Alcast Plus 5mg/75mg Tablet SR: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swallowing
- Swelling of face, lips, or throat
- Severe drowsiness or confusion
- Irregular heartbeat or palpitations
- Severe rash or blistering
- Blood in cough or vomit
If experiencing severe symptoms, call emergency services immediately.
What is lazine plus 5 mg/75 mg capsule used for?
This medicine is a combination of Levocetirizine (an antihistamine) and Ambroxol (a mucolytic) used to treat allergic rhinitis with productive cough. It relieves sneezing, runny nose, and helps thin mucus, making it easier to cough up. It is usually taken once or twice daily with food. Avoid alcohol and driving due to drowsiness.
- Generic Name: Levocetirizine (5mg) + Ambroxol (75mg)
- Manufacturer: Hetero Drugs Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lazine plus 5 mg/75 mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एलर्जी और कफ दोनों का इलाज करती है। इसमें लेवोसेटिरिज़िन और एम्ब्रोक्सोल होते हैं। यह एलर्जिक राइनाइटिस, साइनसाइटिस और बलगम वाली खांसी में उपयोग की जाती है। यह छींक, नाक बहना, खुजली और आंखों में पानी आना कम करती है और बलगम को पतला करके बाहर निकालने में मदद करती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, सिरदर्द और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई, दिल की धड़कन अनियमित होना हो सकता है। ऐसा होने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 lazine plus 5 mg/75 mg capsule Uses & Benefits
[{"condition":"Allergic rhinitis with productive cough","description":"Relieves sneezing, runny nose, itching, and helps clear mucus from the airways.","evidence":"Well-established"},{"condition":"Sinusitis with thick mucus","description":"Reduces nasal congestion and thins mucus, promoting drainage.","evidence":"Moderate"},{"condition":"Productive cough due to allergies","description":"Helps loosen phlegm and reduce cough frequency.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Chronic urticaria with respiratory symptoms","description":"Sometimes used off-label for itching and mucus in chronic hives.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis with productive cough
Also treats: Sinusitis, Bronchitis, Chronic obstructive pulmonary disease (COPD) with mucus
📋 Drug Information
| Generic Name(s) | Levocetirizine (5mg) + Ambroxol (75mg) |
| Brand Name | lazine plus 5 mg/75 mg capsule |
| Manufacturer | Hetero Drugs Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Levocetirizine is a selective histamine H1-receptor antagonist that blocks histamine from binding to its receptors, reducing allergic symptoms such as sneezing, itching, and runny nose. Ambroxol is a mucolytic agent that increases the production of serous fluid in the respiratory tract and reduces mucus viscosity, making it easier to cough up. Together, they address both allergic and mucus-related components of respiratory conditions.
Mechanism Steps
💡 How to Take lazine plus 5 mg/75 mg capsule
Strength: Tablet containing Levocetirizine 5 mg and Ambroxol 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, as prescribed by your doctor. The exact dose and frequency depend on the condition being treated, your age, kidney and liver function, and response to therapy. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dizziness. Dose adjustment may be necessary based on renal function. Consult your doctor for appropriate dosing. |
| Renal Impairment | In patients with mild to moderate renal impairment, dose adjustment may be needed. In severe renal impairment (creatinine clearance < 10 mL/min), this medicine is contraindicated. Consult your doctor for dose adjustment based on your kidney function. |
| Hepatic Impairment | No specific dose adjustment is recommended for mild to moderate hepatic impairment. In severe hepatic impairment, use with caution and consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily, but this should not exceed the dose prescribed by your doctor. Do not take more than 2 tablets in 24 hours unless directed by a physician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lazine plus 5 mg/75 mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Opioids | Major | |
| MAO inhibitors | Major | |
| Tricyclic antidepressants | Moderate | |
| Ritonavir | Moderate | |
| Theophylline | Minor |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- MAO inhibitors
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
- Ritonavir
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can enhance the sedative effects of Levocetirizine, leading to increased drowsiness, dizziness, and impaired coordination. This can affect your ability to drive or operate machinery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Levocetirizine, Ambroxol, or any component of the formulation","Severe renal impairment (creatinine clearance < 10 mL/min)","Children under 12 years of age (unless prescribed)","Patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol and other CNS depressants.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with hepatic impairment.","Not recommended for children under 12 years without medical advice.","Elderly patients may be more sensitive to side effects.","Do not exceed the recommended dose."]
🤱 Lactation Safety
Levocetirizine is excreted in breast milk in small amounts and may cause drowsiness in the infant. Ambroxol is also excreted in breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, dizziness, nausea, and in extreme cases, respiratory depression. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Do not consume alcohol while taking this medicine, as it can increase drowsiness and impair your ability to think clearly. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Also, tell your doctor about all other medicines you are taking, especially sedatives, antidepressants, or other antihistamines, as they may interact. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight. Do not use it after the expiry date. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the sedative effects of Levocetirizine. Dose adjustment may be needed based on kidney function. Monitor for dizziness and falls.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Levocetirizine is generally considered safe, but Ambroxol should be used only if clearly needed.
🏥 Post-Surgery Considerations
After surgery, consult your doctor before taking this medicine, as it may interact with anesthetics or other medications. It may also increase drowsiness.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental issues. It may also interact with sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness, so avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light exercise like walking may be fine if you feel up to it.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may affect your ability to drive or operate machinery. It is best to avoid these activities until you know how the medicine affects you. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, or if you experience severe side effects. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of antihistamines may lead to tolerance or increased side effects. Ambroxol is generally safe for short-term use. Regular monitoring of kidney and liver function may be needed if used for extended periods. Do not use for more than the recommended duration without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve nasal congestion.
Evidence: Well-establishedFlushes out allergens and thins mucus.
Evidence: Well-establishedReduces allergic triggers.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are unwell with a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage to avoid loss. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Levocetirizine starts working within 1 hour, and Ambroxol's mucolytic effect begins within 30 minutes to 1 hour. You may notice relief from sneezing and easier coughing within a few hours.
A: Do not take other antihistamines without consulting your doctor, as it may increase side effects like drowsiness.
A: Levocetirizine is considered safe (Category B), but consult your doctor before use. Ambroxol should be used only if prescribed.
🤔 Common Patient Concerns
🔄 Substitutes for lazine plus 5 mg/75 mg capsule
View AllAlternative brands with exact same active ingredient:
-
cetry plus 5mg/75mg tabletMDC Pharmaceuticals Pvt Ltd ₹35.16 1.3% CHEAPER
-
l cetron a 5 mg/75 mg capsuleAdcock Ingram Healthcare Pvt Ltd ₹37.86 6.3% COSTLIER
-
levocet plus tabletHetero Drugs Ltd ₹38.39 7.7% COSTLIER
-
betzet-am 5mg/75mg tabletSan Boston Life Sciences ₹41.00 15.1% COSTLIER
-
cetnez am 5mg/75mg tabletSitnez Biocare Pvt Ltd ₹42.19 18.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all types of cough.
Fact: It is specifically for cough associated with allergies and thick mucus. It is not effective for dry cough or cough due to infections without mucus. - Myth: It is safe to drive after taking this medicine.
Fact: This medicine can cause drowsiness. Avoid driving until you know how it affects you. - Myth: You can stop taking it as soon as you feel better.
Fact: Complete the course as prescribed by your doctor to prevent recurrence.
🔄 Alternative Options
Generic Alternatives
- Levocetirizine + Ambroxol combination tablets from other manufacturers
Brand Alternatives
- Alcast Plus 5mg/75mg Tablet SR