lidocyn plus injection - Lidocaine (NA) medicine

Alocaine Injection: Complete Medicine Guide

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🏭 Harson Laboratories 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 29, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for local anaesthesia and ventricular arrhythmias.
Reviewed by
SaathiMed Expert Panel | Oct 29, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Seizures or convulsions
  • Severe dizziness or fainting
  • Irregular or slow heartbeat
  • Chest pain
  • Persistent numbness or weakness in the injected area
  • Signs of infection at the injection site (redness, warmth, pus)

If experiencing severe symptoms, call emergency services immediately.

What is lidocyn plus injection used for?

This medicine is a local anaesthetic injection containing lidocaine. It is used to numb a specific area of the body before surgery, dental work, or other procedures. It works by blocking pain signals in nerves. It is given only by a healthcare professional.

  • Generic Name: Lidocaine (NA)
  • Manufacturer: Harson Laboratories
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lidocyn plus injection के बारे में (Hindi Summary)

उपयोग: यह दवा एक स्थानीय एनेस्थेटिक इंजेक्शन है जिसमें लिडोकेन होता है। इसका उपयोग सर्जरी, दांतों के इलाज या अन्य प्रक्रियाओं से पहले शरीर के एक विशिष्ट हिस्से को सुन्न करने के लिए किया जाता है। यह दर्द के संकेतों को नसों में रोककर काम करती है। यह केवल एक स्वास्थ्य पेशेवर द्वारा दी जाती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा, सूजन, चक्कर आना, नींद आना और धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, दौरे, अनियमित दिल की धड़कन और कार्डियक अरेस्ट शामिल हो सकते हैं। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल एक प्रशिक्षित स्वास्थ्य पेशेवर द्वारा एक चिकित्सा सेटिंग में दी जानी चाहिए। इंजेक्शन लेने से पहले अपने सभी चिकित्सीय हालात और एलर्जी के बारे में डॉक्टर को बताएं। इंजेक्शन के बाद तब तक वाहन न चलाएं जब तक आप पूरी तरह सतर्क न हों। 24 घंटे तक शराब से बचें। इंजेक्शन स्थल को साफ और सूखा रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 lidocyn plus injection Uses & Benefits

[{"condition":"Local anaesthesia for minor surgical procedures","description":"This medicine is injected to numb a specific area of skin or tissue before procedures such as suturing, biopsy, or minor surgery.","evidence":"Well-established"},{"condition":"Dental procedures","description":"It is used to numb the gums and teeth before dental work such as fillings, extractions, or root canal treatment.","evidence":"Well-established"},{"condition":"Nerve blocks","description":"It can be used for regional nerve blocks to provide pain relief during and after certain surgeries or for diagnostic purposes.","evidence":"Well-established"},{"condition":"Ventricular arrhythmias","description":"Intravenous lidocaine is used in emergency settings to treat certain life-threatening heart rhythm disturbances.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Chronic pain management","description":"Sometimes injected for trigger point injections or sympathetic blocks for chronic pain conditions.","evidence":"Limited"},{"condition":"Migraine treatment","description":"Occasionally used for greater occipital nerve blocks to relieve acute migraine attacks.","evidence":"Limited"}]

Primary treatment for: Local anaesthesia for surgical and dental procedures

Also treats: Ventricular arrhythmias, Nerve blocks for pain management

📋 Drug Information

Generic Name(s)Lidocaine (NA)
Brand Namelidocyn plus injection
ManufacturerHarson Laboratories
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassLocal anaesthetic (Amides)
Route of AdministrationParenteral (injection)
StorageStore at room temperature between 15°C and 30°C. Protect from light and freezing. Keep in the original container.
Shelf LifeTypically 24 to 36 months from the date of manufacture, depending on the specific product. Check the expiry date on the label.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always administer this medicine in a setting with resuscitation equipment.
2
Aspirate before injecting to avoid accidental intravascular injection.
3
Use the lowest effective dose to minimize the risk of toxicity.
4
Monitor patients for at least 30 minutes after injection for any adverse effects.
5
Avoid using adrenaline-containing solutions in areas with poor blood supply, such as fingers or toes.
6
In elderly patients, reduce the dose and monitor closely for CNS effects.
7
Inform patients not to drive or operate machinery until fully alert.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Pain during minor surgical procedure
This medicine is commonly used for this purpose.
Likely Use
✅
Dental pain during procedure
This medicine is used for dental anaesthesia.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Chronic joint pain
This medicine is not typically used for chronic joint pain unless injected for specific nerve blocks.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is given by injection, so absorption is not applicable in the usual sense. When injected into tissue, it diffuses locally and is taken up by blood vessels. Systemic absorption depends on the site of injection, dose, and presence of a vasoconstrictor like adrenaline.
DistributionAfter absorption, lidocaine is distributed widely throughout the body. It crosses the blood-brain barrier and the placenta. It has a volume of distribution of approximately 1.1 to 2.1 L/kg in adults.
Protein BindingAbout 60% to 80% of lidocaine is bound to plasma proteins, mainly alpha-1-acid glycoprotein and albumin.
MetabolismLidocaine is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4 and CYP1A2. The main metabolites are monoethylglycinexylidide (MEGX) and glycinexylidide (GX), which have some pharmacological activity.
Half-LifeThe elimination half-life of lidocaine is approximately 1.5 to 2 hours in healthy adults. It may be prolonged in patients with liver disease or heart failure.
ExcretionLess than 10% of lidocaine is excreted unchanged in the urine. The majority is excreted as metabolites in the urine.
BioavailabilityNot applicable for injection. When given intravenously, bioavailability is 100%. For local infiltration, systemic bioavailability depends on the dose and site.
Onset of ActionThe onset of anaesthesia is rapid, usually within 1 to 5 minutes after injection, depending on the site and technique.
Peak Plasma TimePeak plasma concentration is reached within 5 to 30 minutes after injection, depending on the site and dose.
Duration of ActionThe anaesthetic effect typically lasts 30 to 60 minutes without a vasoconstrictor, and up to 2 to 3 hours when combined with adrenaline.

How It Works

This medicine works by blocking voltage-gated sodium channels on the inner side of nerve cell membranes. When these channels are blocked, sodium ions cannot enter the nerve cell, which prevents the nerve from generating and conducting an electrical impulse. This reversible blockade stops pain signals from travelling along the nerve to the brain, resulting in loss of sensation in the area supplied by that nerve. At higher concentrations, it can also affect the heart and central nervous system.

Mechanism Steps

1
Diffusion to nerve membrane: After injection, the medicine diffuses through the tissue to reach the nerve cell membrane.
2
Binding to sodium channels: It binds to the intracellular side of voltage-gated sodium channels in the nerve membrane.
3
Blockade of sodium influx: This binding prevents sodium ions from entering the nerve cell during depolarization.
4
Inhibition of nerve impulse: Without sodium influx, the nerve cannot generate an action potential, so pain signals are blocked.
5
Reversible anaesthesia: The effect is temporary and wears off as the medicine is redistributed and metabolized.

💡 How to Take lidocyn plus injection

Strength: This medicine is available as an injection in various strengths, commonly 1% (10 mg/mL) and 2% (20 mg/mL) solutions. The specific strength depends on the product.

1This medicine is given by a healthcare professional as an injection.
2You do not need to do anything to prepare for the injection.
3Inform your doctor about any allergies or medical conditions before receiving it.
4After the injection, remain in the clinic for a short period for monitoring.
5Do not drive or operate machinery until you are fully alert.

Dosage Information

Adult DosageThe dose of this medicine depends on the procedure, the area to be numbed, and the patient's weight and health status. For local infiltration, a common adult dose is 1 to 5 mL of 1% or 2% solution, but the maximum safe dose is usually 4.5 mg/kg without adrenaline and 7 mg/kg with adrenaline. For nerve blocks, doses vary widely. For ventricular arrhythmias, an initial intravenous dose of 1 to 1.5 mg/kg may be given, followed by a maintenance infusion. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. Doses are weight-based and must be calculated by a qualified clinician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Doses should be reduced, and the lowest effective dose should be used. Monitoring for toxicity is recommended.
Renal ImpairmentNo specific dose adjustment is usually required for mild to moderate kidney disease. In severe kidney disease, metabolites may accumulate, and caution is advised. Consult a clinician for individualized dosing.
Hepatic ImpairmentIn patients with liver disease, the half-life of this medicine is prolonged. Dose reduction is recommended, and the lowest effective dose should be used. Monitor for signs of toxicity.
Maximum Daily DoseThe maximum safe dose is generally 4.5 mg/kg without adrenaline and 7 mg/kg with adrenaline. For intravenous use, the maximum total dose is usually 300 mg over 1 hour. Doses must be individualized by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Grapefruit juice
Avoid large amounts
May increase lidocaine levels by inhibiting CYP3A4.
Alcohol
Avoid for 24 hours
Increases drowsiness and risk of heart effects.

⏰ What to Do If You Miss a Dose

📌 This medicine is given as a single dose by a healthcare professional.
→ Missed dose instructions are not applicable.
💡 If you miss a scheduled appointment for a repeat injection, contact your doctor to reschedule.

⚠️ Side Effects of lidocyn plus injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Usually resolves on its own. Apply a cold pack if needed.
Redness or swelling at injection site (Common (5-10%))
Keep the area clean and avoid rubbing. Consult if it worsens.
Dizziness (Common (1-5%))
Sit or lie down until it passes. Avoid driving.
Drowsiness (Common (1-5%))
Rest and avoid operating machinery.
Metallic taste (Uncommon (0.1-1%))
Usually goes away quickly. Drink water.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help immediately if you have swelling of face, lips, throat, or difficulty breathing.
Seizures (Rare (<0.1%))
Requires immediate medical attention. Do not attempt to drive yourself.
Cardiac arrest or irregular heartbeat (Rare (<0.1%))
Call emergency services immediately. This can happen with high doses or accidental intravascular injection.
Persistent nerve damage (Rare (<0.1%))
Report persistent numbness, weakness, or tingling to your doctor.
Severe low blood pressure (Rare (<0.1%))
Seek immediate medical care if you feel faint, have cold clammy skin, or rapid heartbeat.

⚠️ Rare Side Effects

Methaemoglobinaemia
Seek emergency care if you notice bluish lips or skin, shortness of breath, or confusion.
Transient blindness or double vision
Report to your doctor immediately.
Tinnitus (ringing in ears)
Inform your doctor if it persists.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Cimetidine Major
Propranolol Major
Tocainide Major
Bupivacaine Moderate
Morphine Moderate
Diazepam Moderate
Ritonavir Minor
Ketoconazole Minor
Grapefruit juice Minor
Alcohol Moderate

🚨 Major Interactions

  • Class I antiarrhythmics (e.g., tocainide, mexiletine)
  • Cimetidine
  • Beta-blockers (e.g., propranolol, metoprolol)

⚡ Moderate Interactions

  • Other local anaesthetics (e.g., bupivacaine, prilocaine)
  • Opioid analgesics (e.g., morphine, fentanyl)
  • Sedatives (e.g., benzodiazepines)

🍷 Alcohol Interaction

Alcohol should be avoided for at least 24 hours after receiving this medicine. Alcohol can increase drowsiness, dizziness, and the risk of heart rhythm problems. It may also worsen the effects of lidocaine on the central nervous system.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to lidocaine or other amide local anaesthetics","Severe heart block without a pacemaker","Severe liver disease","Porphyria","Hypovolemia or shock","Use in areas with poor blood supply or infection"]

⚠️ Warnings & Precautions

["This medicine should only be administered by trained healthcare professionals.","Resuscitation equipment and drugs must be immediately available.","Use with caution in patients with epilepsy, heart disease, or liver disease.","Avoid accidental injection into blood vessels.","Do not use in large doses or for prolonged periods without monitoring.","Elderly patients may be more sensitive to the effects.","Children should receive doses based on weight and age."]

🤱 Lactation Safety

Lidocaine is excreted in breast milk in small amounts. It is generally considered safe for breastfeeding mothers when used in single doses for local anaesthesia. Avoid applying to the breast area before feeding to prevent infant exposure.

💊 Overdose Management

Overdose of this medicine can cause severe CNS and cardiac toxicity. Symptoms include seizures, coma, respiratory depression, slow heart rate, and cardiac arrest. Treatment is supportive and symptomatic. There is no specific antidote. Management includes maintaining airway, breathing, and circulation, giving oxygen, and using anticonvulsants for seizures. Intravenous lipid emulsion therapy may be used in severe cases. Immediate hospitalization is required.

⏰ Missed Dose

This medicine is given as a single dose or a series of doses by a healthcare professional. Missed dose instructions are not applicable. If you miss a scheduled appointment for a repeat injection, contact your doctor to reschedule.

Additional Safety Advice

General Safety

This medicine must only be given by a trained healthcare professional in a properly equipped medical setting. Before receiving this injection, tell your doctor about all your medical conditions, especially heart, liver, or kidney problems, and any allergies you have. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery immediately after receiving this injection until you are sure you are fully alert. Avoid alcohol for at least 24 hours after the procedure, as it can increase drowsiness and affect your heart. Do not rub or scratch the injection site, and keep it clean and dry. If you notice any unusual symptoms such as severe dizziness, difficulty breathing, or chest pain after leaving the clinic, seek emergency medical help right away.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine. Lower doses are recommended, and monitoring for dizziness, confusion, and heart effects is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, inform your doctor before receiving this medicine. It is generally considered safe when used as directed, but should only be used when clearly needed.

🏥 Post-Surgery Considerations

After surgery, this medicine may be used for post-operative pain relief through nerve blocks. Follow your surgeon's instructions for activity and wound care.

🦷 Dental Procedures

This medicine is commonly used in dental procedures to numb the gums and teeth. Inform your dentist if you have any allergies or heart conditions.

💚 Lifestyle Tips for Better Results

🏃
Follow your doctor's instructions for post-procedure care.
🥗
Avoid alcohol for 24 hours after receiving this medicine.
😴
Do not drive or operate machinery until fully alert.
💧
Keep the injection site clean and dry.
🧘
Report any unusual symptoms to your doctor promptly.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting for at least 24 hours after receiving this medicine, especially if it was given for a nerve block or joint procedure. Consult your doctor before resuming exercise.

🥗 Diet Recommendations

Stay well hydrated
Avoid alcohol for 24 hours
Eat a light meal before the procedure unless instructed otherwise

💼 Impact on Daily Work & Life

This medicine can cause drowsiness and dizziness, so you should not drive or operate heavy machinery until you are fully alert. It is best to arrange for someone to drive you home after the procedure. Most people can resume normal activities the next day.

🛑 When to Stop This Medicine

This medicine is given as a single dose or short course by a healthcare professional. You do not need to stop it yourself. If you experience any severe side effects, inform your doctor immediately.

📅 Long-Term Use Effects

Long-term effects of this medicine are not well established for single or occasional use. Repeated injections may cause local tissue damage or nerve injury. Prolonged intravenous use for arrhythmias requires monitoring of liver and heart function. There is no evidence of long-term harm when used appropriately for local anaesthesia.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other local anaesthetics

Bupivacaine or prilocaine may be used as alternatives depending on the procedure.

Evidence: Well-established
General anaesthesia

For some procedures, general anaesthesia may be used instead of local anaesthesia.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for a vaccination, inform your doctor about the injection.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

If you are prescribed this medicine for travel, carry it in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, follow your doctor&#039;s instructions for timing. Declare it at customs if required. This medicine is for professional use only and should not be self-administered during travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man undergoing a dental extraction
He received this medicine as a local anaesthetic before a tooth extraction. The procedure was painless, and the numbness wore off in about an hour. He experienced mild dizziness for a few minutes but it resolved on its own.
💡 Lesson: This medicine provides effective pain relief for dental procedures, and side effects are usually mild and temporary.
👤 A 60-year-old woman with a minor skin biopsy
She was given this medicine before a skin biopsy on her arm. The injection stung briefly, but the area became numb quickly. She was advised not to drive home and to avoid alcohol for 24 hours.
💡 Lesson: Following post-injection instructions, such as avoiding driving and alcohol, is important for safety.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 1 to 5 minutes after injection.

Q: How long will the numbness last?

A: The numbness typically lasts 30 to 60 minutes without adrenaline, and up to 2 to 3 hours with adrenaline.

Q: Can I eat before receiving this injection?

A: Yes, you can eat normally unless your doctor advises otherwise for the procedure.

Q: Is this medicine safe for children?

A: It can be used in children under medical supervision, with doses based on weight.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How long does the numbness last?
  • Is it safe in pregnancy?
  • Can I drive after receiving this injection?
  • What if I have an allergic reaction?
  • Does it interact with my heart medicines?

🔄 Substitutes for lidocyn plus injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken at home.
    Fact: This medicine is an injection and must only be given by a healthcare professional in a medical setting.
  • Myth: It is safe to drive immediately after the injection.
    Fact: You should not drive until you are fully alert, as it can cause drowsiness and dizziness.
  • Myth: It is addictive.
    Fact: This medicine is not addictive when used as directed for local anaesthesia.

🔄 Alternative Options

Generic Alternatives

  • Lidocaine injection

Brand Alternatives

  • Alocaine injection

📊 Comparison with Similar Medicines

[{"medicine":"Lidocaine","onset":"Fast (1-5 min)","duration":"30-60 min (up to 3 hrs with adrenaline)","use":"Local anaesthesia, arrhythmias"},{"medicine":"Bupivacaine","onset":"Slow (5-10 min)","duration":"2-8 hours","use":"Long-acting local anaesthesia"},{"medicine":"Prilocaine","onset":"Fast (2-5 min)","duration":"30-60 min","use":"Local anaesthesia, less vasodilation"}]

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