should be considered.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy diet rich in fruits and vegetables.
🥗
Stay well hydrated throughout the day.
😴
Avoid alcohol completely during and after treatment.
💧
Get adequate rest to support recovery.
🧘
Practice good hygiene to prevent reinfection.
🌞
Follow up with your doctor as advised.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or weak. Light activity is fine if you feel well. Consult your doctor before resuming intense workouts.

🥗 Diet Recommendations

Eat small, frequent meals to reduce stomach upset.
Include probiotic-rich foods like yogurt to support gut health.
Avoid spicy and oily foods that may irritate the stomach.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities with caution.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full course as prescribed. If you experience severe side effects, contact your doctor immediately for advice.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may increase the risk of antibiotic resistance, liver toxicity, and blood disorders. Regular monitoring of liver and kidney function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

May help reduce antibiotic-associated diarrhea when taken alongside antibiotics.

Evidence: Moderate
Good oral hygiene

Helps prevent dental infections.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the effectiveness of live vaccines. Consult your doctor about vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Avoid alcohol during travel. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with recurrent stomach pain and bloating
He was diagnosed with H. pylori infection and prescribed this medicine as part of a combination regimen. He took it with food twice daily and avoided alcohol completely. After completing the course, his symptoms improved significantly, and follow-up tests showed eradication of the infection.
💡 Lesson: Taking the full course as prescribed and avoiding alcohol are essential for successful treatment.
👤 A 32-year-old woman with a dental abscess
She was prescribed this medicine after a dental procedure. She experienced mild nausea and a metallic taste, which resolved after taking it with meals. She completed the course and her infection cleared without complications.
💡 Lesson: Taking the medicine with food can reduce common side effects like nausea and metallic taste.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-3 days, but you must complete the full course as prescribed.

Q: Can I stop taking it if I feel better?

A: No, you must complete the full course to prevent resistance and ensure the infection is fully treated.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for ltc kit

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any infection.
    Fact: It only works for specific bacterial and protozoal infections. It is not effective against viral infections like the common cold.
  • Myth: You can stop taking it once you feel better.
    Fact: You must complete the full course to prevent resistance and ensure cure.
  • Myth: Alcohol is safe in small amounts.
    Fact: Alcohol can cause a severe reaction with Tinidazole. Avoid completely during and for 72 hours after treatment.

🔄 Alternative Options

Generic Alternatives

  • Tinidazole 500 mg + Clarithromycin 250 mg combination kit

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Tinidazole 500 mg + Clarithromycin 250 mg","use":"H. pylori, dental, GI infections","notes":"Avoid alcohol"},{"medicine":"Amoxicillin + Clarithromycin kit","composition":"Amoxicillin + Clarithromycin","use":"H. pylori","notes":"Penicillin allergy caution"}]

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