Barozyme Liquid: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe abdominal pain that does not go away
- Blood in vomit or stool
- Persistent vomiting or diarrhea leading to dehydration
- Signs of hyperuricemia such as joint pain or swelling
- Yellowing of the skin or eyes (jaundice)
- Decreased urine output or dark urine
If experiencing severe symptoms, call emergency services immediately.
What is krease tablet used for?
This medicine is a combination of pancreatin and dimethicone used to aid digestion and relieve bloating and gas. Pancreatin replaces missing digestive enzymes, while dimethicone helps expel trapped gas.
- Generic Name: Pancreatin (NA) + Dimethicone (NA)
- Manufacturer: TTK Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 krease tablet के बारे में (Hindi Summary)
उपयोग: यह दवा पाचन में सहायता के लिए इस्तेमाल की जाती है। इसमें पैंक्रिएटिन और डाइमेथिकोन होते हैं। पैंक्रिएटिन भोजन को पचाने में मदद करता है, जबकि डाइमेथिकोन पेट की गैस और सूजन को कम करता है। यह उन लोगों के लिए उपयोगी है जिन्हें पाचन एंजाइमों की कमी है या जो अक्सर गैस और अपच से परेशान रहते हैं।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट में असुविधा, दस्त या कब्ज शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी प्रतिक्रिया जैसे त्वचा पर चकत्ते, खुजली, चेहरे या गले में सूजन, या सांस लेने में कठिनाई हो सकती है। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक से अधिक न लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। दवा को भोजन के साथ लें। यदि आपको गाउट, किडनी की समस्या, या उच्च यूरिक एसिड है, तो डॉक्टर को बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें। ठंडी और सूखी जगह पर स्टोर करें।
💊 krease tablet Uses & Benefits
[{"condition":"Exocrine pancreatic insufficiency","description":"This medicine provides supplemental pancreatic enzymes to help digest food and absorb nutrients in conditions like chronic pancreatitis, cystic fibrosis, or after pancreatic surgery.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It helps relieve symptoms of indigestion such as bloating, fullness, and discomfort after meals by aiding digestion and reducing gas.","evidence":"Moderate"},{"condition":"Flatulence and bloating","description":"Dimethicone in this medicine reduces gas bubbles, providing relief from abdominal bloating and flatulence.","evidence":"Well-established for dimethicone"},{"condition":"Steatorrhea","description":"In pancreatic insufficiency, this medicine helps reduce fat in stools by improving fat digestion and absorption.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Post-prandial abdominal distension","description":"Sometimes used to relieve bloating after large meals, though not a primary indication.","evidence":"Limited"},{"condition":"Infant colic","description":"Dimethicone is sometimes used for infant colic, but evidence is limited and it should only be used under pediatric guidance.","evidence":"Limited"}]
Primary treatment for: Exocrine pancreatic insufficiency
Also treats: Functional dyspepsia, Flatulence, Bloating, Steatorrhea
📋 Drug Information
| Generic Name(s) | Pancreatin (NA) + Dimethicone (NA) |
| Brand Name | krease tablet |
| Manufacturer | TTK Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight. Do not freeze. Keep the container tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Pancreatin, a mixture of porcine-derived pancreatic enzymes, supplements the body's natural digestive enzymes. Amylase breaks down starches into simpler sugars, lipase breaks down fats into fatty acids and glycerol, and protease breaks down proteins into peptides and amino acids. This improves digestion and absorption of nutrients. Dimethicone is a silicone-based polymer that acts as an antifoaming agent. It reduces the surface tension of gas bubbles in the gastrointestinal tract, causing them to coalesce and be expelled more easily, thereby relieving bloating and flatulence.
Mechanism Steps
💡 How to Take krease tablet
Strength: Liquid oral preparation containing pancreatin and dimethicone. Strength not specified in the available information.
Dosage Information
| Adult Dosage | The usual adult dose is 1 to 2 teaspoons (5 to 10 mL) taken with meals or as directed by your doctor. The dose may vary depending on the condition being treated and the severity of symptoms. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may use this medicine at the same dose as adults, but should be monitored for any adverse effects. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Consult your doctor. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of krease tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Acarbose | Major | |
| Calcium carbonate antacids | Moderate | |
| Omeprazole | Moderate | |
| Ranitidine | Moderate | |
| Iron supplements | Minor |
🚨 Major Interactions
- Acarbose
- Antacids containing calcium carbonate or magnesium hydroxide
⚡ Moderate Interactions
- Proton pump inhibitors (e.g., omeprazole)
- H2 blockers (e.g., ranitidine)
🍷 Alcohol Interaction
Alcohol may worsen indigestion and increase stomach irritation. It is advisable to avoid alcohol while taking this medicine, especially if you have pancreatitis or liver disease.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to pancreatin, dimethicone, or any component of the formulation","Acute pancreatitis or acute exacerbation of chronic pancreatitis","Acute abdomen or bowel obstruction","Children with fibrosing colonopathy (for high-dose pancreatin)"]
⚠️ Warnings & Precautions
["Do not exceed the recommended dose.","Use with caution in patients with gout or hyperuricemia.","Use with caution in patients with renal impairment.","Use with caution in patients with hepatic impairment.","Consult a doctor if symptoms persist beyond 7 days.","Keep out of reach of children.","Shake well before use.","Do not use if the seal is broken."]
🤱 Lactation Safety
It is not known whether pancreatin or dimethicone pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose with this medicine is unlikely to cause serious harm due to its local action. However, if you suspect an overdose, seek medical attention immediately. Symptoms may include nausea, vomiting, diarrhea, or abdominal pain. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Shake the liquid well before each use. Measure the dose with a proper measuring device, not a household spoon. Take it with meals or snacks to help digestion. If you have a history of gout, kidney stones, or high uric acid levels, inform your doctor before using this medicine. Do not use this medicine if you are allergic to pancreatin, dimethicone, or any inactive ingredients. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children. Store in a cool, dry place, away from direct sunlight. Do not freeze. If symptoms persist or worsen, seek medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine. Monitor for any signs of allergic reaction or gastrointestinal discomfort. Dose adjustment may be needed based on kidney and liver function.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. The safety profile during pregnancy is not well established.
🏥 Post-Surgery Considerations
After surgery, consult your doctor before resuming this medicine, especially if you have had gastrointestinal surgery.
🦷 Dental Procedures
No specific precautions are needed for dental procedures. Inform your dentist about all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
No specific exercise restrictions are associated with this medicine. However, if you have abdominal discomfort, avoid strenuous activities until you feel better.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is unlikely to affect your ability to drive or operate machinery. However, if you experience dizziness or discomfort, avoid these activities until you feel well.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, especially if you have pancreatic insufficiency. If you experience severe side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when taken as prescribed. However, high doses of pancreatin have been associated with hyperuricemia and, in rare cases, fibrosing colonopathy in children with cystic fibrosis. Regular monitoring of uric acid levels may be advised. If you have kidney or liver disease, periodic check-ups are recommended. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Avoiding trigger foods and eating a balanced diet can help manage digestive symptoms.
Evidence: Well-establishedMay help improve gut health and reduce bloating, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known with this medicine. Continue routine vaccinations as per schedule.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription in case of customs checks. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, continue taking it with meals as usual; no specific time adjustment is needed. Do not leave it in a hot car or checked luggage. If you have diabetes, monitor your blood sugar more frequently as travel can affect digestion.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30 to 60 minutes after ingestion, as it aids in digesting the meal you have eaten. Symptom relief from bloating may be noticed within a few hours.
A: It may interact with certain drugs like acarbose and antacids. Always inform your doctor about all medicines you are taking.
A: Consult your doctor before use if you are pregnant or planning pregnancy. The safety is not well established.
🤔 Common Patient Concerns
🔄 Substitutes for krease tablet
View AllAlternative brands with exact same active ingredient:
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barozyme liquidBaroda Pharma Pvt Ltd ₹42.12 21.9% CHEAPER
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encarmin tabletEskag Pharma Pvt Ltd ₹45.11 16.3% CHEAPER
-
hiact p p tabletSundyota Numandis Probioceuticals Pvt Ltd ₹70.79 31.3% COSTLIER
-
hiact p tabletSundyota Numandis Probioceuticals Pvt Ltd ₹114.35 112.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure all digestive problems.
Fact: This medicine is specific for enzyme deficiency and gas-related symptoms. It does not treat infections or other causes of indigestion. - Myth: It is safe to take indefinitely without medical supervision.
Fact: Long-term use should be monitored by a doctor, especially in children and those with kidney or liver issues.
🔄 Alternative Options
Generic Alternatives
- Pancreatin + Dimethicone oral liquid (generic)
Brand Alternatives
- Barozyme Liquid