Addie Cold Oral Suspension: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Yellowing of the skin or eyes (jaundice)
- Severe abdominal pain or persistent vomiting
- Blood in vomit or stool
- Unusual bleeding or bruising
- Decreased urine output
- Severe drowsiness or confusion
If experiencing severe symptoms, call emergency services immediately.
What is loract d syrup used for?
This medicine is a combination of chlorpheniramine maleate (an antihistamine) and paracetamol (a pain reliever and fever reducer) used to treat symptoms of common cold and allergies such as runny nose, sneezing, and mild fever.
- Generic Name: Chlorpheniramine Maleate (0.5mg/5ml) + Paracetamol (125mg/5ml)
- Manufacturer: Organic Laboratories
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 loract d syrup के बारे में (Hindi Summary)
उपयोग: यह दवा सर्दी-जुकाम और एलर्जी के लक्षणों जैसे नाक बहना, छींक आना, आंखों में खुजली और हल्के बुखार के इलाज के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन मेलिएट और पैरासिटामोल दो सक्रिय तत्व हैं। क्लोरफेनिरामाइन एलर्जी को कम करता है और पैरासिटामोल दर्द और बुखार को कम करता है। यह दवा 6 साल से बड़े बच्चों और वयस्कों के लिए है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, जी मिचलाना और कब्ज शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि आपको त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा की अनुशंसित खुराक से अधिक न लें। इस दवा को लेते समय शराब का सेवन न करें क्योंकि इससे नींद और लीवर की समस्या बढ़ सकती है। बिना डॉक्टर की सलाह के 7 दिनों से अधिक इसका उपयोग न करें। यदि आपको लीवर या किडनी की बीमारी है तो डॉक्टर से परामर्श लें। बच्चों की पहुंच से दूर रखें।
💊 loract d syrup Uses & Benefits
[{"condition":"Common cold","description":"Relieves symptoms such as runny nose, sneezing, and mild fever associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Reduces sneezing, rhinorrhea, and itching of the nose and throat due to allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps relieve itching and hives associated with allergic skin reactions.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Common cold and allergic rhinitis
Also treats: Urticaria, Allergic conjunctivitis
📋 Drug Information
| Generic Name(s) | Chlorpheniramine Maleate (0.5mg/5ml) + Paracetamol (125mg/5ml) |
| Brand Name | loract d syrup |
| Manufacturer | Organic Laboratories |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines an antihistamine and an analgesic-antipyretic. Chlorpheniramine maleate competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract, thereby reducing allergic symptoms. Paracetamol acts primarily in the central nervous system to produce analgesia and antipyresis, likely through inhibition of prostaglandin synthesis in the brain.
Mechanism Steps
💡 How to Take loract d syrup
Strength: Each 5 ml contains chlorpheniramine maleate 0.5 mg and paracetamol 125 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 10 ml (2 teaspoons) every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of chlorpheniramine, especially drowsiness and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Consult a doctor. |
| Hepatic Impairment | Dose adjustment may be required in patients with hepatic impairment. Consult a doctor. |
| Maximum Daily Dose | For adults: maximum 6 doses (60 ml) in 24 hours. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of loract d syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Alcohol | Major | |
| MAOIs | Major | |
| CNS depressants | Moderate | |
| Anticholinergics | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Other paracetamol-containing products
- Alcohol
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- CNS depressants (e.g., benzodiazepines, opioids)
- Warfarin
- Anticholinergic drugs (e.g., tricyclic antidepressants)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase drowsiness and the risk of liver damage, especially due to the paracetamol component.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, paracetamol, or any component of the formulation","Severe liver disease","Newborns and premature infants","Patients taking MAOIs"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Do not exceed recommended dose due to risk of liver damage.","Avoid alcohol while taking this medicine.","Use with caution in patients with glaucoma, urinary retention, or asthma.","Consult a doctor if symptoms persist beyond 7 days."]
🤱 Lactation Safety
Chlorpheniramine and paracetamol are excreted in breast milk. Caution is advised. Consult a doctor before use.
💊 Overdose Management
Overdose can cause severe liver damage due to paracetamol. Symptoms may include nausea, vomiting, abdominal pain, and confusion. Seek immediate medical attention. Treatment may include administration of N-acetylcysteine as an antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Do not exceed the recommended dose of this medicine. Avoid consuming alcohol or other central nervous system depressants while taking this medicine, as it can increase drowsiness. Do not use this medicine for more than 7 days without consulting a doctor. If you have liver or kidney disease, consult your doctor before use. Do not take other products containing paracetamol while on this medicine to avoid overdose. Keep out of reach of children. Pregnant and breastfeeding women should consult a doctor before use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the anticholinergic and sedative effects of chlorpheniramine. They may also be at higher risk of liver or kidney problems from paracetamol. Use with caution and consider lower doses. Consult a doctor for appropriate dosing.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination in pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery. Paracetamol may be used for pain relief, but the antihistamine component may cause drowsiness.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and interact with other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how the medicine affects you. Light activities like walking are generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive, operate machinery, or perform tasks requiring mental alertness. It is advisable to avoid such activities until you know how the medicine affects you. If your work requires alertness, discuss with your doctor about timing the dose or alternative options.
🛑 When to Stop This Medicine
Stop taking this medicine and consult a doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as allergic reactions or signs of liver problems. Do not stop abruptly if you have been taking it regularly for a long time without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of paracetamol can increase the risk of liver and kidney damage. Chlorpheniramine may cause tolerance and anticholinergic effects. Regular monitoring of liver and kidney function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps relieve nasal congestion without medication.
Evidence: Well-establishedFor allergic conjunctivitis, may provide targeted relief.
Evidence: Well-establishedCan help loosen mucus and relieve congestion.
Evidence: Traditional💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription to avoid issues at customs. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking the medicine as prescribed, but adjust the timing gradually to the new local schedule. Do not leave it in a hot car or checked luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose.
A: You should avoid taking other cold medicines that contain paracetamol or antihistamines to prevent overdose and increased side effects. Always consult your doctor or pharmacist before combining.
A: This medicine is not recommended for children under 6 years without consulting a pediatrician. For children 6 years and older, the dose should be determined by a doctor based on weight and condition.
A: Yes, drowsiness is a common side effect due to the chlorpheniramine component. Avoid driving or operating machinery until you know how this medicine affects you.
🤔 Common Patient Concerns
🔄 Substitutes for loract d syrup
View AllAlternative brands with exact same active ingredient:
-
adlemef p syrupAdvok Pharmacia Private Limited ₹36.00 3% CHEAPER
-
dracold syrupDrams Healthcare ₹36.00 3% CHEAPER
-
johncold syrupShiron Pharmaceuticals ₹42.19 13.6% COSTLIER
-
yoricold syrupRoseate Medicare ₹42.19 13.6% COSTLIER
-
Rosecold Kid SyrupRoseate Medicare ₹42.19 13.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the recommended dose can lead to serious liver damage from paracetamol.
🔄 Alternative Options
Generic Alternatives
- Chlorpheniramine + Paracetamol oral suspension