Ketolice Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is ketoskip tablet used for?
This medicine is a combination of ketoprofen (an NSAID) and thiocolchicoside (a muscle relaxant) used for short-term relief of acute musculoskeletal pain and muscle spasm. It is taken orally with food, usually one tablet once or twice daily, for up to 7 days.
- Generic Name: Ketoprofen (50mg) + Thiocolchicoside (4mg)
- Manufacturer: Skiptuit Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ketoskip tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कीटोप्रोफेन और थायोकोल्चिकोसाइड का संयोजन है, जिसका उपयोग तीव्र मस्कुलोस्केलेटल दर्द और मांसपेशियों की ऐंठन के अल्पकालिक उपचार के लिए किया जाता है। यह दर्द, सूजन और ऐंठन को कम करने में मदद करती है। इसे भोजन के साथ मुँह से लिया जाता है।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, अपच, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, गुर्दे की समस्या, यकृत की समस्या, गंभीर एलर्जी प्रतिक्रिया और हृदय संबंधी घटनाएं शामिल हैं। यदि आपको काला या खूनी मल, खून की उल्टी, गंभीर पेट दर्द, सीने में दर्द, सांस लेने में कठिनाई, चेहरे या गले में सूजन, आंखों या त्वचा का पीलापन, या पेशाब में कमी दिखे तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। पेट की परेशानी कम करने के लिए इसे भोजन या दूध के साथ लें। शराब से बचें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ जाता है। यदि आपको चक्कर आते हैं या नींद आती है तो वाहन न चलाएं या भारी मशीनरी न चलाएं। यदि आपको पेट के अल्सर, गुर्दे या यकृत की बीमारी, हृदय की समस्या, या अस्थमा का इतिहास है तो अपने डॉक्टर को बताएं। गर्भावस्था, गर्भावस्था की योजना, या स्तनपान के दौरान इस दवा का उपयोग करने से पहले अपने डॉक्टर से बात करें। बच्चों की पहुंच से दूर रखें।
💊 ketoskip tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain with muscle spasm","description":"Relieves pain and inflammation while reducing muscle spasm in conditions like back pain, neck pain, and sprains.","evidence":"Well-established"},{"condition":"Low back pain","description":"Short-term relief of acute low back pain associated with muscle spasm.","evidence":"Well-established"},{"condition":"Post-traumatic pain","description":"Used for pain and swelling after soft tissue injuries such as sprains and strains.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Tension-type headache","description":"Sometimes used off-label for tension headaches with muscle tightness, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Acute musculoskeletal pain with muscle spasm
Also treats: Low back pain, Neck pain, Sprains and strains, Post-traumatic pain
📋 Drug Information
| Generic Name(s) | Ketoprofen (50mg) + Thiocolchicoside (4mg) |
| Brand Name | ketoskip tablet |
| Manufacturer | Skiptuit Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ketoprofen inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis and thereby decreasing inflammation, pain, and fever. Thiocolchicoside acts as a centrally acting muscle relaxant by binding to GABA-A receptors and strychnine-sensitive glycine receptors in the spinal cord and brainstem, reducing muscle tone and spasm.
Mechanism Steps
💡 How to Take ketoskip tablet
Strength: Each immediate-release tablet contains ketoprofen 50 mg and thiocolchicoside 4 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally one to two times daily, preferably with food. The exact dose and duration depend on the condition being treated and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose reduction may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose of ketoprofen is 200 mg, but for this combination, the maximum daily dose is typically 2 tablets (100 mg ketoprofen and 8 mg thiocolchicoside). Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ketoskip tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aspirin | Major | |
| Ibuprofen | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Corticosteroids | Major | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., aspirin, ibuprofen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- ACE inhibitors and ARBs
- Diuretics
- SSRIs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of stomach bleeding, ulcers, and liver problems. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney disease","Severe liver disease","Asthma triggered by aspirin or other NSAIDs","Third trimester of pregnancy","Breastfeeding","Known allergy to ketoprofen, thiocolchicoside, or any component","Children under 18 years (safety not established)"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol and other NSAIDs.","Use with caution in the elderly due to increased risk of side effects.","Do not drive or operate machinery if you feel dizzy or drowsy.","Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma.","Do not use for more than 7 days without medical advice.","Stop and consult a doctor if you experience signs of bleeding, allergic reaction, or severe abdominal pain."]
🤱 Lactation Safety
Not established from the available information. Ketoprofen may pass into breast milk and could cause adverse effects in the infant. Thiocolchicoside is not recommended during breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose may cause severe nausea, vomiting, abdominal pain, drowsiness, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be considered if within 1-2 hours of ingestion. Monitor vital signs and electrolytes.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach upset. Avoid alcohol because it increases the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Do not take other NSAIDs or pain relievers without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney injury, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly. Avoid concurrent use of other NSAIDs or anticoagulants.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester, due to risk of premature closure of ductus arteriosus and kidney problems in the fetus. If you are planning pregnancy, consult your doctor for safer alternatives for pain relief.
🏥 Post-Surgery Considerations
This medicine may be used for post-surgical pain and inflammation, but it can increase the risk of bleeding. Consult your surgeon before taking this medicine after surgery, especially if you are on blood thinners or have a bleeding disorder.
🦷 Dental Procedures
This medicine can increase the risk of bleeding during dental procedures. Inform your dentist that you are taking this medicine before any dental work. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may worsen pain while taking this medicine. Gentle stretching and low-impact activities may be beneficial, but consult your doctor or physiotherapist before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food. Inform your employer if your job involves operating heavy machinery.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe abdominal pain, black or bloody stools, vomiting blood, signs of allergic reaction (rash, swelling, difficulty breathing), yellowing of skin or eyes, decreased urine output, or if your pain does not improve within 7 days. Do not stop abruptly if you have been on long-term therapy without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to increased risk of gastrointestinal bleeding, kidney injury, liver problems, and cardiovascular events. If long-term use is necessary, regular monitoring of kidney and liver function, blood counts, and blood pressure is required. Consult your doctor for alternative treatments if pain persists beyond 7 days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve muscle strength and flexibility.
Evidence: Well-establishedApplying heat or cold packs can help relieve muscle spasm and pain.
Evidence: ModerateMay help reduce pain in some individuals, but evidence is mixed.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for controlled substances; this medicine is generally not controlled but carry documentation. Keep enough supply for your trip and avoid packing in checked luggage to prevent loss.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief typically begins within 30 to 60 minutes after taking the tablet. Muscle relaxant effects may take a few hours to become noticeable.
A: No, it should be taken with food or milk to reduce the risk of stomach upset and bleeding.
A: Do not take other NSAIDs or pain relievers without consulting your doctor, as it may increase the risk of side effects.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is not recommended during the third trimester of pregnancy and should be avoided during breastfeeding. Consult your doctor for safer alternatives.
🤔 Common Patient Concerns
🔄 Substitutes for ketoskip tablet
View AllAlternative brands with exact same active ingredient:
-
ketolice tabletAlicia Healthcare ₹182.81 8.3% COSTLIER
-
spifen mr 50mg/4mg tabletFawn Incorporation ₹187.41 11.1% COSTLIER
-
ketonid mr 50mg/4mg tabletWerke Healthcare ₹205.00 21.5% COSTLIER
-
lupiflex 4 tabletLupin Ltd ₹211.59 25.4% COSTLIER
-
ketomex th 50mg/4mg tabletTNT Lifesciences ₹263.44 56.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects and should be avoided unless specifically prescribed by a doctor. - Myth: It is safe to take this medicine on an empty stomach.
Fact: Taking this medicine with food reduces the risk of stomach upset and bleeding. It should always be taken with meals. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is not recommended during the third trimester of pregnancy and should be avoided during breastfeeding. Consult your doctor for safer alternatives.
🔄 Alternative Options
Generic Alternatives
- Ketoprofen 50 mg + Thiocolchicoside 4 mg tablet (generic)
Brand Alternatives
- Ketolice Tablet