limet myo 500mg/550mg tablet - Metformin (500mg) + Myo-Inositol (550mg) medicine

Limet Myo 500mg/550mg Tablet: Complete Guide

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🏭 Cheminnova Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 26, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Metformin: Well-established. Myo-inositol: Emerging evidence.
Reviewed by
SaathiMed Expert Panel | Sep 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Muscle pain or difficulty breathing
  • Extreme fatigue or weakness
  • Severe abdominal pain
  • Yellowing of skin or eyes
  • Decreased urine output
  • Rash or swelling of face, lips, or throat

If experiencing severe symptoms, call emergency services immediately.

What is limet myo 500mg/550mg tablet used for?

This medicine is a combination of Metformin and Myo-Inositol used to treat type 2 diabetes and PCOS. It helps lower blood sugar and improve insulin sensitivity. Take it with meals as prescribed by your doctor.

  • Generic Name: Metformin (500mg) + Myo-Inositol (550mg)
  • Manufacturer: Cheminnova Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 limet myo 500mg/550mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा मेटफॉर्मिन और मायो-इनोसिटोल का संयोजन है, जिसका उपयोग टाइप 2 डायबिटीज और पीसीओएस (पॉलीसिस्टिक ओवरी सिंड्रोम) के इलाज में किया जाता है। यह ब्लड शुगर को कंट्रोल करने और इंसुलिन सेंसिटिविटी को बेहतर बनाने में मदद करती है। इसे डॉक्टर की सलाह के अनुसार भोजन के साथ लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, पेट की गड़बड़ी और मुंह में धातु जैसा स्वाद शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन लैक्टिक एसिडोसिस हो सकता है, जिसमें मांसपेशियों में दर्द, सांस लेने में कठिनाई और अत्यधिक थकान हो सकती है। ऐसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक खुद से न बदलें। इसे भोजन के साथ लें ताकि पेट की गड़बड़ी कम हो। पर्याप्त पानी पिएं। शराब का सेवन न करें क्योंकि इससे लैक्टिक एसिडोसिस का खतरा बढ़ सकता है। अगर आपको किडनी या लिवर की समस्या है तो डॉक्टर को बताएं। नियमित रूप से ब्लड शुगर की जांच करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 limet myo 500mg/550mg tablet Uses & Benefits

[{"condition":"Type 2 Diabetes Mellitus","description":"Helps lower blood glucose levels by improving insulin sensitivity and reducing hepatic glucose production.","evidence":"Well-established for metformin component"},{"condition":"Polycystic Ovary Syndrome (PCOS)","description":"May improve insulin resistance and support ovulation in women with PCOS.","evidence":"Emerging evidence for myo-inositol component"},{"condition":"Insulin Resistance","description":"Both components may help improve insulin sensitivity in individuals with metabolic syndrome.","evidence":"Moderate evidence"}]

Off-label uses: [{"condition":"Gestational Diabetes","description":"Sometimes prescribed off-label for gestational diabetes, but only under specialist care.","evidence":"Limited"},{"condition":"Weight Management","description":"May be used off-label to support weight management in insulin-resistant individuals.","evidence":"Limited"}]

Primary treatment for: Type 2 Diabetes Mellitus

Also treats: Polycystic Ovary Syndrome (PCOS), Insulin Resistance

📋 Drug Information

Generic Name(s)Metformin (500mg) + Myo-Inositol (550mg)
Brand Namelimet myo 500mg/550mg tablet
ManufacturerCheminnova Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineMetformin is recommended as first-line therapy for type 2 diabetes by many guidelines, but specific recommendations for this combination are not established.
ICMR GuidelineICMR guidelines recommend metformin as first-line for type 2 diabetes. Myo-inositol is not specifically included in national guidelines for diabetes.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to minimize stomach upset.
2
Monitor your blood sugar levels regularly as advised.
3
Stay well hydrated throughout the day.
4
Avoid alcohol while taking this medicine.
5
Inform your doctor if you have kidney or liver problems.
6
Do not stop this medicine without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood sugar
This medicine is commonly prescribed for this.
Likely Use
✅
Irregular periods
May be used in PCOS with insulin resistance.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionMetformin is absorbed primarily from the small intestine. Bioavailability is approximately 50-60% under fasting conditions. Food decreases the rate but not the extent of absorption. Myo-inositol is absorbed from the gastrointestinal tract.
DistributionMetformin is widely distributed in body tissues, with a volume of distribution of about 654 L. It does not bind significantly to plasma proteins. Myo-inositol is distributed in various tissues, including the brain and reproductive organs.
Protein BindingMetformin is negligibly bound to plasma proteins. Myo-inositol does not bind to plasma proteins.
MetabolismMetformin is not metabolized in the liver. It is excreted unchanged in the urine. Myo-inositol is metabolized in the kidneys and other tissues.
Half-LifeThe elimination half-life of metformin is approximately 6.2 hours. The half-life of myo-inositol is not well established.
ExcretionMetformin is excreted unchanged in the urine via active tubular secretion. Myo-inositol is excreted in the urine.
BioavailabilityMetformin bioavailability is 50-60%. Myo-inositol bioavailability is not well established.
Onset of ActionMetformin's glucose-lowering effect begins within days but may take up to 2 weeks for full effect. Myo-inositol's effects on insulin sensitivity may take several weeks.
Peak Plasma TimeMetformin reaches peak plasma concentration in 2-3 hours. Myo-inositol peak time is not well established.
Duration of ActionMetformin's effect lasts for about 24 hours. Myo-inositol's duration is not well established.

How It Works

Metformin works by inhibiting mitochondrial complex I in the liver, which reduces hepatic gluconeogenesis. It also increases insulin sensitivity in peripheral tissues by enhancing glucose uptake. Myo-inositol acts as a precursor for phosphatidylinositol, which is involved in insulin signaling pathways. It helps improve insulin sensitivity and ovarian function by modulating intracellular calcium and inositol phosphate metabolism.

Mechanism Steps

1
Metformin uptake into hepatocytes: Metformin enters liver cells via organic cation transporters (OCT1).
2
Inhibition of mitochondrial complex I: Inside the mitochondria, metformin inhibits complex I, leading to reduced ATP production and increased AMP levels.
3
Activation of AMPK: The increased AMP/ATP ratio activates AMPK, which switches off energy-consuming processes like gluconeogenesis.
4
Reduced hepatic glucose output: This results in decreased glucose production by the liver.
5
Myo-inositol uptake and conversion: Myo-inositol is taken up by cells and converted to phosphatidylinositol, a key component of cell membranes and signaling.
6
Improved insulin signaling: Myo-inositol enhances insulin signaling by increasing the availability of inositol phosphates, which are involved in glucose uptake.

💡 How to Take limet myo 500mg/550mg tablet

Strength: Tablet containing Metformin 500 mg and Myo-Inositol 550 mg.

1Take the tablet with a full glass of water.
2Take it with meals to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow your doctor's instructions on timing and frequency.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally once or twice daily with meals. The exact dose and frequency must be individualized by a qualified clinician based on indication, blood sugar levels, renal and hepatic function, and response to treatment. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Monitor renal function regularly.
Renal ImpairmentDose adjustment is required in renal impairment. Contraindicated if eGFR <30 mL/min/1.73 m2. Consult your doctor.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose of metformin is 2000 mg. The maximum dose of myo-inositol in this combination is 1100 mg (if taken twice daily). Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With meals
Take with food
Reduces stomach upset and improves tolerability.
Alcohol
Avoid
Increases risk of lactic acidosis.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of limet myo 500mg/550mg tablet

✅ Common Side Effects

Nausea (Common (10-20%))
Take with food. If persistent, consult your doctor.
Diarrhea (Common (10-20%))
Stay hydrated. Consult doctor if severe or persistent.
Metallic taste (Common (5-10%))
Usually resolves on its own. Chewing sugar-free gum may help.

🚨 Serious Side Effects

Lactic acidosis (Rare (<0.1%))
Seek immediate medical attention if you experience muscle pain, difficulty breathing, or extreme fatigue.
Vitamin B12 deficiency (Uncommon (1-5%))
Monitor B12 levels periodically. Supplement if deficient.

⚠️ Rare Side Effects

Allergic reaction
Seek immediate medical help if you notice rash, itching, swelling, or difficulty breathing.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Iodinated contrast media Major
Alcohol Major
Diuretics Moderate
Corticosteroids Moderate
Cimetidine Minor

🚨 Major Interactions

  • Iodinated contrast media
  • Alcohol

⚡ Moderate Interactions

  • Diuretics
  • Corticosteroids

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it increases the risk of lactic acidosis and may worsen blood sugar control.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe renal impairment (eGFR

⚠️ Warnings & Precautions

["Risk of lactic acidosis in patients with renal impairment, liver disease, or dehydration.","Temporarily discontinue before surgery or contrast imaging.","Monitor vitamin B12 levels with long-term use.","Avoid excessive alcohol consumption.","Use with caution in elderly patients."]

🤱 Lactation Safety

Metformin is excreted in breast milk in small amounts. It is generally considered safe during breastfeeding. Myo-inositol is likely safe. Consult your doctor.

💊 Overdose Management

Overdose may cause lactic acidosis. Seek immediate medical attention. Treatment includes supportive care, hemodialysis if necessary.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose without consulting your clinician. Take it with meals to reduce stomach upset. Stay well hydrated. Avoid excessive alcohol consumption as it increases the risk of lactic acidosis. Inform your doctor if you have kidney or liver problems. Monitor your blood sugar regularly as advised. Do not stop taking this medicine suddenly without medical advice. If you are scheduled for surgery or a contrast imaging procedure, inform your doctor as this medicine may need to be temporarily stopped.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and are at higher risk of lactic acidosis. Regular monitoring of renal function is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor. This medicine may be continued or adjusted based on your condition.

🏥 Post-Surgery Considerations

This medicine may need to be temporarily stopped before surgery. Inform your surgeon and anesthesiologist.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. No specific precautions are usually needed, but maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight.
🥗
Exercise regularly, at least 30 minutes most days.
😴
Eat a balanced diet rich in fiber and low in refined sugars.
💧
Monitor your blood sugar as advised.
🧘
Get adequate sleep.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Exercise is encouraged, but if you experience dizziness or weakness, stop and consult your doctor. Stay hydrated during exercise.

🥗 Diet Recommendations

Include whole grains, fruits, and vegetables.
Limit sugary drinks and processed foods.
Choose lean proteins.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery if you feel dizzy. Otherwise, it should not affect your daily activities.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use may lead to vitamin B12 deficiency, so periodic monitoring is advised. Kidney function should be checked regularly. Lactic acidosis is rare but serious. Regular follow-up with your doctor is important.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet and exercise are essential for managing diabetes and PCOS.

Evidence: Well-established
Other antidiabetic medications

Your doctor may prescribe other medicines if this combination is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before any vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep enough supply for the entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with PCOS and insulin resistance
She was prescribed this medicine by her gynecologist. After 3 months, she noticed more regular periods and improved energy levels. She took it regularly with breakfast and dinner.
💡 Lesson: Consistency and taking with food improves tolerability and outcomes.
👤 A 50-year-old man with type 2 diabetes
He started this medicine along with lifestyle changes. His HbA1c dropped from 8.5% to 7.2% over 6 months. He experienced mild nausea initially, which resolved after taking it with meals.
💡 Lesson: Taking with meals reduces side effects and helps achieve better blood sugar control.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Metformin starts working within days, but full effects on blood sugar may take 1-2 weeks. Myo-inositol's effects on insulin sensitivity may take several weeks.

Q: Can I take this medicine if I have kidney disease?

A: It depends on the severity. It is contraindicated in severe renal impairment. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure diabetes permanently.
    Fact: This medicine helps manage blood sugar levels but does not cure diabetes. Lifestyle changes and medication are needed for long-term control.
  • Myth: You can stop taking this medicine once your sugar levels are normal.
    Fact: Do not stop without consulting your doctor. Stopping suddenly can cause blood sugar to rise again.

🔄 Alternative Options

Generic Alternatives

  • Metformin 500 mg + Myo-Inositol 550 mg tablet

Brand Alternatives

  • Limet Myo 500mg/550mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Metformin alone","difference":"Does not contain myo-inositol; used primarily for diabetes."},{"medicine":"Myo-Inositol alone","difference":"Used primarily for PCOS; does not lower blood sugar as effectively as metformin."}]

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