cpm injection - Chlorpheniramine Maleate (NA) medicine

cpm injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Kim Lab ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is cpm injection used for?

Allermin (Chlorpheniramine Maleate) is used to treat RESPIRATORY. It contains Chlorpheniramine Maleate (NA), which Competitive antagonist of histamine at H1 receptor sites, thereby suppressing hi. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Chlorpheniramine Maleate
  • Manufacturer: Kim Lab
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š cpm injection Uses & Benefits

Symptomatic relief of allergic rhinitis, urticaria, angioedema, and other allergic conditions; adjunct in anaphylaxis.

Off-label uses: Motion sickness; insomnia (due to sedative effects); common cold symptoms.

๐Ÿ“‹ Drug Information

Generic Name(s)Chlorpheniramine Maleate
Brand NameAllermin
ManufacturerKim Lab
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassH1 Antihistaminics (First Generation)
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract after oral administration.
DistributionDistributed throughout the body; crosses the blood-brain barrier.
Protein BindingApproximately 72% bound to plasma proteins.
MetabolismExtensively metabolized in the liver via CYP450 enzymes, primarily CYP2D6.
Half-Life12-15 hours in adults; prolonged in renal impairment.
ExcretionPrimarily renal excretion of metabolites; less than 1% excreted unchanged.
BioavailabilityApproximately 25-50% due to first-pass metabolism.
Onset of Action30-60 minutes after oral administration.
Peak Plasma Time2-6 hours after oral administration.
Duration of Action4-6 hours (up to 24 hours for extended-release formulations).

How It Works

Competitive antagonist of histamine at H1 receptor sites, thereby suppressing histamine-mediated allergic symptoms.

Mechanism Steps

1Chlorpheniramine binds to histamine H1 receptors on target cells (e.g., respiratory epithelium, vascular endothelium).
2Competitive antagonism prevents histamine from binding and activating the receptor.
3Inhibition of histamine-mediated vasodilation, increased vascular permeability, and smooth muscle contraction.

๐Ÿ’ก How to Take cpm injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cpm injection

โœ… Common Side Effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Blurred vision
  • Urinary retention
  • Constipation

๐Ÿšจ Serious Side Effects

  • Seizures
  • Hallucinations
  • QT prolongation
  • Torsades de pointes
  • Severe hypotension

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Hemolytic anemia
  • Thrombocytopenia
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
MAOIs Major Increased anticholinergic and CNS depressant effects
CNS depressants Major Additive sedation and respiratory depression
Alcohol Major Enhanced sedative effects
Anticholinergics Moderate Additive anticholinergic effects (dry mouth, urinary retention)
Tricyclic antidepressants Moderate Increased anticholinergic and sedative effects
Antipsychotics Moderate Increased risk of extrapyramidal symptoms and sedation
Phenytoin Minor Possible decreased metabolism of chlorpheniramine
Rifampin Minor Decreased chlorpheniramine levels due to enzyme induction

๐Ÿšจ Major Interactions

  • MAOIs
  • CNS depressants
  • Alcohol

โšก Moderate Interactions

  • Anticholinergics
  • Tricyclic antidepressants
  • Antipsychotics

โ„น๏ธ Minor Interactions

  • Phenytoin
  • Rifampin

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice may increase absorption

๐Ÿท Alcohol Interaction

Increased CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to chlorpheniramine or any component; narrow-angle glaucoma; urinary retention; severe hypertension; coronary artery disease; concurrent MAOI therapy.

๐Ÿ“Š Monitoring Parameters

Monitor for sedation, anticholinergic effects, and blood pressure in elderly or hypertensive patients.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution; may cause drowsiness in infants.

๐Ÿ’Š Overdose Management

Induce emesis or gastric lavage; administer activated charcoal; supportive care; treat hypotension and seizures; physostigmine may reverse anticholinergic symptoms.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cpm injection

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Alternative brands with exact same active ingredient (Chlorpheniramine Maleate (NA)):

Medical Note: Always consult your doctor before switching medications.

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