kiofiber powder - Lactitol (10gm) + Ispaghula (3.5gm) medicine

Eva Q Fiber Granules: Complete Guide to Uses, Dosage, and Safety

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🏭 Corona Remedies Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for constipation; moderate for other uses.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe abdominal pain or cramping
  • Blood in stool or rectal bleeding
  • Vomiting blood or coffee-ground vomit
  • Signs of allergic reaction: rash, itching, swelling of face, lips, or throat
  • Difficulty breathing or swallowing
  • Severe diarrhea leading to dehydration
  • No bowel movement after 3 days of use
  • Yellowing of skin or eyes (jaundice)

If experiencing severe symptoms, call emergency services immediately.

What is kiofiber powder used for?

This medicine is a combination of Lactitol and Ispaghula used to treat constipation. It works by drawing water into the intestines and adding bulk to the stool, making it easier to pass.

  • Generic Name: Lactitol (10gm) + Ispaghula (3.5gm)
  • Manufacturer: Corona Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 kiofiber powder के बारे में (Hindi Summary)

उपयोग: यह दवा लैक्टिटोल और इस्पघुला का संयोजन है, जिसका उपयोग कब्ज (कॉन्स्टिपेशन) के इलाज के लिए किया जाता है। यह मल को नरम करती है और आंतों की गति को बढ़ाती है, जिससे मल त्याग में आसानी होती है। इसका उपयोग इरिटेबल बाउल सिंड्रोम और हेपेटिक एन्सेफेलोपैथी में भी किया जाता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में पेट फूलना, गैस, पेट में ऐंठन और जी मिचलाना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ दिनों में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन तेज पेट दर्द, मल में खून आना, या एलर्जी की प्रतिक्रिया हो सकती है। ऐसा होने पर तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे हमेशा भरपूर पानी के साथ लें। सूखा न लें, क्योंकि इससे गले में रुकावट हो सकती है। अन्य दवाओं के साथ लेने से पहले 2 घंटे का अंतराल रखें। यदि आपको मधुमेह है, तो ब्लड शुगर की निगरानी करें। 2 सप्ताह से अधिक उपयोग करने से पहले डॉक्टर से सलाह लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से परामर्श करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 kiofiber powder Uses & Benefits

[{"condition":"Chronic constipation","description":"This medicine helps relieve chronic constipation by softening stools and promoting bowel movements through osmotic and bulk-forming actions.","evidence":"Well-established"},{"condition":"Irritable bowel syndrome with constipation (IBS-C)","description":"It helps regulate bowel habits and reduce straining in patients with IBS-C.","evidence":"Moderate"},{"condition":"Hepatic encephalopathy","description":"Lactitol helps reduce blood ammonia levels by acidifying the colon and promoting ammonia excretion, useful in hepatic encephalopathy.","evidence":"Well-established for lactitol component"},{"condition":"Post-operative constipation","description":"Used to prevent or treat constipation after surgery when straining should be avoided.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of constipation in bedridden patients","description":"Sometimes used off-label to prevent constipation in immobile patients.","evidence":"Limited"},{"condition":"Opioid-induced constipation","description":"May be used off-label to manage constipation caused by opioid pain medications.","evidence":"Limited"}]

Primary treatment for: Constipation

Also treats: Irritable bowel syndrome with constipation, Hepatic encephalopathy, Post-operative constipation

📋 Drug Information

Generic Name(s)Lactitol (10gm) + Ispaghula (3.5gm)
Brand Namekiofiber powder
ManufacturerCorona Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place. Protect from moisture and direct sunlight. Keep the container tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always mix this medicine with a full glass of water and drink immediately to prevent choking.
2
Take this medicine at bedtime for best results, as it works overnight.
3
Increase your water intake throughout the day while taking this medicine.
4
If you are taking other medications, take them at least 2 hours before or after this medicine.
5
Do not use this medicine for more than 2 weeks without consulting your doctor.
6
If you have diabetes, monitor your blood sugar levels regularly as lactitol may affect them.
7
Report any severe abdominal pain, rectal bleeding, or allergic reactions immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Constipation
This medicine is commonly prescribed for this.
Likely Use
✅
Irregular bowel movements
This medicine helps regulate bowel movements.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionLactitol is minimally absorbed from the gastrointestinal tract; most of it reaches the colon intact. Ispaghula is not absorbed systemically as it is a fiber; it acts locally in the gut.
DistributionSince lactitol is poorly absorbed, its distribution is primarily limited to the gastrointestinal tract. Ispaghula remains in the gut lumen and is not distributed systemically.
Protein BindingNot established from the available information.
MetabolismLactitol is metabolized by colonic bacteria into short-chain fatty acids, carbon dioxide, and methane. Ispaghula is fermented by colonic bacteria to some extent, but mostly excreted in feces.
Half-LifeNot applicable, as this medicine acts locally in the gut and is not absorbed systemically.
ExcretionLactitol and its metabolites are primarily excreted in feces. Ispaghula is excreted in feces as undigested fiber.
BioavailabilityLactitol has negligible systemic bioavailability. Ispaghula is not systemically bioavailable.
Onset of ActionThe onset of action for lactitol is typically 24 to 48 hours, while ispaghula may take 12 to 72 hours to produce a bowel movement. The combination may work within 24 to 48 hours.
Peak Plasma TimeNot applicable, as this medicine is not absorbed into the bloodstream.
Duration of ActionThe effects last until the next bowel movement, typically within 24 to 48 hours after administration.

How It Works

This medicine combines two laxatives with complementary mechanisms. Lactitol is a disaccharide sugar alcohol that is poorly absorbed in the small intestine. It reaches the colon unchanged, where it is metabolized by colonic bacteria into short-chain fatty acids. This process lowers the colonic pH, which stimulates peristalsis and draws water into the colon osmotically, softening the stool. Ispaghula is a soluble fiber that absorbs water to form a gel-like mass. This increases stool bulk, which stimulates intestinal motility and reduces transit time. Together, they effectively relieve constipation by both softening the stool and adding bulk to promote bowel movements.

Mechanism Steps

1
Osmotic action of lactitol: Lactitol remains undigested in the small intestine and reaches the colon, where it draws water osmotically into the intestinal lumen, softening the stool.
2
Fermentation by colonic bacteria: Colonic bacteria ferment lactitol into short-chain fatty acids, lowering colonic pH and stimulating peristalsis.
3
Bulk-forming action of ispaghula: Ispaghula absorbs water to form a gel, increasing stool bulk and moisture, which promotes bowel movements.
4
Stimulation of peristalsis: The increased bulk and water content stimulate the intestinal walls, enhancing peristaltic movements and facilitating stool passage.

💡 How to Take kiofiber powder

Strength: Granules: Lactitol 10 gm + Ispaghula 3.5 gm per sachet.

1Empty one sachet of granules into a glass.
2Add about 150-200 ml of water or juice.
3Stir well until granules are dispersed.
4Drink immediately.
5Follow with another glass of water to ensure complete ingestion.
6Take at bedtime for best results.

Dosage Information

Adult DosageThe usual adult dose is 1 to 2 sachets (each containing Lactitol 10 gm and Ispaghula 3.5 gm) per day, preferably at bedtime. The dose may be adjusted by your doctor based on your condition and response. Mix the granules in a glass of water or juice, stir well, and drink immediately. Follow with another glass of water. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of laxatives. Start with a lower dose and monitor for dehydration and electrolyte imbalance. Consult a doctor for appropriate dosing.
Renal ImpairmentNo specific dose adjustment is established. Use with caution in renal impairment due to risk of electrolyte imbalance. Consult a doctor.
Hepatic ImpairmentNo specific dose adjustment is established. Lactitol is used in hepatic encephalopathy; dose may be adjusted based on ammonia levels. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is 2 sachets (Lactitol 20 gm + Ispaghula 7 gm). Do not exceed without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With water
Take with a full glass of water
Essential for proper action and to prevent choking.
With food
Can be taken with or without food
Food does not significantly affect its action.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of kiofiber powder

✅ Common Side Effects

Bloating (Common (5-10%))
Usually resolves as your body adjusts. If persistent, consult your doctor.
Flatulence (Common (5-10%))
May decrease over time. Avoid carbonated drinks to reduce gas.
Abdominal cramps (Common (5-10%))
Take with plenty of water. If severe, contact your doctor.
Nausea (Uncommon (1-5%))
Take with food or milk to reduce nausea.

🚨 Serious Side Effects

Severe abdominal pain (Rare (<0.1%))
Seek immediate medical attention.
Rectal bleeding (Rare (<0.1%))
Consult a doctor immediately.
Allergic reaction (rash, itching, swelling) (Rare (<0.1%))
Discontinue and seek emergency care if swelling of face or throat occurs.
Electrolyte imbalance (Rare (<0.1%))
Monitor if prolonged use; consult doctor for blood tests.

⚠️ Rare Side Effects

Intestinal obstruction
Seek emergency medical attention if you experience severe abdominal pain, vomiting, and inability to pass stool.
Esophageal blockage
Always take with a full glass of water. If you feel chest pain or difficulty swallowing, seek immediate care.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Digoxin Major
Lithium Major
Antidiabetics Moderate
Diuretics Moderate
Corticosteroids Moderate
Thyroid hormones Minor
Iron supplements Minor
Tetracycline antibiotics Moderate
Carbamazepine Moderate

🚨 Major Interactions

  • Oral medications (general)
  • Warfarin
  • Digoxin
  • Lithium

⚡ Moderate Interactions

  • Antidiabetic drugs
  • Diuretics
  • Corticosteroids

🍷 Alcohol Interaction

Alcohol may worsen dehydration and electrolyte imbalance caused by this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to lactitol, ispaghula, or any component","Intestinal obstruction or perforation","Severe inflammatory bowel disease (e.g., Crohn's disease, ulcerative colitis)","Undiagnosed abdominal pain or rectal bleeding","Galactosemia (lactitol contains galactose)","Children under 12 years (unless prescribed)"]

⚠️ Warnings & Precautions

["Do not take this medicine dry; always mix with water or take with a full glass of water to avoid choking.","If you have diabetes, monitor blood sugar as lactitol may affect levels.","Avoid taking other medications within 2 hours of this medicine.","Do not use for more than 2 weeks without medical advice.","If constipation persists despite use, consult a doctor.","In elderly or debilitated patients, monitor for dehydration and electrolyte imbalance.","Use with caution in patients with renal impairment.","Use with caution in patients with swallowing difficulties."]

🤱 Lactation Safety

It is not known if lactitol or ispaghula pass into breast milk. However, they are not systemically absorbed, so risk to the infant is likely low. Consult your doctor before use.

💊 Overdose Management

Overdose may cause severe diarrhea, abdominal cramps, and electrolyte imbalance. Treatment is symptomatic and supportive. Ensure adequate hydration. If overdose is suspected, contact a poison control center or seek emergency medical attention immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Drink plenty of water throughout the day while taking this medicine, as it works best when you are well hydrated. Take this medicine with a full glass of water. Do not take it dry, as it can cause choking or blockages. If you have diabetes, monitor your blood sugar levels, as lactitol may affect them. Avoid taking this medicine within 2 hours of other medications, as it may interfere with their absorption. Do not use this medicine for more than 2 weeks without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before taking this medicine. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to dehydration and electrolyte imbalance. Monitor fluid intake and electrolytes. Use the lowest effective dose.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe, but medical advice is recommended.

🏥 Post-Surgery Considerations

This medicine may be used post-surgery to prevent constipation when straining should be avoided. Consult your surgeon for specific instructions.

🦷 Dental Procedures

No specific precautions. Inform your dentist if you are taking this medicine.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water throughout the day.
🥗
Include fiber-rich foods in your diet.
😴
Exercise regularly to promote bowel movements.
💧
Establish a regular toilet routine.
🧘
Avoid delaying bowel movements when you feel the urge.

🏋️ Exercise Considerations

No specific exercise restrictions. However, if you experience dizziness or dehydration, avoid strenuous exercise until you feel better.

🥗 Diet Recommendations

Increase intake of fruits and vegetables.
Choose whole grains over refined grains.
Stay well hydrated.
Limit processed foods and red meat.
Include probiotics like yogurt.

💼 Impact on Daily Work & Life

This medicine may cause bloating or abdominal cramps, which could affect your comfort at work. However, it does not usually impair driving or operating machinery. Stay hydrated to minimize side effects.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if you experience severe abdominal pain, rectal bleeding, or allergic reactions. Do not stop abruptly if you have been on it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to electrolyte imbalances, dependence on laxatives, and reduced natural bowel function. It should be used for short periods unless prescribed by a doctor. Regular monitoring of electrolytes and bowel habits is advised.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Dietary fiber

Increasing dietary fiber can help relieve constipation naturally.

Evidence: Well-established
Probiotics

Probiotics may improve gut health and bowel regularity.

Evidence: Moderate
Biofeedback

For chronic constipation, biofeedback therapy can help retrain pelvic floor muscles.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, continue taking it at your usual bedtime. Ensure you have enough supply for your trip. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 50-year-old woman with chronic constipation
She had been struggling with constipation for years. Her doctor prescribed this medicine. She started taking one sachet at bedtime with plenty of water. After 2 days, she noticed softer stools and easier bowel movements. She also increased her water intake and added more fiber to her diet. She experienced mild bloating initially, which subsided after a week.
💡 Lesson: Consistency and adequate hydration are key to getting the best results from this medicine.
👤 A 65-year-old man with hepatic encephalopathy
He was prescribed this medicine to help reduce ammonia levels. He took it as directed, and his doctor monitored his ammonia levels regularly. He experienced some gas and bloating but found it manageable. His mental alertness improved over time.
💡 Lesson: This medicine can be beneficial for hepatic encephalopathy, but regular monitoring is essential.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually takes 24 to 48 hours to produce a bowel movement. However, it may take longer for some individuals.

Q: Can I take it every day?

A: It can be taken daily for short periods, but prolonged use should be under medical supervision.

Q: Is it safe during pregnancy?

A: Consult your doctor before use. It is generally considered safe when used as directed, but medical advice is recommended.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for kiofiber powder

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is habit-forming.
    Fact: This medicine is not habit-forming when used as directed. However, prolonged use without medical supervision is not recommended.
  • Myth: It can be taken without water.
    Fact: It must be taken with plenty of water to prevent choking and ensure effectiveness.
  • Myth: It works immediately.
    Fact: It may take 24 to 48 hours to produce a bowel movement.

🔄 Alternative Options

Generic Alternatives

  • Lactitol + Ispaghula granules (various manufacturers)

Brand Alternatives

  • Eva Q Fiber Granules

📊 Comparison with Similar Medicines

[{"medicine":"Eva Q Fiber Granules","active_ingredient":"Lactitol + Ispaghula","onset":"24-48 hours","route":"Oral"},{"medicine":"Lactulose","active_ingredient":"Lactulose","onset":"24-48 hours","route":"Oral"},{"medicine":"Psyllium husk","active_ingredient":"Ispaghula","onset":"12-72 hours","route":"Oral"}]

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