Alocaine Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Seizures or convulsions
- Severe dizziness or fainting
- Irregular or slow heartbeat
- Chest pain
- Persistent numbness or weakness in the injected area
- Signs of infection at the injection site (redness, warmth, pus)
If experiencing severe symptoms, call emergency services immediately.
What is lcaine injection used for?
This medicine is a local anaesthetic injection containing lidocaine. It is used to numb a specific area of the body before surgery, dental work, or other procedures. It works by blocking pain signals in nerves. It is given only by a healthcare professional.
- Generic Name: Lidocaine (NA)
- Manufacturer: Group Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lcaine injection के बारे में (Hindi Summary)
उपयोग: यह दवा एक स्थानीय एनेस्थेटिक इंजेक्शन है जिसमें लिडोकेन होता है। इसका उपयोग सर्जरी, दांतों के इलाज या अन्य प्रक्रियाओं से पहले शरीर के एक विशिष्ट हिस्से को सुन्न करने के लिए किया जाता है। यह दर्द के संकेतों को नसों में रोककर काम करती है। यह केवल एक स्वास्थ्य पेशेवर द्वारा दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा, सूजन, चक्कर आना, नींद आना और धातु जैसा स्वाद शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, दौरे, अनियमित दिल की धड़कन और कार्डियक अरेस्ट शामिल हो सकते हैं। कोई भी गंभीर लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल एक प्रशिक्षित स्वास्थ्य पेशेवर द्वारा एक चिकित्सा सेटिंग में दी जानी चाहिए। इंजेक्शन लेने से पहले अपने सभी चिकित्सीय हालात और एलर्जी के बारे में डॉक्टर को बताएं। इंजेक्शन के बाद तब तक वाहन न चलाएं जब तक आप पूरी तरह सतर्क न हों। 24 घंटे तक शराब से बचें। इंजेक्शन स्थल को साफ और सूखा रखें।
💊 lcaine injection Uses & Benefits
[{"condition":"Local anaesthesia for minor surgical procedures","description":"This medicine is injected to numb a specific area of skin or tissue before procedures such as suturing, biopsy, or minor surgery.","evidence":"Well-established"},{"condition":"Dental procedures","description":"It is used to numb the gums and teeth before dental work such as fillings, extractions, or root canal treatment.","evidence":"Well-established"},{"condition":"Nerve blocks","description":"It can be used for regional nerve blocks to provide pain relief during and after certain surgeries or for diagnostic purposes.","evidence":"Well-established"},{"condition":"Ventricular arrhythmias","description":"Intravenous lidocaine is used in emergency settings to treat certain life-threatening heart rhythm disturbances.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Chronic pain management","description":"Sometimes injected for trigger point injections or sympathetic blocks for chronic pain conditions.","evidence":"Limited"},{"condition":"Migraine treatment","description":"Occasionally used for greater occipital nerve blocks to relieve acute migraine attacks.","evidence":"Limited"}]
Primary treatment for: Local anaesthesia for surgical and dental procedures
Also treats: Ventricular arrhythmias, Nerve blocks for pain management
📋 Drug Information
| Generic Name(s) | Lidocaine (NA) |
| Brand Name | lcaine injection |
| Manufacturer | Group Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Local anaesthetic (Amides) |
| Route of Administration | Parenteral (injection) |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and freezing. Keep in the original container. |
| Shelf Life | Typically 24 to 36 months from the date of manufacture, depending on the specific product. Check the expiry date on the label. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking voltage-gated sodium channels on the inner side of nerve cell membranes. When these channels are blocked, sodium ions cannot enter the nerve cell, which prevents the nerve from generating and conducting an electrical impulse. This reversible blockade stops pain signals from travelling along the nerve to the brain, resulting in loss of sensation in the area supplied by that nerve. At higher concentrations, it can also affect the heart and central nervous system.
Mechanism Steps
💡 How to Take lcaine injection
Strength: This medicine is available as an injection in various strengths, commonly 1% (10 mg/mL) and 2% (20 mg/mL) solutions. The specific strength depends on the product.
Dosage Information
| Adult Dosage | The dose of this medicine depends on the procedure, the area to be numbed, and the patient's weight and health status. For local infiltration, a common adult dose is 1 to 5 mL of 1% or 2% solution, but the maximum safe dose is usually 4.5 mg/kg without adrenaline and 7 mg/kg with adrenaline. For nerve blocks, doses vary widely. For ventricular arrhythmias, an initial intravenous dose of 1 to 1.5 mg/kg may be given, followed by a maintenance infusion. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Doses are weight-based and must be calculated by a qualified clinician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Doses should be reduced, and the lowest effective dose should be used. Monitoring for toxicity is recommended. |
| Renal Impairment | No specific dose adjustment is usually required for mild to moderate kidney disease. In severe kidney disease, metabolites may accumulate, and caution is advised. Consult a clinician for individualized dosing. |
| Hepatic Impairment | In patients with liver disease, the half-life of this medicine is prolonged. Dose reduction is recommended, and the lowest effective dose should be used. Monitor for signs of toxicity. |
| Maximum Daily Dose | The maximum safe dose is generally 4.5 mg/kg without adrenaline and 7 mg/kg with adrenaline. For intravenous use, the maximum total dose is usually 300 mg over 1 hour. Doses must be individualized by a clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lcaine injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Cimetidine | Major | |
| Propranolol | Major | |
| Tocainide | Major | |
| Bupivacaine | Moderate | |
| Morphine | Moderate | |
| Diazepam | Moderate | |
| Ritonavir | Minor | |
| Ketoconazole | Minor | |
| Grapefruit juice | Minor | |
| Alcohol | Moderate |
🚨 Major Interactions
- Class I antiarrhythmics (e.g., tocainide, mexiletine)
- Cimetidine
- Beta-blockers (e.g., propranolol, metoprolol)
⚡ Moderate Interactions
- Other local anaesthetics (e.g., bupivacaine, prilocaine)
- Opioid analgesics (e.g., morphine, fentanyl)
- Sedatives (e.g., benzodiazepines)
🍷 Alcohol Interaction
Alcohol should be avoided for at least 24 hours after receiving this medicine. Alcohol can increase drowsiness, dizziness, and the risk of heart rhythm problems. It may also worsen the effects of lidocaine on the central nervous system.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to lidocaine or other amide local anaesthetics","Severe heart block without a pacemaker","Severe liver disease","Porphyria","Hypovolemia or shock","Use in areas with poor blood supply or infection"]
⚠️ Warnings & Precautions
["This medicine should only be administered by trained healthcare professionals.","Resuscitation equipment and drugs must be immediately available.","Use with caution in patients with epilepsy, heart disease, or liver disease.","Avoid accidental injection into blood vessels.","Do not use in large doses or for prolonged periods without monitoring.","Elderly patients may be more sensitive to the effects.","Children should receive doses based on weight and age."]
🤱 Lactation Safety
Lidocaine is excreted in breast milk in small amounts. It is generally considered safe for breastfeeding mothers when used in single doses for local anaesthesia. Avoid applying to the breast area before feeding to prevent infant exposure.
💊 Overdose Management
Overdose of this medicine can cause severe CNS and cardiac toxicity. Symptoms include seizures, coma, respiratory depression, slow heart rate, and cardiac arrest. Treatment is supportive and symptomatic. There is no specific antidote. Management includes maintaining airway, breathing, and circulation, giving oxygen, and using anticonvulsants for seizures. Intravenous lipid emulsion therapy may be used in severe cases. Immediate hospitalization is required.
⏰ Missed Dose
This medicine is given as a single dose or a series of doses by a healthcare professional. Missed dose instructions are not applicable. If you miss a scheduled appointment for a repeat injection, contact your doctor to reschedule.
Additional Safety Advice
This medicine must only be given by a trained healthcare professional in a properly equipped medical setting. Before receiving this injection, tell your doctor about all your medical conditions, especially heart, liver, or kidney problems, and any allergies you have. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not drive or operate heavy machinery immediately after receiving this injection until you are sure you are fully alert. Avoid alcohol for at least 24 hours after the procedure, as it can increase drowsiness and affect your heart. Do not rub or scratch the injection site, and keep it clean and dry. If you notice any unusual symptoms such as severe dizziness, difficulty breathing, or chest pain after leaving the clinic, seek emergency medical help right away.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Lower doses are recommended, and monitoring for dizziness, confusion, and heart effects is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, inform your doctor before receiving this medicine. It is generally considered safe when used as directed, but should only be used when clearly needed.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used for post-operative pain relief through nerve blocks. Follow your surgeon's instructions for activity and wound care.
🦷 Dental Procedures
This medicine is commonly used in dental procedures to numb the gums and teeth. Inform your dentist if you have any allergies or heart conditions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting for at least 24 hours after receiving this medicine, especially if it was given for a nerve block or joint procedure. Consult your doctor before resuming exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and dizziness, so you should not drive or operate heavy machinery until you are fully alert. It is best to arrange for someone to drive you home after the procedure. Most people can resume normal activities the next day.
🛑 When to Stop This Medicine
This medicine is given as a single dose or short course by a healthcare professional. You do not need to stop it yourself. If you experience any severe side effects, inform your doctor immediately.
📅 Long-Term Use Effects
Long-term effects of this medicine are not well established for single or occasional use. Repeated injections may cause local tissue damage or nerve injury. Prolonged intravenous use for arrhythmias requires monitoring of liver and heart function. There is no evidence of long-term harm when used appropriately for local anaesthesia.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Bupivacaine or prilocaine may be used as alternatives depending on the procedure.
Evidence: Well-establishedFor some procedures, general anaesthesia may be used instead of local anaesthesia.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for a vaccination, inform your doctor about the injection.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
If you are prescribed this medicine for travel, carry it in its original packaging with the prescription label clearly visible. Keep a copy of your prescription with you. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, follow your doctor's instructions for timing. Declare it at customs if required. This medicine is for professional use only and should not be self-administered during travel.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 1 to 5 minutes after injection.
A: The numbness typically lasts 30 to 60 minutes without adrenaline, and up to 2 to 3 hours with adrenaline.
A: Yes, you can eat normally unless your doctor advises otherwise for the procedure.
A: It can be used in children under medical supervision, with doses based on weight.
🤔 Common Patient Concerns
🔄 Substitutes for lcaine injection
View AllAlternative brands with exact same active ingredient:
-
zelcaine injectionPCI Pharmaceuticals ₹15.54 44.8% CHEAPER
-
alocaine injectionAlembic Pharmaceuticals Ltd ₹16.88 40% CHEAPER
-
zylo injectionLupin Ltd ₹21.09 25% CHEAPER
-
lidocyn plus injectionHarson Laboratories ₹41.50 47.5% COSTLIER
-
nircaine injectionNirlife Healthcare ₹80.92 187.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken at home.
Fact: This medicine is an injection and must only be given by a healthcare professional in a medical setting. - Myth: It is safe to drive immediately after the injection.
Fact: You should not drive until you are fully alert, as it can cause drowsiness and dizziness. - Myth: It is addictive.
Fact: This medicine is not addictive when used as directed for local anaesthesia.
🔄 Alternative Options
Generic Alternatives
- Lidocaine injection
Brand Alternatives
- Alocaine injection