lb comb 500mg tablet dt - Amoxycillin (500mg) + Lactobacillus (60Million spores) medicine

Amolac Capsule: Complete Medicine Guide

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🏭 Okyano Pharma 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe skin rash with blistering or peeling

If experiencing severe symptoms, call emergency services immediately.

What is lb comb 500mg tablet dt used for?

This medicine is a combination of amoxycillin, an antibiotic, and Lactobacillus, a probiotic. It is used to treat bacterial infections and help prevent antibiotic-associated diarrhea.

  • Generic Name: Amoxycillin (500mg) + Lactobacillus (60Million spores)
  • Manufacturer: Okyano Pharma
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 lb comb 500mg tablet dt के बारे में (Hindi Summary)

उपयोग: यह दवा एक एंटीबायोटिक और प्रोबायोटिक का संयोजन है। इसका उपयोग बैक्टीरियल संक्रमण जैसे श्वसन तंत्र संक्रमण, मूत्र मार्ग संक्रमण, त्वचा संक्रमण और दांतों के संक्रमण के इलाज के लिए किया जाता है। इसमें मौजूद लैक्टोबैसिलस आंतों के अच्छे बैक्टीरिया को बनाए रखने में मदद करता है, जिससे एंटीबायोटिक से होने वाले दस्त का खतरा कम हो सकता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट में असुविधा और त्वचा पर दाने शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, गंभीर त्वचा प्रतिक्रिया और आंतों का गंभीर संक्रमण शामिल हो सकता है। यदि आपको गंभीर दस्त, मल में खून, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। इसे पानी के साथ लें, भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। यदि आपको किडनी या लीवर की समस्या है या एलर्जी है तो डॉक्टर को बताएं। इस दवा के साथ शराब न लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 lb comb 500mg tablet dt Uses & Benefits

  • [{"condition":"Respiratory tract infections","description":"Used to treat bacterial infections of the upper and lower respiratory tract, such as sinusitis, pharyngitis, and community-acquired pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against susceptible bacteria causing uncomplicated urinary tract infections.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Prescribed for bacterial skin infections like cellulitis and abscesses caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Dental infections","description":"Used to treat dental abscesses and other odontogenic infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Helicobacter pylori eradication","description":"Part of combination therapy to eradicate H.
  • pylori in peptic ulcer disease.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used off-label for early Lyme disease in patients who cannot take doxycycline.","evidence":"Limited"},{"condition":"Anthrax prophylaxis","description":"May be used off-label for post-exposure prophylaxis of anthrax in certain situations.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Urinary tract infections, Skin infections, Dental infections

📋 Drug Information

Generic Name(s)Amoxycillin (500mg) + Lactobacillus (60Million spores)
Brand Namelb comb 500mg tablet dt
ManufacturerOkyano Pharma
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineAmoxycillin is included in the WHO Model List of Essential Medicines for the treatment of various bacterial infections.
ICMR GuidelineICMR guidelines recommend amoxycillin for the treatment of community-acquired pneumonia and other susceptible bacterial infections.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full course even if you feel better after a few days.
3
Stay well hydrated throughout the day to help your kidneys flush out the medicine.
4
Avoid alcohol while taking this medicine as it may worsen stomach upset.
5
Do not share this medicine with others, even if they have similar symptoms.
6
Report any unusual bleeding, bruising, or signs of allergic reaction immediately.
7
If you develop severe diarrhea, contact your doctor before taking anti-diarrheal medicines.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough
This medicine is commonly prescribed for respiratory infections.
Likely Use
✅
Burning urination
This medicine is used for urinary tract infections.
Likely Use
❌
Runny nose without fever
This medicine is not effective for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmoxycillin is well absorbed from the gastrointestinal tract after oral administration. Food does not significantly affect the extent of absorption but may delay the time to peak concentration.
DistributionAmoxycillin distributes widely into body tissues and fluids, including the lungs, middle ear, sinuses, and urine. It crosses the placenta and is excreted in breast milk.
Protein BindingAmoxycillin is approximately 17-20% bound to plasma proteins.
MetabolismAmoxycillin is partially metabolized in the liver to inactive metabolites, but a significant portion is excreted unchanged.
Half-LifeThe elimination half-life of amoxycillin is approximately 1 to 1.5 hours in patients with normal renal function.
ExcretionAmoxycillin is primarily excreted unchanged in the urine via glomerular filtration and tubular secretion. A small amount is excreted in bile and feces.
BioavailabilityThe oral bioavailability of amoxycillin is approximately 80-90%.
Onset of ActionThe onset of action is typically within 1 to 2 hours after oral administration, but clinical improvement may take 24 to 48 hours.
Peak Plasma TimePeak plasma concentrations are achieved approximately 1 to 2 hours after oral administration.
Duration of ActionThe duration of action is typically 6 to 8 hours, but dosing is usually every 8 to 12 hours to maintain therapeutic levels.

How It Works

Amoxycillin is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) inside the bacterial cell wall. This binding prevents the cross-linking of peptidoglycan chains, which is essential for cell wall strength and rigidity. As a result, the bacterial cell wall becomes weak and the bacterium undergoes lysis and death. Lactobacillus is a probiotic that helps maintain the natural gut flora, which can be disrupted by antibiotic therapy, thereby reducing the risk of antibiotic-associated diarrhea.

Mechanism Steps

1
Binding to penicillin-binding proteins: Amoxycillin binds to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall.
2
Inhibition of cell wall synthesis: This binding inhibits the transpeptidation reaction, preventing the cross-linking of peptidoglycan strands.
3
Bacterial cell lysis: The weakened cell wall leads to osmotic instability and ultimately bacterial cell lysis and death.
4
Probiotic support: Lactobacillus helps maintain the natural balance of beneficial bacteria in the gut, reducing the risk of antibiotic-associated diarrhea.

💡 How to Take lb comb 500mg tablet dt

Strength: Each capsule contains Amoxycillin 500 mg and Lactobacillus 60 million spores.

1Take the capsule orally with a full glass of water.
2Swallow the capsule whole; do not crush or chew.
3Take with or without food, but taking with food may reduce stomach upset.
4Take at evenly spaced intervals as prescribed.
5Complete the full course of therapy even if you feel better.
6Do not share this medicine with others.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one capsule taken orally every 8 to 12 hours, depending on the severity of the infection and the prescribing doctor's judgment. The dose may need to be adjusted in patients with kidney problems. The duration of treatment varies by infection type, typically 5 to 10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and may require dose adjustment. Consult a doctor for appropriate dosing.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. For creatinine clearance 10-30 mL/min, the dose may be reduced or the interval extended. For creatinine clearance less than 10 mL/min, further reduction is needed. Consult a doctor for specific dosing.
Hepatic ImpairmentNo specific dose adjustment is generally required for hepatic impairment, but caution is advised. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is 3 grams (3000 mg) of amoxycillin, but this may vary based on the infection and medical condition. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No restriction
No significant interaction.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of lb comb 500mg tablet dt

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent or severe.
Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if it persists.
Vomiting (Common (5-10%))
Take with food and fluids. Consult doctor if vomiting is severe or persistent.
Abdominal discomfort (Common (5-10%))
Take with food. Consult doctor if pain is severe.
Skin rash (Common (5-10%))
Consult doctor if rash develops, as it may indicate an allergy.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling of face or throat, or severe dizziness.
Clostridioides difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop severe diarrhea, blood in stool, or abdominal pain.
Stevens-Johnson syndrome (Rare (<0.1%))
Seek immediate medical attention if you develop a severe skin rash with blistering or peeling.
Hepatotoxicity (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.

⚠️ Rare Side Effects

Interstitial nephritis
Seek medical attention if you experience decreased urine output, swelling, or fatigue.
Seizures
Seek immediate medical attention if seizures occur, especially in patients with renal impairment.
Blood dyscrasias
Report any unusual bleeding, bruising, or signs of infection to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Allopurinol Major
Oral contraceptives Moderate
Probenecid Moderate
Tetracyclines Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Allopurinol

⚡ Moderate Interactions

  • Oral contraceptives
  • Probenecid
  • Tetracyclines

🍷 Alcohol Interaction

Alcohol may worsen stomach upset and nausea associated with this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to penicillins or cephalosporins","History of severe allergic reaction to beta-lactam antibiotics","Infectious mononucleosis (may cause rash)","Severe renal impairment without dose adjustment"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; dose adjustment may be required.","May cause Clostridioides difficile-associated diarrhea; if severe diarrhea occurs, discontinue and consult doctor.","May cause allergic reactions; discontinue if rash or other allergic symptoms occur.","Prolonged use may lead to superinfection with resistant organisms.","May interfere with oral contraceptive efficacy; use additional contraception.","Not effective against viral infections like the common cold or flu."]

🤱 Lactation Safety

Amoxycillin is excreted in breast milk in low amounts and is generally considered safe during breastfeeding. Lactobacillus is also considered safe. Consult your doctor before use.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. In severe cases, crystalluria and renal failure may occur. Treatment is symptomatic and supportive. Maintain adequate hydration. Contact a poison control center or emergency room immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Complete the full course to ensure the infection is fully treated. Take the capsule with a full glass of water, with or without food, but taking it with food may reduce stomach upset. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Inform your doctor if you have kidney problems, liver problems, or a history of allergies. Avoid alcohol while taking this medicine as it may worsen stomach upset. Do not share this medicine with others, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and may require dose adjustment. Monitor for signs of toxicity.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Amoxycillin is generally considered safe, but always seek medical advice.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

This medicine may be prescribed before dental procedures to prevent infection in at-risk patients. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy diet rich in fruits and vegetables.
🥗
Stay well hydrated to help flush out the infection.
😴
Get adequate rest to support your immune system.
💧
Practice good hygiene to prevent the spread of infection.
🧘
Avoid sharing personal items like towels and utensils.

🏋️ Exercise Considerations

No specific exercise restrictions while taking this medicine. However, if you feel weak or dizzy, avoid strenuous activities.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to support gut health.
Stay well hydrated.
Avoid alcohol and caffeine which can worsen stomach upset.

💼 Impact on Daily Work & Life

This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or fatigue, avoid these activities until you feel better.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Complete the full prescribed course. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of antibiotics can lead to antibiotic resistance and disruption of gut flora. This medicine includes Lactobacillus to help mitigate gut flora disruption. Prolonged use should be avoided unless prescribed by a doctor. Regular monitoring of renal and hepatic function may be needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotic supplements

Can help maintain gut flora during antibiotic therapy.

Evidence: Well-established
Herbal remedies

Some herbs like garlic may have antibacterial properties, but evidence is limited.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Antibiotics may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor about vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a UTI. She took it with food as advised and completed the 7-day course. Her symptoms improved within 3 days, and she did not experience any stomach upset. She emphasized the importance of finishing the entire course.
💡 Lesson: Taking the medicine with food and completing the full course leads to better outcomes and reduces the risk of recurrence.
👤 A 50-year-old man with a dental abscess
He started this medicine for a dental infection. After 2 days, he felt better and stopped taking it. The infection returned a week later and was more severe. He then completed the full course as prescribed and recovered fully.
💡 Lesson: Stopping antibiotics early can lead to recurrence and resistance. Always complete the prescribed course.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: Is this medicine safe during pregnancy?

A: Amoxycillin is generally considered safe during pregnancy. However, consult your doctor before taking any medicine.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for lb comb 500mg tablet dt

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: Antibiotics only work against bacterial infections. This medicine is not effective against viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full course to prevent the infection from returning and to reduce antibiotic resistance.
  • Myth: Probiotics in antibiotics are not necessary.
    Fact: Lactobacillus helps maintain gut flora and may reduce the risk of antibiotic-associated diarrhea.

🔄 Alternative Options

Generic Alternatives

  • Amoxycillin 500 mg + Lactobacillus 60 million spores capsule

Brand Alternatives

  • Amolac capsule

📊 Comparison with Similar Medicines

[{"medicine":"Amoxycillin alone","difference":"Does not contain Lactobacillus; may have higher risk of diarrhea."},{"medicine":"Amoxycillin + Clavulanic acid","difference":"Broader spectrum; used for resistant infections."}]

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