Ketofen 50mg Tablet: Complete Guide To Uses, Dosage, Side Effects, And Safety

[{"condition":"Osteoarthritis","description":"This medicine reduces joint pain, stiffness, and inflammation" class="semantic-link" title="Medicines for swelling">swelling in osteoarthritis of the knee, hip, hand, and spine, helping people move more comfortably.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"It provides symptomatic relief of pain and inflammation in rheumatoid arthritis and is often used alongside disease-modifying antirheumatic drugs.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"This medicine helps relieve back and joint pain and morning stiffness associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute gout","description":"It can reduce the severe joint pain and swelling of an acute gout attack when used early in the flare.","evidence":"Well-established"},{"condition":"Soft tissue injuries","description":"This medicine is used for short-term relief of pain and swelling after sprains, strains, and sports injuries.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"It may be prescribed for short-term pain relief after minor surgical or dental procedures.","evidence":"Moderate"},{"condition":"Primary dysmenorrhea","description":"This medicine can ease menstrual cramps by lowering prostaglandin levels in the uterus.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine attacks","description":"Some clinicians use this medicine off-label for acute migraine pain, but it is not a first-line choice.","evidence":"Limited"},{"condition":"Pericarditis pain","description":"It has been used off-label as part of anti-inflammatory therapy for pericarditis in selected patients.","evidence":"Limited"}]

Primary treatment for: Inflammatory and painful musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, and soft tissue injuries

Also treats: Ankylosing spondylitis, Acute gout, Primary dysmenorrhea, Postoperative pain, Dental pain

Generic Name(s)	Ketoprofen (50mg)
Brand Name	ketofen 50mg tablet
Manufacturer	PCI Pharmaceuticals
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)
Route of Administration	Oral
Storage	Store this medicine at room temperature between 15°C and 30°C, away from direct sunlight, heat, and moisture. Keep the tablets in their original blister pack or container with the lid tightly closed. Do not store in the bathroom or near the kitchen sink. Keep out of reach of children and pets.
Shelf Life	The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the manufacturer's packaging. Always check the expiry date printed on the pack and do not use the tablets after that date.
WHO Guideline	Not established from the available information. Ketoprofen is not specifically named in current WHO essential medicines guidance for pain, which generally lists other NSAIDs such as ibuprofen and naproxen.
ICMR Guideline	Not established from the available information. Indian guidelines generally recommend using NSAIDs at the lowest effective dose for the shortest duration for musculoskeletal pain, with caution in kidney, heart, and stomach disease.

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

Drug	Severity	Effect
Warfarin	Major
Aspirin	Major
Prednisolone	Major
Lisinopril	Major
Lithium	Major
Methotrexate	Major
Sertraline	Moderate
Furosemide	Moderate
Digoxin	Moderate
Cyclosporine	Moderate

🚫 Contraindications

["Active or history of stomach or intestinal ulcer or bleeding","Severe heart failure or recent heart attack","Severe kidney disease or kidney failure","Severe liver disease or active liver injury","Known allergy to Ketoprofen or other NSAIDs","History of asthma, hives, or allergic reaction after taking aspirin or another NSAID","Third trimester of pregnancy","Children under 15 years of age unless specifically prescribed by a pediatrician","Use before or during coronary artery bypass graft surgery"]

⚠️ Warnings & Precautions

["Take this medicine with food or milk to reduce stomach irritation.","Do not use this medicine for more than 10 days without medical advice.","Avoid alcohol and other NSAIDs while taking this medicine.","Tell your doctor if you have heart disease, high blood pressure, kidney disease, liver disease, or diabetes.","Use with caution in elderly patients, who are at higher risk of stomach bleeding and kidney problems.","Do not drive or operate machinery if you feel dizzy or drowsy.","Stop the medicine and seek medical help if you notice signs of bleeding, allergic reaction, or severe stomach pain.","Inform your doctor about all other medicines, supplements, and herbal products you take.","Do not take this medicine if you are dehydrated or have severe vomiting or diarrhea.","Use the lowest effective dose for the shortest duration that controls your symptoms."]

🤱 Lactation Safety

Ketoprofen passes into breast milk in small amounts. Short-term use of a single dose is generally considered acceptable, but repeated or high-dose use is not recommended while breastfeeding because of possible effects on the baby's stomach, kidneys, and bleeding risk. Consult your doctor or a lactation specialist before using this medicine while nursing.

Additional Safety Advice

If you are trying to conceive, discuss this medicine with your doctor before use. NSAIDs like this medicine may interfere with ovulation and are generally not recommended around the time of conception or in early pregnancy unless clearly needed. In the third trimester, this medicine should be avoided because it can cause premature closure of the ductus arteriosus in the baby and reduce amniotic fluid. Your doctor can suggest safer alternatives for pain relief if you are planning pregnancy or are already pregnant.

This medicine may be used for short-term pain relief after some surgical procedures, but it is contraindicated around coronary artery bypass graft surgery because of increased heart risk. After surgery, your doctor will decide whether this medicine is safe for you based on your kidney function, bleeding risk, and other medicines you are taking. Do not start this medicine on your own after surgery. Follow your surgeon's instructions for pain relief and wound care.

This medicine can be used for short-term pain relief after dental procedures such as tooth extraction or root canal treatment. However, it can increase bleeding risk, so inform your dentist if you are taking this medicine or blood thinners before any dental work. Your dentist may advise you to stop the medicine for a short period before the procedure or may choose a different pain reliever. Do not stop or change your medicine without consulting your doctor or dentist.

While taking this medicine, you may feel less pain and be tempted to do more activity than usual. Increase your activity gradually to avoid injury. Avoid high-impact exercises that strain your joints, especially if you have arthritis. If you feel dizzy or drowsy, avoid exercises that require balance or coordination. Stay well hydrated during exercise because dehydration increases the risk of kidney problems with this medicine. Consult your doctor or physiotherapist before starting a new exercise program.

This medicine may cause dizziness or drowsiness in some people, which can affect your ability to drive or operate heavy machinery. Avoid driving or using machinery until you know how the medicine affects you. If your work involves physical strain, take breaks and avoid lifting heavy objects, especially if you have back or joint pain. Inform your employer about any work restrictions advised by your doctor. Most people can continue their normal daily activities while taking this medicine, but listen to your body and rest when needed.

Stop taking this medicine and contact your doctor immediately if you develop signs of stomach bleeding such as black stools or vomiting blood, severe stomach pain, signs of an allergic reaction such as swelling of the face or difficulty breathing, yellowing of the skin or eyes, decreased urine output, or chest pain. Do not stop this medicine suddenly if you have been taking it for a long time without consulting your doctor, because your pain may return. Your doctor will advise you on the best way to stop or switch to another medicine.

Long-term use of this medicine can increase the risk of stomach ulcers and bleeding, kidney injury, high blood pressure, heart attack, and stroke. It may also worsen heart failure and cause fluid retention. Regular monitoring of blood pressure, kidney function, liver function, and blood counts is recommended during long-term therapy. Your doctor may also consider a stomach-protecting medicine. Long-term use should be reviewed regularly, and the medicine should be stopped or changed if side effects develop or if safer alternatives are available.

🔄 Substitutes for ketofen 50mg tablet

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[{"medicine":"Ketoprofen 50mg","class":"NSAID","usual_dose":"50mg two to three times a day","onset":"30 to 60 minutes","duration":"4 to 6 hours","main_risk":"Stomach bleeding, kidney and heart risk"},{"medicine":"Ibuprofen 400mg","class":"NSAID","usual_dose":"400mg three times a day","onset":"30 to 60 minutes","duration":"4 to 6 hours","main_risk":"Stomach upset, kidney and heart risk"},{"medicine":"Naproxen 250mg","class":"NSAID","usual_dose":"250mg two to three times a day","onset":"1 hour","duration":"8 to 12 hours","main_risk":"Stomach bleeding, kidney and heart risk"},{"medicine":"Paracetamol 500mg","class":"Analgesic and antipyretic","usual_dose":"500mg to 1000mg up to four times a day","onset":"30 to 60 minutes","duration":"4 to 6 hours","main_risk":"Liver injury in overdose"}]