lemo suspension - Chlorpheniramine Maleate (NA) + Phenylephrine (125mg) medicine

Lemo Suspension: Complete Medicine Guide

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🏭 Yash Pharma Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
🤰 Pregnancy Category Chlorpheniramine and phenylephrine are not recommended for use during pregnancy unless clearly needed. Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for allergic rhinitis and common cold.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swallowing
  • Swelling of the face, lips, tongue, or throat
  • Rapid, irregular, or pounding heartbeat
  • Severe dizziness or fainting
  • Seizures or hallucinations
  • Inability to urinate
  • Severe headache with blurred vision

If experiencing severe symptoms, call emergency services immediately.

What is lemo suspension used for?

This medicine is a combination of chlorpheniramine (an antihistamine) and phenylephrine (a decongestant) used to relieve symptoms of allergies and the common cold, such as runny nose, sneezing, and nasal congestion.

  • Generic Name: Chlorpheniramine Maleate (NA) + Phenylephrine (125mg)
  • Manufacturer: Yash Pharma Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lemo suspension के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी-जुकाम के लक्षणों जैसे नाक बहना, छींक आना, नाक बंद होना और आंखों में खुजली को कम करने के लिए इस्तेमाल की जाती है। इसमें क्लोरफेनिरामाइन (एंटीहिस्टामिन) और फेनाइलएफ्रिन (डिकंजेस्टेंट) होते हैं। यह दवा डॉक्टर की सलाह पर ही लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, चक्कर आना, सिरदर्द और जी मिचलाना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, तेज धड़कन या पेशाब में रुकावट हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को लेते समय गाड़ी चलाने या मशीन चलाने से बचें क्योंकि इससे नींद आ सकती है। शराब न पिएं। अगर आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड, ग्लूकोमा या पेशाब में रुकावट है तो डॉक्टर को बताएं। 14 दिनों के भीतर MAOI दवा ली हो तो यह दवा न लें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 lemo suspension Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides temporary relief of nasal congestion, sneezing, and runny nose due to the common cold.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps reduce nasal stuffiness and pressure in acute or chronic sinusitis.","evidence":"Limited"},{"condition":"Allergic conjunctivitis","description":"Reduces itching and tearing of eyes due to allergies.","evidence":"Limited"}]

Off-label uses: [{"condition":"Pruritus","description":"Sometimes used off-label to relieve itching from various causes due to antihistamine effect.","evidence":"Limited"},{"condition":"Motion sickness","description":"Occasionally used off-label for motion sickness due to anticholinergic properties.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Sinusitis, Allergic conjunctivitis

📋 Drug Information

Generic Name(s)Chlorpheniramine Maleate (NA) + Phenylephrine (125mg)
Brand Namelemo suspension
ManufacturerYash Pharma Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed by your doctor.
2
Shake the bottle well before each use to ensure proper mixing.
3
Use a proper measuring device to avoid inaccurate dosing.
4
Avoid driving or operating machinery until you know how this medicine affects you.
5
Do not take this medicine for more than 7 days without consulting your doctor.
6
Inform your doctor if you have high blood pressure, heart disease, or diabetes.
7
Do not use this medicine if you are taking MAO inhibitors.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Runny nose
This medicine is commonly prescribed for this.
Likely Use
Sneezing
This medicine is commonly prescribed for this.
Likely Use
Nasal congestion
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionChlorpheniramine is well absorbed from the gastrointestinal tract after oral administration. Phenylephrine is also absorbed orally but undergoes extensive first-pass metabolism, reducing its systemic bioavailability.
DistributionChlorpheniramine is widely distributed throughout body tissues and crosses the blood-brain barrier. Phenylephrine distribution is not well characterized but is expected to distribute to vascular tissues.
Protein BindingChlorpheniramine is approximately 70% bound to plasma proteins. Protein binding of phenylephrine is not established from the available information.
MetabolismChlorpheniramine is metabolized in the liver, primarily by cytochrome P450 enzymes, including CYP2D6. Phenylephrine is metabolized in the liver and gut wall by monoamine oxidase and sulfotransferases.
Half-LifeThe elimination half-life of chlorpheniramine is approximately 12 to 43 hours in adults. The elimination half-life of phenylephrine is approximately 2.5 to 3 hours.
ExcretionChlorpheniramine and its metabolites are excreted primarily in the urine. Phenylephrine and its metabolites are also excreted in the urine.
BioavailabilityThe oral bioavailability of chlorpheniramine is approximately 25% to 50%. The oral bioavailability of phenylephrine is low, approximately 38%, due to first-pass metabolism.
Onset of ActionThe onset of action for chlorpheniramine is approximately 30 to 60 minutes after oral administration. Phenylephrine onset is within 15 to 30 minutes.
Peak Plasma TimePeak plasma concentrations of chlorpheniramine are reached in about 2 to 6 hours. Peak plasma concentrations of phenylephrine are reached in about 1 to 2 hours.
Duration of ActionThe duration of action for chlorpheniramine is approximately 4 to 6 hours. Phenylephrine duration is approximately 2 to 4 hours.

How It Works

This medicine combines two active ingredients. Chlorpheniramine maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, reducing allergic symptoms such as sneezing, runny nose, and itching. Phenylephrine is a selective alpha-1 adrenergic receptor agonist that causes vasoconstriction in the nasal mucosa, leading to decreased swelling and congestion. The combination provides relief from both allergic and congestive symptoms.

Mechanism Steps

1
Histamine H1 receptor blockade: Chlorpheniramine binds to H1 receptors on cells, preventing histamine from triggering allergic responses such as sneezing, itching, and increased mucus production.
2
Alpha-1 adrenergic receptor stimulation: Phenylephrine stimulates alpha-1 receptors on blood vessels in the nasal mucosa, causing vasoconstriction and reducing swelling and congestion.
3
Central nervous system effects: Chlorpheniramine crosses the blood-brain barrier and blocks H1 receptors in the brain, leading to sedation and reduced alertness.
4
Anticholinergic effects: Chlorpheniramine also blocks muscarinic receptors, causing dry mouth, dry eyes, and urinary retention in susceptible individuals.

💡 How to Take lemo suspension

Strength: Each 5 mL contains chlorpheniramine maleate 2 mg and phenylephrine hydrochloride 5 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the dose accurately.
3Take orally with or without food.
4Follow the dosage instructions provided by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is 5 mL to 10 mL (1 to 2 teaspoons) every 4 to 6 hours as needed, not to exceed 6 doses in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult a doctor.
Maximum Daily DoseMaximum daily dose for adults is 60 mL (12 teaspoons) in 24 hours. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid
May increase drug levels.
Alcohol
Avoid
Increases drowsiness and dizziness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of lemo suspension

✅ Common Side Effects

Drowsiness (Common (10-20%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth, nose, or throat (Common (5-15%))
Sip water or use sugar-free lozenges. Consult doctor if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if persistent.
Nausea (Common (5-10%))
Take with food or milk. Consult doctor if vomiting occurs.
Nervousness (Common (5-10%))
Limit caffeine intake. Consult doctor if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, tongue, or throat, or difficulty breathing.
Rapid or irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you notice palpitations or chest discomfort.
Difficulty urinating (Rare (<0.1%))
Consult your doctor if you are unable to urinate or have painful urination.
Hallucinations or seizures (Rare (<0.1%))
Seek emergency medical help if you experience confusion, hallucinations, or seizures.
Severe hypertension (Rare (<0.1%))
If you have severe headache, blurred vision, or chest pain, seek immediate medical attention.

⚠️ Rare Side Effects

Blood dyscrasias (e.g., agranulocytosis, thrombocytopenia)
Report unusual bruising, bleeding, or signs of infection to your doctor immediately.
Hepatotoxicity
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or abdominal pain.
Photosensitivity
Use sunscreen and protective clothing when outdoors.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAOIs Major
Tricyclic antidepressants Major
Beta-blockers Major
CNS depressants Moderate
Anticholinergics Moderate
Digoxin Moderate
Caffeine Minor
Antacids Minor

🚨 Major Interactions

  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants
  • Beta-blockers

⚡ Moderate Interactions

  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)
  • Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
  • Digoxin

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can increase drowsiness, dizziness, and impair your ability to drive or operate machinery. It may also increase the risk of central nervous system depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to chlorpheniramine, phenylephrine, or any component of the formulation","Use within 14 days of monoamine oxidase inhibitor therapy","Severe hypertension","Severe coronary artery disease","Narrow-angle glaucoma","Urinary retention","Hyperthyroidism"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with hypertension, heart disease, diabetes, thyroid disorders, glaucoma, or prostate enlargement.","Do not exceed recommended dose.","Not for use in children under 2 years of age without medical advice.","Consult a doctor if symptoms persist beyond 7 days or are accompanied by fever."]

🤱 Lactation Safety

Chlorpheniramine and phenylephrine may pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe drowsiness, seizures, hallucinations, rapid heartbeat, hypertension, or difficulty breathing. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Do not use this medicine for longer than directed without consulting a doctor. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Do not drink alcohol while taking this medicine because it can increase drowsiness and dizziness. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid problems, glaucoma, or difficulty urinating. Do not take this medicine if you have taken a monoamine oxidase inhibitor in the last 14 days. Keep out of reach of children. Do not exceed the recommended dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. Use with caution and consider lower doses. Monitor for confusion, urinary retention, and falls.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medicine during pregnancy has not been fully established.

🏥 Post-Surgery Considerations

Consult your doctor before using this medicine after surgery, as it may interact with anesthetics and other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and affect dental health.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated to reduce dry mouth.
🥗
Avoid alcohol and other CNS depressants.
😴
Get plenty of rest to help your body recover.
💧
Use a humidifier to ease nasal congestion.
🧘
Avoid allergens that trigger your symptoms.

🏋️ Exercise Considerations

Avoid strenuous exercise until you know how this medicine affects you, as it may cause drowsiness and dizziness.

🥗 Diet Recommendations

Drink plenty of fluids.
Avoid caffeine, which may increase nervousness.
Eat a balanced diet to support immune function.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness and impair your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also reduce your alertness, affecting work performance.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to tolerance, dependence, and increased risk of side effects such as drowsiness, dry mouth, and urinary retention. Regular monitoring by a doctor is advised if long-term use is necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal irrigation

Can help relieve nasal congestion without medication.

Evidence: Well-established
Allergen avoidance

Reducing exposure to allergens can decrease allergy symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are ill with a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She was prescribed this medicine for her runny nose and sneezing. She took it as directed and found relief within an hour. She experienced mild drowsiness, so she avoided driving after taking it. She was advised to stop after 5 days as symptoms improved.
💡 Lesson: This medicine effectively relieves allergy symptoms but can cause drowsiness; avoid driving until you know its effects.
👤 A 50-year-old man with common cold
He used this medicine for nasal congestion and sneezing. He noticed significant relief but also experienced dry mouth. He was advised to drink plenty of water and use sugar-free lozenges. He was cautioned not to exceed the recommended dose.
💡 Lesson: Dry mouth is a common side effect; staying hydrated helps manage it.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 to 60 minutes after taking a dose.

Q: Can I take this medicine with other cold medicines?

A: Do not take this medicine with other products containing similar ingredients without consulting your doctor, as it may lead to overdose.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: This medicine can cure the common cold.
    Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take this medicine with alcohol.
    Fact: Alcohol increases drowsiness and dizziness and should be avoided.
  • Myth: More medicine means faster relief.
    Fact: Taking more than the recommended dose can lead to serious side effects and does not provide faster relief.

🔄 Alternative Options

Generic Alternatives

  • Chlorpheniramine + Phenylephrine suspension

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Chlorpheniramine + Phenylephrine","sedation":"High","duration":"4-6 hours"},{"medicine":"Cetirizine + Phenylephrine","active_ingredients":"Cetirizine + Phenylephrine","sedation":"Low","duration":"24 hours"},{"medicine":"Loratadine + Phenylephrine","active_ingredients":"Loratadine + Phenylephrine","sedation":"Low","duration":"24 hours"}]

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