Encrozep Plus Ointment: A Topical Solution for Neuropathic Pain
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe burning, blistering, or peeling of the skin at the application site.
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Signs of an allergic reaction such as a widespread rash or hives.
- Dizziness, drowsiness, or confusion that does not go away.
- Pain that worsens or does not improve after several weeks of use.
- New or unusual symptoms such as muscle weakness or difficulty walking.
If experiencing severe symptoms, call emergency services immediately.
What is ketogab ointment used for?
This medicine is a topical ointment containing gabapentin and capsaicin-based rubefacients. It is used to relieve localized neuropathic pain by reducing abnormal nerve firing and desensitizing pain nerve endings. Apply it thinly to the affected skin as directed by your doctor.
- Generic Name: Gabapentin (8% w/w) + Capsaicin Based Rubefacients (0.035% w/w)
- Manufacturer: Sanador Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ketogab ointment के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल ऑइंटमेंट है जिसमें गैबापेंटिन और कैप्साइसिन आधारित रूबेफेशिएंट्स होते हैं। इसका उपयोग त्वचा पर लगाकर स्थानीय न्यूरोपैथिक दर्द को कम करने के लिए किया जाता है, जैसे कि डायबिटिक न्यूरोपैथी या दाद के बाद होने वाला दर्द। यह दर्द को कम करने और जलन को शांत करने में मदद करता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में लगाने की जगह पर हल्की जलन, लालिमा, खुजली या सूखापन शामिल हैं। ये आमतौर पर अस्थायी होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर त्वचा पर छाले पड़ें, सूजन हो या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को केवल प्रभावित त्वचा पर ही लगाएं। आंखों, मुंह और नाक से दूर रखें। टूटी या घायल त्वचा पर न लगाएं। उपयोग से पहले और बाद में हाथ धोएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 ketogab ointment Uses & Benefits
[{"condition":"Diabetic peripheral neuropathy","description":"This medicine is applied topically to relieve burning, shooting, or stabbing pain in the feet and hands caused by nerve damage from diabetes.","evidence":"Moderate"},{"condition":"Post-herpetic neuralgia","description":"It helps reduce persistent nerve pain that remains after a shingles rash has healed.","evidence":"Moderate"},{"condition":"Localized neuropathic pain","description":"Used for various types of localized nerve pain, such as that following surgery or trauma.","evidence":"Limited"}]
Off-label uses: [{"condition":"Osteoarthritis pain","description":"Sometimes applied topically to provide additional pain relief in osteoarthritis, though evidence is limited.","evidence":"Limited"},{"condition":"Musculoskeletal pain","description":"May be used off-label for localized muscle or joint pain, but its role is not well established.","evidence":"Limited"}]
Primary treatment for: Neuropathic pain
Also treats: Diabetic peripheral neuropathy, Post-herpetic neuralgia
📋 Drug Information
| Generic Name(s) | Gabapentin (8% w/w) + Capsaicin Based Rubefacients (0.035% w/w) |
| Brand Name | ketogab ointment |
| Manufacturer | Sanador Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Keep away from direct sunlight and moisture. Do not freeze. |
| Shelf Life | Not established from the available information. Check the packaging for the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works through two complementary mechanisms. Gabapentin, the primary active ingredient, is thought to bind to the alpha-2-delta subunit of voltage-gated calcium channels on nerve cells. This action reduces the release of excitatory neurotransmitters and decreases abnormal nerve firing that contributes to neuropathic pain. Capsaicin, a component of the rubefacients, interacts with TRPV1 receptors on sensory nerve endings. Initially it causes a warming or burning sensation, but with repeated application it desensitizes these nerve endings, leading to reduced pain transmission. The rubefacient effect also increases local blood flow, which may help distribute the active ingredients and provide a soothing sensation.
Mechanism Steps
💡 How to Take ketogab ointment
Strength: Ointment containing Gabapentin 8% w/w and Capsaicin-based rubefacients 0.035% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area of skin as directed by your doctor. The frequency and duration of use depend on the condition being treated and your response to therapy. Typically, it may be applied 2 to 4 times daily, but the exact dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended application frequency. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may use this medicine as directed by a doctor. No specific dose adjustment is typically required for topical use, but caution is advised due to potentially increased skin sensitivity. |
| Renal Impairment | No dose adjustment is typically required for topical use, as systemic absorption is minimal. However, consult your doctor if you have severe kidney disease. |
| Hepatic Impairment | No dose adjustment is typically required for topical use, as systemic absorption is minimal. However, consult your doctor if you have severe liver disease. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information. Follow your doctor's instructions and do not exceed the recommended application frequency. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ketogab ointment
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to gabapentin, capsaicin, or any component of this medicine.","Application to broken or irritated skin.","Use in eyes or mucous membranes."]
⚠️ Warnings & Precautions
["For external use only. Do not swallow.","Avoid contact with eyes, mouth, and other mucous membranes.","Do not apply to large areas of skin without medical advice.","Do not use with occlusive dressings or heating pads unless instructed.","Keep out of reach of children.","Consult a doctor if pain persists or worsens.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]
🤱 Lactation Safety
Not established from the available information. It is not known whether this medicine passes into breast milk. Consult your doctor before use while breastfeeding. Avoid applying to the breast area.
💊 Overdose Management
Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of gabapentin overdose may include dizziness, drowsiness, blurred vision, and difficulty breathing. Contact a poison control center or emergency room right away.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
Apply this medicine only to the affected area of skin as directed by your doctor. Wash your hands thoroughly before and after applying the ointment, unless your hands are the treated area. Avoid contact with eyes, mouth, nose, and other mucous membranes. Do not apply to cuts, wounds, or irritated skin. Do not cover the treated area with a tight bandage or heating pad unless instructed. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Do not use more than the recommended amount or more often than prescribed. If your pain does not improve or worsens after a few weeks, contact your healthcare provider.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have more sensitive skin and are more prone to skin reactions. Use this medicine with caution and monitor for any signs of irritation. No specific dose adjustment is typically required for topical use, but consult your doctor if you have other health conditions.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. There is limited information on the safety of topical gabapentin and capsaicin during pregnancy. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before applying this medicine to the surgical area. It should not be applied to healing wounds or incisions unless specifically instructed.
🦷 Dental Procedures
This medicine is applied to the skin and is not expected to interfere with dental procedures. However, inform your dentist about all medications you are taking, including topical ones.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While using this medicine, you can generally continue your regular exercise routine. However, if you experience dizziness or drowsiness, avoid activities that require alertness, such as driving or operating heavy machinery. If you have neuropathy, choose low-impact exercises to prevent injury to your feet.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to work. However, if you experience dizziness or drowsiness, avoid driving or operating machinery until you know how the medicine affects you. You can apply it at home before work or as needed during the day, but ensure you wash your hands after application to avoid transferring it to others or to your eyes.
🛑 When to Stop This Medicine
Do not stop using this medicine without consulting your doctor. If your pain improves, your doctor may adjust the frequency or discontinue it. If you experience severe side effects or an allergic reaction, stop using it and seek medical attention immediately. If your pain does not improve after several weeks, consult your doctor for alternative treatments.
📅 Long-Term Use Effects
Long-term use of this medicine is generally considered safe for topical application, but prolonged use may lead to skin dryness, irritation, or sensitivity. There is no established information on systemic long-term effects from topical gabapentin. It is advisable to have periodic reviews with your doctor to assess the continued need for treatment and to monitor for any skin changes.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help improve strength, flexibility, and reduce pain for certain neuropathic conditions.
Evidence: ModerateMay provide temporary relief for localized nerve pain.
Evidence: LimitedOral gabapentinoids or antidepressants may be prescribed for more widespread neuropathic pain.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, inform your healthcare provider about all medicines you are using before any vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C).
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight.
❌ DON'T
Do not store in the bathroom cabinet.
✈️ Traveling with This Medicine
When traveling with this medicine, keep it in its original packaging with the prescription label intact. Carry a copy of your prescription in case you need to show it at customs or security. Store it at room temperature and protect it from extreme heat or cold. If you are flying, pack it in your carry-on luggage to avoid temperature fluctuations in checked baggage. There are no specific time zone adjustments needed for topical application, but try to maintain your regular application schedule as closely as possible.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some people may notice a warming sensation immediately, but noticeable pain relief may take several days to weeks of regular use. It is important to apply it consistently as directed.
A: No, this medicine should not be applied to the face or near the eyes, mouth, or mucous membranes unless specifically instructed by your doctor.
A: If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose.
A: Generally, topical application has minimal systemic absorption, so interactions are unlikely. However, inform your doctor about all medications you are taking to be safe.
🤔 Common Patient Concerns
🔄 Substitutes for ketogab ointment
View AllAlternative brands with exact same active ingredient:
-
encrozep plus ointmentMascot Health Series Pvt Ltd ₹234.38 12.2% CHEAPER
-
myolin-kt ointmentSolarium Pharmaceuticals ₹242.81 9.1% CHEAPER
-
gabatrix ointmentEsmatrix Life Sciences Pvt Ltd ₹328.13 22.9% COSTLIER
-
shri senz ointmentDevak Formulations ₹365.63 36.9% COSTLIER
-
insta senz ointmentShilpex Pharmysis ₹371.00 39% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken orally.
Fact: This medicine is for external use only and must not be swallowed. - Myth: More ointment means faster relief.
Fact: Applying more than directed does not improve results and may increase side effects. - Myth: It works immediately.
Fact: Pain relief may take several days to weeks of regular use.